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837 articles for “Clinical”
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A Study on Clinical Evaluation of Multi Intervention Therapy for Enhancing Quality of Life in Maintenance Hemodialysis Patients
Abstract: Patients with Chronic Kidney Disease (CKD) receiving maintenance hemodialysis often report a markedly impaired health-related quality of life, largely resulting from factors such as psychological distress, chronic inflammation, and poor nutritional status. Despite its importance as a clinical outcome, HRQOL assessment in dialysis patients has received limited attention. Strengthening comprehensive patient care and optimizing treatment strategies may help reduce complications and promote improved physical, mental, and social well-being. The present …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 69–81 Read article
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A Study to Assess the Add-on Impact of Ayurvedic Management along with Ongoing Conventional Treatment of Diabetes Mellitus: A Randomized Clinical Trial
Abstract: Diabetes affects millions and thus is a major public health disease among with adults aged 30+. Available treatment although helps but many develop other side effects to complicate the issue. Ayurveda offers options to manage diabetes without complications. Present study is to see the add-on effect of Ayurveda therapy among persons on modern medicines. Ayurveda D4 combination is Jamunbeej and Gudmarpatra 5 gm churna each before breakfast and dinner and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy Read article
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A Comprehensive Clinical Study with Ajamodakataila Matrabasti in the Management of Katigraha
Abstract: Katigraha is a Vataja Nanatmaja Vyadhi and it is explained as a condition characterized by Shula and restricted movements of Kati caused by Shuddha or Sama Vayu. Basti is considered as supreme therapy for Vatavyadhis. Matrabasti has dual action both Shodhana as well as Brimhana effect. In classics, no references are available for Ajamodakataila. So, it is considered as Anubhuta yoga and in the present study two ingredients are considered …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy Read article
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A Clinical Study on Comparing the Efficacy of Areca Catechu Mother Tincture with Areca Tea in Control of Blood Sugar Level Among Healthy Individuals
Abstract: Areca tea of Nivedan Nimpe is trending among diabetic group as preventive and curative diet. Areca Catechu is one of the Indian homoeopathic drugs. There is no authentic literature source to indicate the action of Areca against diabetes, so authors have investigated immediate action on blood sugar level among healthy individuals. Selection of volunteers was done on the basis of inclusion and exclusion criteria. Volunteers were randomly divided into three …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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Butrin Tackles Retinoblastoma – A Clinical Hypothesis †
Abstract: Breach of association of legumain protein activities to the corresponding cellular components results in over-expression of legumain, and constitutes a key biomarker for a variety of life-taxing sicknesses like cancer, Alzheimer’s/Parkinson’s and acute kidney injury. To suppress the functions of legumain, it is hypothesized that a water soluble and edible biomolecule, namely, butrin (7, 3’, 4’-trihydroxy flavanone-7, 3’-diglucoside) may have the therapeutic potential owing to its special ability to bind …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 26–30 Read article
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An Insilico Study of Isobutrin and Phosphorylase Kinase - A Ray of Hope for Psoriasis Patients – Clinical Hypothesis
Abstract: Psoriasis is a chronic, hyper-proliferative and inflammatory skin disease. Increased levels of the calmodulin-containing enzyme, namely, phosphorylase kinase (PhK), were observed in the human epidermis of the active psoriasis cases. Thus PhK is a potential biomarker for the diagnosis and progression of the skin disease, namely, psoriasis. The search for the potential molecules that could supress the over expression of PhK is underway and any break-through in this direction leads …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Enhancing Nursing Education Through AI-Driven Adaptive Learning Systems
Abstract: The integration of Artificial Intelligence (AI) in nursing education offers significant potential to enhance learning experiences by personalizing education, improving knowledge retention, and developing clinical competencies. This study evaluates the effectiveness of AI-driven adaptive learning systems compared to traditional lecture-based teaching methods in nursing education. A mixed-methods approach was used, with 200 nursing students participating in a quasi-experimental design. The intervention group (100 students) used AI-powered adaptive learning platforms for …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 · pp. 29–34 Read article
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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AI-Enhanced Interpretation of Cardiac Troponins: Toward Predictive Precision in Myocardial Injury
Abstract: Background: Cardiac troponins (cTn) represent the gold standard biomarkers for myocardial injury detection, yet their interpretation remains challenging due to various confounding factors and clinical contexts. Artificial intelligence (AI) technologies provide remarkable possibilities to improve the interpretation of troponin levels by utilizing pattern recognition, predictive modeling, and clinical decision-making support. Objective: This review examines the current state and future potential of AI-enhanced cardiac troponin interpretation, focusing on machine learning applications, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–9 Read article
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Patterns and Variations in Complementary Feeding Practices Among Mothers of Children Aged 6–24 Months Attending Immunization Clinics in Mandi Gobindgarh, Punjab, India
Abstract: Introduction: Complementary feeding introduces solid or semisolid foods to an infant’s diet while breastfeeding. In India, feeding infants and young children is determined by their socioeconomic status, cultural practices, and healthcare access. The study assesses the feeding practices of mothers with children aged 6–24 months who come for immunization at Mandi Gobindgarh, Punjab. Methods: A cross-sectional study was conducted with 350 mothers selected through systematic random sampling. A structured questionnaire …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 43–53 Read article
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A Review of Literature on Breast Cancer: Molecular Insights, Clinical Approaches, and Future Perspectives
Abstract: Breast cancer is the leading cause of morbidity and mortality in women globally. Although both men and women can get the condition, women are more likely to get it, and its prevalence has been rising globally in recent years. The epidemiology, risk factors, pathophysiology, diagnosis, treatment options, and survival rates of breast cancer are all examined in this review of recent research. Breast cancer can show up as a lump …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 15–20 Read article
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Caries-Preventive Effects of Self-Applied Subacidic 0.5% NaF-HF Gel via Toothbrushing in 7–8-Year-Old Schoolchildren: A Randomized Controlled Clinical Trial
Abstract: To assess the caries-preventive effectiveness of self-applied subacidic 0.5% sodium fluoride–hydrofluoric acid (NaF-HF) gel used during toothbrushing in children aged 7–8 years Objective: To assess the caries-preventive effectiveness of self-applied subacidic 0.5% sodium fluoride–hydrofluoric acid (NaF-HF) gel used during toothbrushing in children aged 7–8 years. Methods: This 1-year, multi-arm, double-blind, placebo-controlled, parallel-group randomized study evaluated the caries-preventive efficacy of self-applied 0.5% NaF-HF gel among primary schoolchildren. A total of 1200 …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 14–19 Read article
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Associations of C-RP with Renal Function Group and some Clinical Parameters in Patients with Dialysis in Iraq
Abstract: Introduction: Chronic kidney disease is a disease for which there are high mortality rates among those infected with many complications, including high rates of inflammation, anaemia, osteoporosis, and other complications. Methods: The current study was designed to evaluate the kidney functions of patients undergoing dialysis, where levels were evaluated Urea, Uric Acid, and Creatinine, in addition to C-Reactive Protein as a progressive of inflammation parameter, and to evaluate anaemia levels …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
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Polymer Based Optoelectronics in Clinical Application Treated with Sodium Fluoride and Aqueous Dimethyl Sulfoxide Solutions
Abstract: In polymer science, dimethyl sulfoxide (DMSO) and sodium fluoride (NaF) are frequently combined to dissolve, modify, or treat particular polymers, most notably in the processing of cellulose and the creation of polyvinylidene fluoride (PVDF) membranes. The viscosities, ultrasonic velocities, and sodium fluoride densities of aqueous solutions of dimethyl sulfoxide (DMSO) have been measured at T=303.15, 308.15, 313.15, and 318.15 K. Fluorides (such as NaF or TBAF) help break inter-chain hydrogen …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 20–29 Read article
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Personalized Medicine: the impact of ferrofluids, clinical procedures, strategies, applications,challenges, current trends, and reseach opportunities.
Abstract: Personalized medicine has shown progressive development and evolution in health care systems. It is considered as transformative emerging medicine encorporating advanced technologies including genomics, AI as thinking partner, and nanotechnology in a greater extent. The quest for painless injection, lesstoxicity, rapid cell separation, and gene sequencing make ferrofluid the focus of personalized medicine. Currently, magnetic nanoparicles and ferrofluides are becoming driving force of personalized medicine. However, contronlling and managing nanoscale …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 Read article
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Bridging the Theory-Practice Gap in Nursing Education in India: Exploring the Role of Simulation-Based Learning and AI-Driven Education
Abstract: The theory-practice gap in nursing education is a persistent issue that hinders the effective application of theoretical knowledge in clinical practice, ultimately affecting the clinical competence and decision-making skills of nursing graduates. This study explores the factors contributing to the theory-practice gap in nursing education in India and evaluates the potential of simulation-based learning (SBL) and artificial intelligence (AI)-driven education in bridging this gap. A mixed-methods approach was employed, involving …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article