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332 articles for “Gene medicine”
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Advanced Controlled Drug Delivery Systems
Abstract: Polymer-gel forms have gained popularity in medicine as means of medication delivery over the skin. This is so since they enable medications pass the skin more readily. These products allow medicine to be administered without surgery and provide continuous active ingredient supply. They are excellent for long-term therapy for managing conditions that keep resurfacing. From tiny synthetic ones to huge biological ones, polymer gels can store a wide spectrum of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 271–284 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Advanced Miasmatic Approach in Ante Natal Care - Multi Faceted Homoepathy
Abstract: Homeopathy and pregnancy care? Looks challenging? The structural deformities investigation in modern medicine is an unforeseen combination of a physical, mental breakdown of pregnant lady, resulting an immediate call for effective therapy of the lady and family. The female-being the pivot, her health in pregnancy marks great responsibility for an Altruistic homeopath. The advanced miasmatic lens in antenatal care magnifies the role of multifaceted homeopathy. Such type of synergistic efforts …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 29–37 Read article
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Commonest Mode of Suicide in Jorhat District—One Year Retrospective Study
Abstract: One who succeeds in completing the act of suicide, has nothing to bother about and it is only the survivors who are the bear the consequence. Society must identify the potential cases of suicide prone and help and treat them in time irrespective of the method they apply to commit it. The modes of suicidal deaths in an area reflect the socio-economic status and mental health status of the population …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 2, 2017 · pp. 1–4 Read article
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Confident but Wrong: A Lifecycle Analysis of Hallucination in Large Language Models Understanding AI's Confidence Problem
Abstract: A Large Language Model (LLM) is likely to produce sentences that are fluent and confident in many instances, but completely wrong. In many cases a Large Language Model (LLM) will produce a fluent and confident sentence that is completely incorrect. This review tries to analyze this phenomenon using the most recent literature regarding natural language generation, computational learning theory and benchmark experiments. The argument is that it is not a …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 3, 2025 Read article
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Presentation Delay in Breast Cancer Patients, Identifying the Barriers Among Women Receiving Breast Cancer Drugs at Hawassa University Comprehensive and Specialized Hospital, Ethiopia
Abstract: Background: Breast cancer remains the most common cancer and most common cause of cancer-related mortality among women worldwide [1]. While incidence rates have historically been higher in the developed world, there has been a recent sharp increase in incidence and mortality in the developing world [2]. Objectives: The main purpose of this study was to assess the barriers resulting in delayed patient presentation to breast cancer care among women receiving …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 24–31 Read article
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Management of Chronic Hepatitis and Copper Accumulation with Ayurveda – A Single Case Study
Abstract: Hepatitis is a general term can be define as inflammation of the liver caused due to several factors such as viruses, chemicals, drugs, alcoholand certain genetic disorders or by an overactive immune system which mistakenly attacks the liver known as autoimmune hepatitis. Hepatitis can be acute, which appears immediately and goes away quickly, or chronic, which is a long-term condition that typically produces more mild symptoms and gradually damages the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2023 · pp. 14–18 Read article
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Photoreceptor Dynamics: Light Sensing and Cellular Responses for Photochemistry
Abstract: Photoreceptor dynamics represent a fundamental aspect of photochemistry, encompassing the mechanisms by which biological systems detect and respond to light stimuli. Photoreceptors are specialized proteins that undergo structural and functional changes upon photon absorption, initiating a cascade of molecular events that translate light signals into cellular responses. These proteins are ubiquitous across life forms, including microbial rhodopsins, plant phytochromes, and animal opsins, each finely tuned to specific wavelengths and light …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 28–32 Read article
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The Invisible Engineers: How Viruses Change Cells at the Molecular Level
Abstract: Viruses are frequently thought of as simple parasites, yet at the molecular level, they are quite good at engineering and may change the way the cells they infect work. The Invisible Engineers: How Viruses Rewire Cells at the Molecular Scale looks into how viruses get into host cells, mess up intracellular circuits, and exploit molecular resources to make copies of themselves. This article talks about how viral proteins and nucleic …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 1–6 Read article
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Bacteriophages- A New Frontier in Medicine
Abstract: Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering an innovative alternative to traditional antibiotic treatments, especially in the face of rising antibiotic resistance. The resurgence of phage therapy has been driven by the increasing prevalence of multidrug-resistant bacterial strains and the slowdown in the development of new antibiotics. Phages, unlike antibiotics, target specific bacterial strains, reducing the impact on the natural microbiota and potentially offering a …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 31–35 Read article
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The Principles and Applications of Structural Symmetry in Natural and Engineered Systems: A Comprehensive Review
Abstract: Structural symmetry is a fundamental constraint across scientific domains, dictating the stability, functionality, and efficiency of systems from the subatomic to the macroscopic. In physics and chemistry, symmetry is mathematically defined through Group Theory, specifically point groups (e.g., Cnv, Oh). These groups govern molecular orbital interactions; high-symmetry configurations, such as the icosahedral C60 fullerene, achieve optimal energy distribution and structural resilience. In Structural Biology, symmetry is an evolutionary strategy for …
Published in Emerging Trends in Symmetry · Vol. 2, Issue 1, 2026 · pp. 30–34 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Design and Implementation of Low Latency 16-bit Full Adder
Abstract: In the new age world, modern technology has vast applications in various fields of engineering, medicine, and others. Digital electronics processing and systems play a vital role in the analysis and computation of data representation. Electronic systems have gradually become faster and smaller scale. The primary structural element of any modern ALU-based processor is an adder. Addition is a well-known extremely basic function that is employed in nearly all computing …
Published in Journal of VLSI Design Tools and Technology · Vol. 14, Issue 3, 2024 · pp. 21–31 Read article
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Lifestyle Factors and Perceptions of Diabetes Among Individuals in North India
Abstract: Background: Diabetes mellitus is influenced by a complex interplay of genetic, environmental, and lifestyle factors. In North India, unique socio-cultural and dietary patterns shape individual behaviors and perceptions toward diabetes. Understanding these lifestyle choices and cultural beliefs is critical for designing interventions that improve adherence to medical treatment and promote healthier outcomes.Methods: A cross-sectional survey was conducted among 1,500 individuals diagnosed with diabetes across selected urban and rural districts in …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Complementary and Alternative Therapies for High Blood Pressure: An Evidence Based Approach
Abstract: High blood pressure is a disorder of circulatory system characterized by the sustained, non-physiologic rise of systemic blood pressure. It is considered as the leading cause of death in the world. In India and its encompassing nations, the awareness level for hypertension is <45%. Only 50% of these are on treatment and adequacy of control of blood pressure is exceptionally poor. Standard medical practices being employed currently for treating high …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 1, 2019 · pp. 38–44 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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Lab Reagents and Their Importance in Bio-chemistry
Abstract: Biochemical reagents are essential substances in the study of life at the molecular level. These reagents help scientists detect, identify, and quantify bio-molecules such as proteins, carbohydrates, nucleic acids, and enzymes in biological systems. They play a vital role in understanding metabolic reactions and physiological processes within living organisms. Biochemical reagents are generally classified into analytical, diagnostic, enzymatic, chromogenic, and buffer reagents, each serving a specific purpose in laboratory and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 1–4 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article