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1499 articles for “1Alu (IL-6)”
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An AAV Vector for Inducible Gene Expression Preferentially in Muscles
Abstract: Adeno associated viral (AAV) vectors has been used widely in gene therapy and efforts have been made to improve their utility by adding genetic elements that would enable targeting transgene expression to particular cells or tissues of interest and permitting on/off regulation of expression. In this study, we designed a recombinant AAV9 variant PHP.eB vector with muscle creatine kinase (Mck)-derived enhancers, a synthetic muscle-expression promoter, in combination with a third-generation …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 46–61 Read article
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Effectiveness of Sensitization Program on Knowledge of School Children Regarding Refractive Errors
Abstract: The human eyes are portals of absorbing divine knowledge from the surrounding world. These two precious pearls need to take proper care throughout to taste life. The eye care starts right from birth onward and becomes keenly required in children's school age as they use these gifts for intense learning. The neglected care in the initial years may trouble them with various visual disorders and disturb their studies too. Well-structured …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 13–20 Read article
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A Study to Assess the Effectiveness of Video-assisted Teaching Programme on Knowledge Regarding Prevention and First Aid Management of Snakebite Among Mahatma Gandhi National Rural Employment Guarantee Scheme (MGNREGS) Workers in Selected Areas at Wayanad
Abstract: This study aimed to assess the impact of a video-assisted instructional program on the awareness of snake bite prevention and first aid practices among MGNREGS workers in Meppadi Panchayath, Wayanad. Using a quasi-experimental one-group pre-test post-test research approach, the study included 60 participants selected through convenient sampling. The participants' demographics revealed a varied distribution, with the majority falling within the 36–45 year age bracket (35%) and having an educational background …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 9–13 Read article
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Evaluating the Impact of a Structured Teaching Program on the Knowledge of Mothers with Children Under Five Regarding Upper Respiratory Tract Infections and Home Remedies in a Selected Primary Healthcare Area in Bengaluru
Abstract: Background: Upper Respiratory Tract Infections are contagious infections involving the nose, throat sinuses, pharynx, larynx, tonsils, and adenoids. The typical upper respiratory tract infections are nasopharyngitis (common cold), tonsillitis, sinusitis, laryngitis, and pharyngitis etc., Precautionary measures in early stages can help to prevent complications. Further, home remedies can offer comfort from symptoms and reduce the duration of illness and these home remedies have no side effects, but also boost up …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 14–19 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Evaluation of Prescribing Pattern of Drugs in Hemodialysis Patients
Abstract: Background: Patients undergoing hemodialysis often exhibit a high level of dependency and frequently present with multiple co-morbid conditions Chronic kidney disease (CKD) poses a significant global public health challenge, with its association with numerous complications. Prescribing medications appropriately for individuals with CKD presents a substantial challenge. Objective: The study aimed to assess the prescribing patterns of drugs in hemodialysis patients. Results: Out of the total 82 selected patients, 42 (51%) …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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Effects of Nano Additives on Performance and Emission Characteristics of CI Engine with Mahua Biodiesel and Diesel Blends as Fuel
Abstract: Due to growing environmental concerns and the imminent depletion of fossil fuels, the development of eco-friendly alternative fuels, such as biodiesel, is imperative. To improve the performance and emission properties of diesel engines utilizing biodiesel blends, the effective introduction of metallic and non-metallic nano-additives has been established. This research aimed to investigate the blending ratios of biodiesel (B0, B10, B20, and B40) in a compression ignition engine. Furthermore, the impact …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 41–49 Read article
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Development of an Innovative Nanotransdermal Formulation Utilizing an Optimal Combination of Acyclovir and Omeprazole to Improve Antiviral Efficacy
Abstract: The study effectively created nanogel formulations of Acyclovir and Omeprazole using the solvent diffusion technique. Among the various formulations (F1–F9), F9 was identified as the most suitable for gel preparation based on its pH evaluation. Drug content analysis, performed using UV-spectroscopy, confirmed the homogeneity of the prepared nanogels, which appeared opaque, free of lumps, particles, or aggregates. The spreadability assessment of F9 demonstrated excellent spreadability, while viscosity values for all …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 19–35 Read article
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Reusable Plastic Advantages, Challenges, and Impacts on Waste Management and Conservation Efforts
Abstract: The widespread utilization and ill-advised removal of single-use plastics have prompted critical natural contamination and asset consumption. Accordingly, society is progressively looking for supportable other options, with reusable plastic arising as a promising arrangement. This exploration paper intends to dig into the idea of reusable plastic, investigating its advantages, difficulties, and likely effect on squander the executives and preservation endeavors. Drawing on existing writing, contextual investigations, and mechanical progressions, the …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 14–22 Read article
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The Emergence of Coxsackievirus A16 Associated with HFMD Colloquially Termed ‘Tomato Flu’ in India 2022: A Detailed Virological Inspection
Abstract: As the world battles the COVID-19 pandemic and grapples with a concerning spike in monkeypox cases, India has encountered another viral illness dubbed "Tomato Flu." Tomato Flu is a viral disease caused by coxsackievirus A16, which is a highly infectious illness affecting children under 10 years old.. Enterovirus A71, CV-A16, CVA6, and echoviruses are the causes of what is also referred to as hand, foot, and mouth disease (HFMD). The …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 29–40 Read article
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Physicochemical Analysis of Groundwater Quality In Owerri Municipal, Imo State, Nigeria Using MATLAB and ANN Models.
Abstract: The physicochemical analysis of groundwater quality in Owerri Municipal council, Imo state, Nigeria was carried out. Fifteen water samples were randomly selected from the five villages that make up Owerri municipal council were anlayzed for physicochemical parameters using standard methods. The results from the study area showed that the temperature ranged between 26.5-28.0oC; рH ranged between 4.80-5.32. Electrical conductivity ranged between 77-166 µЅ/cm. The total dissolved solids were between 35.4-168.4mg/l; …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 Read article
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Stabilization of Heavy Metal Sludge to Pass the TCLP Test Using Cement with a Sinter as a Additive
Abstract: According to the U.S. Stabilisation is the best-proven technology now in use, according to the Environmental Protection Agency's definition in Title 40, Part 268 of the Code of Federal Regulations (40 CFR 268).This method prevents harmful contaminants from leaking into the environment by physically and chemically trapping them all in a matrix. The investigations used 15 different water-mixed combinations of cement, fly ash, sinter, and lime. The study also examined …
Published in Journal of Polymer & Composites · Vol. 11, Issue 10, 2023 · pp. 16–24 Read article
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Striking the Balance: Exploring the Interplay Between Quality and Cost in Modern Production Engineering
Abstract: This review paper examines the intricate and evolving relationship between quality and cost in the context of modern production engineering. In today's dynamic manufacturing landscape, the pursuit of excellence in product quality necessitates a strategic alignment with cost-effective methodologies, ensuring the sustainability and competitiveness of practices. This article serves as a comprehensive synthesis of current research, methodologies, and case studies, aiming to illuminate the dynamic interplay, challenges, and strategies adopted …
Published in International Journal of Industrial and Product Design Engineering · Vol. 1, Issue 2, 2023 · pp. 10–15 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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Mechanical Characteristics of Naturally Woven Coconut Sheath/Short Sisal Fiber Reinforced Polymer Hybrid Composites
Abstract: This study presents the outcomes of an experimental investigation focusing on the tensile, flexural, impact and water absorption properties of unsaturated polyester resin reinforced with naturally woven coconut sheath and short sisal fibers. Sisal fiber, characterized by its abundance, affordability, degradability, and robust strength, serves as a compelling reinforcement. The naturally woven coconut sheath fibers, discreetly found in the hidden sections of coconut branches, offer an inexpensive, biodegradable option with …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 34–44 Read article
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Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
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Application of Medicinal Plants to Cure Mental Disorders
Abstract: Mental fitness is a state of well-being in which individuals apprehend their talents, manage existing pressures, remain efficient, and contribute to their groups. Mental contamination regularly used interchangeably with intellectual illness, is vital to apprehending and addressing man or woman desires and challenges. Schizophrenia, a psychological disorder characterized by hallucinations and delusions, is a complex situation with two important classes: bad symptoms (withdrawal from social interactions, loss of force, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 69–78 Read article
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Enhancing Health, Safety, and Environmental Awareness through Animation: A Multifaceted Approach
Abstract: Animation is a process of visualizing different modes of communication by making an illusion of motion in sequences, which makes an easy medium between the maker and the viewer. Animation design is poised to revolutionize the realms of environment, health, and safety in the future world. This study explores the pivotal role of animation in these domains and its potential impact on shaping a more sustainable and secure future. Concerning …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 58–68 Read article
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Evaluation Of the Quality of Sleep in Healthy Individuals Based on Practice of (CYP)- A Pilot Study.
Abstract: Introduction-Sleep is basic requirement of all living beings. Specially, in human beings it is considered as one of the supportive factor of existence. Ahara(food), Nidra(sleep) and Bramhacharya(righteous conduct/celibacy) are the three factors explained in classical texts as Traya Upastambha(Tripods). Not only Ayurveda literatures, its description and importance is available in Upanishads too. Mandukya Upanishad has allotted a full chapter on sleep and consciousness. But, as the era has entered into …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 40–47 Read article
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Review of Punravartak Jwara with Relationship to Recent Surge in Cardiac Death and COVID-19 Infection
Abstract: The unprecedented 12.5% surge of sudden cardiac death has been reported after COVID-19 outbreak. Central health agency has opined that the COVID-19 vaccine has no relationship with this surge; but the sudden cardiac death with shift i.e. the sudden cardiac death of young in their 40 even with cases of sudden cardiac death in the age group of 20–40. This paradigm change in the prevalence is of serious concern as …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 27–31 Read article