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1969 articles for “rokitansky’s disease.”
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Assessment and Associated Factors of Adjustment Disorder with Mixed Depression and Anxiety of Hospitalized Patients with Pandemic Disease, COVID-19 in Ethiopia, East Africa, 2020
Abstract: AbstractBackground: Globally, the 2019 coronavirus disease (COVID-19) pandemic has raised international concern. According to world meters report, 4,545,167 cases, 1,715862 recoveries, 303,847 deaths and spread to 213 countries, and significant number increasing from day to day since December 2019. Mental health is becoming an issue that cannot be ignored in our fight against it. This study aimed to explore the prevalence, and factors linked to anxiety and depression in hospitalized …
Published in Research and Reviews: A Journal of Health Professions · Vol. 10, Issue 2, 2020 · pp. 57–65 Read article
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Epigenetic Regulation and Plasticity in Human Diseases
Abstract: In normal human development as well as in the case of diseased development, epigenetic changes are involved. The role of plasticity is important and directed on the understanding feature of epithelial cell biology, and maybe a significant pathway for disease pathobiology and pathogenesis. During embryonic development, an epigenetic mechanism is important for the growth and development of genetically identical cells that are obtained from different outcomes. In this review study, …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 12–20 Read article
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Development of Zinc Gluconate Vitamin C Effervescent Tablet for Immunity Improvement and Management of Corona Virus Disease (COVID-19)
Abstract: The global pandemic of coronavirus disease- 2019 (COVID-19) continues to pose a threat to people, societies, and economic and healthcare systems. COVID-19s progression and lethality are determine by the host immune system, as is the case with many other diseases. revolutionary idea that has been used to treat other diseases is the control of inflammatory response and cytokine production based on immunonutrition. Some COVID-19 clinical trials are now using zinc, …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 2, 2022 · pp. 4–11 Read article
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High Doses Biotin beyond Its Nutraceutical Prescription: Update Indications for Neurological Diseases
Abstract: Biotin or vitamin H is ubiquitous B-complex vitamin that plays as a co-factor in different metabolic process in the body. The usual recommended daily requirement is 30µg. Recent studies found biotin in high doses involved in the synthesis of myelin in patients with multiple sclerosis. The Med Day Pharmaceuticals launched an oral formulation of biotin high dose (Cerenday 100 mg capsule) and recommended for multiple sclerosis. Previous studies demonstrated the …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 2, 2017 · pp. 13–20 Read article
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Chronic Kidney Disease: An Overview
Abstract: The key purpose of this review article is to throw light on chronic kidney disease (CKD). Each day people are diagonised with CKD making the need of proper awareness regarding CKD, one of the top public health priorities. Taking this into consideration, the review article outlines some new insight on identification of CKD, classifying it into several stages based on glomerular filtration rate (GFR)/chronic renal failure (CRF) value to be …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 6–9 Read article
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Gastroesophageal Reflux Disease and the Role of Prokinetics Along with PPIS
Abstract: Gastroesophageal reflux disease (GERD) is often confused with functional dyspepsia as dyspepsia symptom commonly coexist with heartburn and some patients with functional dyspepsia respond to proton pump inhibitor (PPI) therapy. Up to 25–50% of patients with functional dyspepsia defined according to Rome III criteria can have abnormal esophageal acid exposure. Functional dyspepsia presents of one or more of the following symptoms: Postprandial fullness, early satiation, epigastric pain or burning, and …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 2, 2016 · pp. 12–14 Read article
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A Case Report on Alport Syndrome which ends up with Allograft Rejection due to Anti-GBM Disease
Abstract: Alport syndrome (AS) is a condition which is genetically inherited and is characterized by abnormalities in the basement membrane of the kidney, ear and eye as well. It is one of the spectra of diseases representing hereditary nephritis, which inevitably leads to end-stage renal disease (ESRD). Sensorineural hearing loss (SNHL) is also a characteristic feature in AS. The hearing abnormality begins during late childhood or early adolescence and 90% of …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 3, 2019 · pp. 1–4 Read article
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Comparison of Efficacy and Outcome of Radiocephalic and Brachiocephalic Arteriovenous Fistula in Patients of Chronic Kidney Disease
Abstract: Introduction: Hemodialysis is the most common treatment modality for patients with End-Stage Renal Disease (ESRD). Vascular access can be created in the form of arteriovenous fistula (AVF), arteriovenous graft (AVG) or central venous catheter (CVC). Material and Methods: The study was conducted in the Department of Urology, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India from November 2016 onwards on patients who were admitted …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 1, 2019 · pp. 6–12 Read article
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Kapikacchu (Mucuna pruriens): A Promising Indigenous Herbal Drug and Its Effect on Different Disease Conditions
Abstract: Mucuna pruriens is widely known as “velvet bean,” which originally belongs to eastern part of India and China where it is cultivated as vegetable crop. It has been shown that its seeds are potentially of substantial medicinal importance. Kapikacchu belongs to Fabaceae family and it is widely used for aphrodisiac purpose as well as for Parkinson disease. It has lots of pharmacological properties such as hypoglycemic activity, antioxidant activity, aphrodisiac …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 3, 2017 · pp. 1–5 Read article
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Health Status of Children Under Five Years of Age in Context to Personal Hygiene, Immunization Status, And Vitamin Deficiency Diseases: A Review
Abstract: In 2013, an estimated 6.3 million live born children worldwide died before the age of 5 years. In 2015, the under-five mortality rate in low-income countries was 76 deaths per 1000 live births. The importance of under nutrition as an underlying cause of child deaths associated with infectious diseases, and the effects of multiple concurrent illnesses have been emphasized in many studies across the world particularly in the developing countries. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 4, Issue 3, 2017 · pp. 19–22 Read article
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Role of Hijama (Cupping) in the Management of Various Diseases and Probable Mechanism of Action
Abstract: Hijama is derived from Arabic word ‘Hajm’ which literally means to suck. It involves the use of cup like vessels placed on the body surface by creating a vacuum to either let out blood from below the skin surface or just plain suction without bloodletting. Hijama evacuates blood from small vessels spread over the skin and muscles and relieves congestion from the body. It is a therapy with low cost …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 2, 2018 · pp. 19–23 Read article
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Modeling the Novel Coronavirus Disease (COVID-19) as Hidden Markov Chains
Abstract: The Hidden Markov Model has over the years been an appropriate method for modeling diseases such as HIV AIDS, heart failure, and so on. With the ongoing pandemic affecting Nigeria by being responsible for 2,745 death cases out of 207,616 confirmed cases as of October 10, 2021, the need to study an important parameter of COVID-19, the case fatality rate by building a model and estimating the case fatality rate …
Published in Research & Reviews : Journal of Statistics Read article
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Basic Concept and Role of Memory Enhancer (Muqawwi- E-Hafiza) Unani Drugs in the Management of Alzheimer’s Disease (Nisyaan-E-Shekhukhi): A Review
Abstract: Alzheimer's disease is a neurological disorder in which the death of brain cells causes memory loss and cognitive decline, defined as a dementing illness in which anterograde amnesia is a dominant symptom and is the most common cause of Dementia in the elderly. There is no direct mention of this condition in classical Greek literature, but Alzheimer's disease is almost always associated with forgetfulness or fasaad-e-takhayy’ul. Although the etiology is …
Published in Research & Reviews : Journal of Herbal Science Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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The Current State of Huntington's Disease Treatment: An Overview of Palliative Care and Symptom Management
Abstract: Huntington's disease (HD) is a neurodegenerative ailment that adversely affects the basal ganglia and the cortex of the brain. Although there is no recognized cure for HD, symptomatic relief and therapeutic management of the condition have improved over the course of time. This review paper provides an up-to-date overview of the current treatment options and symptom management strategies utilized in the care of HD patients. Additionally, it highlights the existing …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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Unraveling the Nexus: Parkinson's Disease, Alpha-synuclein, Desulfovibrio, and the Gut Microbiome
Abstract: Parkinson's disease (PD) is now recognized as a chronic condition which is once considered a highly intricate disorder involving the central, autonomic, and enteric nervous systems. The prevailing perspective attributes the disease by the formation of Lewy bodies, primarily triggered by the misfolding of α-Synuclein, leading to the demise of dopaminergic neurons in the substantia nigra. Constipation, one of the most common non-motor symptoms in PD patients, is believed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 18–28 Read article
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A Narrative Review on Tuberculosis Disease Transmission, Treatment, Prevention, Emergency Care, and Vaccine Allocation in Second Highest Populated Country (India)
Abstract: Tuberculosis, an airborne illness caused by Mycobacterium tuberculosis, is a highly contagious disease primarily impacting the lungs, though it can also affect other body parts, excluding hair and nails. There are two main types of tuberculosis: pulmonary tuberculosis (PTB), which targets the lungs, and extrapulmonary tuberculosis (EPTB), which involves other areas such as lymph nodes, bones, joints, and the nervous system. The theme for World Tuberculosis Day in 2024 is …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 7–13 Read article