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412 articles for “Gene targeting”
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Nanotechnology meet phytomedicine towards smarter drug delivery system.
Abstract: Using bioactive substances derived from plants, or phytomedicine, has long shown promise in treating a variety of illnesses with fewer adverse effects than synthetic medications. Nevertheless, a lot of phytochemicals have issues with inadequate targeting in vivo, low bioavailability, poor solubility, and chemical instability. By enabling encapsulation, controlled release, targeted delivery, and stimuli responsive behavior, nanotechnology provides effective tools to get around these restrictions. This review examines the intersection of …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 46–53 Read article
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Coronary Vascular Disease: A General Review with Specific Reference to Etiology
Abstract: Cardiovascular disease (CVD), the foremost cause of mortality worldwide, has surged by 60% globally, reaching 20.5 million deaths in 2021 from 12.1 million in 1990, as per the latest report from the World Health Federation. While this increase is alarming on a global scale, it raises even greater concerns in countries like India where heart ailments are afflicting individuals at a younger age. The escalation of CVD among the younger …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 36–42 Read article
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Molecular Docking Studies of Wildtype P53 with Damnacanthal and Scopoletin- Phytochemicals Derived from Morinda Citrifolia
Abstract: Cancer is a prominent cause of mortality globally, and it has the potential to impact any region of the body. The tumor suppressor protein P53 plays a significant role in inhibiting tumor growth by regulating DNA repair, inducing cell cycle arrest, promoting senescence, and triggering apoptosis when confronted with genotoxic stress. P53 is found mutated in 50% of cancers where it loses its tumor suppressive properties and gains oncogenic properties …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 20–31 Read article
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COVID-19 Resurgence in 2025: India’s Continuing Public Health Challenge
Abstract: The year 2025 has witnessed the resurgence of COVID-19, reigniting concerns at both global and national levels regarding the persistent threat posed by SARS-CoV-2. In early 2025, India witnessed a moderate resurgence of COVID‑19, characterized by the emergence of Omicron sub-variants and a rise in mild-to-moderate infections. As of mid-June, active COVID‑19 cases in India totaled approximately 6,000–7,400, with hotspots in Kerala (~2,100 cases), Delhi (~600), Maharashtra (~500), and several …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 16–23 Read article
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Herbal Treatment of Lipid Dysfunction: A Review of Procedures Correlated to the Use of Classical Remedy for the Treatment of Dysfunction
Abstract: AbstractResolution with review: The developments were made probable by the enhancement in organizational knowledge and augmented aptitude to recognize precise lipid moieties in definite subdomains. Current Discoveries: Lipid dysfunction largely demarcated, mentions to any genetic signaling occasion connecting a lipid envoy that fixes a protein, for example a receptor, kinase, or phosphatase, which in crack arbitrate the possessions of lipids on definite cellular rejoinders. In conclusion, the influence of lipid …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 3, 2022 · pp. 28–32 Read article
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Baseline Study about Basic Facts on HIV/AIDS
Abstract: AIDS education is important, especially for young generation; and school is the most important means of reaching out to them. This also applies to the recovering alcoholics and drug users who had been correlated with lifetime tendency towards high risk sexual behaviors. It is easy to think that AIDS is only meant to be worried by drug users, the LGBT community, or people having a lot of sexual partners. This …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 1, 2020 · pp. 30–41 Read article
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Cathodoluminescence method to scheme optical remains
Abstract: Cathodoluminescence (CL) microscopy replaces light generation by a focused electron-beam so as to visualize optical information at resolution of electron microscope. High-resolution imaging has pursued on strongly cathodoluminescent substrates, such as glass. Method has been applicable for bio- and nano-sciences, said as CL identification of bio-markers within cells as well as ceramic character interpret to describe plasmon components from glass supported devices, given by, sensors, waveguides, plasmonic tweezers, and thin-film …
Published in Journal of Microelectronics and Solid State Devices · Vol. 8, Issue 2, 2021 · pp. 7–14 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Mystic Malignant Melanoma Modalities
Abstract: Melanoma is a highly aggressive form of cancer with four recognized subtypes. In about 90% of cases, melanoma is diagnosed as a primary tumor, without signs of spreading. If caught early, the survival rate is quite high, reaching around 94%. However, for metastatic melanoma, the survival rate drops significantly to about 40%. Diagnosing melanoma can be tricky, as it shares features with benign conditions like seborrheic keratosis, benign moles, blue …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 1–10 Read article
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Pf Phosphatidylserine decarboxylase: Molecular modeling and inhibithors prediction
Abstract: Plasmodium falciparum (P.f) is a protozoan parasite responsible for the most severe and deadly form of malaria. The resistance of Pf to last resort antimalarial drugs has been reported, there is an urgent need to identify new therapeutic candidates for drug development. Advancements in bioinformatics technologies provide potential cost and time-effective solutions for predicting therapeutic candidates. Phosphatidylserine decarboxylase (PSD) is a member of the lyase family (more specifically, the carboxy-lyases), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 2, 2023 · pp. 60–78 Read article
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Vaccine Acceptability among Healthcare Workers and Employees of St. Luke’s Medical Center – Quezon City Philippines: A Descriptive Study
Abstract: There are numerous studies and pieces of literature on the growing acceptance and hesitancy in receiving vaccines despite their crucial role in combating epidemics and pandemics. Healthcare workers are frontline workers in public health emergencies; thus, their acceptance of vaccines is critical to mitigating infectious diseases. Nevertheless, while vaccines were known to protect against the virus, vaccine acceptability remains understudied. This study aimed to evaluate the level of vaccine acceptance …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 Read article
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An Overview of Heavy-ion Collisions
Abstract: AbstractA large number of experiments have been performed to explore the heavy-ion collisions dynamics using accelerator facilities available in India. The experimental results have revealed that in reactions induced by nucleons or light particles at energies of the order of a few tens MeV, the great majority of the processes one observes are of statistical nature though they cannot be interpreted as a consequence of the decay of a fully …
Published in Journal of Nuclear Engineering & Technology · Vol. 9, Issue 2, 2019 · pp. 8–23 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
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Analysis and Treatment of Greywater by Using Natural and Chemical Coagulants
Abstract: This project consists of collecting the data related to greywater treatment and analysis. The quality of greywater generated in different, especially, developing countries, constituents found in greywater, some treatment systems and natural materials for treatment, some reuse strategies and public perception regarding greywater reuse. The review shows that generation rates are mostly influenced by lifestyle, types of fixtures used and climatic conditions. Contaminants found in greywater are largely associated with …
Published in Journal of Water Pollution & Purification Research · Vol. 7, Issue 3, 2020 · pp. 1–5 Read article
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A Critique of Advanced Instrumentation for Supervising and Regulating Renewable Energy Systems
Abstract: The integration of renewable strength property into the power grid necessitates modern-day tracking and manipulate systems to ensure highest best average overall performance, reliability, and performance. This paper offers a comprehensive analysis of advanced instrumentation applied for monitoring and controlling renewable strength systems. Beginning with an outline of renewable energy assets and their importance in addressing environmental worries and electricity sustainability, the compare delves into the challenges inherent in monitoring …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 1–12 Read article
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The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
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Role of Beowulf Clusters in Next-Generation Military Applications: A Comprehensive Study
Abstract: Beowulf clusters, which utilize cost-effective commodity hardware combined with open-source software for parallel computing, have emerged as a viable and efficient solution for high-performance computing needs. This paper explores their growing relevance and practical applications in modern and future military technologies. Contemporary military operations increasingly rely on rapid data processing, real-time intelligence, high-fidelity simulations, and autonomous decision-making systems. Beowulf clusters offer scalable and adaptable computational power that supports these demands …
Published in Journal of Advances in Shell Programming · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Non -Invasive Ways to Detect Cancer
Abstract: Cancer is a diverse group of diseases characterized by uncontrolled cell growth and division, affecting millions worldwide and being a leading cause of death. The disease typically involves genetic alterations that disrupt the normal balance of cell growth, leading to the formation of tumors. Tumors can be benign, posing no threat as they do not spread, or malignant, capable of invading nearby tissues and metastasizing. There are more than 100 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 59–67 Read article
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In Silico Identification of Therapeutic Agents for Dengue Virus by Molecular Docking
Abstract: The dengue virus causes serious health issues and a loss of quality of life. Dengue poses a yearly threat to half of the world’s population. The drugs that are based on allopathy are expensive and also exhibit toxic effects on tissues and biological activities. It is also generally accepted that most pharmacologically active drugs, including those derived from medicinal plants, are isolated from natural sources. The present study is directed …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 01–14 Read article