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221 articles for “adverse effects”
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A Comprehensive Review: Emerging Nanotechnology in Cancer Drug Delivery
Abstract: Nanotechnology has become a groundbreaking strategy in cancer therapy, especially in drug delivery systems, offering improved treatment effectiveness while minimizing the adverse effects associated with traditional methods. This review presents an in-depth analysis of recent progress in nanotechnology for cancer drug delivery, emphasizing the design, mechanisms, and practical applications of nanoparticle-based systems. Nanoparticles, such as liposomes, dendrimers, and gold nanoparticles, offer unique advantages, including improved drug solubility, targeted delivery to …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 24–33 Read article
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Studying the effects of Exposure to Chemicals on The brain and Nervous System and The risk of Chemical Pollution
Abstract: Scientific research and studies on chemical pollution show that exposure of the brain and nervous system to chemicals causes serious damage ranging from cognitive, motor, and nerve cell disorders to chronic diseases such as Alzheimer's and neurological paralysis. These substances (such as lead ions, mercury, solvents that combine and dissolve easily in the blood, and pesticides) disrupt neurotransmitters and cause cell damage, especially during the early stages of body development. …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 Read article
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A Global Impact of Pharmaceutical Pollution
Abstract: Pharmaceutical products play an important role in our daily life in which consumption medicine is essential in need of curing the disease. As the requirement of the pharmaceuticals is more important in human life the production of medicine is in more demanded in global level in our day-to-day life. The most important aspects are the other side in which the pollution of the pharmaceuticals is caused due to the manufacturing, …
Published in Research and Reviews: A Journal of Toxicology Read article
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Therapeutic Potential of Terminalia arjuna Bark in the Management of Hemorrhoids: A Comprehensive Review
Abstract: Background: Hemorrhoids appear frequently among anorectal disorders since they create vascular swelling together with pain symptoms, while leading to bleeding and mucosal tissue tending to slide out. Though effective therapy exists, traditional treatments produce various adverse effects and lead to recurrence and inconsistent patient following of medical recommendations over the long term. Plantbased therapeutic medicines have gained rising demand, which leads experts to investigate medicinal plants with established pharmacological effects. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
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Rosemary: A Natural Way to Improve Brain Health and Cognitive Function
Abstract: Cognitive decline is a common consequence of aging, often leading to diminished quality of life. Although conventional drug treatments, such as anticholinesterase inhibitors, are available for managing cognitive decline, they are not always effective in older adults and may even induce adverse effects. As a result, there has been growing interest in natural alternatives, particularly traditional herbal medicines, for their potential cognitive-enhancing properties. Among these, Rosmarinus officinalis (Rosemary) has gained …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 30–36 Read article
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The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article
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Assessment of Soil Heavy Metal Contamination Using Proximal Spectroscopy and Hyperspectral Remote Sensing: A Brief Review and Potential Application in Vietnam
Abstract: Soil contamination by heavy metals is a pressing global environmental concern, impacting ecosystem health, agricultural productivity, and human well-being. In Vietnam, rapid economic growth and industrialisation exacerbate these concerns, with diverse landscapes and intensive land use practices increasing susceptibility to heavy metal pollution. This study provides an overview of the assessment of soil heavy metal contamination, focusing on proximal spectroscopy and hyperspectral remote sensing techniques and their potential application in …
Published in Journal of Remote Sensing & GIS · Vol. 16, Issue 2, 2025 · pp. 48–57 Read article
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AI-Powered Drug Delivery: Revolutionizing Formulation Science
Abstract: Artificial Intelligence (AI) is emerging as a groundbreaking tool in revolutionizing Drug Delivery Systems (DDS), offering promising advancements in precision, efficiency, and personalized treatment strategies. The integration of AI technologies into pharmaceutical research and development is transforming how drugs are formulated, delivered, and monitored in real time. By leveraging machine learning algorithms and data analytics, researchers can design drug delivery models that are not only more effective but also tailored …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 48–61 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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Flexural Vibration of Non-Uniform Beam on Bi-Parametric Foundation Under Harmonic Moving Load with Non-Classical Boundary Conditions
Abstract: The dynamic response to harmonically varying moving loads of non-uniform elastic beam resting on bi-parametric foundation with non-classical boundary condition, time dependent in particular is examined in this paper. Here, the beam is considered non-uniform, with the moment of inertia and the distributed mass varying continuously along the span L as functions of the position 𝑥. In order to guarantee a more stable structure and a reduce risk of resonance, …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 2, 2025 · pp. 28–42 Read article
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Thermal Effects in High-Power Laser Systems: Modeling and Mitigation
Abstract: High-power laser systems are increasingly employed in industrial manufacturing, defense, medical procedures, and scientific research due to their ability to deliver high energy density with excellent spatial coherence. However, the performance and reliability of these systems are significantly influenced by thermal effects arising from optical absorption, non-radiative recombination, and inefficient heat dissipation within laser gain media and optical components. These thermal phenomena lead to adverse effects such as thermal lensing, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 9–13 Read article
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Integrating Atmospheric Science: Understanding Greenhouse Gases, Aerosols, and Air Quality Dynamics
Abstract: Atmospheric science investigates the Earth’s atmospheric systems to understand their composition, dynamics, and the implications for climate, weather, and air quality. This review explores five primary areas within the field: atmospheric composition, atmospheric modeling, remote sensing, air pollution, and boundary layer dynamics, highlighting critical challenges and advancements. Rising levels of greenhouse gases (GHGs), including carbon dioxide and methane, continue to drive global warming, while feedback mechanisms—like cloud interactions and surface …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 32–35 Read article
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Automatic Brake Failure Indication with Auxiliary Braking System
Abstract: Accidents in vehicles often happen due to diverse factors, with brake failure being a significant contributor resulting from inadequate maintenance and product defects. To protect human lives and reduce the risk of accidents, effective monitoring of brake systems is vital in the automotive industry. Vehicle safety encompasses not only the prevention of accidents but also the mitigation of their adverse effects on human health. Today’s cars come with innovative safety …
Published in Journal of Automobile Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 1–7 Read article
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Systematic Analysis of the Pharmacological Properties of Different Plant Parts of Madhuca sp.
Abstract: Madhuca sp., a perennial tree belonging to the Sapotaceae family, are widely distributed across South and Southeast Asia. It holds considerable value across the food, beverage, and pharmaceutical sectors. The growing interest among cultivators, agronomists, and industry stakeholders stems from the diverse bioactive potential documented across different parts of the plant, including the bark, leaves, seeds, and flowers. Traditional and emerging evidence points to a wide spectrum of pharmacological actions, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 Read article
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Electroconvulsive Therapy in the Management of Schizophrenia: A Systematic Review in Emergency Nursing Practice
Abstract: Electroconvulsive therapy (ECT) is a well-established treatment for various psychiatric disorders, including schizophrenia, particularly in cases where patients are resistant to conventional treatments. Schizophrenia, a chronic and severe psychiatric disorder, often presents with a combination of positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and emotional blunting), and cognitive impairments. While antipsychotic medications are the primary treatment, approximately 20–30% of individuals with schizophrenia do not …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 43–48 Read article
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Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape
Abstract: Cannabinoids, the bioactive compounds derived from the Cannabis sativa plant, have garnered increasing interest for their potential role as nutritional supplements. This abstract provides a succinct overview of cannabinoids as nutritional supplements. This review delves into the multifaceted aspects of cannabinoids, particularly their interaction with the endocannabinoid system (ECS) and their potential health benefits. The exploration begins by elucidating the intricate relationship between cannabinoids and the ECS, a vital regulatory …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 48–53 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Protective Effects Of Curcumin Against Osteoporosis And Its Molecular Mechanism
Abstract: One of the most prevalent metabolic disorders is osteoporosis (OP), which primarily affects postmenopausal women and the elderly. It is often associated with gradual loss of bone density, ongoing destruction of bone microstructure, and increased risk of osteoporosis. Pharmacotherapy is the primary approach for treating and preventing osteoporosis. However, persistent medication therapy invariably results in drug responses and particular adverse effects. Therefore, scientists continue to search for new monomeric compounds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 16–23 Read article