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177 articles for “in-silico studies.”
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Effects of Sub-Zero Temperatures on the Viscoelastic Properties of Magnetorheological Elastomer
Abstract: Magnetorheological elastomers (MREs) are smart materials capable of tuneable stiffness and damping under applied magnetic fields. This renders the material as a promising candidate for adaptive vibration control and semi-active engineering applications. While their behaviour at elevated temperatures has been widely explored, limited attention has been given to their performance under sub-zero conditions, which are critical for cold-environment applications. As this has become an important concern, the study investigates the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 326–340 Read article
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Impact of Spacer Engineering on SOI Junctionless FET Performance Using TCAD Simulation
Abstract: In this paper, the impact of spacer engineering on 10 nm gate length planar SOI (Silicon On Insulator) junctionless transistor performance is studied using Sentaurus TCAD simulator. Spacer length and spacer permittivity of the device are taken as two controllable parameters. DC performance metrics, ION, IOFF, ION/IOFF ratio, unity gain frequency (fT) and non quasi static delay (NQS) are investigated for various spacer lengths and spacer permittivity. The simulation results …
Published in Journal of Materials & Metallurgical Engineering · Vol. 6, Issue 2, 2016 · pp. 42–52 Read article
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Fabrication of Low-Cost and High-Efficiency Crystalline Silicon Solar Cells Using Polymeric Carrier Selective Contacts
Abstract: Crystalline silicon (c-Si) solar cells are the leading choice in the photovoltaic market due to their dependability and long-term stability, but lowering production costs and increasing efficiency remain key issues. Organic semiconductors use carrier-selective contacts based on doped amorphous silicon layers and transition metal oxides to simplify and lower the production costs of efficient crystalline silicon solar cells. Polymers are rapidly being used in photovoltaics as flexible substrates, photoanode films, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 124–131 Read article
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Comparative Study of Drain Current of Symmetric and Asymmetric DG-MOSFET with Simulation in Silvaco TCAD Software
Abstract: One of the most attractive and promising devices for the nanoscale devices is the double gate MOSFET. The double gate MOSFET can control the Si channel very efficiently and it chooses a very small width of the Si channel. It controls the Si channel by applying gate contact to either side of the channel. The idea of controlling the S channel in such a way reduces the short channel effects …
Published in Journal of Semiconductor Devices and Circuits Read article
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Emerging Therapeutic Discovery Against Escherichia coli Infection by Rational Inhibition of Fatty Acid Responsive Transcription Factor: Theoretical Molecular Investigations of Some Metabolites as Inhibitors of Fatty Acid Metabolism Protein
Abstract: For the discovery of effective agent for overcoming resistance against Escherichia coli (E. coli) bacteria by modulating Fatty Acid Metabolism Protein (FadR)—a Fatty Acid Responsive Transcription Factor. The present study involved discovery of some metabolites of furan, furan-2-yl, macrolactin, and chromene scaffold via in silico structure-based drug design (SBDD) technique by utilizing the Maestro 9.1 software. The study will provide clues, motivate, and throw light on imperative aspects for the …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 1–7 Read article
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Structure–Property Relationships in Poly (N isopropylacrylamide) Hydrogels: Toward Thermoresponsive Polymer Composites
Abstract: Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels can shift from solid to gel and back again at body temperature. Due to their lack structural integrity, thermal stability, and mechanical strength, they are difficult to use. This study mixed PNIPAAm with biocompatible fillers like chitosan and silicon nanoparticles to create hydrogels with superior structure-property correlations. Free radical polymerization with ammonium persulfate/TEMED initiator and N,N′-methylenebisacrylamide crosslinker produced the composites. Scanning electron microscopy showed a denser, interconnected …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 884–895 Read article
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A Study of Carbon Nanotubes in Photovoltaic Devices
Abstract: AbstractArrays of periodic one-dimensional nano materials provide light–matter interaction in terms of tunable optical properties which are attractive for planning efficient optoelectronic devices. This paper is based on n-i-p thin-film amorphous silicon utilizes scaffolds of vertically aligned carbon nanotube (CNT) array for a fabrication of bottom-up grown Nano pillar (NP) array solar cells. The varying effect of the CNT extent over a wide range from 800 to 2000 nm on …
Published in Trends in Opto-electro & Optical Communication · Vol. 10, Issue 1, 2020 · pp. 1–13 Read article
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In silico Analysis of nsSNPs in the Human ACTN4 Gene associated with a Steroid-Resistant Nephrotic Syndrome
Abstract: The main motive of this study is to discover nsSNPs of ACTN4 gene through various insilico views. ACTN4 is one of the proteins that play a leading role in cellular pathways by altering cytoskeletal behaviour associated with steroid-resistant nephrotic syndrome. Data of ACTN4 was collected from NCBI dbSNP and Uniport KB and further used to explore adverse outcome using SIFT, PolyPhen, PROVEAN and SNAP2.Out of 11 nsSNPs selected in this …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 43s–52s Read article
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Enhancements in Titanium Matrix Composites: A Multifaceted Exploration of Various Structural Ceramics Reinforcement
Abstract: This research study delves into the comprehensive exploration of Titanium Matrix Composites (TMCs) reinforced with Silicon Carbide (SiC), Alumina (Al2O3), and Boron Nitride (BN). The investigation is structured into three key phases, each addressing essential aspects of TMCs: Phase 1 involves materials and manufacturing, where TMC coupons were fabricated through the stir casting technique with varying compositions of aluminum and silicon carbide. Phase 2 focuses on characterization and defect detection, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 83–94 Read article
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Performance of Cr3C2-25(Ni-20Cr) and Ni-20Cr Coatings on T22 Boiler Tube Steel in Simulated Boiler Environment
Abstract: Corrosion of metals is a dangerous process, due to which there is loss of metal by the attack of corrosive agents. The high temperature corrosion causes fast material degradation which results in failure of components. Boiler tubes in the thermal power plants are subjected to corrosion due to high temperatures. Thermal spray coatings have been used to reduce the corrosion of boiler tubes. In this research paper an attempt has …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 3, Issue 2, 2016 · pp. 19–26 Read article
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Enhancing Mechanical Performance in Reinforced Hybrid Composites using Silicon Carbide and Aluminium Oxide Fillers
Abstract: Hybrid composites are becoming useful because they have better qualities than regular composites. This study examines the conventional properties of composites that utilise SiC and Al2O3 as filler components. Kevlar, S-glass, and sisal fibers at 90° and 0°, followed by additional layers of S-glass and Kevlar. To make sure that the material qualities were the same throughout, the resin and fibre layers were arranged in an alternating pattern. Mechanical testing …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 934–945 Read article
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Performance and Analysis of 6T, 8T & 10T SRAM Cell in 28nm Technology
Abstract: Technology scaling into deep sub-micron regimes has significantly increased the design challenges of Static Random Access Memory (SRAM), particularly at the 28 nm technology node. As transistor dimensions shrink, SRAM cells become more vulnerable to stability degradation, leakage current, process variations, and reduced noise margins, which adversely affect overall memory performance and reliability. The conventional 6T SRAM cell remains widely used due to its compact structure and high storage density; …
Published in Journal of VLSI Design Tools and Technology · Vol. 16, Issue 2, 2026 · pp. 12–18 Read article
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In silico Prediction of Two New Conformations of Aβ42 Peptide and Possible Mechanism of Their Aggregation
Abstract: Alzheimer’s disease is one of the most studied neurodegenerative diseases. The cause for most cases of this disease is unknown. However, there are many hypotheses regarding the progression of this disease. One of the hypotheses is the amyloid hypothesis. Amyloid precursor protein present on chromosome 21 is cleaved by β and γ sectretases. The cleaved fragments of this protein, nearly 36–43 residues long aggregates and are deposited as plaque in …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 1–7 Read article
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Studies of CRISPR/CAS 9 Gene Interactions in Streptococcus pyogenes
Abstract: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/cas9/single guide RNA (sgRNA) system is a DNA editing system in mostly studied in prokaryotes. Studies of CRISPR/cas9 gene interactions in Streptococcus pyogenes has been conducted using in silico approaches in the present research. Proteins like DNA polymerase I (polA), NAD-dependent DNA ligase LigA (ligA), Translaldolase (tal), Thymidine kinase (tdk), Streptococcal exotoxin I (speI), Phage associated protein (SPy_0679) and Hypothetical proteins like SPy_1047, SPy_1048, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 32–38 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Finite Element Analysis of Spur Gear Manufactured of Al7475-SiC Composites
Abstract: The spur gear is used in power transmission systems in industrial and automotive sectors. But sometimes, these gears have problems with their teeth due to excessive stress and wear. Some gears don't work as well, so in the present work better material is used to make them work well. Composite materials, which is known for their optimal strength-to-weight ratio and weight reduction benefits. So, these materials are considered substitutes for …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 279–284 Read article
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Flame Spraying of Polymer-Abrasive Composites
Abstract: Polymer-based abrasive tools are distinguished by higher elasticity and resistance to chemically active media compared to tools with metal and ceramic binders. The former are effective at processing complex-profile and non-rigid surfaces. Tools based on coatings containing abrasive phenol- formaldehyde/epoxy resins and vulcanites are characterized by high cost and toxicity. In this paper, a study of composite flame-sprayed coatings, consisting of thermoplastic polymers and silicon carbide (volume ratio of 50-50), …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 96–104 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Exploring Abies grandis phytocompounds potential by in silico analysis targeting on the 5P9J Protein
Abstract: Blood Cancer, also popular with name ‘Hematologic cancer’ have variety of types: Leukaemia, Lymphoma, Myeloma, uncontrolled multiplication of blood cells mainly affecting to bone marrow and blood cells (White Blood Cells). Lymphoma, originating from lymphatic system resulted in uncontrolled growth and instead of normal apoptosis development of tumor. Myeloma, uncontrolled formation of malignant plasma cells leads disrupting production of healthy blood cells. This situation creates variety of diseases like anaemia, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Enhancing The Mechanical Performance of Al6061/Graphite Composites Reinforced with Sic and Aluminium Oxide Processed by Stir Casting
Abstract: The study investigates the mechanical properties of aluminum alloy Al6061 reinforced with varying proportions of silicon carbide (SiC) (0 wt%, 4 wt%, 5 wt%, and 6 wt%) and aluminum oxide (Al₂O₃) (0 wt%, 4 wt%, 3 wt%, and 2 wt%), with a constant addition of 1 wt% graphite. The composites were fabricated using the stir casting process, an efficient and economical method for uniformly distributing ceramic reinforcements within the metal …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 66–74 Read article