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1670 articles for “demonstration”
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Current-Voltage Characteristics of 15-Atom Agnrs and Zcnts at Various Bias Voltages: Insights for Polymer Nanocomposite Applications
Abstract: The present research investigates the electronic properties of 15-atom Armchair Graphene Nanoribbons (AGNRs) and 15-atom Zig-Zag Carbon Nanotubes (ZCNTs) under applied bias voltages of 100, 200, 300, 400, 500, and 600 millivolts. Using the Non-Equilibrium Green's Function (NEGF) technique, the study analyzes various electrical features, including current-voltage (I-V) characteristics, to understand the behavior of these nanostructures. The findings reveal that AGNRs exhibit a larger bandgap than ZCNTs, which have a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 135–144 Read article
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Deep Learning -Based Dental Issue Detection
Abstract: Dentistry is vital for preserving oral health, a key component of overall wellness. Early identification of dental issues is crucial for effective treatment and avoiding further complications. Conventional approaches to diagnosing dental problems typically depend on physical examinations and visual assessments by skilled professionals, which can be both time-intensive and influenced by individual judgment.In recent years, the application of deep learning algorithms has demonstrated significant potential in automating and enhancing …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 18–23 Read article
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Enhancing Building Energy Efficiency Through IoT Integration
Abstract: Building management systems featuring Internet of Things (IoT) technology provide a revolutionary way of maximizing user comfort and improve the use of energy. This study presents a comprehensive analysis of various components within an IoT subsystem utilized in building management, including Smart IoT Gateways, temperature and humidity sensors, lightweight database systems such as Tiny DB, and cloud communication platforms like Twilio. Each component plays a vital role in facilitating real- …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 2, Issue 2, 2024 · pp. 15–23 Read article
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Self-Healing Thin Films: Paving the Way for Smart, and Sustainable Corrosion Protection
Abstract: Corrosion is one of the serious problems that industries and infrastructures of every type face, ranked among such threats as huge economic losses and concerns to global safety. Recent developments in the area of self-healing thin films make them a really promising innovation for enhancing corrosion protection. This review considers the development, mechanisms, and applications of self-healing thin films. Detailed here are intrinsic and extrinsic self-healing strategies oriented toward chemical …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 22–45 Read article
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Design and Implementation of an IoT-based Traffic and Parking Management System Integrated with GIS for Urban Environments
Abstract: As urbanization accelerates, managing traffic flow and parking availability has become increasingly challenging. This article presents the design and implementation of an internet of things (IoT)-based traffic and parking management system integrated with geographic information systems (GIS) to address these challenges in urban environments. The proposed system utilizes a network of IoT sensors to monitor traffic flow, congestion levels, and parking space availability in real time. The data collected by …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 23–32 Read article
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Correlation Analysis of Gastrocnemius Tightness and Heel Pain Severity: A Study on Plantar Fasciitis
Abstract: Background: Plantar fasciitis, a common source of heel pain, is frequently linked to tightness in the gastrocnemius (GCN) muscle. This study seeks to examine the relationship between GCN tightness and the severity of heel pain in plantar fasciitis patients over time, investigating the potential role of muscle flexibility in alleviating pain. Methods: A prospective cohort study was conducted with 74 patients aged 25–65 diagnosed with P. fasciitis at Santosh Hospital, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 57–64 Read article
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Enhancing Bituminous Mixes with Recycled Polyethylene: Performance Analysis Using Marshall Stability Test
Abstract: This study investigates the impact of incorporating recycled low-density polyethylene (LDPE) and high-density polyethylene (HDPE) in bituminous mixes for potential use in flexible pavement construction. Utilizing a Marshall Stability Test, various proportions of LDPE and HDPE were analyzed to determine optimal stability and flow characteristics. The test maintained a fixed Zycotherm content at 1.5% and varied LDPE content from 2% to 5% by weight, while HDPE content was also tested …
Published in Recent Trends in Civil Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 1–5 Read article
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Unveiling Patterns in Complexity: The Role of Simple Statistics and Fuzzy Mathematics in Data Analysis
Abstract: In this study, statistical methods must be integrated with fuzzy mathematics to solve complex data. Statistical methods offer clear, unbiased, and computationally feasible tools for analysing numerical data. whereas fuzzy mathematics excels in describing the vagueness and ambiguity of human feeling by way of linguistic variables, membership functions, and inference systems. Giving it an apparent advantage when modelling complex conditions. Hybrid frameworks offer fine-grained decision-making and resilient adaptability to real-world …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 1, 2025 · pp. 01–10 Read article
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Mathematical Models of Agricultural Cycles in Tribal Astronomy
Abstract: This paper delves into the intricate connection between traditional tribal agricultural practices and astronomical observations, showcasing how indigenous communities have historically relied on celestial movements to guide essential farming activities. By observing the phases of the moon, solar cycles, and the positions of star constellations, tribes have developed precise methods for determining the optimal timing for planting, harvesting, and seasonal planning. These astronomical practices are deeply embedded in their cultural …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Comprehensive study of Entanglement Entropy in Quantum Field Theory: Analysis of Conformal Field Theory to Massive Field Extensions and Holographic Entanglement
Abstract: This paper provides an in-depth analysis of entanglement entropy (EE) in quantum field theory (QFT), with a particular focus on its computation using the replica trick and its applications to both conformal and non-conformal systems. Beginning with an introduction to the basics of QFT, the study explains how entanglement entropy quantifies the quantum correlations between subsystems in a pure state, represented by the von Neumann entropy of the reduced density …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 3, 2024 · pp. 33–58 Read article
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Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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A Polymer-Based Recommender System for Precision Agriculture: Enhancing Crop Yield Analysis Using IoT Technology
Abstract: This study introduces an innovative recommender system that employs polymer-based sensors combined with advanced data analytics to deliver personalized recommendations for crop management optimization. The use of polymer-based materials in sensor design allows for the creation of durable, cost-effective, and efficient sensors, well-suited for the challenging conditions typical in agricultural environments. These sensors are designed to withstand variations in numerous factors like temperature of the surrounding, humidity level, and at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 86–95 Read article
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Smart Protective System for EVs
Abstract: Electric vehicles, or EVs, form the bedrock of sustainable transportation, offering both energy efficiency and low carbon emissions. However, the safety issues emanating from the complexity of road conditions call for innovative solutions. This paper introduces a Smart Protective System for EVs, integrating YOLOv5 for real-time obstacle and pothole detection with ultrasonic sensors for proximity measurement. The system is able to achieve an object detection accuracy of 95% under normal …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 8–14 Read article
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Voltage Vigilance: Ensuring Balance and curbing Theft in Power Distribution Networks
Abstract: This project proposes a system for detecting electrical overload and earth faults using an Arduino Uno controller. The system uses a current sensor to identify overloads and a voltage sensor to detect earth faults. An ESP8266 module allows users to switch between the two fault detection modes. When an overload is detected, the Arduino turns off AC bulbs using a relay and sends an alert message via a GSM module. …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 15–21 Read article
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Role Of Autologous Platelet-Rich Plasma (APRP) In Take of Graft
Abstract: Autologous platelet-rich plasma (APRP) has gained attention as a promising adjunct in skin grafting procedures, particularly in enhancing the take and healing of grafts in burn patients. This study focuses on the application of APRP to improve the adherence of split-thickness skin grafts (STSG) in a pediatric patient with scald burns. APRP is prepared by concentrating the patient’s platelets from a small volume of blood, which is rich in growth …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 · pp. 1–5 Read article
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Characterization of Nano-Clay Reinforced Polymer Composites: Enhancing Performance for Extreme Applications
Abstract: This study investigates the mechanical, thermal, water absorption, and chemical resistance properties of nano-clay-reinforced polymer composites and polymer concrete. The incorporation of 1-5 wt% nano-clay resulted in a significant enhancement across all properties. Mechanical testing revealed a 42.86% increase in tensile strength (35 MPa to 50 MPa), 40% improvement in flexural strength (50 MPa to 70 MPa), and 46.67% rise in compressive strength (75 MPa to 110 MPa), attributed to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 105–114 Read article
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Enhancing Mechanical Properties by Parameter Optimization in Fiber and Particle Reinforced Composites
Abstract: This research focuses on optimizing the mechanical and thermal properties of hybrid fiber and particle-reinforced composites through systematic parameter optimization using the Taguchi method and Grey Relational Analysis (GRA). Composites were fabricated using varying fiber volume fractions (20%, 30%, and 40%), particle sizes (20 μm, 60 μm, and 100 μm), and curing temperatures (60°C, 80°C, and 100°C) in a 3-factor, 3-level experimental design. Key properties such as tensile strength, impact …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 75–85 Read article