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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Experimental Investigation of Mechanical Properties of the Composite Materials Reinforced by Agro-based Waste Materials
Abstract: In this work, experiments were carried out to develop the glass fiber reinforced composites using the hand layup method and analyze the mechanical properties of the GFRP hybrid composites. The ultimate Tensile strength (UTS) using rice as a filler (GFRPC/R) was 3.04% and 12.89% higher than coir and wheat as filler, respectively. The hybrid composite using coir as a filler (GFRPC/C) revealed 12.54% greater flexural strength, and the hybrid composite …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 186–196 Read article
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Comparative Study to Assess the Attitude of Higher Secondary School Students Regarding Career Counselling in Selected Rural and Urban Schools of Kashmir
Abstract: Background: Career counselling is a process that involves working with a professional to explore and understand various aspects of one's personality, skills, interests, values, and goals to make informed decisions about your career. Aim: The main aim of the study was to assess the attitude of higher secondary school students regarding career counselling in selected rural and urban schools of Kashmir. Methods: This study employed a descriptive research design using …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 11–18 Read article
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Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats
Abstract: The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. "The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 10–16 Read article
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TOPSIS-Driven Optimization of FFF Process Parameters for Mechanical Strength Enhancement
Abstract: In this study, the application of the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) method for optimizing Fused Filament Fabrication (FFF) process parameters to enhance the tensile and flexural strength of Polylactic Acid (PLA) material-based 3D printed components is explored. This investigation delves into the intricate relationship between key parameters, such as layer height, print speed, infill density, print temperature, and nozzle diameter, and their impact …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 246–255 Read article
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Hemoglobin is the Breath of Life within Our Cells: An Update
Abstract: Hemoglobin is a fascinating protein found in human red blood cells. This specialist protein carries oxygen from your lungs to every cell in your body, functioning as a little delivery system. While hemoglobin’s stronghold on oxygen is necessary, releasing it at the right time is a delicate challenge. This adaptable protein masterfully balances holding on to its oxygen cargo or releasing it swiftly. This article explores how hemoglobin achieves this …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 25–31 Read article
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Influence of the Load, Sliding Speed, and Weight Fractions on Wear of a Hybrid Aluminium Metal Matrix Composite
Abstract: The vital focus of the research is intended in examining the aspect that impact the rate of wear for a hybrid aluminium metal matrix composite. The percentages of two reinforcements that are employed, the weight, and the sliding speed are the variables taken. The procedure entails employing the vortex-stir casting process to produce the hybrid composite. Utilizing a pin-on-disc apparatus, the fabricated composite materials are evaluated in compliance with the …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 188–198 Read article
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Sustainable Approaches for Examining the potential use of nanoparticles in future research
Abstract: Theoretical stagnation can always be an eminent danger for any research field. Therefore, the contemporary research themes are constantly explored and examined through battery of examination. Based on the aforesaid rationale, this study examined the counterfeit purchase intention of the youth based on different constructs such as Market mavenism, Cool consumption, Postmodernism, Schadenfreude, Public self-consciousness, Generational norms, and Generational Identification. The questionnaire was administered for collecting the data the responses …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 1–8 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Experimental Study on Replacement of Cement and Fine Aggregate with Marble Dust and Copper Slag
Abstract: With the ever-growing challenge of managing escalating waste materials globally, this paper explores sustainable solutions in construction through the utilization of marble dust and copper slag. The rapid generation of waste poses severe environmental and health threats, necessitating innovative strategies for responsible waste management. Local availability and the potential to enhance concrete strength make marble dust and copper slag attractive candidates for the partial replacement of cement and fine aggregate. …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 169–176 Read article
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Evaluating the Impact of a Structured Teaching Program on Caregivers’ Awareness of the Adverse Effects of Bottle Feeding in a Chosen Community Area: A Quasi-Experimental Study in Shri Goindwal Sahib, Tarn-Taran, Punjab
Abstract: Background of the study: Breast milk is the recommended nourishment for all infants. All the babies regardless the type of delivery should be given early and exclusive breastfeeding up to 6 months of age. Except breastfeeding, there are many practices followed by caregivers like bottle feeding, cup feeding, paladai feeding, katori and spoon feeding etc. but one of the most common practice is India is bottle feeding which causes various …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 39–44 Read article
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Assessing Efficacy and Safety: Oxytocin Monotherapy vs. Oxytocin + Carbetocin Combination Therapy
Abstract: Objective: Comparing the Effectiveness between Oxytocin monotherapy and Oxytocin + Carbetocin. Methods: A prospective, non-randomized, observational study focusing on 221 women with CS was conducted. The patients eligible based on inclusion and exclusion criteria were screened and final sample size was 139. Individual patient data including patient demographics, medical history, OT notes, pre and post CBC reports, and safety data were obtained from the patient records. The study compared between …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 40–51 Read article
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An Open Labelled Parallel Arm Randomized Clinical Trial of Tuvaraka Oil Prepared By Two Different Method In The Management of Pama
Abstract: In Ayurveda, all skin diseases have classified mainly into two groups i.e., Mahakushtha (major skin diseases) and Kshudrakushtha (minor skin diseases). Tuvaraka [Hydnocarpus laurifolia (Dessnt).Sleumer] is one among the most useful drugs for the treatment of Kushtha (Various skin diseases) and Madhumeha (Diabetes Melitus). Pama is described under Kshudra Kushtha. which can be correlates with scabies. Aim: To evaluate the clinical efficacy of Tuvaraka oil prepared by modified method and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 29–36 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Exploring Glucagon-like peptide-1 as a Target Protein for Diabetes Mellitus Treatment: Molecular Docking and Pharmacokinetic Analysis of Phytocompounds from Momordica charantia
Abstract: Objective: This study aimed to use molecular docking techniques to explore the potential of GLP-1 (glucagon-like peptide-1) as a target protein for the treatment of diabetes mellitus, a chronic metabolic disease marked by elevated blood glucose levels. Given its crucial role in maintaining insulin secretion and glucose homeostasis, GLP-1 may serve as a future target for diabetes therapy. Method: The study employed a multi-phase method. Initially, protein extraction was carried …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 8–20 Read article
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Evaluating the Impact of a Structured Teaching Programme on Knowledge About Endometriosis Among First-Year Degree Students in a Chosen College in Wayanad District
Abstract: Introduction: The primary objective of this study is to evaluate the impact of a structured teaching program on the understanding of endometriosis among female students enrolled in the first year of a chosen degree arts and science college in Wayanad district. The specific goals include evaluating the baseline knowledge about endometriosis among first-year degree students in the selected college and determining the effectiveness of the structured teaching program in enhancing …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 20–24 Read article
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A Study to Assess the Effectiveness of Body Mechanics Training Programme on Reducing Low Back Pain Among Nursing Officers Working in Selected Hospitals, Bangalore
Abstract: Background: Low Back Pain (LBP) is a common work related injury and costly problem among the nursing profession. Numerous studies indicate a greater occurrence of back pain and work-related back injuries among nursing officers in comparison to other occupations. Prevention of LBP is a very important technique to maintain proper body mechanics. This study aimed to assess the effectiveness of body mechanics training programme on reducing low back pain among …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 29–62 Read article
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CFD Analysis of Electric Vehicles Battery Pack: A Research Study
Abstract: The goal of the project is to keep the battery temperature within the specified range and to improve the battery pack's performance under different temperature settings. To achieve these goals, we employ software to analyze the data and provide the necessary output. With model-based design, you can understand the dynamic behavior. For this project, a CAD model was produced with Creo Parametric. We used the STAR CCM+ Software for analysis …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 2, 2023 · pp. 28–32 Read article
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Advancements in Smart Home Technology: Evoview’s Impact and Reflection
Abstract: The “EvoView” project is a sophisticated blend of design and technology, featuring RaspberryPi 4, a sleek display panel, a meticulously crafted wooden frame, and a one-way glass mirror. This innovative mirror transforms into an information hub, displaying real-time weather updates, current time, news, and upcoming events seamlessly. A strategic decision was made when the Raspberry Pi 3 Plus 4 was selected as the project's central processing unit. This option allows …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 1, 2024 · pp. 16–21 Read article
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A Comparative Techno-economic Analysis of Hydrogen Production Processes from Locally Available Resources in Nigeria
Abstract: In this work we report result of techno-economic analyses of three hydrogen production pathways - Steam Methane Reforming (SMR), SMR with Carbon Capture (SMR+CC) and Proton Exchange Membrane electrolysis (PEM) – using integrated process-cost simulation-estimation methodologies. Process modeling and simulation is performed with Aspen Hysys® and Aspen Plus® (V10). Cost modeling and estimation is based on full lifecycle cost of production using the Levelized Cost of Hydrogen (LCOH) approach. Feedstock …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 1, 2024 · pp. 29–46 Read article