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494 articles for “Validation Study”
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Predictive Maintenance Strategies for Safety-critical Mechanical Systems
Abstract: Ensuring the reliability and safety of industrial systems is essential, especially in high-risk sectors such as aerospace, manufacturing, and energy. Predictive maintenance (PdM) has become a crucial approach for minimizing operational failures and improving maintenance efficiency. This research introduces an advanced PdM framework that enhances industrial safety by integrating Internet of Things (IoT) technology, machine learning (ML), and big data analytics. By enabling real-time monitoring and predictive fault detection, this …
Published in Journal of Industrial Safety Engineering · Vol. 12, Issue 1, 2025 · pp. 12–17 Read article
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Comparative Analysis of Bioactive Phytochemical Profiles of Moringa Oleifera and Aegle Marmelos Grown in Bundelkhand
Abstract: A comparative analysis of the bioactive phytochemical profiles of Moringa oleifera and Aegle marmelos grown in the Bundelkhand region was conducted to explore their potential health benefits. These properties make healing plants valuable in herbal medicine, supporting various aspects of health and well-being. The study aimed to determine the differences in the concentrations of bioactive compounds such as phenolic, flavonoids, alkaloids, and vitamins C and E in the leaves and …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 14–24 Read article
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Seasonal Variation in the Weibull Parameters from In Situ Measurements and Model: A Case Study in the Bay of Bengal
Abstract: Seasonal variation of wind speed (U10) and its distribution are essential for the design of wind energy converters (WEC). In this study, year-round wind speed observations from a deepwater moored buoy at a location in the Bay of Bengal are used to assess the potential for wind power generation and are used to validate the ERA5 model. Model-U10 distribution is confined to low wind speeds with high occurrence in the …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 1, 2024 · pp. 30–40 Read article
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Repurposing Liv-52 For Primary Sclerosing Cholangitis: A Computational Docking And Pharmacokinetic Study To Evaluate Its Bile Flow-Regulating Potential
Abstract: Primary Sclerosing Cholangitis (PSC) is a long-term liver disease where the bile ducts become inflamed and scarred over time. This scarring can block the flow of bile, leading to liver damage and, eventually, liver failure. The etiology of PSC remains largely unknown, and current treatment options are limited, highlighting the need for novel therapeutic strategies. This study aims to repurpose Liv-52, a traditional herbal formulation known for its hepatoprotective properties, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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A Bio-Bibliometric Analysis of Dr. Suprabhat Mukherjee, a Pioneer of Innovative Approach for Colon Cancer Treatment Using Fluids of Custard Apple (Annona Reticulata) Seeds
Abstract: Dr. Suprabhat Mukherjee, associated with Kazi Nazrul University (KNU), West Bengal, India, is a globally recognized immunobiologist, and a celebrated Indian scientist cum researcher for his contributions in Corona Vaccine, and Colon Cancer. This study covers his 154 research publications in various forms of published documents during 2010–2024. Personal information and data about research contributions, have been collected from the bibliographic databases like Google Scholar (GS), Research Gate (RG), and …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 1, 2025 · pp. 50–68 Read article
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AI-Powered Drug Delivery: Revolutionizing Formulation Science
Abstract: Artificial Intelligence (AI) is emerging as a groundbreaking tool in revolutionizing Drug Delivery Systems (DDS), offering promising advancements in precision, efficiency, and personalized treatment strategies. The integration of AI technologies into pharmaceutical research and development is transforming how drugs are formulated, delivered, and monitored in real time. By leveraging machine learning algorithms and data analytics, researchers can design drug delivery models that are not only more effective but also tailored …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 48–61 Read article
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Sustainable Supply Chain Models for Polymer and Composite Manufacturing: A Data-Driven Assessment of Circular Material Flows
Abstract: Polymer and composite manufacturing is faced with growing demands in waste reduction, resource management, and making a shift towards circular economy principles. Although urgent, the adoption of data-driven tools in each step of a supply chain to facilitate efficient cyclic material flows is low. This paper designs and empirically analyzes sustainable supply chain design in polymer and composite production with a focus on digital traceability, closed-loop and material recovery, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 54–71 Read article
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Influence of Supplementary Cementitious Materials on Chemical Shrinkage in Cement
Abstract: Chemical shrinkage is the volume reduction observed in cement during early hydration due to chemical reactions, which critically influences the internal stresses, cracking tendencies, and durability of cementitious system. Present study is focused on effect of supplementary cementitious material (SCM) on chemical shrinkage. Dilatometry method is used to assess the impacts of SCMs on chemical shrinkage, in this this study. The research incorporates experiments with laboratory-synthesized cement and three SCMs—fly …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 98–107 Read article
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Examining the Relationship Between Academic Stress, Maladaptive Perfectionism and Trauma-Related Responses Among University Students
Abstract: Academic stress is a significant concern among university students, frequently contributing to maladaptive perfectionism and trauma-like responses. While perfectionism can enhance performance, its maladaptive variant may be exacerbated by academic stress which can induce trauma-like responses. This study investigates the correlation between academic stress, maladaptive perfectionism and trauma-like responses. Validated self-report measures were used in a quantitative, correlational study involving 101 university students. Linear regression analysis and Kendall’s Tau-B correlation …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 145–154 Read article
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Estimation of Alogliptin and Dapagliflozin in Synthetic Mixture by RP-HPLC Method
Abstract: The primary objective of the proposed research was to develop and validate analytical methods for the simultaneous quantification of Alogliptin and Dapagliflozin in a synthetic mixture. Alogliptin and Dapagliflozin are medications used for managing diabetes, with Alogliptin inhibiting the enzyme Dipeptidyl peptidase-4 and Dapagliflozin belonging to the class of sodium-glucose cotransporter 2 inhibitors. High-performance liquid chromatography method development was conducted using a C18 column (250 mmX4.6 mm, 5 μm particle …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 37–46 Read article
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Electromagnetic Transients in Compensated Power Lines- Revisited: New Approach and Case Studies
Abstract: This paper addresses the simulation of the electromagnetic transients developed in high voltage power lines, which are initiated by lightning discharges. The analysis can handle both individual and simultaneous series inductive and shunt capacitive compensation types. The sizes and locations of the compensating elements are included in the analysis. The derived Laplace s-domain mathematical model applies the concept of the ABCD transmission constants representing equivalent two-port networks. The resulting currents …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 2, Issue 1, 2024 · pp. 19–26 Read article
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Advancements in Method Development and Validation for Levocetirizine: A Comprehensive Review
Abstract: This review article delves into the intricate realm of concurrent estimation of multiple compounds, with a specific emphasis on Levocetirizine and its related substances. It looks into how to improve analytical process specificity by using reverse phase high-performance liquid chromatography (RP-HPLC) in conjunction with UV detection. The study meticulously explores the intricacies of method development and validation, offering invaluable insights into the realms of precision and accuracy within pharmaceutical analysis. …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 15–27 Read article
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Bio-Inspired FGPCs for Biomedical and Structural Applications
Abstract: Bio-inspired functionally graded polymer composites (FGPCs) represent a new class of smart materials that use gradient material distributions to enhance mechanical and biological properties, mimicking natural systems like bones, shells, and plant stems. FGPCs exhibit smooth gradient distributions across interfaces, which improves biocompatibility and reduces the risk of failure under complex loading and environmental conditions. In this study, bio-inspired FGPCs were designed, fabricated, and validated using a combined experimental and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 456–481 Read article
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AI-Driven Multi-Objective Optimization of Conductive Polymer Composites for High-Performance Flexible Electronics
Abstract: The development of conductive polymer composites (CPCs) is critical for advancing flexible and wearable electronic technologies. However, the conventional trial-and-error approach to material formulation is time-consuming and often inefficient due to the high-dimensional nature of the design space. This study introduces a novel AI-driven framework that integrates machine learning (ML) with multi-objective optimization to accelerate the discovery of high-performance CPCs. A dataset of 1,000 experimentally reported formulations was compiled, capturing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 734–745 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Review of Research on Pozzolanic Materials for Cement Blending and Concrete Applications
Abstract: The growing environmental concerns associated with cement production, particularly its high carbon footprint, have driven research into sustainable alternatives such as supplementary cementitious materials (SCMs) derived from agricultural and industrial waste. This study synthesizes findings from recent investigations into the pozzolanic potential of basil plant ash (BPA), rice husk ash (RHA), and stockpiled fly ash (FA), evaluating their processing methods, microstructural characteristics, and performance in concrete applications. BPA, being derived …
Published in Recent Trends in Civil Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 1–6 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article