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47 articles for “antibiotics”
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Innovations in Tuberculosis Management: Advancements in Drug-Resistant TB Treatment and Rapid Diagnostics
Abstract: Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, exacerbated by the increasing prevalence of drug-resistant strains, such as multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB). Despite advancements in first-line and second-line treatments, resistance to conventional antibiotics has complicated therapeutic strategies, necessitating novel approaches. This mini review explores emerging advancements in TB treatment, including gene editing technologies, such as CRISPR, which offer potential for precise targeting of drug-resistant bacterial …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Ecological, Economic, and Medical Roles of Fungi: Insights from Mycology in Addressing Global Challenges"
Abstract: The large and diverse kingdom of fungi is vital to ecosystems, industry, agriculture, and medicine. Due to its ecological and biotechnological value, mycology has grown in importance. Fungi are crucial to natural systems and human life, decomposing organic materials, developing mutualistic interactions with plants, and producing antibiotics and fermented products. Recent advancements in molecular biology and genomics have significantly enhanced our understanding of fungal diversity, physiology, and evolutionary processes. These …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
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Trichoderma: beneficial fungus for sustainable agriculture
Abstract: As environmentally beneficial substitutes for chemical pesticides, Trichoderma species are being utilized in agriculture more and more. Disease suppression, increased plant growth, and increased tolerance to environmental stress are just a few advantages they provide. These fungi are used in a wide range of cropping systems and formulations around the world. Their use is growing worldwide, particularly in Asia and Europe. In contemporary crop management, items derived from Trichoderma are …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 25–29 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Typhoid Fever: Etiology, Clinical Manifestations, Diagnosis, and Management
Abstract: Typhoid fever is a systemic and potentially life-threatening infectious disease caused by Salmonella enterica serotype Typhi, which primarily spreads through the fecal-oral route via ingestion of contaminated food and water. It continues to be a major global public health concern, particularly in developing and low-resource countries where poor sanitation, inadequate personal hygiene, and unsafe water supplies prevail. The disease is characterized by prolonged high-grade fever, abdominal discomfort, headache, loss of …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 1–4 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article