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166 articles for “markers”
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Breeding and Genetics of Disease Resistance in Poultry and Farm Animals: A Review
Abstract: Disease resistance is one of the most essential parameters that is now getting consideration in the animal selection along with production traits. Development and rearing of genetically disease resistant stocks is the newer face of animal husbandry at present. The increasing microbial resistance, increased drug residues in animal products, ever increasing cost of therapeutic treatment, and consumer’s preference towards organic products are all giving bright signal to the development of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 10, Issue 1, 2021 · pp. 1–7 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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ADVANCEMENTS AND CHALLENGES OF MODERN BREEDING OVER CONVENTIONAL BREEDING
Abstract: Plant breeding dates back thousands of years, when people first deliberately bred plants based on visually pleasing characteristics. The domestication of wild plants aided this process, resulting in the evolution of numerous breeding strategies over time. Conventional breeding, which is distinguished by selective breeding based on superior performance, used procedures such as pure-line selections, mass selection, backcross breeding, recurrent selection, and hybridization. While effective, classical breeding procedures were time-consuming and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–5 Read article
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Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 · pp. 10–19 Read article
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Progress from the Traditional Vaccines to Novel Rational Vaccine Designs
Abstract: Vaccines are among the most valuable assets for saving human and animal lives. The vaccines discovered and designed on the Pasteurian principles laid the foundations of the traditional vaccine regime during the late-19th century. Some traditional vaccine designs proved remarkably successful, while others had safety or efficacy problems, and still others failed- particularly those against diseases caused by non-cultivable, hyper-variable or opportunist pathogens, or those requiring cellular immunity. The problems …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 17–31 Read article
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Endosulfan-Induced Hepatotoxicity and its Amelioration by Administration of Bamboo (Dendrocalamus Strictus) Seed Extract in Rats
Abstract: Endosulfan is an important hepatotoxic agent that generates free oxygen radicals in liver and the incidence of toxic injury to the liver tissue in relation to its widespread has been reported. Bamboo is rich in phenolic components which possess various bioactivities and bamboo seed extract was found to have antioxidative properties. Hence, the present study has been designed to assess the protective role of bamboo seed extract against endosulfan induced …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
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Estimation of Genetic Diversity in Some Species of Meliaceae Family through RAPD Technique
Abstract: Random amplified polymorphic DNA (RAPD) analysis has proved to be useful in determining genetic relationship and variation in many plant species, result of RAPD analysis can be used to determine genetic distances and relatedness within or among species, which can then be utilized in construction of phytogenetic. RAPD analysis could also provide useful insights into the phylogenetic relationship. RAPD is a polymerase chain reaction (PCR), which is based on dominant …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 3, 2015 · pp. 11–17 Read article
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Conventional and Molecular Breeding for Bacterial Leaf Blight and Blast Resistance in Rice
Abstract: AbstractBacterial leaf blight (BLB) and blast are the major limiting factors for rice production in the world. Host resistance mechanism by exploiting the resistance genes (R gene) is one of the most effective ways to achieve the genetic potential of the rice cultivars. Conventional breeding in the past has developed several resistant varieties having major genes for resistance to blast and BLB. Marker-assisted backcross breeding (MABB) provides a long way …
Published in Research & Reviews : Journal of Ecology · Vol. 3, Issue 3, 2014 · pp. 1–3 Read article
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Iron Profile in Gestational Diabetes Mellitus
Abstract: Background: The precise mechanisms behind the etio-pathogenesis of gestational diabetes mellitus (GDM) are unknown. According to epidemiological evidence, GDM is linked to higher body iron reserves. Higher serum ferritin levels, which are widely employed as a marker of the body's iron store, have been observed in people with diabetes mellitus. The goal of this study was to see if this occurred in GDM women. Materials and Methods: From April 2023 …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 20–24 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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A research study into the interactions between the monoherbal formulations of arjuna and Aloe vera in a rat model of isoproterenol-induced cardiotoxicity
Abstract: Aloe vera is a herbal dietary supplement, and arjuna is used for its cardioprotective properties. Rats were given isoproterenol hydrochloride subcutaneously to cause myocardial infarction. The purpose of the study was to identify any potential pharmacodynamic interactions between the commercially available formulations of Aloe vera and arjuna. Materials and Procedures: The electrocardiogram (heart rate, ST segment elevation time, QRS complex amplitude), serum cardiac markers (creatine kinase, isoform of creatine kinase, …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Physiological and Psychological Effects of Ekadashi Upavasa (Fasting Ritual) on Women: A Prospective cohort study on Metabolism, Immunity, and Mental Clarity
Abstract: Background: Ekadashi Upavasa, a traditional bi-monthly fasting ritual, is believed to offer physical, mental, and spiritual benefits. However, its scientific impact on metabolism, immunity, and mental clarity remains underexplored. This prospective cohort study evaluates these effects among women practicing the ritual at Krishna Temple, Amloh, over six months. Methods: A total of 800 women aged 25–50 years were recruited from Krishna Temple, Amloh, for this study, conducted from June 2024 …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 67–70 Read article
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A Study on Automatic Feedback Control by Image Processing for Mixing Solutions in a Microfluidic Device
Abstract: Precise and rapid mixing of chemical and biological reagents is a critical yet challenging aspect of microfluidic systems, often limited by laminar flow conditions and the need for manual or pre- programmed interventions. Existing mixing strategies frequently lack real-time adaptability and closed-loop control, hindering reproducibility and the execution of complex reaction protocols. This work presents an innovative automatic feedback control system utilizing the study on real- time image processing to …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
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Lemon Sign: The Diagnostic Indicator for Spina Bifida
Abstract: The “lemon sign” is a distinctive ultrasonographic finding that serves as a diagnostic indicator for spina bifida, a congenital neural tube defect characterized by incomplete closure of the spinal cord. This sign is observed in fetal imaging and is considered an early and reliable marker for detecting spina bifida, particularly when combined with other prenatal diagnostic tools such as the “banana sign.” The lemon sign is characterized by a flattened, …
Published in International Journal of Midwifery Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 1–6 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 · pp. 60–78 Read article
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Modified Listless Set Partitioning in Hierarchical Trees (MLS) for Memory Constrained Image Coding Applications
Abstract: SPIHT image coding algorithm is a very effective state-of-art technique for compression of wavelet transformed images. However, the use of three continuously growing linked lists, limit its applications to achieve high quality images in memory constrained environments.The No List SPIHT (NLS) is an attempt to implement SPIHT algorithm without lists, but it uses 4 bits per coefficient state markers to keep track of significant/insignificant information of pixels/sets. This paper presents …
Published in Current Trends in Signal Processing · Vol. 2, Issue 1-3, 2012 · pp. 56–66 Read article
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Recombinant Lactobacillus helveticus PJ4-Down Regulates TLR4 Mediated Inflammatory Responses in Sucrose Induced Diabetic Rats: A Novel Therapeutic Approach
Abstract: High sucrose diet (HSD) is known to induce type 2 diabetes. Recombinant Lactobacillus helveticus PJ4 was constructed to express the InuJ gene under the xylose promoter resulting in the secretion of inulosucrase enzyme in gastrointestinal tract which polymerizes the fructose moiety of sucrose to inulin type fructans. L. helveticus (pSLP-InuJ-Vhb) transformant (LHI) was intragastrically administered to rats fed with HSD diet. The composition of fecal microbiota and short-chain fatty acids …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 44–65 Read article
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Immunology as Applied to Farm Animal Welfare: General Principles and Interventions
Abstract: Animal welfare is a state of animal’s well-being as indicated by scientific evidence and preferably quantifiable read-out of its health, nourishment, behavior and living conditions. Farm animals are reared for food and other purposes in different production systems. Farm animal welfare, particularly in intensive production systems, is an emerging concern of society at large, consumers of farm animal-source food in particular. Changing climate and weather patterns, intensive crop-farming and high-density …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 1, 2018 · pp. 1–13 Read article