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Journal of Polymer & Composites Original Research

Synthesis, Characterization and Antibacterial Evaluation of Novel Canola Oil-Based Poly-(Citrate/Succinate)-amide Incorporated with Zn (II) and Ni (II) Metal Ions

  1. Juhi Gupta Bioinorganic Research Lab, Department of Chemistry, Jamia Millia Islamia,New Delhi
  2. Md. Ikbal Ahmed Talukdar Bioinorganic Research Lab, Department of Chemistry, Jamia Millia Islamia,New Delhi
  3. Archana Chakravarty Scholar, Department of Chemistry, Independent Researcher, New Delhi
  4. Nitu Singh Scholar, Department of Chemistry, Independent Researcher, New Delhi
  5. Janesh Gautam ICMR, National Institute for Implementation Research on Non-Communicable Diseases, Jodhpur
  6. Suresh Sagadevan Nanotechnology and Catalysis Research Centre, University of Malaya, Kuala Lumpur
  7. Athar A. Hashmi Bioinorganic Research Lab, Department of Chemistry, Jamia Millia Islamia, New Delhi

Abstract

This present research study is to fabricate efficient metal-incorporated Canola oil (CO) polymers synthesised using dicarboxylic acids – Citric acid (CA) and Succinic acid (SA). The research mainly highlights the fabrication of polymeric materials using CO via a safer chemical synthesis route with less toxic reactants and minimal solvent/diluent to accomplish sustainability, adopting the green chemistry principle. Divalent Zinc (Zn) and Nickel (Ni) were incorporated in the poly-(Citrate/Succinate)-amide matrix, Ni being less explored till now. The composition, skeletal system and properties of Zn and Ni incorporated poly-(Citrate/Succinate)-amide were analysed by UV-visible, band gap energy, FTIR and NMR (1H/13C) spectroscopic studies along with their physio-chemical properties using standard methods. The size, stability and surface charge distribution were studied using DLS-Zeta, which has not been reported previously. Notably, the study established a slight comparison between the metal incorporated poly-(Citrate/Succinate)-amide. Metal-incorporated CO poly-(Citrate/Succinate)-amide were also examined for in-vitro antibacterial activity against Gram-positive (G+ve) B. cereus (MCC2243) and Gram-negative (G-ve) E. coli (MCC2412) bacteria using conventional procedures. The research analysis demonstrated that the antibacterial activity was enhanced when divalent Zn and Ni ions were introduced into the polymer matrix more than virgin canola oil, with more efficacy registered for Zn than Ni incorporated poly-(Citrate/Succinate)-amide and the mechanism for the same have also been discussed here. This research contributes to the development of sustainable biomaterials with promising applications as antibacterial coatings, biomedical and pharmaceutical, offering a greener and safer alternative to conventional synthesis methods.

Keywords

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