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80 articles for “pharmaceutical standardization”
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Dawa Ul Misk Motadil Sada: A Review of a Standard Compound Unani Formulation for Khafaqān (Palpitation)
Abstract: Unani System of medicine is one in every of the ancient systems that overcomes untill date with its well-organized medicines derived from animal, plant and mineral resources. Over 2400 years past, the father of medicine Hippocrates practiced it; but His medication enclosed an excellent deal of ancient Egyptian medicine additionally as necessary elements of the traditional Mesopotamian traditions. In standard medicine, Palpitation is defined as an uncomfortable alertness of one’s …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2022 · pp. 1–4 Read article
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Design, Synthesis and Evaluation of Antitubercular Activity of Mannich Bases of Isoniazid-Containing Thiazolidin-4-one Rings
Abstract: Isoniazid (INH), the established antitubercular drug was selected as the lead for the design and development of antitubercular agents by many researchers. 4-thiazolidinones are well known heterocyclic compounds for their spectrum of biological activities such as antibacterial, antifungal [1], anticancer [2], antitubercular, anthelmintic, anti-inflammatory [3], analgesic [4], antithyroid, local anaesthetic, monoamine oxidase inhibition, anti-Toxoplasma gondii activity etc [5]. Modification of thiazolidinones via Mannich reaction to improve biological activity is also …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 1, 2016 · pp. 1–12 Read article
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Inventory of Healthcare Waste Generated at Kambia Government Hospital, Sierra Leone
Abstract: This research studies the categories and management practices of healthcare waste generated at Kambia Government Hospital and stresses the need for effective waste management to protect health and the environment. The waste is categorized into seven types: general, infectious, pathogenic, pharmaceutical, sharps, chemical, and liquid. Weekly assessments discovered fluctuations in waste generation, with general and infectious waste consistently comprising significant portions. Notably, sharps waste underscored the risks associated with injury …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 20–28 Read article
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Synthesis and Anti - Inflammatory Activity of A Novel Series of Quinoxaline2, 3-Dione Derivatives
Abstract: Aim: The aim of the present study is to synthesis and screening the anti-inflammatory effect of novel series of quinoxaline 2, 3Dione derivatives containing a 4-thiazolidinone (T1-T5) nucleus. Method: Thesynthesis of thiazolidinones by reacting N-substituted arylidene/heteroarylidene Quinoxaline 2, 3-dione with thioglycollic acid in the presence of dry benzene. All the title compounds were tested for their anti-inflammatory activity of the synthesized compounds was evaluated by Carrangeenan induced paw edema method …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 7–13 Read article
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Electronic Common Technical Document (eCTD): A Review of History, Benefits of Implementing, Challenges, Modules and Risks Involved in eCTD Publishing
Abstract: Electronic Common Technical Document (eCTD) is a topic of increasing interest in the pharmaceutical environment. eCTD is an interface for the pharmaceutical industry to agency transfer of regulatory information. Since June 2003, applicants have had the option of submitting an eCTD in parallel with the paper submission (Common Technical Document), following sign-off by the International Conference on Harmonization Steering Committee of the eCTD Specification document at Step 4. It is …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 3, 2016 · pp. 1–16 Read article
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Ludiflash—A Novel Excipient for Patient Friendly Dosage Form
Abstract: Consumers want a pleasant-tasting and fast-acting tablet that can be taken anywhere, anytime without the need of water. They want such a tablet that completely disintegrates within moments, with no bitterness or chalky aftertaste. FDTs fast disintegrating tablets are the dosage form which will disintegrate in mouth within seconds without need of water. This type of property in dosage form can be attained by addition of different varieties of excipients. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 2, 2017 · pp. 5–7 Read article
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Formulation and Evaluation of Transungual Drug Delivery of Fluconazole Using Permeation Enhancers Screened by Hydration of Nail Plate
Abstract: The objective of the work was to formulate nail lacquer containing fluconazole an antifungual drug for the treatment of onychomycosis. Onychomycosis, a common fungal nail infection affects the people. Topical and ungual therapy is limited because of the poor permeation of the drug through nail plate. Film base was prepared using varying concentration of cellulose acetate and ethyl cellulose as polymers. The permeation enhancers were screened by nail plate hydration. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 32–45 Read article
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In vitro Quality Control Testing: A comparative Study of Jan Aushadhi with Different Brands of Metformin Tablets Available in India
Abstract: Metformin hydrochloride is an oral anti-diabetic drug used mainly to treat type-II Diabetes Mellitus and it is widely available in different brands in the market, making it challenging to select the safe, effective and economic one. The endeavour of this experiment was to compare and assess the quality standard of the Jan Aushadhi medicine with a different brand of the metformin hydrochloride tablet available in India. For evaluation of the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 32–37 Read article
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Hepatoprotective Activity of Japanese Cedar (Cryptomeria japonica) against Carbon Tetrachloride Induced Toxicity
Abstract: Liver is a vital organ which plays a major role in metabolism and excretion of xenobiotics from the body. Liver injury or liver dysfunction is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. Liver cell injury caused by various toxic chemicals and excessive alcohol consumption and microbes is well studied. The available synthetic drugs to treat liver disorders …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 2, 2016 · pp. 6–9 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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Role of Clinical Pharmacists During Cardiopulmonary Resuscitation in Intensive Care Units and Emergency Departments: A Narrative Review
Abstract: Cardiopulmonary resuscitation (CPR) represents an essential emergency procedure designed to reestablish spontaneous circulation and enhance survival rates among individuals suffering cardiac arrest. Successful resuscitation necessitates prompt clinical judgment, expeditious pharmaceutical interventions, compliance with advanced cardiovascular life support (ACLS) guidelines, and synchronized interprofessional collaboration. During recent decades, clinical pharmacists have gained greater incorporation within emergency response and resuscitation units owing to their specialized knowledge in medication oversight, pharmacotherapeutic enhancement, and patient …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 4, Issue 1, 2026 · pp. 12–25 Read article
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Anti-Escherichia coli Potentials of a Novel Chemical Compound 1-(2-hydroxy-1, 2-diphenylethylidene)-3-phenylthiourea
Abstract: Inspiration from the anti-infective excellence (anti-bacterial, anti-fungal, anti-viral, and anti-malarial) of Schiff’s base molecules as well as knowing the rising importance of low-molecular-weight ligands (LMWL), the present research involved the development of novel Schiff’s base compound utilizing very basic laboratory components; 1-phenylthiourea and benzoin using the conventional synthesis technique. The compounds were comprehensively characterized through sophisticated instruments and further screened for anti-microbial activity against pathogenic Escherichia coli (E. coli, MTCC …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 9–12 Read article
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
Abstract: The present study was performed in pylorus ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 42–49 Read article
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Evaluation of Intravenous Admixtures in Tertiary Care Teaching Hospital
Abstract: Intravenous medication continues to expand and there is an increase in number of medications administered to each patient. There are no specific studies to identify the incompatibilities that commonly occur in hospitalized patients while administering these intravenous admixtures. The main aim of the study was to assess the potential incompatibilities associated with intravenous admixtures in tertiary care teaching hospital. The data for the present study were collected by patient interview …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 2, 2015 · pp. 9–16 Read article
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Factors Affecting Shear Stress on Tablet Hardness and Disintegration
Abstract: The quality and effectiveness of pharmaceutical tablets depend heavily on several factors influencing shear stress on tablet hardness and disintegration. These factors include formulation composition, wherein the selection and concentration of excipients and active ingredients affect how the tablet material responds to shear stress. Additionally, the compression force, speed, and duration during tablet compression are critical, impacting tablet hardness and disintegration properties. Tablet geometry and design, along with tablet press …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 1–19 Read article
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Consumer Misuse of Cosmeceuticals and Its Role in Adverse Skin Reactions
Abstract: Cosmeceuticals represent a rapidly expanding category of products positioned between cosmetics and pharmaceuticals, offering both aesthetic and therapeutic benefits. However, their widespread availability, aggressive marketing, and perception as inherently safe have contributed to increasing instances of consumer misuse. Misuse includes over-application, inappropriate combinations, prolonged unsupervised use, and use of high-potency active ingredients without dermatological guidance. Such practices have been strongly associated with a broad spectrum of adverse cutaneous reactions ranging …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 · pp. 1–16 Read article
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Synthesis, Characterization and Antibacterial Evaluation of Novel Canola Oil-Based Poly-(Citrate/Succinate)-amide Incorporated with Zn (II) and Ni (II) Metal Ions
Abstract: This present research study is to fabricate efficient metal-incorporated Canola oil (CO) polymers synthesised using dicarboxylic acids – Citric acid (CA) and Succinic acid (SA). The research mainly highlights the fabrication of polymeric materials using CO via a safer chemical synthesis route with less toxic reactants and minimal solvent/diluent to accomplish sustainability, adopting the green chemistry principle. Divalent Zinc (Zn) and Nickel (Ni) were incorporated in the poly-(Citrate/Succinate)-amide matrix, Ni …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 45–69 Read article
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Pharma Tech: Leveraging Software for Drug Development & Clinical Research
Abstract: The pharmaceutical sector is progressively adopting software solutions to enhance the drug development process and optimize clinical research results. Drug development is a time-consuming, expensive, and intricate process that traditionally requires extensive laboratory research, preclinical testing, and several stages of clinical trials. Software tools are revolutionizing these stages by improving efficiency, minimizing errors, and speeding up timelines. During preclinical testing, predictive software tools are used to model toxicological effects and …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 11–19 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article