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338 articles for “Cancer Cell”
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Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Harnessing Honeybee Venom For Cancer Treatment: A Natural Remedy In Oncology
Abstract: Honeybee venom (HBV) has harvested significant attention as a promising natural compound with therapeutic potential in cancer treatment. This review investigates deeply into the current scientific understanding of honeybee venom, focusing on its anticancer mechanisms, molecular interactions, and potential clinical applications. Honeybee venom comprises various bioactive components, including melittin, apamin, phospholipase A2, and other peptides, which exhibit a wide range of biological activities. Recent research has demonstrated its ability to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 10–14 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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Immunology and Immunotherapy of Pulmonary adenocarcinoma: A Systematic Review
Abstract: Lung cancer is the world's second leading cause of death, with an estimated 9.6 million deaths in 2018. Approximately 80% of all lung cancer is caused by non-small cell lung cancer (NSCLC). Due to lack of early detection and treatment, the incidence rate of lung cancer prognosis remains low. CD4+T-lymphocytes, macrophages, dendritic cells, and natural killer cells are among the immune cells involved in the pathogenesis of lung cancer. The …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 15–25 Read article
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Small Cell Neuroendocrine Carcinoma of Cervix: A Case Report and Review
Abstract: Cancer cervix ranks third of all cancers in the world. It remains a leading cause of cancer related death in the developing country. Various histologic subtypes seen in cancer cervix, squamous cell carcinoma (70%) is the most common one. Second common variety observed is adenocarcinoma which account for about 25% of cases. Other histologic subtypes are rare. Small cell neuroendocrine cervical carcinoma (SCNCC) is one of such uncommon variant that …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 2, 2016 · pp. 15–18 Read article
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In Silico Drug Designing of Breast Cancer in Homo sapiens
Abstract: Breast cancer is a severe health concern in India, with the highest mortality rate among women. It is brought on by uncontrolled cell division and has the potential to spread to other body regions. As a transcription factor, interactions with estrogen receptor (ER) alpha are primarily responsible for malignant tumors through regulating the transcription of numerous genes. Because most of the medications now used to treat breast cancer have significant …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 12–27 Read article
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Hematopoietic Stem Cells: Sources and Therapeutic Potential for Autoimmune Diseases and Cancer
Abstract: Hematopoietic stem cells (HSCs) are a group of multipotent adult stem cells that are responsible for lifelong production of all types of functional blood cells comprising myeloid (monocytes, macrophages, granulocytes), megakaryocytes/platelets, red blood cells (erythrocyte), T-cells, B-cells, natural killer (NK) cells, mast cells and dendritic cells (DCs). HSCs have the capacity for self-renewal and differentiation into various tissues. These remarkable properties of HSCs make them an ideal tool for tissue …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 3, 2012 · pp. 6–14 Read article
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A Review on Nano-emulsion for Delivery of Anti-cancer Drugs
Abstract: Cancer disease is characterized by abnormal cell growth. Malignant growth treatments have progressed significantly, yet there is a requirement for development in particularity and feeling of dread toward foundational harmfulness. Nanotechnology is the reconciliation of nanoscience into medication by the utilization of nanoparticles. The appearance of nanoscience in disease conclusion and treatment will assist clinicians with better surveying and oversee patients and further develop the medical care framework and administrations …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 7–13 Read article
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A Study on Cancer Related Fatigue and Quality of Life (QOL) among Women Undergoing Treatment for Various Cancers in Selected Tertiary Care Hospitals of Ludhiana, Punjab
Abstract: Cancer is a collection of illnesses marked by irregular cell proliferation that has the potential to infiltrate or metastasize to different areas of the body. Gynecological cancer specifically refers to the abnormal cell growth in the female reproductive tract, including various organs such as the endometrium, fallopian tubes, ovaries, uterus, cervix, vagina, and breast. These cancer cells have a tendency to multiply uncontrollably. The majority of individuals diagnosed with cancer …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 6–11 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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DETECTION OF LUNG CANCER USING SOFT COMPUTING TECHNIQUES
Abstract: Cancer is a generic term that can affect any part of the body. Most cancers, 90%-95%, are because by environmental and lifestyle variables which cause genetic mutations. Inherited genetics account for 5% to 10% of the total. Early identification of lung cancer has improved patient survival and has been a vital study topic. It starts within the cells covering the bronchi and lung parts like bronchioles or alveoli. Due to …
Published in Research and Reviews : A Journal of Immunology · Vol. 13, Issue 2, 2023 · pp. 1–12 Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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A Review on Natural Radio-protective Agents
Abstract: AbstractRadioprotectors play crucial role in safeguarding biological system from various damages to DNA (Deoxyribonucleic acid), protein molecules, lipids by peroxidation as well as hematopoietic, gastrointestinal, reproductive and central nervous system exposed to radiation dose especially against radiation injury in cancer survival patients undergoing radiotherapy. As over 40% patients require this therapy, during the treatment where ionizing radiation is used to shrivel tumors and exterminate cancer cells by disrupting their DNA. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 20–31 Read article
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Emerging Engineered Nanoweapons for Tumors
Abstract: Cancer is a type of disease characterized by abnormal growth of cells which tend to proliferate in uncontrolled manner. It occurs at molecular level when genes undergo genetic alterations. The malignant growth of tumor cells results in non-functioning of the concerned organ. Over the years, cancer targeting technique has greatly improved by new approaches based on nanotechnology. Nanotechnology is helpful in development of new therapies against cancer. Nanotechnology is a …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 1–6 Read article
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Piezoelectric Nanoparticles Loaded with Curcumin for Cancer Treatment
Abstract: Conventional cancer chemotherapy treatments are often compromised by systemic toxicity which starts from the lack of tumor specificity of administered anticancer drugs. The side effects limit the dose of the drug that can be administrated, making effective cancer treatment difficult. Nanoparticle-based drug delivery has the potential to overcome this challenge by targeted delivery to tumor and taking the advantage of tumor’s natural leaky vasculature to increase the accumulation of drug-loaded …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 6, Issue 2, 2016 · pp. 1–6 Read article
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Morinda citrifolia Leaf Induced Leukemia Cells Apoptosis and Produced Synergistic Effects with Zerumbone
Abstract: Leukemia is the most common cancer among children and the 7th most common cancer worldwide. The vegetable Morinda citrifolia leaves was investigated and compared with Zerumbone (a known anti-leukemia compound) separately and in combination, for their apoptotic effects on murine myelomonocytic leukaemia cell line (WEHI-3B). Zerumbone, a sesquiterpene from Zingiber zerumbet was anti-cancer via suppressing free radical generation, inflammation, cancer cell proliferation, metastasis, anti-apoptosis, NF-κβ, Iκβα kinase activation and invasion. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 24–32 Read article
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Iota carrageenan, a Sustainable polymer transformed into a nanogel formulation, by using environment friendly method for antitumor action
Abstract: In the pharmaceutical field, the utilization of polymers, both in their natural form and through chemical modifications, holds immense importance. In this context, a novel and eco-friendly method for the synthesis of nano carrageenan-based polymers has been developed. The efficacy of carrageenan in this domain is attributed to its crosslinking and biological properties, which are largely influenced by its sulfate ion content. This study aims to formulate nanogels via a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 881–889 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Medicinal Chemistry of Nanoparticles for Cancer Theranostics
Abstract: Cancer is a disease in which cells growth is uncontrollable and conventional treatment have a few side effects, for example, nonspecific delivery, unable to enter the center of tumor and absence of solubility. Nanoparticles could directly target disease cells specifically and increased medication localization in tumor cells giving exact cellular uptake. The theranostic nanomedicine can accomplish systemic flow, avoid host resistances and deliver the medication and diagnostic agents at the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 3, 2016 · pp. 28–41 Read article