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837 articles for “Clinical”
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Sustainable Advances in Oral Pathology: The Impact of Artificial Intelligence
Abstract: Oral cavity cancers constitute about 4% of all malignant neoplasms. More than 9,900 new cases are reported from the developed countries yearly, and the 5-year mortality rate is higher than 39%. In Europe, the highest rates occur in Hungary, Croatia, and other Central and Eastern European countries; high levels are also seen in India, Pakistan, and Bangladesh. The management of endosseous pathologies presents considerable challenges because they often exhibit no …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 24–27 Read article
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Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
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Revolutionizing oncology - role of artificial intelligence in early cancer detection and diagnostic advances-A comprehensive review
Abstract: Oncology has experienced a remarkable transformation with the adoption of artificial intelligence (AI), which has greatly enhanced cancer detection and diagnosis. As one of the leading causes of death worldwide, cancer highlights the importance of early detection in improving patient outcomes and survival rates. AI’s ability to analyze vast and complex datasets has enabled groundbreaking innovations in imaging, pathology, biomarker discovery, and predictive analytics. This review highlights key AI-driven advancements …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 18–22 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Harnessing Honeybee Venom For Cancer Treatment: A Natural Remedy In Oncology
Abstract: Honeybee venom (HBV) has harvested significant attention as a promising natural compound with therapeutic potential in cancer treatment. This review investigates deeply into the current scientific understanding of honeybee venom, focusing on its anticancer mechanisms, molecular interactions, and potential clinical applications. Honeybee venom comprises various bioactive components, including melittin, apamin, phospholipase A2, and other peptides, which exhibit a wide range of biological activities. Recent research has demonstrated its ability to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 10–14 Read article
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The Contribution of A. I. in Pharmaceutical Software
Abstract: The integration of Artificial Intelligence (AI) in pharmaceutical software has significantly transformed drug development, regulatory processes, and clinical management. AI-powered tools are revolutionizing data analysis, predictive modeling, and decision-making, enhancing the efficiency and accuracy of drug discovery and development. This article explores the multifaceted contributions of AI to pharmaceutical software, including its applications in drug screening, personalized medicine, clinical trial optimization, and regulatory compliance. Additionally, we examine how AI is …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Excoecaria agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies
Abstract: Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
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Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
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Unmasking Human Metapneumovirus: The Emerging Threat to Vulnerable Populations
Abstract: Human Metapneumovirus (HMPV) is a contagious respiratory virus that commonly spreads among individuals. It can cause serious infections, especially in high-risk groups like infants, older adults, and individuals with weakened immune systems.It is a major contributor to acute respiratory illnesses. Since its discovery in 2001, HMPV has been identified as a common cause of both upper and lower respiratory tract illnesses, with clinical presentations ranging from mild symptoms to severe …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 16–24 Read article
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Zika Virus: Long-term Effects and Vaccine Development Efforts
Abstract: Zika virus (ZIKV) is a mosquito-borne flavivirus that gained international concern following the 2015-2016 outbreak in the Americas. Although most ZIKV infections are asymptomatic or mild, the virus presents significant public health risks due to its ability to cause severe neurological complications, especially in pregnant women and their offspring.Congenital Zika Syndrome (CZS) encompasses a range of fetal abnormalities, including microcephaly, vision impairment, hearing loss, and developmental delays. Infants exposed to …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 25–28 Read article
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Navigating the Spectrum of Patient Care: A Comprehensive Approach
Abstract: In the ever-evolving landscape of healthcare, providing optimal patient care demands a multifaceted approach that spans across diverse dimensions. “Navigating the Spectrum of Patient Care: A Comprehensive Approach” delves into the intricacies of modern healthcare delivery, offering insights into the myriad factors that influence patient outcomes. This comprehensive analysis encompasses various aspects, including clinical expertise, technological advancements, patient engagement strategies, ethical considerations, and healthcare policy implications. By examining the intersections …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 1, 2025 · pp. 28–34 Read article
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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A Community Awareness Project on Monkeypox (Mpox) and Enhanced Nursing Care for Patients: A Comprehensive Review
Abstract: Monkeypox (Mpox), a rare viral infection transmitted from animals to humans by the monkeypox virus, has attracted increasing attention due to its ability to spread between humans and its clinical similarities to other poxvirus diseases, including smallpox and chickenpox. Enhancing nursing care for monkeypox patients is imperative to manage and contain its spread effectively. On 15th October 2024, B.Sc. Nursing Interns of Holy Family College of Nursing, University of Delhi, …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 11–15 Read article
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Comprehensive Evaluation of Herbal Plants for Cancer Prevention
Abstract: Since cancer continues to be a major cause of morbidity and death globally, effective prevention measures are desperately needed. As the world’s cancer burden increases, interest in alternative cancer prevention methods, particularly the use of herbal medicine, is also increasing. With their rich history and diverse phytochemical composition, medicinal plants provide a great opportunity for the development of disease prevention strategies. This review explores the potential of various plants, including …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Machine Learning-Based Approach for Heart Disease Prediction
Abstract: Heart disease is a significant global health challenge, with early diagnosis and prediction being essential for reducing mortality rates. Machine Learning (ML), an efficiently developing field within Artificial Intelligence, provides innovative methods for analyzing complex clinical data to predict heart disease. This review examines the basic machine learning techniques, data, and metrics used in cardiovascular disease prediction. It explores the role of supervised learning, such as decision trees and logistic …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 64–73 Read article
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Artificial Intelligence in intra operative and peri operative management of major oral and maxillofacial surgeries
Abstract: Artificial Intelligence and virtual reality are becoming a part of everyday life and are enhancing our quality of life extensively. It is only natural that the same shall be used in surgery also. The existing body of literature on artificial intelligence (AI) and its integration into various surgical specialties has been extensively reviewed and discussed in this article. These insights, though derived from broader surgical domains, can be effectively translated …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 2, 2025 · pp. 1–5 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
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Algorithm for the prediction of cardiovascular disease (CVD)
Abstract: cardiovascular diseases (CVD) still claim a significant number of deaths globally and remain the number one killer with an annual death toll of nearly 17.9 million. While several medical advancements have been made, an early diagnosis is still hard to obtain, which often leads to worsening conditions and intricate treatment options. With the advancement of modern technology, Machine learning has demonstrated to be a miraculous tool which can greatly impact …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article