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474 articles for “Clinical study”
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MIRDcalc & OLINDA/EXM Dosimetry Software Analysis by SPECT/CT Scan Data of Lu-177 DOTATATE Radionuclide Therapy of NET Patients
Abstract: Accurate dosimetry is essential in nuclear medicine for optimizing radionuclide therapies and ensuring patient safety. In Radiopharmaceutical dosimetry the Medical Internal Radiation Dosimetry (MIRD)Society is the pioneer in organ-level dosimetry providing the fundamental basis for commonly used clinical and research dosimetry software like MIRDOSE and OLINDA/EXM. Recently, in MIRD Pamphlet No. 28, Part 1, the MIRD committee of the Society of Nuclear Medicine and Medical Imaging presented a new Software …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 48–63 Read article
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Therapeutic Potential of Plant-Derived Phytochemicals in Targeting Receptor Pathways Related to Non-Enzymatic Glycation: A Meta-Analysis
Abstract: Background: Non-enzymatic glycation, where reducing sugars react with proteins, lipids, and nucleic acids, contributes to various pathological conditions, such as diabetic complications and cardiovascular diseases. This process is facilitated by the receptor for advanced glycation end-products (RAGE), which is pivotal in driving inflammation and causing tissue damage. Objective: This meta-analysis evaluates the effects of plant-derived phytochemicals on RAGE expression and associated signaling pathways, assessing their therapeutic potential in glycation-related diseases. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 60–73 Read article
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Bal Ex Module with Prayer Regimes Improves Standing Dynamic Balance of balance disorders cases
Abstract: Integrating prayer regimes into balance rehabilitation, a well-established approach for patients with balance disorders offers an intriguing dimension to the therapy that had been incorporated in this Bal Ex Homebased video module for balance rehabilitation. Vestibular rehabilitation, often exemplified by Cawthorne-Cooksey exercises and their customized variants, effectively addresses symptoms like vertigo and instability. However, it's important to approach the inclusion of spiritual practices with sensitivity, acknowledging patients' diverse beliefs and …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 10–14 Read article
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Zika Virus: Long-term Effects and Vaccine Development Efforts
Abstract: Zika virus (ZIKV) is a mosquito-borne flavivirus that gained international concern following the 2015-2016 outbreak in the Americas. Although most ZIKV infections are asymptomatic or mild, the virus presents significant public health risks due to its ability to cause severe neurological complications, especially in pregnant women and their offspring.Congenital Zika Syndrome (CZS) encompasses a range of fetal abnormalities, including microcephaly, vision impairment, hearing loss, and developmental delays. Infants exposed to …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 25–28 Read article
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High-Definition Electroencephalography: A New Horizon in Neurological Pathology Research
Abstract: The advent of high-density electroencephalography (HD-EEG) has catalyzed a paradigm shift in the exploration of neurological pathologies. This editorial underscore its transformative potential in elucidating brain dynamics and refining diagnostic approaches for a spectrum of conditions, spanning from epilepsy and dementia to cognitive impairments in preterm infants. Our objective is to optimize the utility of HD-EEG by emphasizing the imperative for methodological homogenization and fostering collaborative endeavors. The remarkable spatial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 15–21 Read article
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Post Halela Zard (Terminalia chebula Retz.): A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Halela Zard (Terminalia chebula Retz.), commonly known as Haritaki in Sanskrit and Chebulic Myrobalan in English, is a cornerstone of Unani pharmacotherapy due to its remarkable therapeutic versatility. The dried pericarp of its fruit has been extensively employed in traditional medicine for the treatment of a wide spectrum of ailments, ranging from digestive disturbances to chronic systemic disorders. This review aims to present a comprehensive overview of Halela Zard by …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 19–26 Read article
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Hakim Ismail Jurjani (1042–1137 AD): Life, Works, and Medical Legacy
Abstract: Hakim Ismail Jurjani, also known as Seyyed Isma’il Jorjani, was among the most distinguished physicians and scholars of medieval Persian medicine whose contributions significantly influenced the development of Greco-Arab and Unani medical traditions. His monumental encyclopedia, Zakhīra Khwārazmshāhī (Treasure of the Khwarazm Shah), is regarded as one of the greatest medical compilations of the Islamic Golden Age and represents a landmark in the evolution of Persian scientific literature. Unlike earlier …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Dr. Somenath Dutta, Discoverer of Micro-RNA (MiRNA) Therapeutic to Prevent Harmful Zika Virus for Liver Cancer: A Scientometric Portrait
Abstract: Dr. Somenath Dutta allies Rahul is a global recognized scientist for his outstanding recent discovery of “miRNA therapeutics for the Zika virus” at the age of 26 years, which can be cured Liver Cancer and allied health problems due to Zika virus disease. This study covers his 12 publications in variety of forms including 07 journal articles (59%), 03 conference papers (25%), 01 dissertation, and 01-chapter paper during 2019-2024. All …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 22–36 Read article
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Comparative Analysis of the Structural Integrity and Dimensional Stability of Additively Manufactured Biopolymers vs. Thermoformed PETG: A 1-Year Retrospective Study on Polymer Performance in Orthodontic Applications
Abstract: Objective: This study aimed to evaluate the long-term dimensional accuracy and structural performance of direct 3D-printed biopolymers compared to conventional vacuum-formed Polyethylene Terephthalate Glycol (PETG) composites. The investigation focused on how different polymer processing methods (additive manufacturing vs. thermoforming) influence material thinning and resistance to occlusal stress. Methods: A retrospective analysis was conducted on 60 cases (n = 60) of post-orthodontic maintenance. The sample was divided into two cohorts: Group …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 140–146 Read article
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Nature’s Pharmacy: Plant-Based Antifungal Agents and Their Therapeutic Potential
Abstract: Antifungal resistance has increased dramatically over the last 10 years, causing serious problems for healthcare because of higher morbidity and death. The urgent need for new treatments is highlighted by the scarcity of effective antifungal medications, their toxicity, and the rise of resistant strains. Since many plants have bioactive secondary metabolites with strong antifungal qualities, including alkaloids, flavonoids, terpenoids, phenolics, and saponins, ethnobotanical sources offer a viable path. Plants with …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Red Cell Distribution in Pregnancy Associated with Preeclampsia Patients in Worldwide: A Brief Review
Abstract: Introduction: Preeclampsia (PE) is a major obstetric problem contributing considerably to maternal and prenatal morbidity and mortality worldwide. Preeclampsia varies in incidence in India from 5% to 15%. The role of this hematological parameter in clinical assessment, differential diagnosis, and prognosis evaluation of PE remains unclear. Thus, the purpose of the current review was to investigate the red cell distribution width (RDW) in preeclampsia, analyze its importance for early diagnosis, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 6–12 Read article
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The Impact of Quran Memorisation on Wellbeing: Lived Experiences of Bohra Huffaz
Abstract: The Quran, revealed over 1400 years ago, remains central to Muslims' daily lives, particularly through recitation during prayers. Quran memorisation (QM), known as Hifz, is a centuries-old tradition requiring intense cognitive engagement, discipline, and spiritual dedication. While many studies explore the psychological benefits of spiritual practices, few have examined the profound impact of full Quran memorisation on personal well-being. This study examines how Quran memorisation influences psychological well-being, particularly among …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 1–13 Read article
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Frequency of Failed Spinal Anesthesia and Associated Factors in Cesarean Section at Mardan Medical Complex, Mardan, KP, Pakistan
Abstract: Objective: Spinal anesthesia is the preferred choice of anesthesia for parturients having cesarean sections. Despite the high percentage of success in providing acceptable surgical anesthesia, failure of spinal anesthesia has been reported. This study aims to determine the frequency and associated factors related to failed spinal anesthesia during cesarean sections in pregnant women. Methodology: This descriptive cross-sectional study included 149 pregnant women and was conducted at Mardan Medical Complex (MMC) …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Breakthroughs in Biotechnology for the Regulation of Infectious Diseases
Abstract: Infectious diseases have a heavy impact on both public health and the world’s economies. In most diseases, antibiotic resistance has become widespread over time. A variety of diseases comprising pneumonia, tuberculosis, and gonorrhea go through the same evolutionary processes, which include the formation of drug-resistant pathogens in response to selection pressure from medications and their potential extinction when drug use is ceased. Since the occurrence of drug resistance in serious …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 1–25 Read article
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Photonic Diagnostics: Harnessing Optical Sensing for Non-Invasive Assessment of Coronary Obstruction
Abstract: Cardiovascular diseases (CVDs) remain the leading cause of mortality globally, with coronary artery blockages primarily atherosclerosis representing a critical challenge. The gold standard for diagnosing coronary artery disease remains invasive coronary angiography, a procedure that, while precise, carries inherent patient risks, high costs, and logistical burdens. Optical sensors, leveraging the principles of light-tissue interaction, offer real-time, high-resolution insights into vascular health, paving the way for early detection of arterial stenoses …
Published in International Journal of Optical Innovations & Research · Vol. 4, Issue 1, 2026 · pp. 25–30 Read article
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Butrin Tackles Retinoblastoma – A Clinical Hypothesis †
Abstract: Breach of association of legumain protein activities to the corresponding cellular components results in over-expression of legumain, and constitutes a key biomarker for a variety of life-taxing sicknesses like cancer, Alzheimer’s/Parkinson’s and acute kidney injury. To suppress the functions of legumain, it is hypothesized that a water soluble and edible biomolecule, namely, butrin (7, 3’, 4’-trihydroxy flavanone-7, 3’-diglucoside) may have the therapeutic potential owing to its special ability to bind …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 26–30 Read article
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Construction and Standardization of Beauty Satisfaction Scale for Adolescents with Cleft Lip and Palate
Abstract: This study outlines the methodology and findings of a study that aimed to create a tool for assessing adolescents with oral facial clefts’ levels of beauty satisfaction. The development of this tool includes a well-detailed literature survey, focus group discussion with adolescents with oral facial clefts, and the wide process of consultation with the cleft surgeon, orthodontist, pediatrician, and clinical psychologist. Further test construction includes planning of the scale, item …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 19–23 Read article
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A prospective investigation into seroma monitoring and skin flap anchoring following Mastectomy
Abstract: Breast cancer remains a significant global health challenge, often necessitating life-saving mastectomy surgeries. However, post-mastectomy complications—such as seroma formation and skin flap necrosis—can still impact a patient’s recovery and overall quality of life. This prospective study examines the effectiveness of seroma monitoring and skin flap anchoring following mastectomy in reducing these problems. Few prospective studies addressing these particular concerns were found in a thorough literature assessment. To fill this void, …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 Read article