Search
193 articles for “Drug information”
-
A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
-
Accelerate Drug Development with Pharmacokinetic Softwares
Abstract: During continuously evolving technologies and mechanized equipments, there has been a tremendous growth in the pharmaceutical sector over the past few decades. New technologies, software, devices, and techniques are being developed or researched upon with each passing day. By leveraging pharmacokinetic software, researchers can efficiently analyze vast datasets from preclinical and clinical studies, extracting actionable insights that inform decision-making early in the development cycle. This predictive capability not only accelerates …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
-
Differential Scanning Calorimetry, Thermogravimetric Analysis, and Dynamic Mechanical Analysis for Advanced Medical Materials
Abstract: Modern healthcare depends on advanced medical products that come up with new ways to care for and help patients. Characterizing these products is important to make sure they are safe, effective, and work well. While there are many analysis methods, Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), and Dynamic Mechanical Analysis (DMA) are the most important ones for checking the temperature and mechanical qualities of medical materials. By measuring the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 57–72 Read article
-
Pharmacognostic and Phytochemical Investigation of Pods of Albizia lebbeck (L.) Benth.
Abstract: Albizialebbeck (L.) Benth. is well known as the medicinal plant in the Ayuerveda, Siddha and Unani system of medicines. The drug isolated from different parts of this plant is used in different sciences of medicines like Unani, Ayuerveda, allopathic, Sidda, naturopathic and homeopathic. The present investigation deals with pharmacognostical and primary phytochemical screening of the pod of Albbizzialebbeck (L.) Benth. The pharmacognostical studies include fluorescence, organoleptic evaluation and physicochemical analysis. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 1, 2019 · pp. 10–15 Read article
-
A Review on T POXX (TECOVIRIMAT)—A New Bioweapon Against Small Pox
Abstract: As an author in the present review, I have provided all the available information regarding T POXX (TECOVIRIMAT)—a new bioweapon against small pox—like its synonym, history of discovery and approval, chemical structure, pharmacology, adverse drug reactions, drug interactions, safety concerns, contraindications, warnings/cautions, preclinical and clinical trial information and all other information after thoroughly searching in all the available resources. I hope this can be helpful to all the healthcare professionals …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 2, 2018 · pp. 9–11 Read article
-
Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
-
ASSESSMENT ON THE KNOWLEDGE, ATTITUDE AND PRACTICE OF SUBSTANCE USE AMONG PREPARATORY STUDENTS OF MEKELLE.
Abstract: Background: Substance abuse has been defined by Asuni et al. as 'excessive or inappropriate use of psycho-active substance by a person; such use being considered or judged to be illegal/immoral by the culture and resulting in harm to the person or society'. Globally, the UNODC estimates that between 155 and 250 million people, or 3.5% to 5.7% of the population aged 15–64 years, had used illicit substances at least once …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 3, 2018 · pp. 6–26 Read article
-
A Study and Report on Impact of Pharmacovigilance and Drug Safety Monitoring Practices in Promotion of Rational Drug Usage in General Medicine Departments of Hospital
Abstract: The present study reports on impact of pharmacovigilance and drug safety monitoring practices in promotion of rational drug usage in General Medicine Department of ESI hospital with an objective of identification and reporting of Drug Related Problems. It is a prospective observational study & conducted for a period of six months from November 2020 to April 2021. A sample size of 120 patients were randomly opted for this study, out …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 2, 2023 · pp. 24–40 Read article
-
Exploring Pharmacological Mechanism Of Pteridines And Its Derivatives Against Neurodegenerative Disorders Using Network Pharmacology And Molecular Docking Techniques
Abstract: Objectives: Pteridines have been identified via various research and shown therapeutic efficacy in Neurodegenerative disorders(ND) preclinical models. In the current study, a network pharmacology technique was applied to determine the underlying mechanism of the pteridines' protective effects on ND. Network pharmacology was utilised in order to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 03, 2022 · pp. 1–13 Read article
-
Machine Learning Techniques Based on Sentiment Analysis for Drug Recommendation System
Abstract: A recommended system can help the user make sense of complex information and make well-considered choices. User-generated material is conveyed in human language in various nuanced ways, making it difficult to provide recommendations based on a study of attitudes. However, there has been a shortage of research devoted to health and medical concerns compared to more mainstream areas like product and media critiques and dining-out recommendations. Sentiment analysis (SA) of …
Published in Journal of Computer Technology & Applications · Vol. 14, Issue 3, 2023 · pp. 83–94 Read article
-
Toxicological Examination of Dopamine's Involvement in Substance Abuse: An Overview
Abstract: Dopamine, classified as a catecholamine, is an essential organic compound that plays a crucial role in the brain's reward system and regulatory processes. It is instrumental in reinforcing pleasurable activities through repeated engagement. Acting as a neurotransmitter, dopamine is released in various brain regions, including the striatum and accumbens, and is absorbed by neurons through receptors.This review aims to comprehensively outline the mechanisms of dopamine release and its pivotal role …
Published in Research and Reviews: A Journal of Toxicology · Vol. 13, Issue 3, 2023 · pp. 22–25 Read article
-
In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
-
Cloud Enabled Machine Learning Framework for Medicine System
Abstract: The Medicine Generic App is a cutting-edge mobile application designed to empower users with information about generic medications. Given the rising expenses of healthcare and prescription medications, this app acts as a useful resource for consumers to make informed decisions regarding their medication options. The Medicine Generic App aims to promote generic drug usage, reduce healthcare costs, and improve medication management for users. By providing detailed information and price transparency, …
Published in International Journal of Mobile Computing Technology · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
-
Elemental Impurities: A Review
Abstract: The ICH Q3D is an important guideline to harmonize control of elemental impurities. The guideline sets strict limits for final drug products, limits for excipients, active pharmaceutical ingredients and other pharmaceutical drug products. The analysis of elemental impurities in the pharmaceutical products is most important in pharmaceutical industries. In the last decade noteworthy progress has been made in the analysis of elemental impurities. The changes from using special reagents which …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 17–21 Read article
-
FDA Drug Approvals 2024: A Comprehensive Review
Abstract: The year 2024 has been pivotal for the pharmaceutical industry, with the U.S. Food and Drug Administration (FDA) granting approval to a diverse array of new drugs. These approvals highlight significant strides in therapeutic innovation, targeting a spectrum of diseases from rare genetic disorders to prevalent chronic conditions. This article provides a detailed examination of the FDA-approved drugs of 2024, focusing on their therapeutic indications, mechanisms of action, and the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 28–46 Read article
-
Study to Assess the Knowledge of Staff Nurses about Practicing Narcotic Policies in Selected Hospitals ICU in View to Prepare Information Pamphlet
Abstract: Narcotic use and diversion among nurses is a growing problem. Substance abuse is the major reason listed by the State Board of Nursing for disciplinary action. Staff nurses needs to be aware regarding narcotic and diversion. In the present study, 20 staff nurses were selected by purposive sampling from selected hospital from Miraj, Maharashtra, India in the year 2015. Knowledge questionnaire was used for data collection. Results demonstrated that majority …
Published in Research and Reviews: A Journal of Health Professions · Vol. 6, Issue 1, 2016 · pp. 4–8 Read article
-
Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
-
Medicinal Potential of Cullen corylifolium in Ageing and Ageing Related Diseases
Abstract: Cullen corylifolium is a tropical medicinal plant of the Fabaceae family, generally known as Babchi/Bakuchi in various regions of Asia. Cullen corylifolium is a traditional phyto-therapeutic plant of China used to manifest various pathological conditions since ages, possesing round and dark brown seeds with a rough texture. Cullen corylifolium has been previously reported to possess various properties such as antioxidant, anti-inflammatory and can be used as a solution to treat …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 21–32 Read article
-
A Study of the Effect of Educative Drug Awareness Session on the Knowledge of Young Adolescents, their Teachers and Parents
Abstract: Background: Changes in lifestyle, along with easy access to media and internet have among other factors lowered the age of exposure to drugs and alcohol among youth. Within this context, the parent teacher association of a private high school in Mumbai approached Kripa Foundation to conduct a preventative educative drug awareness session for their students (Grade 8 to 12), their teachers and parents. The session aimed to (i) increase the …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 2, 2017 · pp. 10–22 Read article
-
A STUDY ON IMPACT AND OUTCOMES OF PHARMACOVIGILANCE AND ITS IMPLICATIONS, PRACTICES OVER ADR IDENTIFICATION, REPORTING AND MONITORING IN PROMOTION OF RATIONAL DRUG USAGE.
Abstract: The present study reports on impact of pharmacovigilance and drug safety monitoring practices in promotion of rational drug usage in General Medicine Department of ESI hospital with an objective of identification and reporting of adverse drug reactions. It is a prospective, observational study & was conducted for a period period of 8 months from Jan 2022 to Aug 2022. A sample size of 126 patients were randomly opted for this …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 3, 2022 · pp. 8–27 Read article