Search
32 articles for “Pharmaceutical Manufacturing Processes”
-
Optimizing Manufacturing Processes with Taguchi Method in Production Engineering
Abstract: The Taguchi Method, pioneered by Genichi Taguchi, stands as a powerful optimization tool within the realm of production engineering. This paper delves into the principles, applications, and significance of the Taguchi Method in enhancing manufacturing processes. With a focus on minimizing variation and improving performance, this methodology plays a crucial role in addressing challenges faced by industries in their pursuit of operational excellence. The core components of the Taguchi Method, …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
-
Accelerate Drug Development with Pharmacokinetic Softwares
Abstract: During continuously evolving technologies and mechanized equipments, there has been a tremendous growth in the pharmaceutical sector over the past few decades. New technologies, software, devices, and techniques are being developed or researched upon with each passing day. By leveraging pharmacokinetic software, researchers can efficiently analyze vast datasets from preclinical and clinical studies, extracting actionable insights that inform decision-making early in the development cycle. This predictive capability not only accelerates …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
-
Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
-
Regulatory Requirements for Pharmaceutical Product Registration in Zambia
Abstract: There is a significant burden of diseases in Zambia and its neighboring countries, such as malaria, HIV/AIDS, and other ailments. These health challenges necessitate a high consumption of pharmaceutical products. Currently, the majority of essential health drugs in Zambia are imported from outside of Africa. This reliance on external sources presents an opportunity for new investments in the local manufacturing of pharmaceutical products. Although Zambia may not be the largest …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 33–41 Read article
-
Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
Liposomes Innovative Role as a Drug Delivery System: A Detailed Analysis
Abstract: The first nanomedicine to be approved for use in clinical settings was liposomes. These are the spherical vesicles with a bilayer of phospholipids enclosing a middle empty aqueous region. Because of their extraordinary potential to stop medication deterioration and lessen unwanted effects, liposomes are being utilized more and more for targeted drug distribution. For targeted drug delivery, the pharmaceuticals can be integrated into the liposomes' aqueous space or phospholipid bilayer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 25–32 Read article
-
Microneedles: A Modern Breakthrough in Drug Delivery Systems
Abstract: Microneedles (MNs) represent a revolutionary and transformative advancement in the realm of transdermal drug delivery systems, which are designed to facilitate the administration of therapeutic agents through the skin. These exceptionally small, micron-scale needles penetrate the stratum corneum, thereby enabling the direct delivery of pharmacological agents into the underlying dermis or the upper epidermis, consequently enhancing bioavailability while simultaneously circumventing the detrimental effects of first-pass metabolism and the degradation that …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
-
Synthesis, Identification and Bio Evaluation of New Thiophene Derivatives
Abstract: Thiophene is considered one of the most effective cyclic sulfur compounds in organic and pharmaceutical chemistry due to its high stability in various chemical reactions. It plays a key role as an antifungal agent in treating skin allergies, as well as in the preparation of polymers, rubber, and other materials. Recent research has focused on incorporating sulfur compounds into the synthesis of organic compounds because of their high stability in …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 31–43 Read article
-
Formation, Characterization and Microscopic Study of Four- and Five-membered Ring
Abstract: Types of organic compounds are famous for many industrial and medical applications, including azo compounds, one of the largest groups involved in the manufacture of various organic compounds. For example, they are considered as initiators of free radicals in the polymerization reactions of alkenes used in the manufacture of plastics. Most of cyclic compounds have nano properties which make this type of compound important in organic field. It is also …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 1–15 Read article
-
Investigations on Anthocyanin and Its Regulatory Role
Abstract: Anthocyanin is the most widely studied and abundant group of natural pigments. It has been gaining increased attention for its potential health benefits. This vibrant, water-soluble pigment is found in fruits, vegetables, and flowers, and is responsible for the colors of many of the foods we eat. Anthocyanins are not only responsible for the aesthetic appeal of these foods, but they are also believed to have powerful antioxidant, anti-inflammatory, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 32–37 Read article
-
An Optimize Formulation to Synthesis of size Controlled Hydrophobic Starch Acetate Nanoparticles using Box- Behnken Design
Abstract: The best way to improve the overall performance of native starch is by chemical modification. In recent years, hydrophobically modified starch has attracted considerable attention for the design and manufacture of novel nanoparticulate drug delivery carriers. The purpose of this research was to synthesize hydrophobic starch nanoparticles (NPs) and to optimize process factors through the use of response surface methodology (RSM). The corn starch acetate (CSA) NPs was synthesized using …
Published in Journal of Polymer & Composites Read article
-
Nano-enhanced Bio-based Phase Change Materials: A Brief Review
Abstract: The high latent temperatures and variable melting points of bio-based phase change materials make them ideal for thermal control. This covers heat regulation for medical and pharmaceutical items, building comfort, and high-end electronics and automobiles. In recent years, research and application of energy-saving materials and technologies in buildings has increased strength. Modern construction technology aims to keep old and new structures energy efficient. TES employing PCMs is an energy-efficient approach. …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 15–27 Read article