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63 articles for “organ dose”
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Histological Alteration in the Kidney of a Fresh Water Cat Fish Clarias Batrachus Exposed to Silver Nanoparticles
Abstract: Despite increasing application of silver nanoparticles (NPs) in industry and consumer products, there is still little known about their potential toxicity, particularly to organism in aquatic environment. Our aim is to investigate the fate and effect of silver NPs in fish Clarias batrachus. The histological alterations in the kidney of a freshwater catfish Clarias batrachus exposed to sublethal concentration silver nanoparticle were examined. The kidney exhibited shrinkage of glomeruli but …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 2, 2019 · pp. 1–8 Read article
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Evaluation on the Sensitivity of the Freshwater Tropical Worm, Branchiura sowerbyi (Beddard, 1892) to the Pyrethroid Pesticide, Bifenthrin
Abstract: In the present study, acute toxicity of the pyrethroid pesticide, bifenthrin, was evaluated under the experimental condition to the freshwater tropical oligochaete worm, Branchiura sowerbyi. The 96 h LC50 with 95% confidence limits of B. sowerbyi was 1.043(0.721-1.327) μg/l. None of the unexposed control test animal died during the experiment. Relation between each concentration and mortality rate during 24–96 h was found to be correlated. The mortality rate varied significantly …
Published in Research & Reviews : Journal of Ecology · Vol. 9, Issue 1, 2020 · pp. 8–13 Read article
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New Drug Approvals and Prohibition during the Mid-Year of 2016
Abstract: Every day drugs are being approved by various drug controlling authorities, for treating ailments and for improvising health care. USFDA, CDER and CDSCO (Central Drugs Standard Control Organization) play major role in controlling the drug usage in India, to ensure the safety and efficacy of the treatments. In India most of the OTC products has been banned and this review helps in simplifying the list of the drugs banned and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 1, 2017 · pp. 22–25 Read article
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Role of Radiation Therapy in the Management of Mycosis Fungoides
Abstract: Cutaneous T-cell lymphoma (CTCL) consists of spectrum of diseases of which Mycosis Fungoides and Sézary's syndrome are most common. Mycosis Fungoides (MF) is a low-grade, chronic lymphoproliferative disorder affecting skin caused by abnormal proliferation of CD4 + T-cells. The incidence of MF is showing an increasing trend all over the world. Also, it is seen twice as often in males as in females (2:1) and mostly it occurs after fourth …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 1, 2012 · pp. 6–15 Read article
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Removal of Cadmium from Aqueous Solution by Modified Sawdust as Adsorbent
Abstract: The study was carried out to determine the percentage removal efficiency of heavy metal like cadmium by using the modified form of sawdust as an adsorbent. Cadmium is highly toxic to human, plant and all living organism present in the environment. It was found that the chemically treated sawdust is a better adsorbent as compare to the untreated form of sawdust. After treating the sawdust with sodium hydroxide (NaOH), it …
Published in Emerging Trends in Chemical Engineering · Vol. 2, Issue 2, 2015 · pp. 22–24 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Homeopathic Posology: Principles and Practice
Abstract: The cornerstone of homeopathy lies in the principle of individualized therapy, and this concept is equally significant in determining the posology of homeopathic medicines. Unlike conventional medicine, where dosage is often standardized, homeopathic posology is carefully adapted to the specific condition and overall state of the patient. The primary source of guidance for homeopathic prescribing is Hahnemann’s Organon of Medicine, a seminal work published in six successive editions, each reflecting …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 52–58 Read article
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Impact of a Structured Educational Program on Awareness of the Human Papilloma Virus Vaccine for Cervical Cancer Prevention Among Women in a Chosen Rural Region of Rajkot
Abstract: The World Health Organization (WHO) advocates for the inclusion of the human papilloma virus (HPV) vaccine in standard immunization schedules worldwide, in addition to other preventive strategies. The launch of the prophylactic HPV vaccine has markedly improved primary prevention measures against cervical cancer and other diseases caused by HPV. Following their approval in 2006, both the quadrivalent and bivalent HPV vaccines have received authorization in over 100 countries. As of …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 18–22 Read article
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Ocular Drug Delivery System: Challenges and Opportunities
Abstract: Eye is most sensitive organ of body which is highly protected to prevent entry of any exogenous substance. This defence mechanism of eye renders the development of ocular drug delivery system as the challenging task to ophthalmic formulation scientist. Knowledge of anatomy, physiology and barriers for transportation of drug at different target site of eye is essential to develop successful ocular formulation. Topical administration of drug in the form of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 3, 2018 · pp. 14–30 Read article
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Prescribing Patterns of Analgesics in Surgical Departments in a Tertiary Care Hospital
Abstract: Analgesics are routinely employed in the management of pain in surgical departments. Drug utilization studies evaluate the present trends of drug usage, drug expenditures, appropriateness of prescriptions and adherence to evidence-based recommendations. The Objectives were to study the prescribing pattern, approval status, inclusion in World Health Organization (WHO) essential medicines list/National List of Essential Medicines (NLEM), cost and rationality of analgesics prescribed in surgical departments. Data were collected from records …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 9–16 Read article
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Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article
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Recombinant Insulin
Abstract: Recombinant insulin, a revolutionary product of biotechnology, has transformed the landscape of diabetes treatment. Developed through genetic engineering techniques, recombinant insulin offers a safer, more consistent alternative to traditional animal-derived insulin. Its production involves the insertion of the human insulin gene into host organisms such as Escherichia coli or Saccharomyces cerevisiae, which serve as efficient factories for insulin synthesis. Recombinant insulin is used to treat diabetic patients who are allergic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 39–43 Read article
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Using Nuclear Grade Resin for Ion exchange
Abstract: In EDF, especially in the nuclear business, ion exchange resins are regularly employed for water purification. High-quality nuclear grade resins must be used in primary and secondary circuits as well as effluent treatment to retain dissolved species, some of which may be radioactive. To decrease worker dose during maintenance and to reduce radioactive resin waste volumes, purification needs to become more and more effective. The right resin qualities must be …
Published in Journal of Nuclear Engineering & Technology · Vol. 11, Issue 3, 2021 · pp. 33–37 Read article
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Uranium Content Anomalies in Groundwater of Patiala District of Punjab (India) for the Assessment of Excess Cancer Risk
Abstract: Inductively coupled plasma mass spectroscopy (ICPMS) has been used to measure the uranium content of ground water samples of Patiala district of Punjab (India). Out of total 810 habitations covered under this survey, 94 were having uranium content equal or more than 30 ppb (safe limit of the World Health Organization). The aim of this study was to investigate the uranium content of groundwater in the Patiala district of Punjab …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 13–19 Read article
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Microbial Contaminants in Commercial Beverages: Health Concerns and Suggestive Preservative Methods
Abstract: AbstractFruit juices are the important source of vitamins, minerals and antioxidants, essential for the growth and development of every human. However, due to the presence of various nutritive components, it provides optimal conditions for the growth of food microorganisms. Various pathogenic and non-pathogenic bacteria, fungus, yeasts and parasites are found to be associated with fruit juices. Many of these microbes generally enters at the time of packaging and cause various …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 1–10 Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Antidiabetic Potential of Bryophyllum pinnatum: A Study on its Pharmacological Effects and Synergistic Action with Glibenclamide
Abstract: Diabetes is a long-term metabolic disorder that profoundly impacts an individual’s overall health, social interactions, and quality of life. While significant progress has been made in diabetes management with the use of medications such as insulin and oral hypoglycemic agents, the limitations of these existing treatments highlight the need for new therapeutic alternatives. Moreover, the high cost of current diabetes medications makes them inaccessible to many, particularly in rural areas …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 18–30 Read article
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A Study to assess Prescription pattern in outpatient department of tertiary care hospital
Abstract: ABSTRACTBackground:Antibiotic resistance and irrational prescribing is a global concern, is particularly pressing in developing nations, including India, where the burden of infectious disease is high and healthcare spending is low. The Global Antibiotic Resistance Partnership (GARP) was established to develop actionable policy recommendations specifically relevant to low- and middle-income countries where suboptimal access to antibiotics - not a major concern in high-income countries - is possibly as severe a problem …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 2, 2018 · pp. 33–36 Read article
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A Review on Drug Delivery Systems Using Microfluidics
Abstract: AbstractMicrofluidics is undoubtedly an influential technology that is currently revolutionizing the chemical and biological studies by replicating laboratory benchtop technology on a miniature chip-scale device. In the area of drug delivery science, microfluidics offers advantages, such as accurate dosage, ideal delivery, target-precise delivery, sustainable and controlled release, several dosing, and slight side effects. These helps bring significant assets to the drug delivery systems. Microfluidic technology has been increasingly used for …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 10, Issue 1, 2020 · pp. 1–10 Read article
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Saccharomyces Cerevisiae and Pichia Pastoris Optimize NH4NO3 by 50 % in Solanum Lycopersicum Preventing N2O Release.
Abstract: In agriculture, the unregulated application of NH4NO3 for healthy growth of Solanum lycopersicum is associated in the soil with the denitrification of free NO3- (nitrate), with an increase in N2O, a greenhouse gas, that contributes to global warming, loss of soil fertility. An ecological option to avoid denitrification that releases N2O as other environmental problems is to inoculate S. lycopersicum seeds with endophytic yeasts that promote plant growth, such as …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 7–13 Read article