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109 articles for “acetic acid”
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Synthesis of Novel Sugar-Benzimidazole Derivatives
Abstract: Conversion of some unprotected and unmodified aldoses with o-phenylene diamine to aldo-imidazoles using iodine catalyst in acetic acid solution has been applied, according to a known method. Accordingly some novel derivatives have been synthesized. Characterization of the synthesized products has been performed by M.P., chromatography, IR and mass spectra. Keywords: Sugar-benzimidazole derivatives, IMs, carbohydrate labelingCite this Article Al-Difar Hussniya A, Basma Younis, Basma Saad Baaiu et al. Synthesis of Novel …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 2, 2017 · pp. 1–4 Read article
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Effect of Sintering Temperature on Dielectric Behavior of Y0.95Ca0.05MnO3 Manganites
Abstract: Ca-doped mixed valent Y0.95Ca0.05MnO3 (YCMO) manganites, synthesized using cost effective acetic acid based modified sol-gel method, sintered at various temperatures, exhibit a strong effect of sintering temperature on the structure, microstructure, dielectric and activation energy (Ea). Oxygen vacancies, located at the grain boundaries of the nanostructured YCMO samples, play an important role in governing the dielectric behavior. The peak behavior, observed in imaginary part of dielectric (εʹʹ vs. T) plots, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 3, Issue 2, 2013 · pp. 24–29 Read article
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Protein-Tyrosine Phosphatase-1B (PTP-1B) Inhibitory Perspectives of Hydroxylated Chalcones: Exploration through Docking Studies
Abstract: The current research emphasized on exploring the Protein-Tyrosine Phosphatase-1 B (PTP-1B) inhibitory potentials of hydroxylated chalcone derivatives against PDB ID: 4I8N (PTP-1B in complex with an inhibitor [(4-{(2s)-2-(1,3-benzoxazol-2-yl)-2-[(4-fluorophenyl)sulfamoyl]ethyl}phenyl)amino](oxo)acetic acid) by molecular docking approach using the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The current molecular docking analysis of some hydroxylated chalcone derivatives have presented a profound inhibition of the antidiabetic target PTP-1B by interacting with the amino acid residues …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 1, 2019 · pp. 4–8 Read article
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Evaluation of Anthelmintic, Analgesic and Neuropharmacological activity of Heliotropium indicum
Abstract: The present study was performed to evaluate the anthelmintic, analgesic and neuropharmacological activity of the methanol extract from the leaves of Heliotropium indicum. Anthelmintic activity was investigated using earthworm (Pheretima posthuma) & fresh leaf juice of the plant. In anthelmintic activity test, the time of paralysis for fresh juice was range from 7 min 55 s to 26 min 55 s whereas the time ranges for standard drug albendazole was …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 1, 2019 · pp. 31–38 Read article
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Effect of Algal Toxin-Anatoxin on the Growth of Acorus calamus L.
Abstract: AbstractThe growth of Acorus calamus L. in Bheemasandra accession of Tumkur district, Karnataka state was studied. The roots of Acorus calamus L., are used to build immunity in the children. Narayan Das Prajapathi 2003 in his book “A handbook of medicinal plants” reports that, it has a stimulating, nervine and anti-spasmodic properties and acts as a rejuvenative for the brain and nervous system. It is used to promote cerebral circulation. …
Published in Research & Reviews : Journal of Botany · Vol. 4, Issue 1, 2015 · pp. 26–32 Read article
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Variation in Activity of Lipase Immobilized on Chitosan and Alginate Nanoparticles by Changing Concentration of the Preparatory Reagents
Abstract: Chitosan and alginate nanoparticles were prepared by ionic gelation method. The concentrations of each of the preparatory reagents (for chitosan: acetic acid, chitosan, sodium sulphate, glutaraldehyde and for alginate: calcium chloride, alginate, glutaraldehyde) were altered to check their consequences. Lipase was chemically crosslinked to these nanoparticles. Enzymatic assay was carried out for every alteration separately. To visualize the changes in each reagent at every step a precise table is incorporated …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 3, 2017 · pp. 14–22 Read article
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Evaluation of Anthelmintic, Analgesic and Neuropharmacological Activity of Merremia hederacea
Abstract: The aim of the present study was to evaluate the phytochemical screening, anthelmintic activity, analgesic properties and neuropharmacological activity of the leaf extract of Merremia hederacea (Family: Convovulaceae). After preliminary phytochemical screening, the leaf extract of Merremia hederacea contain flavonoids, tannins, alkaloids and reducing sugars. Anthelmintic activity test was done by comparing the time of paralysis and the time of death of earthworms Pheretima posthuma compared with the standard drug, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 1, 2020 · pp. 28–33 Read article
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HPTLC Method Development and Validation of Genistein and Daidzein Estimation in Mucuna cochinchinensis Seed Extracts
Abstract: Aim: The current study was designed with the objective to estimate the concentration of Genistein and Daidzein in ethyl acetate extract of Mucuna cochinchinensis by high-performance thin-layer chromatography (HPTLC).Methods: The separation of bioactive compounds was performed using mobile phase, Toluene: n-Butanol: Glacial Acetic Acid: Water (1:4:2:2) and detected at wavelength 254 nm. The method was validated for linearity, accuracy, precision, limit of detection (LOD) and limit of quantification (LOQ) by …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 16–25 Read article
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Characterization of Endofungus Aspergillus nomius EF8-RSM Isolated from Aloe vera Western Ghats of Karnataka India
Abstract: The objective of the present research investigation was to reveal the versatile nature of endophytic Aspergillus nomius EF8-RSM. The fungus was purified from Aloe vera, Western Ghats of Karnataka, India and sequence was submitted at NCBI under the accession number MN871698. The fungus successfully produced Indole acetic acid at the rate of 49.21±6.1 μg/ml and phosphate solubilization was confirmed with solubilization index (1.63). The fungus showed production of siderophore, ammonia …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 22–30 Read article
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Anticancer and Antioxidant Property of Bunium bulbocastanum Fruits Various Fractions
Abstract: Bunium bulbocastanum (family Apiaceae) fruits are normally used as a culinary spice for years. Since antioxidant property has a significant role in preventing oxidative stress, which has been demonstrated to be a major cause in the pathogenesis of cancer, the present study was aimed to evaluate the in vitro antioxidant and cytotoxic effect of Bunium bulbocastanum fruit extracts. Standard in vitro antioxidant assays such as reducing power, super oxide scavenging, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 1, 2016 · pp. 9–13 Read article
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Preparation of Methyl Esters of Solid Acids from Litsea Consimilis
Abstract: This study focuses on the extraction and characterization of fatty acids from the seed oil of Litsea consimilis and their subsequent conversion into methyl esters. The oil demonstrated high iodine and Reichert-Meissl values, indicating a significant content of unsaturated and short-chain fatty acids. Glyceride analysis revealed that trilaurin constitutes over 90% of the triglycerides, confirmed through melting point analysis and hydrolysis yielding lauric acid as the sole component. The oil …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 129–134 Read article
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Deciphering the Pathophysiology of Migraine: Understanding Trigeminovascular System Activity and the Importance of the Gut-Brain Axis
Abstract: Migraine, a prevalent and disabling neurological condition, manifests in distinct phases: premonitory, aura, headache, postdrome, and interictal. Being a primary contributor to adult disability, it presents a substantial economic challenge on a global scale. Even with extensive research spanning centuries, the complete grasp of its root causes continues to evade us. This intricate neurovascular disorder primarily involves local vasodilation of intracranial and extracerebral blood vessels, coupled with simultaneous stimulation of …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 50–61 Read article
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Significance of TE Domain and Genetic Variations in FASN Gene in Dairy Animals
Abstract: The interest in the bovine fatty acid synthase (FASN) gene has increased during the last few years. FASN is a multifunctional enzyme that catalyzes de novo biosynthesis of long-chain saturated fatty acid, and alteration of this enzyme may affect economic traits including fatty acid composition. FASN is involved in fat metabolism and is an important candidate gene affecting fat composition of milk because of its central role in de-novo lipogenesis …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 33–38 Read article
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HPLC and Tandem MS Device for the Recognition of Emtricitabine and Tenofovir Alafenamide in K2EDTA Human Plasma Utilizing Emtricitabine 15ND2 Tenofovir D5 as an IS
Abstract: Developed very impressionable, discriminating, and exact extreme-efficiency liquid chromatographytandem bulk spectrometry form for measurement of Emtricitabine and Tenofovir Alafenamide in human plasma. Emtricitabine15ND2 Tenofovir D5 was used as a within the standard (IS). The samples were divided on Phenomenex Kinetex C18 5 μm 100A, 100*4.6 mm procession utilizing Acetonitrile: 0.2% formic acid, 60:40 V/V as movable state, the retention period of Emtricitabine: 1.36 minutes (±0.5 minutes), Emtricitabine 15ND2: 1.36 minutes …
Published in Research and Reviews: A Journal of Toxicology · pp. 30–38 Read article
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HPLC and Tandem MS Device for the Recognition of Emtricitabine and Tenofovir Alafenamide in K2EDTA Human Plasma Utilizing Emtricitabine 15ND2 Tenofovir D5 as an IS
Abstract: Developed very impressionable, discriminating, and exact extreme-efficiency liquid chromatography-tandem bulk spectrometry form for measurement of Emtricitabine and Tenofovir Alafenamide in human plasma. Emtricitabine15ND2 Tenofovir D5 was used as a within the standard (IS). The samples were divided on Phenomenex Kinetex C18 5 µm 100A, 100*4.6 mm procession utilizing Acetonitrile: 0.2% formic acid, 60:40 V/V as movable state, the retention period of Emtricitabine: 1.36 minutes (±0.5 minutes), Emtricitabine 15ND2: 1.36 minutes …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 2, 2022 · pp. 30–38 Read article
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Determining the Antagonistic Potential of Lactobacilli Isolated from Commercial Curd Samples against the E. coli
Abstract: Curd has always been an important source exhibiting a plethora of Lactobacilli. Lactobacilli are rod-shaped bacteria, capable of producing short-chain fatty acids, lactate, and acetate by carbohydrate fermentation process. A study was done to determine the antimicrobial activity of isolated and identified Lactobacilli bacteria from commercial curd samples against standard strains of E. coli. All the 10 samples were found have lactobacilli strains. The antagonistic activity of these strains was …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 9, Issue 2, 2020 · pp. 27–30 Read article
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Analysis of Diethanolamide Reaction by using FTIR Technique
Abstract: The purpose of this work is to study the amidification reaction for production of diethanolamide from ethyl acetate and diethanolamine by using sulfuric acid catalyst. The amidation, which is the reaction between ethyl acetate and diethanolamine, was held in a glass batch reactor with mole ratio 1:1 using acid catalyst (H2SO4) 0.5% (w/w) and 200 rpm stirring. The reaction temperature is 160°C constant, and sampling was performed after every 30 …
Published in Journal of Catalyst & Catalysis · Vol. 3, Issue 1, 2016 · pp. 7–10 Read article
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Risk Assessment of Batch Sulfonation Process using Fault Tree and Bowtie
Abstract: The current study looks into the batch reactor's sulfonation reaction's safety features. Acetanilide, thionyl chloride, and chlorosulphonic acid are used in the sulfonation reaction under consideration to generate acetyl sulphonyl chloride as well as by-products such HCl and SOx. Steam starts the process, which is exothermic in nature. Water is then chilled to maintain a temperature of 50°C and a pressure of one atmosphere. The Hazard and Operability (HAZOP) analysis …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 3, 2024 · pp. 50–56 Read article
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Development and Validation of RP-HPLC Method for Determination of Thermal Degradation Impurity in Macrolide Immunosuppressant Substance and Drug Product
Abstract: The present study describes a simple and stability-indicating reverse phase high-performance liquid chromatography (RP-HPLC) method for the quantification of the thermal degradation impurities of Tacrolimus (FK506) namely Ally ester rearrangement impurity (Impurity R) in Tacrolimus capsules and drug substances. Successful separation of impurity R from Tacrolimus, its other related substances and its tautomers were achieved on a Zorbax XDB C8 (150×4.6 mm, 5 μm) and detector of UV at 210 …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 1, 2016 · pp. 14–19 Read article
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Extraction of Natural Dye from Red Rose Flowers
Abstract: In this research work, locally available red flowers of the red rose are selected for the extraction of anthocyanin. Ethanol solvent was used to extract anthocyanin from flowers. Different methods are used to obtain natural dyes from flowers. FTIR, pH, and UV tests were performed to characterize the extracted anthocyanin. The pH differential method was used to measure the total anthocyanin content in red rose flowers. The color of the …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article