Search
288 articles for “Genetic”
-
A Review of Literature on Breast Cancer: Molecular Insights, Clinical Approaches, and Future Perspectives
Abstract: Breast cancer is the leading cause of morbidity and mortality in women globally. Although both men and women can get the condition, women are more likely to get it, and its prevalence has been rising globally in recent years. The epidemiology, risk factors, pathophysiology, diagnosis, treatment options, and survival rates of breast cancer are all examined in this review of recent research. Breast cancer can show up as a lump …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 15–20 Read article
-
A Review on Microbial Enzymes in the Food Industry: Current Innovations and Future Prospects
Abstract: Over the past few decades, microbial enzymes have become indispensable biocatalysts in food production, fundamentally revolutionizing how we approach manufacturing processes while simultaneously enhancing the quality of what we produce. Today, approximately 200 of the 4,000 known enzymes are deployed commercially with proteases, amylases, lipases, and lactases leading the charge in industrial food applications. This review brings together the latest innovations in how we use microbial enzymes for food processing, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 43–53 Read article
-
The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
-
Adoption Barriers to Advanced Reproductive Technologies in the Subsistence Dairy Farming Systems: Key Constraints and the Way Forward
Abstract: The adoption of advanced reproductive technologies (ARTs) in subsistence dairy farming remains limited despite their potential to enhance genetic improvement, fertility rates, and overall productivity. This study explores the key constraints hindering the integration of ARTs, including artificial insemination, embryo transfer, and ovulation synchronization, within small-scale dairy production systems. Financial constraints, lack of awareness, inadequate veterinary support, and socio-cultural resistance are identified as primary barriers. Limited access to affordable credit, …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article
-
Valorization of Fruit and Vegetable Wastes for CA Production: A Comprehensive Review with Emphasis on Aspergillus niger Bioprocessing and Future Prospects
Abstract: Citric Acid (CA) is a multifunctional organic acid with diverse industrial applications, recently gaining prominence in polymer and composite science as a green crosslinker, compatibilizer, and functional additive. Conventionally produced through submerged fermentation of refined sugars by Aspergillus niger, industrial CA production faces sustainability challenges due to reliance on food-grade substrates. This review highlights emerging strategies for CA biosynthesis from vegetable and fruit processing residues—including cucumber peels, broccoli stalks, spinach …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 807–822 Read article
-
Systematic Review of Application of Nature-Inspired Algorithms for Resource Optimization in Multi-Programmed Operating Systems
Abstract: Multi-programmed operating systems are increasingly confronted with complex challenges in efficiently managing system resources, primarily due to the need to handle numerous concurrent processes with diverse and often conflicting resource demands. As these systems evolve, ensuring optimal performance across various dimensions, such as CPU scheduling, memory allocation, and load balancing, has become crucial. In this context, nature-inspired algorithms have emerged as promising solutions for enhancing resource optimization. These algorithms, which …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 2, 2025 · pp. 08–14 Read article
-
A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article
-
Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
-
Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
-
Comprehensive Study and Triggering Factors of Alcoholic and Non-Alcoholic Fatty Liver
Abstract: Over the past few years, fatty liver disease has turned out to be a rather widespread phenomenon and has become a serious issue with the global population nowadays. It comprises alcoholic fatty liver disease and non-alcoholic fatty liver disease, which develop under the influence of various initiating factors, though frequently follow similar pathologies. The overloading of lipids in the hepatocytes in most cases will be the first sign of the …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 43–52 Read article
-
How Scientists Look for New Pathogens Before They Spread
Abstract: Emerging infectious illnesses are a persistent danger to global health. They often come from unexpected places, such wildlife reservoirs, changes in the climate, or human activities. Finding new diseases before they create epidemics is one of the biggest problems in modern epidemiology. This article talks about how scientists use genetic monitoring, field sampling, and real-time data processing to find, track, and describe new infectious organisms in a way that works …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 11–17 Read article
-
Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
-
Integrative Perspectives on Lipoma: Traditional Therapeutics from Siddha, Ayurveda, and Unani with Biomedical Correlates
Abstract: Background: Lipoma is the most common benign soft tissue tumor, with an incidence of approximately 2 per 1,000 individuals annually. Modern biomedicine attributes its pathogenesis to genetic abnormalities like HMGA2 rearrangements and dysregulated adipogenesis via PPARγ pathways. Effective pharmacological therapies are lacking. Traditional Indian systems – Siddha, Ayurveda, and Unani – offer unique perspectives and non‑surgical approaches yet remain underexplored in integrative research. Objective: To critically evaluate the descriptions, pathophysiological …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 19–33 Read article
-
Transforming Rare Disease Diagnosis with AI
Abstract: Artificial intelligence is changing healthcare fast. It is making diagnoses accurate, helping doctors get better results, and streamlining how care works. This paper looks at how AI shows up in healthcare right now – where it is already making a difference, what is working, and what is still tricky. The focus is on machine learning, natural language processing, and computer vision. Particular attention is given to using AI in diagnosing …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
-
AI-Assisted Optimization of Supersonic Airfoil Shapes Using CFD Coupling
Abstract: This paper presents a novel framework for optimizing supersonic airfoil geometries through integrated artificial intelligence and computational fluid dynamics coupling. Traditional gradient-based optimization methods for high-speed aerodynamic shapes suffer from computational expense and convergence difficulties in non-convex design spaces. The proposed methodology employs a deep neural network surrogate model trained on high-fidelity Reynolds-Averaged Navier-Stokes solutions to approximate aerodynamic performance metrics across the design space. A hybrid particle swarm-genetic algorithm searches …
Published in Journal of Aerospace Engineering & Technology · Vol. 16, Issue 1, 2026 Read article
-
Redefining Herd Health: No-Antibiotic Strategies for Revolutionizing Sustainable Dairy Development
Abstract: This study investigates the potential of no-antibiotic strategies to transform herd health management andpromote sustainable dairy development. Rising concerns over antimicrobial resistance (AMR) and the environmental consequences of antibiotic use have intensified the demand for alternative, sustainable disease management approaches. No-antibiotic strategies emphasize preventive health measures, biosecurity, and holistic practices, including optimized nutrition, vaccination, and natural antimicrobial alternatives. The study evaluates diverse management interventions, such as precision livestock farming, genetic …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
-
A Comprehensive Review on Premature Hair Graying: Factor Contributing, Pathogenesis, Prevention Strategies, and Natural Therapeutic
Abstract: Premature graying of hair (PGH), also known as early canities, is an increasingly common dermatological concern characterized by the loss of natural hair pigmentation before the expected age. Hair color is primarily determined by the quantity and type of melanin synthesized by melanocytes within the hair follicle. Disruption in melanocyte function, survival, or melanin synthesis leads to hair graying. Multiple intrinsic and extrinsic factors contribute to PGH, including genetic predisposition, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 · pp. 13–20 Read article
-
Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
-
Supply Chain Design Considering Social and Environmental Risks
Abstract: The aim of the research is to design a supply chain taking into account social and environmental risks. In this research, an attempt was made to present a model that, by considering variables close to the real world, simultaneously considers cost and sustainability issues for designing a meat supply chain network, including locating facilities, using technology in them, how products flow in the network, etc. In order to examine the …
Published in International Journal of Industrial and Product Design Engineering · Vol. 4, Issue 1, 2026 · pp. 35–43 Read article
-
AI-Accelerated Development of Gradient Polymer Nanocomposite Thin Films
Abstract: Gradient polymer nanocomposite thin films are an active field of materials research due to the fact that it enables scientists to de-facto regulate the optical, electrical, and mechanical properties of a film by merely altering its composition on a layer-by-layer basis. This type of control opens the gate to the improved flexible electronics, long lasting protective coats, and the new smart gadgets. The problem is, though, that it is a …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 456–469 Read article