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245 articles for “agent evaluation”
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Effect of Local Application of Phenytoin on Wound Healing in Surgical Wounds: A Scientific Review
Abstract: Surgical wound healing is a dynamic biological process influenced by local tissue response, vascularity, infection control, and systemic patient factors. Delayed wound healing contributes significantly to postoperative morbidity and healthcare costs. Phenytoin, a hydantoin derivative traditionally used as an antiepileptic agent, has demonstrated unexpected wound-healing properties when applied topically. This review critically evaluates experimental and clinical evidence regarding the role of locally applied phenytoin in enhancing wound healing in surgical …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 15–19 Read article
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Investigation on the Efficacy of Leaf Extract of Goat Weed, Ageratum conyzoides on NR Biophysiological Characteristics of Black Gram Vigna mungo Infected with Root–Knot Nematode Meloidogyne incognita
Abstract: Root-knot nematodes, Meloidogyne sp. are economically important plant pathogens affecting root system that can be managed by cultural practices, chemical nematicides and resistant cultivars. Use of nematicides for the management of root knot nematodes are being restricted due to environmental and human health concerns in addition nematicides often do not provide long term suppression of the pathogens. Therefore, there is a need to develop alternate ecofriendly management strategies for the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 4, Issue 1, 2014 · pp. 5–9 Read article
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Development and Evaluation of a Cost-Effective UV-Protective Cream Containing Para-Aminobenzoic Acid and Aloe Vera for Indian Climatic Conditions.
Abstract: The increasing incidence of ultraviolet (UV) radiation-induced skin disorders has heightened the demand for effective, affordable photoprotective agents, especially in countries with high sun exposure such as India. This study aimed to develop a cost-effective and efficient UV-B protective cream formulation suitable for populations in Indian latitudes. Para-aminobenzoic acid (PABA) was selected as the primary sunscreening agent due to its high UV-B absorption efficiency, low toxicity, and affordability compared with …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 7–18 Read article
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Autonomous Agentic AI for Adaptive Cure Optimization and Defect Prevention in Thermoset Polymer Composite Manufacturing
Abstract: Thermoset polymer composites occupy a central position in modern structural manufacturing, from aircraft fuselages to wind-turbine blades. Despite progress in resin chemistry and fiber architecture, the “cure process” that transforms compliant preforms into load-bearing structures remains difficult to manage. Manufacturers encounter ‘voids’, “interlaminar delaminations”, and “spring-back distortion” when curing complex or thick-section parts. The cause is not ignorance of the relevant physics, but rather that ‘temperature’, ‘chemistry’, ‘rheology’, and ‘mechanics’ …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 301–320 Read article
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The Concept of Guillain-Barré Syndrome (GBS) in Unani Medicine and the Potential Role of Unani Pharmacology in Its Management
Abstract: Introduction: Guillain–Barré Syndrome (GBS) is an autoimmune neurological disorder characterized by progressive muscle weakness and paralysis due to immune-mediated damage to the peripheral nervous system. Conventional treatments focus on immunotherapy and supportive care, but alternative approaches, such as Unani Medicine offer promising holistic management strategies. Unani Medicine attributes GBS to humoral imbalance, particularly an excess of Balgham (Phlegm) affecting nerve function, leading to weakness and dysfunction. Objective: This study aims …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 32–52 Read article
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Optimizing Mechanical and Durability Properties of Eco-Friendly Composite Materials Using Recycled Fillers and ML Techniques
Abstract: The increasing demand for sustainable construction materials has intensified the exploration of recycled fillers as partial or full replacements for natural aggregates in composite materials. This study investigates the mechanical and durability performance of polymer matrix composites incorporating processed recycled fillers derived from construction and demolition (C&D) waste. Three distinct processing methods were employed to prepare the recycled fillers: untreated (URF), single processed (SPRF), and double processed (DPRF), with replacement …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 269–309 Read article
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Biodisintegrable Low-Density Polyethylene (LDPE)/Sago Starch (SS) Composites for Food Packaging Applications
Abstract: Research scientists are very interested in polysaccharide-filled plastics as a way to create a biodisintegrable polymer composite. The goal of the current study is to employ SS to create a biodisintegrable polymer composite, which could pave the way for a more user-friendly polymer composite in the future. In this study, LDPE/SS biodisintegrable composites were created by physically blending SS and LDPE in a Brabender mixer. The effects of varying the …
Published in Emerging Trends in Chemical Engineering · Vol. 9, Issue 3, 2022 · pp. 1–12 Read article
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Pre-extension Demonstration of Improved Teff Technologies at Shashogo District, Hadiya Zone, Southern Ethiopia
Abstract: Teff is a highly important crop in Ethiopia in terms of both production and consumption. Population growth, low incomes, and urbanization have all contributed to an increase in demand for teff, which is predicted to continue. However, the teff production system largely depends on traditional methods. As a result, the crop yield has not reached at the desired level. Therefore, the pre-extension demonstration of improved teff technologies was conducted at …
Published in Research & Reviews : Journal of Ecology · Vol. 12, Issue 1, 2023 · pp. 33–39 Read article
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A Clinical Study to Evaluate the Efficacy of Durvadi Taila in the Management of Muladhar Chedan/Yonikshat w.s.r. to Episiotomy Wound
Abstract: Background: Episiotomy is a surgically planned incision on the perineum and the posterior vaginal wall during the second stage of labor. It is more prone to an infection that is why it requires wound care and maintenance. Episiotomy can be compared to Chhina Vrana (a kind of Sadhyo Vrana). Durvadi tail a have been mentioned in Yogratnakar as vrana ropak in the treatment of Sadhyo vrana. Aim: Clinical evaluation of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2017 · pp. 8–14 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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Experimental Study on Cyanoacrylate as Wound Adhesive
Abstract: Cyanoacrylates (CAs) have been widely used as surgical glues; however, the high cost of medical CA-based glues limits their use in developing countries. Another possible alternative is the low cost α-CAs which are normally used in commercial glues. The lack of toxicity studies of such agents is considered the main obstacle in their medical application. In the present study, we have evaluated the toxicity profile of commercial glue in comparison …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 10–14 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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Evaluation of Bio-Based Polymer Composites Containing Guava Leaf Extract for Antimicrobial Functionality
Abstract: This study explores the formulation of an herbal soap using guava leaf extract as a primary ingredient. Guava leaves are a rich source of biopolymers like pectin and cellulose, which may contribute to the binding properties in the soap. The antimicrobial activity of the soap was evaluated against common skin pathogens (Staphylococcus aureus, Trichoderma spp., Aspergillus spp.). The formulated soap exhibited inhibitory effects against all tested pathogens. The weight, foaming …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 875–880 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article
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Role of Netra Tarpana with Triphala Ghrita in Dry Eye: A Clinico-Pathological Evaluation
Abstract: Dry eye syndrome is a very common condition that is characterized by a disturbance of the tear film. There is not a single entity which can be compared as dry eye but a group of diseases or stages of diseases which are more or less similar to dry eye like Sushkaksipaka, Pothaki, Suktika. Preservative-free tear substitutes are the first step in medical management of DED which increases humidity and improves …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 3, 2015 · pp. 1–8 Read article
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Excoecaria agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies
Abstract: Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
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Design, Synthesis and Evaluation of Antitubercular Activity of Mannich Bases of Isoniazid-Containing Thiazolidin-4-one Rings
Abstract: Isoniazid (INH), the established antitubercular drug was selected as the lead for the design and development of antitubercular agents by many researchers. 4-thiazolidinones are well known heterocyclic compounds for their spectrum of biological activities such as antibacterial, antifungal [1], anticancer [2], antitubercular, anthelmintic, anti-inflammatory [3], analgesic [4], antithyroid, local anaesthetic, monoamine oxidase inhibition, anti-Toxoplasma gondii activity etc [5]. Modification of thiazolidinones via Mannich reaction to improve biological activity is also …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 1, 2016 · pp. 1–12 Read article
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Formulation Development of Otic In Situ Gel containing Lomefloxacin Hydrochloride
Abstract: The present study was aimed at formulation development of a sustained release otic in situ gel of lomefloxacin hydrochloride for the treatment of chronic suppurative otitis media. Poloxamer 407 was used as the thermoreversible gelling agent. Poloxamer concentration in the range of 15–20% w/v was tried. Poloxamer 407 at 16% w/v gave satisfactory in situ gel forming formulations as it gelled near physiological temperature. Poloxamer 407 with various viscosity enhancing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 1, 2016 · pp. 20–29 Read article
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Formulation and Evaluation of Gastro retentive Effervescent Floating Tablets of Famotidine: Effect of Formulation Variables and In Vitro In Vivo Evaluation
Abstract: Gastro retentive effervescent floating tablets of famotidine were developed in an attempt to sustain the drug release as well as to prolong the presence of dosage form in the stomach or upper small intestine until drug is completely released in desired period of time from the formulation with special emphasis to the effect and concentration of different polymers on drug release and floatation. Tablets were prepared by direct compression method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 13–29 Read article