Search
267 articles for “physical and chemical property”
-
Ligand Efficiency in Relation to 3D Physicochemical Characters of Novel HIV-1 Vif Antagonist: An Approach in The Optimization of HIV Drugs
Abstract: AbstractLigand efficiency is a design framework commonly used in drug discovery. Thirty-six (36) newly discovered 1,2,3-triazole analogues as potent new inhibitors of HIV-1 Vif were subjected to quantitative structure-property relationship (QSPR) modeling to predict their ligand efficiencies (LE) in an attempt to improve/optimize it by using some numerical data of HIV-1 Vif inhibitors based on their physical and chemical properties (descriptors). Various 3D physicochemical properties or descriptors were calculated from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 50–59 Read article
-
Drug-likeness and 3D-QSAR Analysis of 1,2,3-triazoles as Novel Potent HIV-1 Vif Inhibitors: An approach in the development of Leads in the Treatment of HIV Infection
Abstract: AbstractThe human immunodeficiency virus type 1 (HIV-1) Vif protein is one of various primate lentiviral accessory proteins that act as a virulence factor to advance viral duplication and persistence. 3D quantitative structure-activity relationship (QSAR) modeling of thirty-six (36) newly discovered 1,2,3-triazole analogs as potent novel inhibitors of HIV-1 Vif to predict their biological activity (pIC50), to try to improve/optimize it using some numerical data of HIV-1 Vif inhibitors based on …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 3, 2022 · pp. 23–37 Read article
-
Corrosion Testing and Evaluation of Inhibitors Performance
Abstract: Choosing test methods that will analyze specific needs, like film barrier strength that real field settings is essential for the proper evaluation and development of inhibitors. The flowing loop and the bubble test are two examples of the first and second, respectively. Corrosion is measured by gravimetric, electrical noise, alternating-current impedance, potentiodynamic measurement, linear polarization and gravimetric. The inhibitors action can be analyzed in different corrosive environments. Their performance is …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 82–88 Read article
-
Synthesis and Characterization of Size Tuned CdS Quantum Dots
Abstract: CdS nanoparticles are synthesized using chemical precipitation at room temperature. Cadmium sulfide is one of the most promising materials for solar cells and of great interest for their practical applications in up to electronics and photonics. The optical properties get modified due to the confinement of charge carrier within the nanoparticles. The physical and chemical properties of these nanoparticles are found to be size dependent. The crystallite sizes of cadmium …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 8, Issue 1, 2018 · pp. 28–39 Read article
-
A Concise Overview of Recent Developments and Uses in Nano-Silica and Nanoparticles Encased in Silica
Abstract: Nano-silica and silica-coated nanoparticles have gained significant attention lately due to their exceptional chemical and physical properties, including a high surface area-to-volume ratio, adjustable porosity, thermal and chemical stability, biocompatibility, and ease of surface modification. These characteristics make them versatile materials applicable in various scientific and industrial sectors. Their ability to control particle size, shape, and surface traits allows them to be effectively utilized in catalysis, drug delivery, biosensing, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 696–704 Read article
-
ROLE OF SHODHANA KARMA IN IMPROVING EFFICACY OF RASA DRAVYA
Abstract: Shodhana which literally means purification and converting drugs suitable for further procedure. Shodhana is procedure necessary for every drug before taking it for pharmaceutical and therapeutically purposes. The aim of Shodhana is to remove the physical and chemical properties in the sample of raw drugs. Shodhana is also meant for Marana process of minerals and metals for further internal uses. Shodhana is a process which not only eliminates physical and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2018 · pp. 33–36 Read article
-
Development Healthy Drink Use of Orange Juice, Carrot Juice, Aloe vera Juice, Holy Basil Dry Leaves Powder
Abstract: The phytochemical and physiochemical properties of orange juice enriched with carrot juice aloe Vera juice and whole besil dry leafs powder in this study the physic chemical and properties phytochemical properties of 70% orange juice 15% carrot juice 10% aloe vera juice 5% basil dry leafs extract powder were studies is healthy drink with high content of vitamin C zero fat due to which our drinks considered as healthy drink …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 6, Issue 3, 2017 · pp. 38–53 Read article
-
Quality Assessment of Underground Water in Summer Season of Rewa City, Madhya Pradesh, India
Abstract: This paper presents the quality assessment of underground water and seasonal variation in physical and chemical properties of underground water in a summer season of Rewa district, Madhya Pradesh state, India. The variable data of samples are within prescribed limits as suggested by the world health organization (WHO), Indian standard (ISI) and BIS desirable limit for drinking water for drinking purpose. Yearly variation in physical and chemical parameters like temperature, …
Published in Journal of Water Resource Engineering and Management · Vol. 3, Issue 1, 2016 · pp. 34–41 Read article
-
Demonstrative Research of Group VII Elements of the Periodic Table: Characteristics and Properties of Chemical Behavior
Abstract: The elements in Group VII, commonly referred to as halogens, are non-metals that exhibit similar chemical characteristics and a high level of reactivity, which can be attributed to their electron configuration. This paper seeks to provide an overview of the relationship between the electron structure and chemical behavior of the Group VII elements found in the periodic table. The primary goals include elucidating how the electron configuration influences the physical …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 2, 2025 · pp. 18–26 Read article
-
Innovative Approaches in Excipient Co-Processing: A Comprehensive Review
Abstract: Co-processing of existing excipients is an innovative strategy in pharmaceutical formulation that offers a cost-effective, efficient alternative to the development of entirely new excipients. This process involves combining two or more well-established excipients to create new material with enhanced properties, thereby improving the functionality, performance, and manufacturability of pharmaceutical products. By leveraging the unique characteristics of each excipient, co-processing can significantly enhance attributes, such as flowability, compressibility, solubility, stability, and …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 34–51 Read article
-
Preliminary Investigation on Steel Slag: Production, Processing and Cementitious Properties
Abstract: Steel slag is glass-like by-product left over from the conversion of iron to steel in a basic oxygen furnace, or from the melting of scrap to make steel in an electric arc furnace. This paper reviews the production, processing, and cementitious properties of steel slag, and its use as a cementing component in different cementing systems. The chemical composition of raw ore and cooling of molten steel slag have a …
Published in Recent Trends in Civil Engineering & Technology · Vol. 6, Issue 2, 2016 · pp. 17–22 Read article
-
Formulation and Development of Soft Chewable Palm Tree Jaggery Based Cough Lozenges
Abstract: Lozenges are used for treatment of relief from severe cough, Phargnitis, throat infections, and the common cold. Comparative studies were carried of the herbal lozenges with two different sweetening agents, jaggery and crystal sugar. Herbal Lozenges were prepared using Aloe vera gel, pepper powder, dry ginger powder, clove powder, dried powder of tulasi, mint leaves, Liquorice powder and turmeric as major medicament and palm tree jaggery or crystal sugar served …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 3, 2022 · pp. 47–52 Read article
-
Chemical Composition and Antimicrobial Efficacy of Ferula persica Extracts: A Phytochemical and Bioactivity Assessment in Iraq
Abstract: The research presented in the tables focuses on analyzing the chemical content of extracts from the Ferula persica plant, a wild species in Iraq with significant medical and therapeutic importance dating back to ancient times. This study involved testing some chemical and physical properties of the alcoholic extract of the plant's aerial parts and evaluating its antimicrobial activity, specifically against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). The …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 10–22 Read article
-
Physicochemical Analysis of Kollidam River, Tamil Nadu, India
Abstract: The present study was conducted in the time period of one year (January 2011–December 2011) with an aim to find out the physicochemical nature of water at three different sites of Kollidam River in order to analysis the physical properties and chemical nature of its water and the impact of sites on their concentration. Three sites were selected for the study purpose and the samples were collected on monthly basis. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 1, 2018 · pp. 11–15 Read article
-
A Review on Mechanical and Tribological Properties of Metal Matrix Composites
Abstract: AbstractNowadays, there is a rapid development in advanced metal matrix composites for structural engineering and functional devices. A real change in research from monolithic to composite materials has taken place due to need for low cost, high performance and good quality materials from the past decade. Composite materials consist of two or more materials that may differ in chemical and physical properties and are not soluble in one another. The …
Published in Journal of Polymer & Composites · Vol. 4, Issue 1, 2016 · pp. 16–26 Read article
-
Minerals: A Comprehensive Review of Classification, Properties, Formation, and Their Role in Modern Technology and Sustainability
Abstract: Minerals are naturally occurring, inorganic, solid elements with a definite chemical composition and a characteristic crystal structure. They are the building blocks of rocks. Minerals are the key to the development and progress of human civilization. They are used for the development of infrastructure, electronic gadgets, agriculture, and medicine. This research paper aims to present an exhaustive overview on the field of mineralogy, which includes the definition, classification, physical and …
Published in International Journal of Crystalline Materials · Vol. 3, Issue 1, 2026 · pp. 25–33 Read article
-
Comparison between Some Physical and Chemical Proprieties of the Water in Khartoum Sites
Abstract: Water is a life source it cover most of the earth surface, it can be found in rivers, seas, oceans and ground water. It may has different proprieties depend on the sources or seasonal or the environments. In this study measurements of some physical and chemical variables were made specifically in Khartoum site, where water samples were taken from different areas representing rivers, wells and water purification stations. Then UV …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 8, Issue 1, 2019 · pp. 13–21 Read article
-
Advancements in Solubility Enhancement Through Liquisolid Compact Technology: A Comprehensive Review
Abstract: The study examines Liquisolid Compact Technology as an innovative approach for improving the bioavailability and solubility of drugs that are poorly soluble in water. Liquisolid systems, comprising solid carriers and liquid drugs, offer advantages such as improved drug release and bioavailability, reduced manufacturing costs, and controlled drug delivery. The technique involves dissolving or suspending the drug in non-volatile solvents, adding carrier materials, super disintegrants, and coating materials, and then compressing …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 25–34 Read article
-
Formulation and Evaluation of Saliva Substitute
Abstract: The development and evaluation of saliva substitutes play a vital role in managing xerostomia, a condition marked by insufficient saliva production that adversely affects oral health and overall well-being. This study investigates various formulations of saliva substitutes intended to replicate the functionality of natural saliva. The key goals are to assess their moisturizing effectiveness, physical and chemical properties, and in vitro performance. These formulations generally incorporate hydrators, lubricants, thickeners, and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 32–47 Read article
-
Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article