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1945 articles for “WAS gene” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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A Narrative Review on Osteogenesis Imperfecta and Its Management
Abstract: Osteogenesis imperfecta (OI), sometimes referred to as brittle bone disease, is a heterogeneous illness characterized by short stature, several fractures, and distorted bones. The main contributing factor to OI is mutations in the genes needed to produce type 1 collagen. While severe OI is perinatally fatal, mild OI can occasionally not be detected until maturity. The frequency of Osteogenesis imperfecta ranges from about 1:15,000 to 1:20,000 births. Five kinds of …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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ChatGPT Based Voice Assistant for Blind People
Abstract: The proposed system for converting speech input into text format to facilitate interaction with ChatGPT is a sophisticated integration of hardware and cloud-based services. Utilizing state-of-the-art technologies, it facilitates seamless communication between users and the AI model. At the outset, the microphone serves as the input device, capturing audio signals from the user's speech. These signals are then amplified to ensure clarity and fidelity before being transmitted to the ESP32 …
Published in Journal of Operating Systems Development & Trends · Vol. 11, Issue 2, 2024 · pp. 23–31 Read article
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AI Chatbot for Expressing Visual Content
Abstract: Recently, the artificial intelligence (AI) chatbot for expressing visual content has shown remarkable multi-modal capabilities. It can recognize funny features in photos and create webpages straight from handwritten text. These characteristics are uncommon in earlier vision language models. We think the use of a more sophisticated large language model (LLM) is the main factor behind vision verbalizer's superior multi-modal generating capabilities. We introduce vision verbalizer, which employs a single projection …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 2, 2024 · pp. 11–19 Read article
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article
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Automated Math Solver Assist with LLM RAG
Abstract: The challenges of solving complex mathematical problems often hinder efficiency in various scientific and engineering domains. This project proposes an innovative solution to these challenges by integrating automated math solvers with large language model (LLM) retrieval-augmented generation (RAG). The proposed system aims to streamline mathematical problem-solving processes, offering a robust and precise tool for real-time recognition, classification, and solution generation. This work provides a novel method of automating the solution …
Published in Current Trends in Signal Processing · Vol. 14, Issue 2, 2024 · pp. 25–30 Read article
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Preserving Saccharomyces cerevisiae Culture for Bee Health and Production
Abstract: Saccharomyces cerevisiae, a single-celled fungus also known as baker’s and brewer’s yeast, is extensively used in brewing, baking, and winemaking due to its robust genetics and utility as a model organism in scientific research. Its role extends beyond these applications into apiculture, where it is utilized to produce supplements and pollen replacements for honeybees. These yeast-based supplements are crucial, especially during times of pollen scarcity or colony stress, as they …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 23–27 Read article
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Glitches in the Implementation of Bioinformatics in Medical Settings: A Comprehensive Review
Abstract: Bioinformatics is a dynamic field at the intersection of biology, computer science, and information technology, offering new possibilities in medicine by enabling a deeper understanding of genomics, molecular biology, and personalized treatment approaches. Its integration into healthcare could greatly enhance diagnostics, enable tailored treatments for individuals, and facilitate the analysis of large biological datasets. However, despite its potential, several barriers impede its successful implementation in clinical settings. These include technical …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Cancer Tumor Markers And Its Latest Trends
Abstract: Almost one in six deaths occurs due to abnormal cell division; these cells are termed cancer cells in general. Cancer cells collaborate to multiply and metastasize. Our aim is to awaken awareness in people to understand their bodies and motivate them for early diagnosis,as cancer is the second leading cause of death after cardiovascular disease. The human body is a marvellous creation in nature; in response to cancer, it creates …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 25–38 Read article
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Municipal Material Management
Abstract: The increase in global prosperity and population has led to a significant rise in the generation of Municipal Solid Waste (MSW), posing serious threats to public health and the environment. This study explores the global state of MSW generation, composition, and management strategies, comparing the effectiveness of various technologies across 59 developed and developing countries. A total of 19 criteria for the selection of MSW management technologies are discussed, highlighting …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 11–15 Read article
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Innovative Approaches to Reducing Data Traffic in IoT Networks Using Deep Learning and Compressive Sensing
Abstract: The exponential growth of internet of things (IoT) devices has posed unprecedented challenges in managing the massive data generated by real-time monitoring, automation, and analytics. Existing network infrastructures lack scalability, bandwidth, and suffer from latency problems, further making data transmission less efficient. This study surveys innovative approaches using deep learning and compressive sensing to reduce IoT data traffic. Deep learning is able to upgrade data processing by means of very …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 2, 2024 · pp. 46–62 Read article
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Reimagining Plastic Waste: The Impact of Eco-Bricking on Student Engagement and Community Sustainability
Abstract: Plastic pollution poses a severe threat to the environment, impacting ecosystems, wildlife, and human health. With millions of tons of plastic waste generated globally each year, innovative solutions for waste management are essential. This paper explores the eco-bricking initiative at Sovanagar High School, which transforms plastic waste into eco-bricks—sustainable building materials used for constructing green walls, benches, and other structures on the school campus. By effectively reducing plastic waste, this …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 23–25 Read article
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The Perpetuation of Psychological Wounds: A Comprehensive Review of Intergenerational Trauma in Indian Patriarchal Society
Abstract: The transmission of trauma effects from one generation to the next is known as intergenerational trauma, and it is particularly common in patriarchal civilisations such as India. Laws, economy, and social conventions are shaped by patriarchy, a societal framework that primarily gives males power, authority, and advantages. This perpetuates gender inequity and marginalises women. Aim: The purpose of this review is to examine how trauma is transmitted throughout generations in …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 20–26 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Studies on Some Pyrgomorphinae (Pyrgomorphidae: Pyrgomorphoidea) of Bihar
Abstract: The subfamily Pyrgomorphinae belongs to the family – Pyrgomorphidae. Members of this subfamily have brightly colored bodies owing to which they are generally known as “gaudy grasshoppers”. It had been an expansive check for grasshoppers corresponding to diversified and rich foliage as well as different ecological conditions, downfall, moisture and temperature. Surveys were conducted in colorful seasons of important agrarian areas in different regions of Patna quarter for data collection …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 26–33 Read article
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Comparative Evaluation of Dodders, Giloy, Onion Peels and Fruit Waste-Prepared Composite Biochar Polymeric Adsorbent (CBPA) For Use in Wastewater Treatment
Abstract: Due to pollutants that have a negative impact on water bodies, wastewater treatment has attracted a lot of attention throughout the years. In many developing countries domestic and industrial wastewater treatment plants are lacking or not working efficiently for detergents due to the refractory nature of such chemicals. Generally the industrial wastewater is directly discharged into the existing water bodies (drains, nallahs etc.) after primary settling tanks. These refractory contaminants …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 72–80 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article