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431 articles for “Signalling”
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Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
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Experimental and Numerical Investigation of Corrosion-Induced Failures in Copper-Tin Alloy (Cu-Sn) and Aluminum-Magnesium Alloy (Al-Mg) Connectors: A Stress–Corrosion Coupling Analysis
Abstract: The utilization of an integrated experimental and finite element modelling (FEM) methodology, this study investigates the degradation and failure mechanisms in polymer composite electrical connectors exposed to aggressive environmental conditions. Epoxy- and polyamide-based composites, reinforced with carbon and glass fibers, were subjected to accelerated salt spray and humidity–temperature cycles to simulate prolonged outdoor exposure. Electrochemical and environmental aging experiments revealed that chloride ions and moisture ingress were responsible for matrix …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 366–379 Read article
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Automatic Coffee Making Machine Using Verilog HDL
Abstract: This Paper focuses on the design and implementation of a Coffee Machine using Verilog, aimed at understanding how real-life machines can be controlled using digital logic. In daily life, a coffee machine works by taking user inputs, processing them, and giving the required output such as preparing coffee. The main objective of this project is to design a simple digital system that controls the basic working of a coffee machine. …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 1, 2026 · pp. 18–24 Read article
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An Overview on Quantum dot technology in Temperature sensor design
Abstract: Quantumdot (QD) thermometry harnesses the sizedependent electronic structure of semiconductor nanocrystals to translate minute temperature variations into robust optical signals. In this work we present a systematic design framework for QDbased temperature sensors that integrates (i) bandgap engineering through precise colloidal synthesis, (ii) surfacestate passivation to suppress nonradiative pathways, and (iii) a planar photonicreadout architecture compatible with lowcost, CMOSfriendly fabrication. By exploiting the linear redshift of the photoluminescence (PL) peak …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 1, 2026 · pp. 10–17 Read article
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Design & Implementation of 16-BIT MAC Unit Using Vedic Mathematics
Abstract: Multiply and Accumulate (MAC) units are essential parts of digital systems, particularly in embedded systems, digital signal processing (DSP), and image processing. The performance of these systems is significantly impacted by how well the multiplication process works. The design and construction of a fast 16-bit MAC unit utilizing Vedic mathematics are presented in this study.The proposed design utilizes the Urdhva Tiryagbhyam sutra to perform multiplication in a parallel manner, reducing …
Published in Journal of VLSI Design Tools and Technology · Vol. 16, Issue 1, 2026 · pp. 52–58 Read article
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The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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Marine Microbial Ecology: A Comprehensive Review of Interactions, Symbiosis, and Bioprospecting.
Abstract: Marine microorganisms constitute the largest and most dynamic fraction of Earth's biodiversity, governing vital ecosystem functions ranging from global biogeochemical cycling to host-specific symbiotic associations. This review provides a comprehensive synthesis of the complex interaction networks within marine microbial communities. We first explore the theoretical foundations of microbial niche construction and evolutionary dynamics in the ocean. Subsequent sections dissect micro-scale interactions within the phycosphere, where chemical gradients dictate cross-kingdom mutualisms …
Published in International Journal of Marine Life · Vol. 3, Issue 1, 2026 · pp. 6–16 Read article
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Image Compression via Non-separable Discrete Fractional Fourier Transform
Abstract: The main idea behind image compression is to reduce the bandwidth for transmission and required space for storage. Thus, image compression is of great importance. In this paper we present the image compression technique using Non-Separable Discrete Fractional Fourier Transform (NSDFrFT). Numerical simulation results suggested that image compression method using NSDFrFT as transform technique gives better performance for images when compression ratio is high in comparison to DFrFT and JPEG. …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 2, Issue 3, 2015 · pp. 1–9 Read article
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A Comprehensive Review of Ethnobotanical Studies on Traditional Indian Herbal Plants for Lung Cancer Management
Abstract: Lung cancer is a leading cause of cancer-related deaths in the world. Current therapies for lung cancer are often limited by many side effects. This review compiles and evaluates ethnobotanical evidence and modern scientific findings of Indian herbal plants traditionally used for respiratory and tumor-related disorders, with a focus on their relevance to lung cancer management. Herbal phytochemicals and how they show their potent activities were also listed in this …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 1–7 Read article
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Deep Learning for Real-Time Monitoring and Defect Detection in Additive Manufactured Polymer Composites
Abstract: Additives Fiber-reinforced polymer composite ADDs have high utility in making lightweight structural components, but due to process-related defects (interlayer delamination and reinforcement stacking) the integrity of consolidation during extrusion-based deposition is frequently compromised. This paper has presented a physics-informed deep learning framework that is applicable to real-time measurements of reinforced thermoplastic composite fabrication. Multimodal sensing was provided with thermal gradient, optical morphology, and acoustics emission signals being used to assess …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 974–999 Read article
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IoT-Based Structural Health Monitoring and Damage Detection in Fiber Reinforced Polymer Composite Structures
Abstract: Applications of fiber-reinforced polymer (FRP) composite in the aerospace, civil infrastructure and renewable energy systems are increasing due to the fact that the composite possesses high ratio of strength to weight and can resist corrosion. However, processes of internal damages such as the cracking of the matrix, delamination and fiber fracture, are likely to take place without being visible on the surface and therefore a periodic check of the structure …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1076–1100 Read article
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Gesture Controlled Chair
Abstract: The Gesture Controlled Chair is a state-of-the-art assistive device that allows users to control the movements of their wheelchair with ease and efficiency using hand gestures. The existing technologies for controlling wheelchairs have been manual controls that require a certain level of physical strength, making them less suitable for elderly patients or those with physical disabilities. In this regard, a gesture-controlled interface was introduced as an alternative to the existing …
Published in International Journal of Electronics Automation · Vol. 4, Issue 1, 2026 Read article
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A Technical Blueprint for AI-Driven Localization in 6G Mobile Networks
Abstract: The advent of sixth-generation (6G) wireless systems promises unprecedented spatial resolution, ultra-low-latency, and pervasive connectivity, turning mobile localization from a peripheral service into a core enabler of immersive extended reality (XR), autonomous logistics, and digital twins. Yet, the sheer scale of dense terahertz (THz) deployments, the stochastic nature of reconfigurable intelligent surfaces (RIS), and the dynamic interference landscape render traditional model-based positioning techniques inadequate. This work investigates how artificial intelligence …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 13, Issue 1, 2026 · pp. 26–34 Read article
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An Overview on Microwave Remote Sensing for Earth Observation
Abstract: To understand the Earth from space, one must look beyond the visible eye. While optical satellites rely on the Sun’s reflection much like the human eye they are frequently blinded by the curtain of cloud cover, smoke, or the dark veil of night. To bypass these limitations, we turn to Microwave Satellite Sensing. By utilizing electromagnetic waves with wavelengths ranging from 1 millimeter to 1 meter, we can see through …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 1, 2026 · pp. 21–25 Read article
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An Overview on Harnessing Microwave Frequencies for Next-Generation Satellite Communication and Earth Observation
Abstract: In the vacuum of space, where traditional cables cannot reach, humanity has woven an invisible, high-speed infrastructure made of oscillating electromagnetic waves. At the heart of this architecture lies the microwave spectrum—the unsung hero that enables everything from global GPS navigation to real-time climate monitoring. The evolution of global connectivity and environmental monitoring is intrinsically linked to the mastery of the microwave spectrum. As satellite constellations transition from traditional Geostationary …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 1, 2026 · pp. 1–6 Read article
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From High-Resolution Optics to High-Bandwidth Telemetry: The Evolution of Deep-Space Imaging Satellites
Abstract: The development of deep space imaging satellites has significantly enhanced satellite communication and space exploration capabilities. Earlier satellite systems relied on low-resolution imaging and conventional radio-frequency (RF) communication, which limited data transmission rates and image quality. With advancements in technology, modern satellites are equipped with high-resolution optical systems capable of capturing detailed images of celestial bodies. Furthermore, the introduction of high-bandwidth telemetry systems, such as Ka- band and optical (laser) …
Published in Trends in Opto-electro & Optical Communication · Vol. 16, Issue 1, 2026 · pp. 34–40 Read article
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Modern Chemistry & Chemical Technology in Sensor Formation
Abstract: The field of sensor formation stands at the vibrant intersection of modern chemistry and chemical technology, driven by an insatiable demand for precise, rapid, and sensitive detection across myriad applications. This paper explores the foundational and transformative role these disciplines play in engineering next-generation sensing platforms. Modern chemistry, through its atomic-level precision in synthesizing novel responsive materials – ranging from advanced polymers and supramolecular architectures to cutting-edge nanomaterials like graphene, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 1–9 Read article
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Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Thin Film Technology in Sensor Manufacturing – A Technical Discussion
Abstract: Thin‑film technology has become the cornerstone of modern sensor manufacturing, enabling the convergence of miniaturisation, multifunctionality, and cost‑effective mass production. This paper surveys the latest advances in deposition techniques—ranging from magnetron sputtering and chemical vapour deposition to atomic‑layer deposition (ALD) and ink‑jet‑printed sol‑gel processes—and examines how their unique material‑control capabilities translate into performance gains across the sensor spectrum (chemical, physical, and bio‑sensing). By integrating nanoscale thickness control (≤ 10 nm) …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 13, Issue 1, 2026 · pp. 48–58 Read article
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Design of an ArUco Marker-Guided Smart Trolley with Integrated Billing Estimation
Abstract: The growing adoption of automation in retail environments has increased the need for intelligent systems that improve user convenience and reduce manual effort. This paper presents the design and development of a human-following smart shopping trolley with an integrated automatic billing system based on computer vision. The proposed system employs ArUco marker–based human tracking to achieve reliable and real-time following behaviour. A Raspberry Pi serves as the central processing unit, …
Published in Journal of Mechatronics and Automation · Vol. 13, Issue 1, 2026 Read article