Search
159 articles for “Computational methods”
-
Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
-
Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
-
Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
-
Wireless Sensor Network Localization Based on Static Anchor Node
Abstract: Anchor-based localization is a crucial challenge in wireless sensor networks (WSNs), aiming to determine the positions of all sensors by leveraging a limited number of anchor nodes whose locations are known. In this paper, we propose a novel algorithm for anchor-based localization in a static network, which improves the localization accuracy while reducing the computational complexity compared to existing methods. Our algorithm uses a range-based approach to estimate the distances …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 1, 2023 · pp. 12–20 Read article
-
Thermal Steganography: A New Way to Steal Data from Air-Gapped Computers Using Heat and Fan Noise
Abstract: Nowadays, high-security computers are "air-gapped," meaning they are not connected to the internet to prevent hacking. Cybercriminals are increasingly using direct, physical methods to access and take data instead of relying on internet-based attacks. This paper introduces a new cybersecurity threat called Thermal-Secret. Most existing heat-based attacks are very slow and fail if the room temperature changes. To solve this, we developed a Slope-Based method. Instead of looking at how …
Published in International Journal of Information Security Engineering · Vol. 4, Issue 2, 2026 Read article
-
Parallel Greedy Approach for Phylogenetic Tree Construction in the Context of Marine Species
Abstract: The rebuilding of phylogenetic trees for marine species shows major computing problems because of the massive genomic data and the huge biodiversity inherent in ocean ecosystems. Traditional phylogenetic methods are accurate but become more expensive when they are processing with thousands of marine taxa parallelly. This article shows a critical analysis of parallel greedy algorithms as an adaptable solution for large-scale marine phylogenetics. It examines the main principles of greedy …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 1, 2026 · pp. 33–45 Read article
-
The Role of AI in Modern Healthcare Systems
Abstract: In the Indian pandemic, several issues in the healthcare system have brought to the forefront the imperative of hospitals shifting from manual medical records to computerized healthcare information systems. These solutions offer an effective method for integrating computer-based decision support tools and communicating e-healthcare information. With increasing dependence on AI-based solutions, a strong IT infrastructure is essential for improving healthcare quality, data security, and controlling increasing medical expenses. Advances in …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 69–76 Read article
-
Effects of Cluster Computing on Big Data Analysis and Network Topology
Abstract: The rapid expansion of big data has posed substantial difficulties for conventional computing systems. As a result, cluster computing has grown to be a potent method for effective large data processing. Cluster computing involves multiple interconnected nodes functioning as a unified system, pooling together their processing, storage, and memory resources. These nodes are typically connected through high-speed networks such as ethernet or InfiniBand, facilitating efficient data sharing and communication among …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 31–39 Read article
-
In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
-
Overview of Ionic Polarization: A Model Based Novel Approach
Abstract: This study presents a comprehensive analysis of ionic polarization through a novel model-based approach that integrates theoretical, computational, and experimental methodologies. Ionic polarization, which significantly influences the dielectric properties of materials, is examined through the lens of the Clausius-Mossotti equation and the Debye relaxation model, providing a theoretical framework for understanding the relationship between ionic displacement and dielectric behavior. To explore ionic displacement and polarization at the atomic level, advanced …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 18–25 Read article
-
Optimized Sentiment Analysis Through TextBlob and Hybrid RNN Models
Abstract: In today’s world, analyzing people’s feelings from what they write online has become very important. This is because there is a large amount of content created by users. To make this analysis accurate and fast, we present a method. This method uses a mix of two approaches: one that looks up words in a dictionary and another that uses computer learning. TextBlob is an affordable tool for getting an initial …
Published in International Journal of Computer Science Languages · Vol. 4, Issue 1, 2026 · pp. 29–28 Read article
-
Advanced Computational Models for Predicting Molecular Interactions
Abstract: Understanding molecular interactions is essential for a number of disciplines, including biochemistry, materials science, and medication development. Traditional experimental methods, while accurate, are often time-consuming and expensive. Advanced computational models have emerged as powerful tools to predict molecular interactions efficiently. In order to predict the behavior and interactions of molecules at the atomic and subatomic levels, this paper reviews the most recent developments in computational techniques, such as machine learning …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 8–13 Read article
-
Fracture Analysis of Laminated composite plates using Extended Finite Element Method: A Review
Abstract: Laminated composite plates are used in aerospace, automotive, and marine industries. They feature great durability against fatigue, a high strength-to-weight ratio, and mechanical attributes that may be altered. However, they are prone to fracture and delamination under complex loading, requiring accurate fracture analysis for structural integrity. Traditional finite element methods (FEM) need extensive mesh refinement for modelling crack propagation which increases the computational costs. The Extended Finite Element Method (XFEM) …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 16–25 Read article
-
A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
-
An Investigative Study of Quantum-safe Secure Multi-party Computation
Abstract: This article represents the comprehensive investigation in the emerging field of quantum-safe secure multi-party computation (QSSMPC) and presents novel perspectives to address the impending threat posed by quantum computers to classical cryptographic systems. As the era of quantum computing approaches, traditional encryption methods become vulnerable to quantum algorithms, necessitating the development of quantum-resistant cryptographic protocols. In this context, the paper introduces innovative approaches to secure multi-party computation in a quantum-safe …
Published in International Journal of Computer Science Languages · Vol. 2, Issue 1, 2024 · pp. 39–44 Read article
-
Deep Learning Enhanced Compressive Sensing for Wireless IoT Data Optimization and Weather Monitoring.
Abstract: This research explores the application of deep learning and compressive sensing in order to optimize data traffic in non-orthogonal multiple access (NOMA)-based wireless internet of things (IoT) networks and weather monitoring. Such a framework would be very effective and overcome pilot attacks and reconstruction losses for secure data transmission. In this regard, a strong communication model has been adopted based on power-domain NOMA for simultaneous wireless transmission by multiple IoT …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 2, 2024 · pp. 20–36 Read article
-
Deep Learning-Based Thermal Prediction Models for Solid-State Electronic Devices
Abstract: The rapid advancement of solid-state electronic devices in high-performance computing, communication systems, automotive electronics, and renewable energy applications has significantly increased concerns related to thermal management and device reliability. Excessive heat generation in semiconductor devices adversely affects operational efficiency, switching performance, lifespan, and overall system stability. Traditional thermal prediction methods often require complex numerical computations and extensive simulation time, making them less suitable for real-time monitoring and adaptive control applications. …
Published in International Journal of Solid State Innovations & Research · Vol. 4, Issue 1, 2026 Read article
-
Design and Simulation of Low-power, High-speed Effective Area Mux Based One-bit Full Adder Using CMOS Technology
Abstract: Our findings reveal a novel kind of circuit capable of performing both XOR and XNOR operations in parallel. Power dissipation and delay are both greatly reduced in the proposed circuits due to their low output capacitance as well as minimal short-circuit power dissipation. We show six new hybrid 1-bit full-adder (FA) circuits that take use of the XOR-XNOR or XOR/XNOR gates' special full-swing function. Each potential circuit layout has both …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 1, 2023 · pp. 25–33 Read article
-
A Study to Assess the Stress and Anger Management by Deep Breathing Exercise and Meditation Among Adolescent Nursing Students at a Selected Nursing School in Delhi
Abstract: Introduction: Stress is a response that can lead to physical, emotional, or psychological strain. It is a frequent occurrence in daily life. Stress acts as the body's natural mechanism for defense against potential threats and dangers. It initiates a release of hormones that ready the body's functions to either confront danger head-on or retreat, commonly known as the fight-or-flight reaction. Anger can be caused by both external and internal events …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 15–19 Read article
-
Progress and Uses of Satellite Remote Sensing
Abstract: Satellite remote sensing has become an important tool for watching, studying, and controlling both natural and man-made systems on Earth. Satellite sensors collect electromagnetic radiation that is reflected or transmitted from the Earth's surface. This data is needed for environmental monitoring, resource management, and hazard assessment. Recent improvements in sensor resolution, data processing techniques, and cloud-based platforms have made remote sensing applications much more accurate and easier to use. The …
Published in International Journal of Satellite Remote Sensing · Vol. 3, Issue 2, 2025 · pp. 8–19 Read article