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1966 articles for “H/D” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Targeting Homogentisate Dioxygenase Dysfunction in Alkaptonuria: Investigating Curcuma longa’s Therapeutic Potential
Abstract: Objectives: Alkaptonuria is known to have a faulty gene HGO in the metabolic process. In the present research work, the focus is towards investigating the therapeutic capabilities of the Curcuma longa upon the faulty Homogentisate dioxygenase gene using ligand-protein binding, which would assist in the corrective tyrosine metabolism. Methods: This study is based on the computational approach using different phytochemicals for evaluation of the potency against the abnormal Homogentisate dioxygenase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 1–11 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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Development and Assessment of a Nutraceutical Herbal Soft Drink
Abstract: The objective of this research was to develop and assess a nutraceutical herbal soft drink as a healthier alternative to conventional soft drinks, which have been scrutinized for their potential health risks due to high consumption rates. With an increasing number of individuals looking for healthier drink options, this study introduced a soft drink crafted from traditional herbs known for their nutritional benefits. The primary ingredients chosen for this soft …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 37–43 Read article
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Optimizing Heart Disease Prediction: Comparative Analysis of Machine Learning Algorithm for Early Detection
Abstract: The expanding realm of data analysis holds considerable importance in healthcare, particularly in the medical sector where forecasting heart disease is considered a complex endeavor. Early prediction of serious health conditions can be the determining factor between survival and fatality, with heart disease being one such critical health issue. Over the past decade, the main reason for death has been heart disease. Heart disorders come in many different forms, and …
Published in International Journal of Computer Science Languages · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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Bioenhancer to Boost Herbal Drug Efficacy
Abstract: Bioenhancers are natural substances that significantly improve the absorption, bioavailability, and therapeutic efficacy of drugs when co-administered, without showing notable pharmacological activity of their own. In herbal medicine, the concept of bioenhancement has received growing attention as many phytoconstituents exhibit low oral bioavailability due to poor solubility, limited permeability, and extensive first-pass metabolism. The traditional Ayurvedic system first introduced this concept through the discovery of Piperine, the active alkaloid from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Health and Air Quality in High-Density Neighbourhoods of Delhi
Abstract: Delhi, one of the fastest-growing megacities in the world, continues to grapple with critical challenges of urban air pollution and its direct consequences on public health. High-density neighborhoods like Karol Bagh, Lajpat Nagar, Chandni Chowk, and East Delhi face disproportionately higher exposure to degraded air quality due to compact urban forms, overcrowding, mixed land use, and heavy traffic. This paper explores the interrelationship between air quality and health outcomes, emphasizing …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 2, 2025 · pp. 26–32 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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Optimizing Heat Dissipation: Analysis of Air Cooled Fins for Electronic Equipments
Abstract: This paper focuses on the thermal management of electronic components in modern technologies like RADAR electronics, UAV and Drone technologies,Automotive Electronic Components etc. The main objective of this research is to design and develop an efficient heat dissipation system, using fins, for an electronic component with dimensions of 80 x 300 mm, dissipating 30W heat. The process starts by calculating essential parameters for fin design, followed by modeling the fins …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 3, 2025 · pp. 26–50 Read article
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Optimization of Pesticide Requirement Calculations for IoT-Operated Hexacopter Delivery Systems
Abstract: The integration of Internet of Things (IoT) technology into precision agriculture has transformed pesticide application strategies, enabling resource-efficient and environmentally sustainable practices. This study presents a computational methodology for optimizing pesticide requirements in an IoT-operated hexacopter system, designed for dynamic, data-driven pesticide delivery. Leveraging a fusion of real-time telemetric data from onboard LiDAR, multispectral imaging sensors, and environmental monitoring modules, the system employs predictive analytics and edge computing to calculate …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 08–14 Read article
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Association between Diabetes Type and Family History of Diabetes: A Cross-Sectional Analysis of Gender Differences and Genetic Influences
Abstract: Introduction: Diabetes mellitus DM is one of the fast-growing chronic metabolic disorder in the world, with high impact and burden in low- and middle-income country. Although genetic predisposition is a central determinant of diabetes risk, particularly for Type 2 diabetes (T2D), the contribution of familial aggregation varies across populations. In many parts of the world where diabetes is rising very fast understanding the relationship between diabetes type and family history …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 43–50 Read article
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Automated Healthcare Support System with AI
Abstract: The Automated Healthcare Support System with Artificial Intelligence (AI) presents a smart and scalable digital solution aimed at improving the accessibility and efficiency of healthcare services. The system is designed to provide preliminary medical guidance, perform symptom-based analysis, and deliver health-related insights through an intuitive user interface. By enabling early identification of potential health conditions, it assists users in determining the necessity of professional medical consultation. The proposed platform utilizes …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 Read article
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The Reaction About Anti-Hypertensive Drugs According to Plasma Renin-Aldosterone States
Abstract: With recent studies, hypertension has not only a simple pathophysiology, thus it can classify details more about and establishing drug therapy strategies compatible with it is a very important method to improve the organ predictive of patients. The purpose of this study is to compare the responsibility of some anti-hypertensive drugs in hypertensive patients according to plasma renin-aldosterone levels, which becomes the background factor of hypertension. We investigated 71 hypertensive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 14–23 Read article
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Comprehensive Perspective on Coronary Heart Disease: A Review
Abstract: The study explores intricate links between infections, inflammation, and coronary heart disease (CHD), emphasizing their multifaceted contributions to cardiovascular complications. It identifies infections as key players in atherosclerosis, a pivotal element in CHD development, with high antibody levels to specific pathogens as potential risk factors. The article highlights the role of the immune response and elevated C reactive protein (CRP) levels in amplifying infection-related CHD risks and recognizes smoking as …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 26–40 Read article
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Comparative Efficacy of Hybrid Capture 2 and Real-Time PCR in Detecting High-Risk HPV Genotypes for Cervical Cancer Screening
Abstract: Human papillomavirus (HPV) infection is a leading cause of cervical cancer, making early detection critical for effective prevention and treatment. Among the diagnostic methods available, Hybrid Capture 2 (HC2) and Real-Time Polymerase Chain Reaction (PCR) are widely used for detecting high-risk HPV genotypes, particularly HPV 16 and 18, which account for the majority of cervical cancer cases. This review aims to compare the efficacy of HC2 and Real-Time PCR in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 13–17 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Enhancing Chatter Resistance in Deep Hole Boring Through Modified Tool Design: A Study on Impact of Length-To-Diameter (L/D) Ratio
Abstract: Deep hole boring is a specialized machining process crucial for creating precise bores with high length-to-diameter (L/D) ratios, particularly vital in aerospace, automotive, and oil and gas industries. The L/D ratio is pivotal for stability and performance. Chatter, a detrimental vibration phenomenon, is a significant concern in deep hole boring, influenced by the L/D ratio. Higher L/D ratios increase chatter, leading to poor surface finish and reduced tool life. Longer …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 2, Issue 2, 2024 · pp. 24–33 Read article
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Lung Function Decline Among Brick Kiln Workers in Haryana Due to Chronic Particulate Matter Exposure
Abstract: In Haryana, India, brick kiln workers are subjected to high levels of Particulate Matter (PM) which has been shown to deteriorate respiratory health. This study looks into the effect sustained exposure to particulate pollution has on lung function among workers in the brick kilns. The objective of the study was to assess the impact of chronic exposure to particulate matter on lung function among brick kiln workers in Haryana. A …
Published in Journal of Industrial Safety Engineering · Vol. 12, Issue 2, 2025 · pp. 11–16 Read article
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Energy Savings due to passive strategies in contemporary high-rise residential building hot and dry climate
Abstract: Globally, the development of sustainable design techniques is becoming imperative, particularly with the idea of high-rise structures to keep up with the rapidly expanding cities. Approaching design sustainably by developing various sustainable methods is becoming necessary worldwide. Strategies for passive design may be useful in achieving the social, economic, and environmental goals of sustainability. This paper discusses the importance of passive design strategies in high-rise buildings, particularly in the context …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 99–103 Read article
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Contextualising health-disaster risk reduction pillars for under-resourced rural secondary schools in Limpopo Province, South Africa
Abstract: School communities in under-resourced rural settings face a disproportionate burden of health-related disasters, including outbreaks, water and sanitation failures, food insecurity and compound events that disrupt learning and wellbeing. Yet school based disaster risk reduction (DRR) evidence in Southern Africa is uneven with limited empirically guidance tailored to the organisational and infrastructural realities of disadvantaged schools. Drawing on the Comprehensive School Safety Framework and the World Health Organization's Health Emergency …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 124–135 Read article