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1680 articles for “BCS Class II/IV drugs”
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Integrative Perspectives on Lipoma: Traditional Therapeutics from Siddha, Ayurveda, and Unani with Biomedical Correlates
Abstract: Background: Lipoma is the most common benign soft tissue tumor, with an incidence of approximately 2 per 1,000 individuals annually. Modern biomedicine attributes its pathogenesis to genetic abnormalities like HMGA2 rearrangements and dysregulated adipogenesis via PPARγ pathways. Effective pharmacological therapies are lacking. Traditional Indian systems – Siddha, Ayurveda, and Unani – offer unique perspectives and non‑surgical approaches yet remain underexplored in integrative research. Objective: To critically evaluate the descriptions, pathophysiological …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 19–33 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Transforming Rare Disease Diagnosis with AI
Abstract: Artificial intelligence is changing healthcare fast. It is making diagnoses accurate, helping doctors get better results, and streamlining how care works. This paper looks at how AI shows up in healthcare right now – where it is already making a difference, what is working, and what is still tricky. The focus is on machine learning, natural language processing, and computer vision. Particular attention is given to using AI in diagnosing …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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A study on Controlling Artificial Heart
Abstract: The artificial heart has moved from a visionary concept to a clinically viable organreplacement technology, yet its longterm success hinges on the sophistication of its control architecture. This paper presents a comprehensive investigation of closedloop control strategies that enable an artificial heart to mimic the dynamic, beattobeat adaptability of its biological counterpart. We first construct a highfidelity cardiovascular model that integrates ventricular elastance, systemic and pulmonary vascular compliance, and realtime …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 1, 2026 · pp. 14–23 Read article
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Bridging Brain-Inspired Learning and Quantum Reasoning for Future AGI Systems
Abstract: This research paper presents a novel neuromorphic–quantum hybrid computing framework envisioned to advance intelligent systems toward artificial general intelligence. The architecture integrates brain-inspired spiking networks for adaptive, energy-efficient learning with quantum processors for non-classical optimization and reasoning. A shared synaptic–quantum memory layer enables dual information representation, while neuromorphic adaptive controllers provide real-time stabilization of noisy quantum circuits. While quantum processors offer features like superposition- enabled exploration and entanglement-based correlations that …
Published in Current Trends in Signal Processing · Vol. 16, Issue 1, 2026 Read article
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Assessing Land use Dynamics and Policies in the Waghur Basin Using Geospatial Techniques
Abstract: Changes in land use and land cover (LULC) are key indicators of human–environment interactions, especially in river basins where anthropogenic pressure is increasing. This study evaluated land use change and policy implications in the Waghur Basin, India, through a geospatial analysis of 35 years (1990–2025). Remote sensing and GIS-based supervised classification with the help of machine learning methods were applied to multi-temporal Land satellite images to create LULC maps and …
Published in International Journal of Land · Vol. 3, Issue 1, 2026 · pp. 38–49 Read article
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An Overview on Quantum dot technology in Temperature sensor design
Abstract: Quantumdot (QD) thermometry harnesses the sizedependent electronic structure of semiconductor nanocrystals to translate minute temperature variations into robust optical signals. In this work we present a systematic design framework for QDbased temperature sensors that integrates (i) bandgap engineering through precise colloidal synthesis, (ii) surfacestate passivation to suppress nonradiative pathways, and (iii) a planar photonicreadout architecture compatible with lowcost, CMOSfriendly fabrication. By exploiting the linear redshift of the photoluminescence (PL) peak …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 1, 2026 · pp. 10–17 Read article
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An Overview on MOSFET based Sensor Design
Abstract: In the past two decades the MOSFET has transformed from a simple switch in digital logic to an analog powerhouse that can be cofabricated with the sensing material on a single chip. MetalOxideSemiconductor FieldEffect Transistors (MOSFETs) have silently become the beating heart of modern sensor platforms, translating the faint whispers of physical, chemical, and biological phenomena into robust electrical signatures. This abstract surveys the latest advances that have turned the …
Published in Journal of Microelectronics and Solid State Devices · Vol. 13, Issue 1, 2026 · pp. 20–26 Read article
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Artificial Intelligence in Entomology: Global Advances, Applications, and Future Directions in Insect Research and Pest Management
Abstract: Artificial Intelligence (AI) is transforming entomology by enabling scalable, data-driven approaches to insect identification, ecological monitoring, and sustainable pest management. This review synthesizes recent global advances in AI applications across taxonomy, behavioral ecology, predictive modeling, and precision agriculture. Machine learning and deep learning techniques—including convolutional neural networks, acoustic classification models, and ensemble predictive algorithms—have demonstrated high classification accuracies (often exceeding 90% under controlled conditions) and improved early detection of pest …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 29–40 Read article
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Path Lab-AI: An Autonomous Framework for Error-Free Histopathology Slide Interpretation
Abstract: Path Lab-AI represents a fully autonomous platform for the analysis of histopathology slides with circumscribed structures, designed to obtain highly accurate results using diagnostic methods and avoiding the usual limitations of standard microscopy-based pathology. Leveraging recent deep learning and whole slide image (WSI) analysis innovations, our system takes advantage of automated WSI ingestion along with pre-processing steps to account for staining variability, remove artifacts, and localize tissue from background. Such …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 19–30 Read article
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Preoperative Use of Midazolam vs Dexmedetomidine for Anxiolysis in Day-Care Surgery
Abstract: Surgical procedures trigger significant fear and anxiety that can adversely affect physiological responses and recovery outcomes. This prospective, randomized, double-blinded clinical trial compared the anxiolytic efficacy and safety of intravenous midazolam and dexmedetomidine in 60 patients undergoing day-care surgery. Primary outcomes included anxiety scores measured by STAI and sedation assessed by the OAAS scale at multiple perioperative time points. Secondary outcomes assessed in the study included detailed evaluation of hemodynamic …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 7–12 Read article
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In Silico Identification of Therapeutic Agents for Dengue Virus by Molecular Docking
Abstract: The dengue virus causes serious health issues and a loss of quality of life. Dengue poses a yearly threat to half of the world’s population. The drugs that are based on allopathy are expensive and also exhibit toxic effects on tissues and biological activities. It is also generally accepted that most pharmacologically active drugs, including those derived from medicinal plants, are isolated from natural sources. The present study is directed …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 01–14 Read article
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Design and Implementation of a Polymer-Integrated IoT-Based Smart Intravenous Fluid Monitoring System for Patient Safety
Abstract: The intelligent healthcare systems rely more and more on the advanced materials and Internet of Things (IoT) technologies to improve patient safety, patient-centeredness, timeliness of care, clinical efficiency. This paper presents a polymer-enhanced IoT enabled automatic IV Fluid Level monitoring and notification system. The novel system is based on the use of polymer-encapsulated load-cell sensors and polymer-packaged electronic modules, which allow biocompatibility, long-term stability and easy sterilisation in medical environments. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 730–742 Read article
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Contribution of Dalak (Massage) in the Treatment of Waja-uz-Zohar (Back Pain): A Review
Abstract: Classical Unani literature presents a detailed understanding of Waja-ul-Mafasil (diseases of bones and joints) among which Waja-uz-Zohar (low back pain) has received extensive attention. Distinguished Unani physicians meticulously described its etiology, clinical features, complications, and treatment modalities. According to Unani theory Waja-uz-Zohar is defined as pain originating from the muscles, ligaments, and connective tissues surrounding the lumbar and lumbosacral regions. Prominent scholars, such as Ibn Sina and Zakariya Razi, attributed …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 1–6 Read article
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Survey in Hydrazine and its Preparation, Reactions, and Their Applications
Abstract: This review concerned with hydrazine derivatives; Hydrazine is an important chemical compound used in jet engine and rocket fuel. Therefore, the European Union prohibits its sales to the developing world at 100% concentration and only permits its sales at 20-25% concentration. It is also used in industry to produce chemicals for textiles, agriculture, photographic development materials, and blowing agents used in the manufacture of foam rubber. It is also used …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 27–34 Read article
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A Comprehensive survey of robust image quality metrics for satellite imagery
Abstract: Satellite imagery is essential for applications like environmental monitoring, urban development, precision agriculture, defence surveillance, and disaster response. The reliability of these applications is closely tied to the quality of the captured images, which may be compromised by atmospheric effects, sensor imperfections, compression artifacts, and transmission noise. As a result, accurate image quality assessment (IQA) is essential to ensure trustworthy analysis and informed decision-making in satellite-based systems. The distinctive properties …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 1, 2026 · pp. 7–20 Read article
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Depression Detection Using AI with Chatbot Support
Abstract: Depression is a major global health concern and a significant contributor to suicide rates worldwide. India reports a high number of suicide cases, making the early detection of mental distress and depression essential for timely intervention. This research presents an AI-based system for depression detection that integrates deep learning, natural language processing (NLP), and a chatbot for user support. The system analyzes facial expressions using convolutional neural networks (CNNs) and …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 14, Issue 1, 2025 · pp. 01–08 Read article
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Advancements in AI-Driven Sound Spectrogram Analysis: From Deep Learning to Quantum and Neuromorphic Processing
Abstract: The rapid advancement of artificial intelligence (AI) has significantly reshaped the field of audio signal processing, with sound spectrogram analysis emerging as a central research focus. Spectrograms provide a rich time–frequency representation of audio signals, making them particularly suitable for data-driven learning approaches. This paper presents an in-depth and original review of modern AI-based techniques applied to spectrogram analysis, highlighting their growing impact across critical application areas such as healthcare …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 13, Issue 1, 2026 · pp. 01–06 Read article
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In Silico Screening and Molecular Docking of Cynodon dactylon phytochemicals against COPD-Associated Proteins
Abstract: Chronic Obstructive Pulmonary Disease or COPD is a pulmonary disease that obstructs airways and alveoli accompanied by respiratory issues like emphysema and bronchitis. This disease is caused mainly by inflammatory responses of the body to foreign particles that enter the respiratory path including tobacco smoke, air pollutants and irritants. The hallmark of COPD is excessive inflammation caused by imbalance in protease anti-protease activity. Proteases like elastase breakdown the ECM of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Influence of ZycoTherm Dosage on Polymer Modified Bitumen and Marshall Performance of Hydrated Lime Incorporated Warm Mix Bituminous Concrete
Abstract: This study examines the effect of ZycoTherm on PMB 76-10 binder characteristics and the performance of PMB-based Bituminous Concrete (BC) Grade-II prepared at reduced mixing temperatures, with and without hydrated lime. PMB 76-10 was modified with ZycoTherm at dosages of 0.05%, 0.10%, 0.15%, and 0.20% by weight of binder and evaluated using conventional and residue-based tests. Increasing ZycoTherm dosage decreased penetration, while softening point, flash point, and elastic recovery increased, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 256–267 Read article