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167 articles for “signs and symptoms”
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Harmonizing Philosophies: An In-Depth Exploration of Homeopathic Case Management through the Lenses of Dr. Boenninghausen, Dr. Kent, and Dr. Boger
Abstract: This article examines the distinct yet converging philosophies of three pivotal figures in homeopathy: Dr. Boenninghausen, Dr. James Tyler Kent, and Dr. Cyrus Maxwell Boger. Each of these practitioners has significantly influenced homeopathic practice through their unique approaches to case management, symptom evaluation, and remedy selection. By analyzing a case of membranous dysmenorrhea drawn from Dr. Kent's archives, we applied methodologies from each of these pioneers, revealing how their philosophical …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 6–12 Read article
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Experimental Study on the Effect of Membranous Milkvetch and Ledebouriella divaricate Immunomodulatory Tablets on cytokine production in allergic rhinitis model mice
Abstract: We have established allergic rhinitis models for use in the treatment of allergic rhinitis with the help of the traditionall Koryo medicine administration, lade-screen Powder-extracted Membranous Milkvetch and Ledebouriella divaricate immunomodulatory tablet and the effect of lade-screen Powder on cytokine production in allergic rhinitis model mice. In the allergic rhinitis model, the administration of Membranous Milkvetch and Ledebouriella divaricate immunomodulatory tablets, along with Lade-screen Powder, demonstrated significant therapeutic effects. These …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Late Onset Ataxia: A Case Report
Abstract: 57-year-old man with no prior history of any illness presented with subacute onset of gradually progressive gait ataxia, upper limb incoordination and speech issues. There was history suggestive of orthostatic hypotension and erectile dysfunction. On examination, there was normal cognition with gaze evoked nystagmus, scanning speech and limb incoordination in the form of past pointing, dysdiadochokinesia, and tandem walking abnormality suggestive of pan cerebellar involvement. The patient was evaluated with …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 16–20 Read article
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Vitamin D in Americantitis population
Abstract: Neurasthenia is also known as Americantitis or nervosism where there is mechanical weakness of the nerves, characterised with symptoms like fatigue, anxiety, headache, heart palpitations, high blood pressure and depressed mood. Vitamin D is increasingly recognized as a critical nutrient with significant roles in various physiological systems, including the nervous, immune, and muscular systems. Emerging research highlights its direct impact on brain health, underscoring the importance of adequate Vitamin D …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 7–10 Read article
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Lower Genital Tract Infections in Pregnant Women: Epidemiology and Risk Factors Associated in Dakar, Senegal
Abstract: Vaginal infections are responsible for many problems in women of childbearing age and significantly influence pregnancy outcomes. This study sought to ascertain the prevalence of lower genital tract infections and the risk factors associated with them in pregnant women under observation at the Nabil Choucair Health Centre in Dakar, Senegal. This nine-month cross-sectional study, which involved women between 34 and 38 weeks gestation (WG), was carried out from July 2020 …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 47–59 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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Depression Detection Using Machine Learning: A Comprehensive Review
Abstract: Depression remains one of the most prevalent mental health conditions globally, yet it frequently goes undiagnosed due to the reliance on subjective evaluation methods. With the growing availability of digital behavioral data and significant progress in machine learning (ML), new possibilities have emerged for the automated detection of depression. This review offers a detailed examination of recent advancements in ML-driven approaches to identifying depressive symptoms. It covers a range of …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 3, 2025 · pp. 27–32 Read article
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Multiple Sclerosis: A Brief Overview of the Disease, Its Pharmacotherapy
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Holistic Ayurvedic Approach to Managing Vicharchika (Eczema): Insights from a Case Study
Abstract: Background: Eczema is a common skin condition characterized by inflammatory reactions, manifesting as erythema, scaling, and itching. Nipple eczema is a localized dermatitis involving the nipple and areolar region, characterized by erythema and scaling. It may be itchy and painful and occasionally affect non-atopic breastfeeding women. Eczema has quite a resemblance with Vicharchika in Ayurveda. Vicharchika is characterized by skin manifestations having the symptoms Kandu (itching sensation), Pidika (papule), Shyava …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 · pp. 1–9 Read article
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Mental Health Nursing Interventions in Schizophrenia Care: Effectiveness of Nurse-Led Strategies in Managing Schizophrenia Disorder
Abstract: Schizophrenia is a chronic and severe mental disorder characterized by disturbances in thought, perception, emotion, and behavior that significantly impair an individual’s functioning and quality of life. Mental health nurses play a pivotal role in the management of schizophrenia through comprehensive, patient-centered, and evidence-based interventions. This article critically examines the effectiveness of nurse-led strategies in managing schizophrenia disorder, focusing on pharmacological support, psychosocial interventions, psychoeducation, therapeutic communication, relapse prevention, and …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 1, 2026 Read article
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A Study to Assess the Effectiveness of Home-based Stretching Exercises on Joint Pain Among Clients with Osteoarthritis in Selected Old Age Home, Rajkot City, Gujarat
Abstract: Osteoarthritis (OA) is a commonly encountered condition in middle-aged and older individuals, marked by its slow development. Strengthening exercises targeting the quadriceps muscles, situated in the front thigh, can mitigate knee pain, and reduce disability associated with OA. The musculoskeletal system encompasses the bones of the skeleton, the joints where these bones connect, and the muscles responsible for enabling and regulating movement. The knee, the largest and most complex joint, …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 24–28 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article
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Cancer Chemotherapy-Induced Cachexia: Bridging Mechanisms, Management, and Future Therapies
Abstract: Involuntary weight loss, skeletal muscle atrophy, adipose tissue depletion, anorexia, and systemic inflammation are all symptoms of chemotherapy-induced cachexia, a complex illness. Although it is common, it remains poorly understood and is often referred to as an "orphan disease." This study covers the epidemiology, pathophysiology, clinical symptoms, diagnosis, treatment, and emerging treatment options for chemotherapy-induced cachexia. To comprehend the causes, clinical results, and therapeutic approaches, a literature-based synthesis of recent …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 17–26 Read article
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Assessment of Women's Knowledge of Mastitis at Indus International Hospital, Punjab
Abstract: Mastitis is a non-cancerous inflammatory condition of the breast, often resulting from infection, which can impact the mammary gland's structures. It is a relatively frequent condition, affecting between 5% and 33% of women during lactation at some point in their lives. Typical clinical signs include pain in one breast, redness (erythema), and swelling, often accompanied by flu-like symptoms such as fever, chills, and body aches. Upon examination, the affected breast …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article
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Influence of Social Media on Anxiety, Depression, and Loneliness: A Review
Abstract: Social media is a daily tool for communication, entertainment, and information exchange for millions of individuals worldwide. However, worries regarding its possible detrimental effects on mental health have surfaced, especially about despair, anxiety, and loneliness. This study's goal was to examine the connection between mental health issues and social media use. It highlights the clear connection between elevated psychological discomfort—such as anxiety, depression symptoms, loneliness, and overuse of social media—and …
Published in Recent Trends in Social Studies · Vol. 2, Issue 1, 2025 · pp. 22–27 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Intelligent Polymer-Integrated Wearable Platforms for Sustainable IoT and Predictive Health Monitoring for Migraine Detection
Abstract: Migraine is a neurological disorder, and its effect on the global workforce is resultantly significant. However, the fact of the matter is the absence of notable technological breakthroughs and the fact that the technology presently available is reactive, meaning it tackles the symptoms of the attack after the attack has occurred. The requirement for this paper is, therefore, the provision of an innovative approach, and this paper will describe the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 946–960 Read article
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Awareness Regarding Cervical Cancer among Women Attending a Selected Hospital in Lucknow, Uttar Pradesh: A Cross-Sectional Study.
Abstract: Cervical cancer continues to be a significant health concern, particularly in low- and middle-income countries like India, where it remains a leading cause of cancer-related deaths among women. Despite the availability of preventive measures such as the Human Papillomavirus (HPV) vaccine and screening techniques like Pap smears, a considerable gap in awareness persists. Limited knowledge of cervical cancer, its risk factors, symptoms, and preventive strategies hampers the effectiveness of early …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 19–24 Read article