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843 articles for “Structure-Based”
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Targeting Homogentisate Dioxygenase Dysfunction in Alkaptonuria: Investigating Curcuma longa’s Therapeutic Potential
Abstract: Objectives: Alkaptonuria is known to have a faulty gene HGO in the metabolic process. In the present research work, the focus is towards investigating the therapeutic capabilities of the Curcuma longa upon the faulty Homogentisate dioxygenase gene using ligand-protein binding, which would assist in the corrective tyrosine metabolism. Methods: This study is based on the computational approach using different phytochemicals for evaluation of the potency against the abnormal Homogentisate dioxygenase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 1–11 Read article
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Advances in Polymer Chemistry for Biomedical Applications: Innovations in Composite Materials
Abstract: Polymer chemistry has seen remarkable progress in recent years, particularly in the biomedical field, where novel polymeric materials are transforming the development of medical devices. These advancements have led to the creation of biocompatible, durable, and multifunctional polymer-based solutions that enhance patient care, surgical precision, and treatment outcomes. The application of polymer chemistry in biomedical sciences has revolutionized medical device manufacturing. Polymers offer unique advantages such as flexibility, biocompatibility, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 287–292 Read article
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Next-Generation Conductive Polymer Composites for Flexible and Wearable Electronics
Abstract: The rising demand for flexible and wearable electronics has accelerated research into conductive polymer composites (CPCs) due to their lightweight nature, electrical conductivity, and mechanical flexibility. Despite significant advancements, challenges such as reduced conductivity under mechanical deformation and limited durability persist. This study aims to develop next-generation CPCs with enhanced conductivity, flexibility, and self-healing capabilities. Hybrid nanofillers—graphene, carbon nanotubes (CNTs), and silver nanowires (AgNWs)—were incorporated into bio-based conductive polymers through …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 550–566 Read article
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Numerical Investigation of AA5053 Through Equal Channel Angular Pressing Technique: An Overview
Abstract: Equal channel angular pressing is recognized as the predominant method for bulk severe plastic deformation processing and has been employed for refining the grain structure in numerous metals and alloys. This study utilized finite element analysis to examine the processing of metallic billets through simple shear deformation. For the study, the die channel angle was chosen based on achieving the minimum energy consumption to induce maximum uniform strain. Among the …
Published in Trends in Machine design · Vol. 12, Issue 3, 2025 · pp. 40–47 Read article
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A Concise Overview of Recent Developments and Uses in Nano-Silica and Nanoparticles Encased in Silica
Abstract: Nano-silica and silica-coated nanoparticles have gained significant attention lately due to their exceptional chemical and physical properties, including a high surface area-to-volume ratio, adjustable porosity, thermal and chemical stability, biocompatibility, and ease of surface modification. These characteristics make them versatile materials applicable in various scientific and industrial sectors. Their ability to control particle size, shape, and surface traits allows them to be effectively utilized in catalysis, drug delivery, biosensing, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 696–704 Read article
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Sustainability Driven Marketing in the Polymer Composites Sector: Green Positioning and Circular Economy Strategies
Abstract: Marketing strategies have progressively shifted toward sustainability, fundamentally transforming the polymer composites sector. Green positioning focuses on showcasing a product’s environmental advantages, whereas circular economy strategies emphasize reuse, recycling, and waste reduction. These approaches have gained considerable interest amid rising consumer demand for eco-conscious products and stricter environmental regulations. Sustainable polymer composites contribute to lower carbon emissions and improved resource management. Such materials are particularly valuable in sectors where ecological …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 319–330 Read article
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Innovative Approaches in Bioinspired and Biomimetic Membrane Technologies: Bridging Nature and Engineering
Abstract: Bioinspired and biomimetic membranes represent a ground breaking advancement in membrane technology, offering innovative solutions to critical global challenges in water purification, chemical separation, and energy conversion. These membranes leverage the exceptional transport properties of biological systems, particularly through the incorporation of aquaporin proteins, which facilitate rapid and selective water transport. This review synthesises recent developments in aquaporin-based membranes, highlighting their remarkable efficiency in desalination processes, where they serve as …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 53–60 Read article
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A Threshold-Weighted Mathematical Fusion Model for Epidemic Outbreak Prediction Using SEIR Residual Dynamics and Cloud-Based Machine Learning
Abstract: Accurate prediction of epidemic outbreaks is critical for effective public health management, resource planning, early warning generation, and timely intervention by municipal authorities. Traditional compartmental models such as Susceptible–Exposed–Infectious–Recovered (SEIR) offer valuable epidemiological insights and mathematical interpretability; however, they may not adequately capture the complex nonlinear relationships present in real-world urban health systems. Conversely, data-driven machine learning techniques can identify hidden patterns in large datasets but often lack epidemiological structure …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 2, 2026 · pp. 12–19 Read article
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Experimental and CFD Investigation of an Epoxy-Based Thermally Conductive Polymer Composite U-Tube Shell-and-Tube Heat Exchanger: A Lightweight Alternative to Conventional Metal Systems
Abstract: Shell-and-tube heat exchangers continue to play a critical role in industrial thermal systems; however, their conventional design based on fully metallic materials often leads to challenges related to weight, corrosion, and cost. In recent years, thermally conductive polymer composites have emerged as promising alternatives, offering improved corrosion resistance and design flexibility. In this study, the thermo-hydraulic performance of a U-tube shell-and-tube heat exchanger is investigated by partially replacing conventional metallic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 685–700 Read article
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Conceptual Design and Static Model Analysis of Landing Gear
Abstract: An aircraft's landing gear system plays a critical role in effectively managing and dissipating kinetic energy generated during the landing impact, as well as mitigating vibrations induced by the aircraft's passage over irregular runway surfaces. This capability is indispensable for the proper functioning of a well-designed landing system. Among the various types of shock absorber landing gear systems employed in aircraft, the oleo-pneumatic shock absorber stands out as the most …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 145–163 Read article
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Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
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Fabrication, Mechanical Characterization and Biodegradation Analysis of Polylactic Acid Based Composite for Medical Sutures
Abstract: Wound closure is surgical aids relies heavily on sutures, which help maintain proper tissue alignment and supporting healing. The effectiveness depends on factor such as the type of wound, required mechanical strength, risk of infection and characteristics like absorbability and thickness of the martial. The efficacy of sutures is determined by their material properties and structural characteristic’s, which affect their mechanical properties. The primary objective of this study was to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Webpage Extraction and Retrieval Chatbot
Abstract: Web scraping is a fundamental technique for automating data extraction in big data applications. While multiple implementations exist, few leverage Python’s Beautiful Soup library for efficient and structured data retrieval. This project aims to develop a web scraper and retrieval system that extracts relevant information from web pages, stores it in a vector database (Milvus), and enables intelligent querying using semantic search and generative AI. The system is designed to …
Published in International Journal of Satellite Remote Sensing · Vol. 3, Issue 2, 2025 · pp. 1–7 Read article
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A Comprehensive Review on Lead-Zinc Tailings as An Alternate Material in Concrete
Abstract: Lead-Zinc Tailings are high volume wastages that are dumped in the open area of mine after extraction of minerals from ore. Tailings have high content of heavy metals that creates lot of environmental problems like air, water, land and also marine drainage along with it creates risk to human life, so tailings required better and safe management to overcome these problems. Now, this review begins with the utilization of Lead …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 227–230 Read article
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Evaluating an ai-supported experiential learning intervention: a quasi-experimental study of the joyful saturday model for student engagement and holistic development
Abstract: Student disengagement, declining academic motivation, and passive classroom participation remain major challenges in modern higher education systems. Traditional lecture-based teaching methods often fail to accommodate diverse learning styles and do not sufficiently promote active participation or collaborative learning. To address these challenges, the present study evaluates the effectiveness of Joyful Saturday, a structured experiential learning initiative designed to improve student engagement, motivation, and holistic development through interactive academic activities supported …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 79–88 Read article
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Comparative Seismic Response of Irregular High-Rise RCC 25 Storey Buildings with and without Shear Walls Considering P–Delta Effect
Abstract: The seismic performance of high-rise reinforced concrete (RCC) buildings is significantly affected by plan irregularity, lateral stiffness distribution, and second-order (P–Delta) effects. Irregular structural configurations may generate torsional response and increased deformation demand under seismic excitation while geometric nonlinearity further amplifies displacement and internal forces in tall structures . This study presents a comparative seismic assessment of a G+24 storey RCC building having overall plan dimensions of 30,000 mm × …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 2, 2026 Read article
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Framework-Based Optimization of Catalysis Efficiency through Reaction Pathway Engineering
Abstract: The rational design of heterogeneous catalysts through framework-based approaches has emerged as a transformative strategy for controlling reaction pathways and enhancing catalytic efficiency. This paper examines recent advances in the optimization of catalytic performance through engineered frameworks, including metal-organic frameworks (MOFs), zeolites, and related porous materials. By integrating computational methods with experimental validation, researchers have achieved unprecedented control overactive site architecture, reactant confinement, and elementary reaction steps. This work reviews …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 88–99 Read article
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Eu3+/Gd3+ doubly doped ions in SrCO3-Al2O3-B2O3-SiO2 glasses for optical and White light applications
Abstract: The present work deals with the optical analysis of SrCO3-Al2O3-B2O3-SiO2 glass materials doubly doped with Eu3+/Gd3+ ion were prepared by melt quenching technique. These are studied by XRD, physical properties, FITIR, optical absorption and luminescence spectroscopy. The XRD measurements are conducted to verify the amorphous form of prepared material and structural modifications can be explained by the FTIR spectra. The thermal stability of the glass matrix is measured by the …
Published in Journal of Semiconductor Devices and Circuits · Vol. 11, Issue 2, 2024 Read article
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Thin Film Solar Cells: Progress in Materials, Fabrication, and Efficiency Enhancements
Abstract: Thin film solar cells (TFSCs) have drawn a lot of interest because of their potential for efficient and reasonably priced photovoltaic energy conversion. Their flexibility, low weight, and lower material consumption make them a desirable substitute for conventional solar cells made of crystalline silicon. This review explores recent advancements in TFSC technology, with a focus on materials, fabrication techniques, and efficiency improvements.Various thin-film materials, such as amorphous silicon (a-Si), perovskite, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 37–42 Read article
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Comparative Evaluation of Dodders, Giloy, Onion Peels and Fruit Waste-Prepared Composite Biochar Polymeric Adsorbent (CBPA) For Use in Wastewater Treatment
Abstract: Due to pollutants that have a negative impact on water bodies, wastewater treatment has attracted a lot of attention throughout the years. In many developing countries domestic and industrial wastewater treatment plants are lacking or not working efficiently for detergents due to the refractory nature of such chemicals. Generally the industrial wastewater is directly discharged into the existing water bodies (drains, nallahs etc.) after primary settling tanks. These refractory contaminants …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 72–80 Read article