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260 articles for “delivery of drugs”
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Emerging Engineered Nanoweapons for Tumors
Abstract: Cancer is a type of disease characterized by abnormal growth of cells which tend to proliferate in uncontrolled manner. It occurs at molecular level when genes undergo genetic alterations. The malignant growth of tumor cells results in non-functioning of the concerned organ. Over the years, cancer targeting technique has greatly improved by new approaches based on nanotechnology. Nanotechnology is helpful in development of new therapies against cancer. Nanotechnology is a …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 1–6 Read article
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AI-Optimized Biodegradable Polymer Composites for Medical Applications
Abstract: The value of biodegradable polymer composites in the medical practice has been massive as the composites may be deployed to provide temporary structural support, and they are also safe to degrade within the human body. However, the conventional material design process is trial and error, which is ineffective and inefficient. The article proposes a hybrid model involving experimental characterization, as well as an artificial intelligence (AI)-based model, to optimize biodegradable …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Radiopaque Polymer Composites for Improved Visualization of Interventional Devices
Abstract: Radiopaque polymer composites are increasingly important for improving the visualization of interventional medical devices under X-ray and fluoroscopic imaging while maintaining the flexibility, mechanical performance, and processability required for minimally invasive applications. This narrative review summarizes recent developments in radiopaque polymer composites, with emphasis on radiopaque filler selection, polymer–filler interactions, processing strategies, structure–property relationships, biocompatibility, and device applications. A focused literature search was conducted using PubMed, Scopus, Web of Science, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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A Review on Quantum Dots and Their Bioimaging Applications
Abstract: Quantum dots are nanoscale semiconductor crystals engineered to emit highly intense, photo-stable luminescence with quantum yields reaching 90%. Structurally, they are synthesized as single-substance core types, hetero-structured core-shell architectures for enhanced stability, or blended alloys. They are further categorized by synthesis and functional traits into colloidal, magnetic, and highly fluorescent varieties, alongside specialized silicon and eco-friendly carbon-based variants derived from organic waste. Due to their exceptional optoelectronic properties, they are …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 2, 2026 · pp. 41–60 Read article
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Fabrication and Characterization of Diacerein Loaded Nanosponge for Topical Delivery
Abstract: Diacerein, an anti-inflammatory drug, which comes under BCS class II, commonly used in treatment of osteoarthritis has limited by its poor solubility and bioavailability when administered topically. This study aimed to develop and evaluate diacerein-loaded nanosponges gel using varying concentrations of ethyl cellulose and polyvinyl alcohol (PVA) to enhance its delivery. Nanosponges were prepared using an emulsion solvent evaporation technique, with different ratios of ethyl cellulose (0.05-0.250%) and PVA (0.2-0.3%). …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 26–46 Read article
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Studies on the Self-Assembly of Steroids and DNA Mediated by Naphthalene-Based Amphiphilic Block Copolymer
Abstract: Amphiphilic block copolymers have attracted considerable interest in pharmaceutical and biomedical applications, including controlled drug release, gene delivery, and biomolecular sensing. In this study, fluorescent amphiphilic block copolymers were designed to facilitate interactions with biological molecules, such as DNA and antiviral agents, enabling their behavior to be monitored through fluorescence spectroscopy. Two novel block copolymers, poly(methyl methacrylate)-b-poly(dimethylaminoethyl methacrylate-co-naphthyl methacrylate) [PMMA-b-P(DMAEMA-co-NMA)] and poly(styrene)-b-poly(tert-butyl acrylate-co-naphthyl methacrylate) [PS-b-P(t-BA-co-NMA)], were synthesized successfully via atom …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 183–196 Read article
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Formulation and Evaluation of Luliconazole Loaded Microemulgel
Abstract: The aim of present study is to formulate and evaluate Luliconazole Microemulgel. Microemulgel is combination of microemulsion and gel. The problem associated with delivery of hydrophobic drug can be solved by incorporating drug in microemulsion and then microemulsion is combined with gel to form microemulgel. Solubility of Luliconazole is determined and it was found to be soluble in ethanol, methanol, chloroform, while it was insoluble in water. The melting point …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 3, 2026 Read article
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Blockchain Technology for Strengthening the Indian Generic Medicine Supply Chain and Combating Counterfeit Drugs
Abstract: India is one of the leading distributors of generic medicines globally, but its supply chain faces numerous challenges including substandard medicines, counterfeiting, and inefficient logistics. Blockchain technology offers a promising solution by providing a secure, decentralized, and transparent platform to track and verify the entire drug supply chain from production to delivery. This paper investigates the potential of blockchain to mitigate counterfeit drug circulation, improve trust in Indian generic medicines, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 9–12 Read article
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Space Pharmacy for Human Space Exploration: Overcoming Drug Stability, Packaging Challenges, Pharmacokinetic Variations, and Developing Innovative On-Demand Therapeutic Solutions for Long- Duration Missions Beyond Earth
Abstract: As humankind prepares for prolonged space exploration and the establishment of lunar and Martian habitats, ensuring reliable access to safe and effective medicines has emerged as a critical challenge. The evolving discipline of space pharmacy addresses the unique pharmaceutical needs of astronauts in microgravity and radiation-rich environments, where drug stability, packaging, and pharmacokinetics are markedly different from conditions on Earth. Traditional dosage forms often undergo accelerated degradation, while altered fluid …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 32–47 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 50–64 Read article
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Formulation and development of Lamivudine Nanoemulsion by using Emulsifying Polymers and It’s Evaluation
Abstract: Nanoemulsion is a novel approach to medicine delivery that helps to increase the bioavailability of drugs that aren’t particularly soluble in water. In this research work, nanoemulsion of Lamivudine was formulated by using polymers such as SPAN 80, TWEEN 80 and Whey protein concentrate with the help of Ultrasonication technology. The formulation was optimized. It was evaluated by assessing pH, viscosity, turbidity, in vitro franz diffusion study, particle size distribution, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 22–35 Read article
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Polysaccharide-Based Hydrogels for Sustained Drug Release in Pharmacology
Abstract: Polysaccharide-based hydrogels have showed great potential in medicine as materials for long-lasting, under control medication delivery systems. Natural polysaccharides include chitosan; alginate, agarose, and cellulose form these hydrogels. Among its many advantages are biocompatibility, biodegradability, and customising ability for various drug release rates. Reacting to pH, temperature, and ionic strength changes in the surroundings, polysaccharide-based hydrogels may swell. For usage requiring the release of therapeutic substances over an extended period …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 300–312 Read article
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Drug Marketing in Tropical Regions and Its Effect on Pharmacovigilance Awareness and Reporting
Abstract: Drug marketing practices in tropical regions present a complex interplay between pharmaceutical promotion, healthcare infrastructure limitations, and public health outcomes. These regions – characterized by high disease burden, socio-economic disparities, and diverse healthcare delivery systems – often experience unique challenges in ensuring safe and rational drug use. Aggressive and sometimes unregulated marketing strategies by pharmaceutical companies may significantly influence prescribing behavior, patient compliance, and, ultimately, pharmacovigilance systems. Pharmacovigilance, defined as …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 · pp. 1–17 Read article
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Solid Lipid Nanoparticles in Medicine: Formulation, Characterization and Future prospects
Abstract: An alternative to conventional colloidal carriers such liposomes, polymeric nanoparticles, and emulsions, solid lipid nanoparticles (SLNs) were created in the early 1990s. Benefits include targeted medicine distribution, controlled drug release, and improved stability. An extensive review of the excipients utilized, the production techniques, including the membrane contractor approach, and the possible advantages and disadvantages of SLNs is given in this work. It investigates secondary stabilization techniques like freeze-drying and spray-drying, …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 1–15 Read article
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The Role of Artificial Intelligence and Machine Learning in Redefining Global Healthcare Systems and Advancing Medical Innovation
Abstract: Health Services are being revolutionized with AI and ML through improved accuracy, efficiency and accessibility in the delivery of health care. With AI and ML, it is now possible for health care professionals to assess varying amounts of complex clinical data in a relatively short amount of time, therefore, creating opportunities for early detection of disease, increasing the odds of accurate diagnosis, and improving the ability to make informed clinical …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 14–19 Read article
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Polymer Chemistry in Sustained-Release Herbal Composites: Designing a Stable Euphorbia tithymaloides Topical System with Phospholipid and Polymer Matrices
Abstract: Polymer chemistry enables the stabilization and sustained release of herbal actives, critical for topical therapeutic applications. This study explores a novel process for preparing a stable, sustained-release topical composition of Euphorbia tithymaloides, leveraging polymer-based systems. Ethanolic extract (50 mg) of the plant, rich in unstable sugar moieties (e.g., D-ribose) and sterols (e.g., stigmasterol), is encapsulated within a phospholipid matrix of phosphatidylcholine (50–100 mg) and cholesterol (50–100 mg). This lipid-polymer complex, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 165–171 Read article
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Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance
Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article
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Nanotechnology in Surgical Drains: Reducing Infections and Promoting Healing Post-Surgery
Abstract: Surgical drains are widely used in postoperative care to evacuate accumulated fluids, minimize dead space, and reduce complications such as hematoma and seroma formation. Despite their clinical importance, conventional drains are frequently associated with retrograde bacterial migration, biofilm formation, and increased risk of surgical site infections (SSIs), which contribute significantly to postoperative morbidity and prolonged hospital stay. Recent advancements in nanotechnology have enabled the development of nano-functionalized surgical drains with …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 · pp. 54–67 Read article
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Evaluation of Mucoadhesive Polymers for Nasal Delivery of Herbal Bioactives
Abstract: A study assessed mucoadhesive polymers for intranasal herbal bioactive administration with higher residence time and mucosal permeability. Chitosan, Carbopol® 934P, and HPMC K15M were utilized to manufacture mucoadhesive nasal gels with standardized herbal bioactive fractions. Formulations were examined for pH, viscosity, spreadability, drug content, mucoadhesive strength, in-vitro release, ex-vivo penetration, and short-term stability. All formulations demonstrated a suitable pH for nasal usage and uniform drug content (97.48 ± 1.12% to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1680–1689 Read article