Search
149 articles for “structural shape”
-
Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
-
Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
-
Drug Marketing in Tropical Regions and Its Effect on Pharmacovigilance Awareness and Reporting
Abstract: Drug marketing practices in tropical regions present a complex interplay between pharmaceutical promotion, healthcare infrastructure limitations, and public health outcomes. These regions – characterized by high disease burden, socio-economic disparities, and diverse healthcare delivery systems – often experience unique challenges in ensuring safe and rational drug use. Aggressive and sometimes unregulated marketing strategies by pharmaceutical companies may significantly influence prescribing behavior, patient compliance, and, ultimately, pharmacovigilance systems. Pharmacovigilance, defined as …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 · pp. 1–17 Read article
-
Innovative Applications of Smart Materials in Aviation: A Comprehensive Review
Abstract: Smart materials are transforming the aviation industry by offering innovative solutions that enhance performance, safety, and sustainability. The use of smart materials can enhance the efficiency, safety, and longevity of aerospace structures by sensing, responding, and adjusting to environmental changes in real time. The objective of this review is to examine how smart materials can be used in aviation, especially in the field of sensor networks, control systems, and structural …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 114–132 Read article
-
An Optimize Formulation to Synthesis of size Controlled Hydrophobic Starch Acetate Nanoparticles using Box- Behnken Design
Abstract: The best way to improve the overall performance of native starch is by chemical modification. In recent years, hydrophobically modified starch has attracted considerable attention for the design and manufacture of novel nanoparticulate drug delivery carriers. The purpose of this research was to synthesize hydrophobic starch nanoparticles (NPs) and to optimize process factors through the use of response surface methodology (RSM). The corn starch acetate (CSA) NPs was synthesized using …
Published in Journal of Polymer & Composites Read article
-
Configuration and Properties of Group III Elements in the Periodic Table
Abstract: Group III elements comprise those found in the third column of the periodic table, including boron, aluminum, gallium, indium, and thallium. These elements possess three valence electrons in their outermost shell, characterized by the electron configuration ns2np1, which influences their location and characteristics within the periodic table. The distribution of electron pairs, formal charges, oxidation states, and molecular morphologies of Group III elements and their compounds are illustrated in this …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 2, 2025 · pp. 23–30 Read article
-
Image-Based Quantitative Mapping of Structure Property Relationships in Polymer Composite Materials
Abstract: The performance of polymer composite materials is intrinsically governed by their microstructural architecture, which is shaped by manufacturing conditions and constituent interactions. Despite extensive experimental characterization efforts, establishing transparent and quantitative structure–property relationships from microstructural images remains a challenge. In this study, an explainable image-driven framework is developed to systematically correlate microstructural features with composite property indicators. Microstructure images are processed to identify voids, fibers, and filler phases, from which …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 188–196 Read article
-
Evaluation of Critical MMAW Welding Defects Using Computer Simulation in Industrial Manufacturing Systems
Abstract: Manufacturing is one of the key sectors of any countries GDP and welding is one of the prime manufacturing processes of the manufacturing sector. Welding has several notable advantages over mechanical joining techniques, including higher structural integrity, design flexibility, and cost and weight lowers. Welded products/structures are subjected to serious issues of residual stresses and distortions. The performance and sturdiness of the welded structures are severely impacted by weld remaining …
Published in International Journal of Industrial and Product Design Engineering · Vol. 3, Issue 2, 2025 · pp. 18–26 Read article
-
Computational Study of Sombor Index on Generalized Abid–Waheed Graphs for Polymer Modeling
Abstract: This study investigates the topological properties of generalized Abid Waheed graphs. Development of theoretical models in chemistry, reducing computational complexity while analysing large molecules or networks Abid Waheed graphs play a significant role. Motivated by these findings, the research was extended to encompass generalized Abid Waheed graphs, characterized by r cycles of order s. A notable similarity between Abid Waheed graphs and Jahangir graphs was observed. The potential applications of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 267–274 Read article
-
Bridging the Gap: Exploring the Social and Economic Dimensions of Gender Equality
Abstract: Gender equality is a fundamental human right and a critical prerequisite for sustainable social and economic development. Despite notable progress in recent decades, significant disparities persist worldwide, particularly in the social and economic domains. This paper explores the multifaceted nature of gender inequality, examining how structural, cultural, and institutional barriers continue to shape unequal access to resources, opportunities, and decision-making power. By analysing key sectors such as education, healthcare, labour …
Published in Recent Trends in Social Studies · Vol. 3, Issue 1, 2026 · pp. 19–24 Read article
-
Effect of Adverse Childhood Experiences on Adult Attachment Styles and Help Seeking Behaviour Among Youth
Abstract: Psychological development is deeply influenced by early environments, where personal experiences, cultural norms, and structural factors intersect. Beyond individual adversity, societal conditions shape cognitive, emotional, and social functioning, ultimately influencing attachment patterns and help-seeking behaviour in adulthood. The current study explores the influence of adverse childhood experiences on adult attachment styles and help-seeking behaviour among youth. 140 participants (70= males, 70= females) aged 18-25 years were involved in the study. …
Published in International Journal of Children · Vol. 2, Issue 2, 2025 · pp. 25–34 Read article
-
Study of Behavior of Buckling Restrained Bearing Frame Along with Soil Structure Interaction
Abstract: Lateral forces due to earthquake are the major consideration for design of earthquake resisting structures, these forces can be resisted by various systems like braced frames, shear walls, moment frames, etc. Energy dissipation is one of the most convenient option for earthquake resistance, as it can absorb input energy from earthquake protecting the main structure. Past research revealed that the Buckling Restrained Braces (BRB) are the best type of energy …
Published in Journal of Construction Engineering, Technology & Management Read article
-
Comparative Seismic Response of Irregular High-Rise RCC 25 Storey Buildings with and without Shear Walls Considering P–Delta Effect
Abstract: The seismic performance of high-rise reinforced concrete (RCC) buildings is significantly affected by plan irregularity, lateral stiffness distribution, and second-order (P–Delta) effects. Irregular structural configurations may generate torsional response and increased deformation demand under seismic excitation while geometric nonlinearity further amplifies displacement and internal forces in tall structures . This study presents a comparative seismic assessment of a G+24 storey RCC building having overall plan dimensions of 30,000 mm × …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 2, 2026 Read article
-
An Experimental Investigation of Impact of Polyproplene as a Partial Replacement in Concrete
Abstract: India, as a developing nation, will require high-strength and high-performance concrete for future infrastructure projects. Fibrous concrete, which incorporates fibers to enhance structural integrity, is one such material that could meet these demands. With different concrete fibrous materials, shapes, distributions, orientations, and densities, fibrous concrete takes on different characteristics. Polypropylene is a lightweight synthetic fiber that enhances the structural strength of concrete and helps prevent the formation of cracks. In …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 3, 2024 · pp. 1–6 Read article
-
Commercialization of Smart Polymers in Advanced Composite Structures for Industrial Applications
Abstract: The commercialization of smart polymers in advanced composite structures represents a significant rise in material science, particularly for industrial applications. These smart polymers show unique properties such as self-healing, shape memory, & responsiveness to environmental disturbances, making them ideal for a wide range of applications. In this paper, the researcher explores the advancements in developing and applying smart polymers within composite structures, focusing on their potential. Revolutionize industries like atmosphere, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 70–81 Read article
-
Asymmetrical Light Propagation in 2D Photonic Crystal Structure
Abstract: In this work, using Plane Wave Expansion (PWE) and two-dimensional Finite Difference Time Domain (2D-FDTD) methods, we design a structure that shows the high asymmetry in propagation of light. Structure is based on two-dimensional Photonic Crystal (2D-PC) consisting of square lattice (39 X 39) of infinitely long circular rods of refractive index 2.9 in the background of refractive index 1. Radius of rods is 0.15a, where a is the lattice …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 69–74 Read article
-
Emerging Trends in Civil Engineering: Sustainability and Digital Transformation
Abstract: Civil engineering has long played a pivotal role in shaping society’s infrastructure, focusing traditionally on construction, design, and the structural integrity of buildings, roads, and bridges. However, recent years have witnessed a profound transformation in the field, driven by the urgent need for sustainable practices and the rapid evolution of technology. This paper provides an in-depth analysis of the latest trends that are redefining civil engineering, with a particular emphasis …
Published in Recent Trends in Civil Engineering & Technology · Vol. 14, Issue 3, 2024 · pp. 8–11 Read article
-
Current Developments In 4D Printing Technology
Abstract: The perception of four-dimensional (4D) printing expertise was prompted through the time dimension inclusion in three-dimensional (3D) printing. Many other industries, including engineering, health, and the arts, have revealed a great deal of attention it. Recently, innovations in bioscience have been established that can be implemented using 4D printing. The ability to integrate time with situational variations has many benefits, but perceptibility and adaptability are merely two. Smart material, stimulus, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 108–120 Read article
-
4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release
Abstract: Four-dimensional printing technology has transformed the pharmaceutical landscape, offering unprecedented opportunities for innovation in drug development and delivery. This emerging technology enables the creation of complex geometries and customized structures, facilitating the design of personalized medications tailored to individual patient needs. Personalized dosing and drug release profiles, customized pill shapes and sizes for improved swallowability. Enhanced drug solubility and bioavailability, rapid prototyping and testing of pharmaceutical products. Development of complex …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 08–16 Read article
-
Innovations in Polymer Chemistry for Smart Composite Materials in Building Applications
Abstract: Driven by the need to reduce maintenance costs and environmental impacts, researchers have developed smart polymers that not only sense damage but also autonomously respond to external stimuli such as temperature, mechanical stress, and light. In the built environment, these advanced polymers—particularly shape memory polymers (SMPs)—offer unique self-healing, self-sensing, and adaptive properties that enhance the durability, safety, and energy efficiency of structures. The emergence of smart polymers marks a significant …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 699–707 Read article