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42 articles for “Iso-flavonoids”
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Phytochemical and Pharmacological Study of Seed Extract of Vigna radiata from Bhopal District (M.P.)
Abstract: Vigna radiata, the seed of moong bean (a common pulse), is majorly rich in nutrients with biological activities. It has been used in traditional medicine for the treatment of a number of diseases. The aim of the present study was to perform preliminary pharmacological and phytochemical research of moong bean seeds. Various physicochemical parameters including extractive values and ash values of moong bean seeds were found. The powdered seeds were …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 3, 2020 · pp. 4–10 Read article
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Antimicrobial Activity of Alcoholic and Aqueous Extracts of Tinospora cordifolia
Abstract: 1024x768 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The success of chemotherapy lies in the continuous search for new drugs to counter the challenge posed by resistant strains. Ethanolic and aqueous extracts of plant Tinospora …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 1, 2011 · pp. 1–6 Read article
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Gossypetin Inhibits ROS Generation in HeLa and HepG2 Cell Lines
Abstract: Antioxidants are known for their ability to neutralize the reactive oxygen species present within the living system. These antioxidants are mainly secondary metabolites present in plant products and are generally known as nutraceuticals or bioactive compounds. Antioxidant can be categorized into many categories based upon their structure and activities like flavonoids, anthrocyanins and carotenoids. Flavonoids are heterogeneous polyphenolic compounds having beneficiary effect on human body and are also known to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 25–31 Read article
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Allelopathic Nature of Cucumis Prophetarum Linn.
Abstract: ABSTRACTCucumis prophetarum Linn. is perennial, monoecious climber, commonly growing weed, belonging to family Cucurbitaceae. The whole plant of C. prophetarum is medicinally important. Plant pacifies vitiated dysentery, diarrheic diseases, flatulene, skin diseases, antivenin and general debility. Dispending medicinally uses, our study has found that this weed is allelopathic in nature. To check the allelopathic activity, C. prophetarum was assessed for the effects of their extracts on the growth of mature …
Published in Research & Reviews : Journal of Botany · Vol. 1, Issue 1, 2012 · pp. 16–21 Read article
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Anti-Microbial Potential of Onion Peel Extracts
Abstract: Onion (Allium cepa L.) is a source of bioactive compounds, particularly flavonoids such as quercetin, and possesses antioxidant and beneficial properties to health. Onion skin, which is normally considered as waste, has more of these compounds compared to the edible portion. This research sought to isolate and analyze the antioxidant and antimicrobial activity of onion skin with ethanol and hexane using Soxhlet and column chromatography techniques. Antioxidant activity was maximum …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 1–10 Read article
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Chemical Profiling and Antibacterial Activity of Punica Granatum L against Pathogens Causing Bovine Mastitis
Abstract: The antibacterial activity of aqueous and methanol extracts of Punica granatum L was investigated against bovine mastitis causing bacterial pathogens- Streptococcus agalactiae, Staphylococcus aureus, Streptococcus uberis, Escherichia coli, Streptococcus dysagalactiae and coagulase negative Staphylococcus aureus by agar disc diffusion method [3] isolated locally from clinical cases. The results obtained in the present study scientifically proved and suggest the use of Punica granatum for treating mastitis causing organism. The phytochemical screening …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 1, 2014 · pp. 12–15 Read article
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A Review of Herbal Photoprotective Agents: From Traditional Knowledge to Modern Sunscreen Formulations
Abstract: Continuous exposure of skin to UV rays leads to tanning, premature aging, sunburn, pigmentation, and skin cancer. Sunscreens are widely used to protect the skin from these harmful stimuli. However, sunscreen components may interfere with other health concerns like irritation, itching, allergic reactions, and distinct environmental damage. This major concern initiated the introduction of herbal photoprotective agents, which are eco-friendly, safer for use, and rich in antioxidants (preventing free radicals). …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 8–13 Read article
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Antifungal, Antioxidant Activity and Phytochemical Analysis of Extracts from Vitex rivularis (Lamiaceae)
Abstract: The present study was designed to investigate the biological properties of methanolic extracts of leaves and seeds from Vitexrivularis. Leaves and seeds extracts were prepared by maceration in methanol. Phytochemicals analysis was performed by colorimetric method, chemical reaction method and high-performance liquid chromatography (HPLC). The broth microdilution method was used to evaluate the in vitro activity against three strains of Candida albicans and 17 isolates of two yeast species (Candida …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 1, 2020 · pp. 23–48 Read article
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Phyto-chemical Screening, In Vitro Anti-arthritic Study, Formulation and Evaluation of Ethanolic Extract of Helicteres Isora Fruits
Abstract: The present investigation was aimed at exploring the anti-arthritic activity of ethanolic extract of Helicteres isora fruits, using Bovine serum albumin (BSA) and Egg albumin denaturation method. The extract was subjected to preliminary phyto-chemical screening in order to find out the major phyto-constituents present in it. Various concentrations of the extract (100, 250, and 1000 μg/ml) were prepared and the percentage inhibition of protein denaturation was determined. Diclofenac sodium (100, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 1, 2020 · pp. 34–40 Read article
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Medicinal Potential of Cullen corylifolium in Ageing and Ageing Related Diseases
Abstract: Cullen corylifolium is a tropical medicinal plant of the Fabaceae family, generally known as Babchi/Bakuchi in various regions of Asia. Cullen corylifolium is a traditional phyto-therapeutic plant of China used to manifest various pathological conditions since ages, possesing round and dark brown seeds with a rough texture. Cullen corylifolium has been previously reported to possess various properties such as antioxidant, anti-inflammatory and can be used as a solution to treat …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 21–32 Read article
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Variation in Extract Yield in Different Parts of Albizia lebbeck
Abstract: Phytochemical screening is an important step which leads to the isolation of new and novel compound. Solvent extract of the plant material with the help of different solvent such as n-hexane, chloroform, alcohol and aqueous revealed that in alcohol and aqueous solvent maximum extract yield obtained in all studied parts. Phytochemical screening analysis of the extract revealed presence of tannins, phenolics, flavonoids, alkaloids, terpenes and steroids in most parts. In …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 2, 2014 · pp. 1–5 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 27–40 Read article
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Antimicrobial Potential of Methanolic Extract of Barringtonia acutangula (L.) Gaertn Fruits
Abstract: Barringtonia acutangula is a middle-sized plant which is distributed in Meghalaya, Assam, West Bengal, Madhya Pradesh, Bihar and Odisha, used in treatment of various ailments. The present work has investigated the antimicrobial activity of methanol extract of Barringtonia acutangula fruit against six resistance bacterial strains such as Enterococcus faecalis, Staphylococcus aureus, Acinetobacter bumannii (Gram positive) and Citrobacter freundii, Enterobacter aerogenes, Escherichia coli (Gram negative). The antibacterial activity was evaluated by …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 3, 2016 · pp. 13–18 Read article
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Phytochemical Study of Seed Extract of Phaseolus vulgaris
Abstract: Phaseolus vulgaris L. is usually known as kidney beans. It is a green medicinal plant that has a place with the family Fabaceae. Conventional arrangement of medication utilized this for the cure of few sicknesses such as diabetes, malignant growth, kidney issues, and so forth. For the present research work, the powdered plant seeds were dissolved consecutively in various solvents in increasing polarity order. Different phytoconstituents such as saponins, flavonoids, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 3, 2020 · pp. 11–16 Read article
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Molecular Mechanism of Fluoride Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Fluorine (Fl) a member of the halogen family is the most electronegative and reactive of all the elements of the Periodic table. Chronic and acute exposures of fluoride leads to cardiovascular disease (hypertension and atherosclerosis), neurological disorders, gastrointestinal disturbances, liver disease, renal disease, reproductive effects, other health disorders and also affects the antioxidant system in the body. Furthermore, reactive oxygen species (ROS)-mediated oxidative damage is a common malady in fluoride …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 7–34 Read article
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Phytochemicals And Antioxidants Properties of Zanthoxylum zanthoxyloides Root Bark
Abstract: There have been studies on Zanthoxylum zanthoxyloides (Orinata), family; Rutaceae, which has shown remarkable benefits of the plant to humans traditional medicine. Root or stem bark macerations, decoctions or infusions of the plant are widely taken to treat malaria, fever, sickle cell anemia, tuberculosis, paralysis, oedema and general body weakness. They are also widely taken to treat intestinal problems, including colic, dysentery, intestinal worms, gonorrhea and urethritis. Studies show that …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 13, Issue 2, 2022 · pp. 23–28 Read article
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Rotenone Beyond Just An Insecticide: A Review
Abstract: Pesticides have received the most attention due to their global application and widespread implications on human health. In recent years, both epidemiological and toxicological studies have provided evidence that pesticides have the potential to act as toxicants contributing to the development of pathogenesis such as neuronal degenerations as well as may be utilized to induce signalling for reversal, suppress or prevent carcinogenic progression. Rotenone, an isoflavones naturally found in the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 8–13 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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A Review on Phytochemistry and Pharmacology of Macaranga peltata
Abstract: Macaranga peltata, categorized within the Euphorbiaceae family, represents a prevalent pioneer arboreal species across Southeast Asia, specifically in regions such as India and Sri Lanka. This review scrutinizes the phytochemical properties and pharmacological profiles of Macaranga peltata, underscoring both its historical medicinal applications and prospective therapeutic roles. The plant exhibits a rich composition of secondary metabolites, encompassing flavonoids, stilbenes, tannins, and terpenes, with the majority of these compounds being extracted …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 50–59 Read article