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331 articles for “Novel approaches”
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A Novel Secure Cloud Storage Solution: Combining AES-OTP, RSA, and Time-Limited Access Control with Adaptive Key Management
Abstract: The reliance of cloud computing on the data processing and storage structure creates serious security risks. Ensuring availability, security, and integrity of data in cloud settings becomes a challenge for both the individual and the enterprise. This paper will, therefore, introduce a novel Hybrid Cryptographic Framework that combines RSA, One-Time Pad (OTP), and AES as a means of enhancing data security in cloud storage. It employs RSA for secure key …
Published in Current Trends in Signal Processing · Vol. 14, Issue 3, 2024 · pp. 11–20 Read article
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Computational Biomodeling: Transforming Drug Design with Advanced Simulations
Abstract: Computational biomodeling has emerged as a transformative approach in the field of drug discovery, significantly enhancing the efficiency and precision of identifying and optimizing potential drug candidates. This article explores the various computational techniques utilized in drug design, including molecular docking, molecular dynamics (MD) simulations, free energy calculations, and virtual screening, and examines how these methods collectively contribute to the drug development process. The integration of these advanced simulations allows …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 24–29 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Gesture Vocalizer Using Arduino
Abstract: Science and technology have been an indispensable part of our lives, driving innovation and transforming the way we communicate. Communication barriers between the hearing-impaired and the hearing population pose significant challenges in daily interactions. Sign language, a primary mode of communication for the deaf and mute communities, is not universally understood by the general public. This research work presents a novel system for real-time sign language to speech conversion, aiming …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 3, 2025 · pp. 14–25 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Advancements in O-Glycosylation Techniques with Diverse Donor Molecules
Abstract: Since the early stages of carbohydrate chemistry, numerous researchers have employed alkynyl glycosyl donors as key reagents in glycosylation reactions. These donors have played a crucial role in facilitating the synthesis of glycosidic bonds, an essential aspect of carbohydrate-based compounds. Over time, various modifications and improvements have been introduced by different research groups to enhance the efficiency, selectivity, and sustainability of glycosylation processes. A major focus has been on designing …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 7–28 Read article
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AI-based Drug Discovery-Revolutionizing Pharmaceutical Research
Abstract: The traditional drug discovery process is often costly, time-consuming, and prone to high failure rates. The advent of Artificial Intelligence (AI) has revolutionized this field by significantly enhancing efficiency, reducing costs, and improving success rates. AI-driven approaches, including machine learning (ML), deep learning (DL), and natural language processing (NLP), have transformed key areas such as drug target identification, molecular screening, lead optimization, and clinical trial design. AI models can analyze …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 30–44 Read article
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Horizons in Neuralgia Care: Addressing Unmet Needs and Future Prospects
Abstract: Neuralgia refers to intense, sharp, and often chronic pain resulting from damage or irritation to nerves. It is typically characterized by sudden, shooting pain along the course of a nerve, significantly impairing daily functioning and impacting both physical and emotional well-being. Given its intensity and chronic nature, neuralgia presents a complex challenge in clinical management, emphasizing the importance of timely diagnosis and effective intervention to improve patient outcomes. This comprehensive …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
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Generative Design of Bioactive Orthopedic Composites for Fracture Repair Using an Integrated Conditional GAN–Transformer Framework: A Multi-Objective Approach
Abstract: Orthopedic composite implants for fracture repair must simultaneously satisfy conflicting mechanical and biological demands: high fracture toughness, sufficient compressive stiffness, and bioactive surface chemistry enabling osteoblast adhesion and mineralization. Existing design approaches rely on trial-and-error experimentation, yielding sub-optimal trade-offs between these objectives. This paper presents an integrated conditional Generative Adversarial Network–Transformer (cGAN-T) framework for fully computational, multi-objective generative design of hydroxyapatite (HA)-reinforced polymer composite microstructures targeting Orthopedic fracture repair. A …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 21–35 Read article
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Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever
Abstract: The fastest-spreading viral disease in the world is dengue contamination, which is spread by mosquitoes. Carica papaya leaf juice aids in raising the platelet count, and it occurs primarily in tropical and subtropical countries. The primary goal of this study is to inform medical experts about the use of Carica papaya leaf extract formulations (SYRUP) to treat dengue fever, a potentially fatal illness. Approach: To cure this illness, a water …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 23–33 Read article
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Algebraic Foundations of Generalized Signal Processing: A Unified Approach Across Domains
Abstract: Using the techniques of algebra, notably polynomial algebras and modules, algebraic signal processing (ASP) is a contemporary, abstract framework that generalizes conventional signal processing— including Fourier analysis, filtering, and convolution. The notion is to use algebraic structures to explain signals, systems, and transformations such that ideas may be understood and generalized across many domains, including time, space, graph, or group. A unifying theoretical framework called ASP generalizes classical signal processing …
Published in Current Trends in Signal Processing · Vol. 15, Issue 3, 2025 · pp. 33–44 Read article
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Urban Planning and Design Approaches for Redevelopment: Case of Indian Railway Stations Redevelopment
Abstract: Urban society’s spatial and functional needs are reflected in the theories that revolve around planning and design. These theories evolve and shape urban policies that are the frameworks for the future. The practice of these theories differs across the world because of the unique history and geography of urban areas. However, theories encompass a wide range of subjects that occur repeatedly. It is important to understand and contextualise the theoretical …
Published in International Journal of Urban Design and Development · Vol. 4, Issue 2, 2026 · pp. 25–35 Read article
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Efficient Gabor Filter Design Using Verilog HDL with Multiplier-accumulator (MAC) Implementation
Abstract: This paper introduces a novel and enhanced Gabor filter design aimed at addressing the demands of image processing applications using the Verilog Hardware Description Language (HDL). Specifically, it leverages the Reconstruct Gabor filter technique to elevate the performance and quality of standard image outputs. The primary objective of this research endeavor is to simplify the study, conduct an in-depth analysis, and substantially enhance the design's efficiency, all while ensuring the …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 2, 2023 · pp. 40–46 Read article
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A New Computational Method for Dust and Gas Dynamics in Protoplanetary Discs
Abstract: The simultaneous evolution of dust and gas in protoplanetary discs regulates essential events in planet formation, such as dust accumulation, migration, and the initiation of gravitational instabilities. Nevertheless, precisely modelling this interaction continues to provide a significant computing problem owing to the extensive variety of spatial and temporal scales involved. In this study, we introduce an innovative computational framework for simulating dust-gas dynamics in protoplanetary discs, integrating a two-fluid hydrodynamical …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 35–46 Read article
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Depiction-inspired Recipe Generator Using Deep Learning
Abstract: Machine learning has become a crucial part of modern life, influencing various domains. Its applications range from enhancing data-driven business decisions to enabling autonomous vehicles. Advances in machine learning have brought about notable changes in how we interact with technology. In the culinary world, the idea of creating food recipes from images has gained increasing interest. This entails the development of innovative systems that seamlessly convert visual input, such as …
Published in Journal of Open Source Developments · Vol. 11, Issue 2, 2024 · pp. 47–55 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Crystal Engineering Strategies for Tailoring Mechanical Properties of Structural Materials
Abstract: Crystal engineering has emerged as a promising approach for designing materials with tailored mechanical properties, enabling advancements in various fields such as aerospace, automotive, and construction. This review examines the diverse strategies employed in crystal engineering to manipulate the mechanical behavior of structural materials. One key strategy involves controlling the crystal structure at the atomic level through techniques such as alloying, doping, and phase transformations. Alloying introduces foreign atoms into …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 01–06 Read article
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Generative AI-Based Inverse Design of Sustainable Biodegradable Polymers with Target Mechanical and Thermal Properties
Abstract: The escalating global plastic pollution crisis has intensified the urgent need for sustainable biodegradable polymer alternatives that can match or exceed the performance of conventional petroleum-based plastics while minimizing environmental impact. However, traditional polymer discovery approaches are severely constrained by high experimental costs, protracted development cycles spanning years, and fundamental inability to simultaneously optimize multiple conflicting material properties such as mechanical strength, thermal stability, and degradation kinetics. This study presents …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article