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307 articles for “gene regulation”
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Transforming Road Safety: A GPS Enhanced Car Accident Alert System for Rapid Emergency Response
Abstract: Road accidents continue to be a major global health concern, with consequences for both emergency response times and public safety. The “Transforming Road Safety: A GPS Enhanced Car Accident Alert System for Rapid Emergency Response” that this project suggests would help emergency services respond to car accidents more quickly and efficiently. In this review paper, we investigate a system that uses sensors and GPS to enhance road safety and accident …
Published in Current Trends in Signal Processing · Vol. 14, Issue 2, 2024 · pp. 19–24 Read article
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Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
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A Review on Microbial Enzymes in the Food Industry: Current Innovations and Future Prospects
Abstract: Over the past few decades, microbial enzymes have become indispensable biocatalysts in food production, fundamentally revolutionizing how we approach manufacturing processes while simultaneously enhancing the quality of what we produce. Today, approximately 200 of the 4,000 known enzymes are deployed commercially with proteases, amylases, lipases, and lactases leading the charge in industrial food applications. This review brings together the latest innovations in how we use microbial enzymes for food processing, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 43–53 Read article
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Digital Literacy: A Faculty-Based Comparative Study of Research Scholars at the University of Rajasthan
Abstract: This study explored how much “research scholars in the department of Social Science and Arts of the University of Rajasthan, Jaipur”, understand and use digital technologies. The findings based on 84 questionnaires show that scholars of the Social Science faculty have a relatively high digital literacy compared to those in the Arts faculty. Most of the respondents indicated that they were skilled in using open-access sources. However, about a quarter …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 · pp. 34–43 Read article
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Photovoltaics and Thermal Solar Technologies: Innovations for Sustainable Heating, Cooling, and Energy Efficiency
Abstract: Developments in renewable energy technology, in particular photovoltaics (PV) and solar thermal systems, have been fueled by a rising demand for energy worldwide and the pressing need to slow down climate change. These technologies provide greener options for heating, cooling, and energy production by lowering dependency on fossil fuels and greenhouse gas emissions. This study examines developments in solar thermal and photovoltaic technologies, their uses in commercial, industrial, and residential …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 12, Issue 1, 2025 · pp. 30–37 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
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Water Comparative Study of Water Quality
Abstract: Water quality plays a vital role in safeguarding human health, maintaining environmental balance, and supporting socio-economic progress. For drinking purposes, water must satisfy established physical and chemical criteria to minimize health hazards and ensure the efficient functioning of biological processes. This research focuses on a comparative assessment of drinking water quality by analyzing key parameters such as pH, Total Dissolved Solids (TDS), hardness, and fluoride levels in both tap water …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 85–98 Read article
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Gesture-Based Virtual HCI: Enhancing Computer Interaction
Abstract: In a time when human-computer interaction (HCI) is changing quickly, generating user-friendly interfaces is essential. This paper presents a new technique to HCI using virtual mouse and keyboard systems based on gesture recognition. This system replaces classical input devices by permitting users to control their computers with hand gestures using computer vision techniques. We created an optical mouse and keyboard technique that can recognize hand gestures recorded by a regular …
Published in Journal of Microelectronics and Solid State Devices · Vol. 11, Issue 2, 2024 Read article
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An Overview on Energy Harvesting Using Piezoelectric Material for Wi-Fi Systems
Abstract: The rapid proliferation of wireless-networked devices has intensified the demand for sustainable, maintenance-free power sources that can keep small-scale Wi-Fi modules operational in hard-to-reach or infrastructure-limited environments. This study investigates the feasibility of harvesting ambient mechanical energy using piezoelectric transduction technology and directly feeding the harvested power to a low-power Wi-Fi communication subsystem. A compact energy-harvesting module was engineered from lead-zirconate-titanate (PZT) cantilevers with resonant frequencies tuned to the dominant …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 56–63 Read article
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Diet-Driven Enhancement of Immune Resilience, Disease Resistance, and Performance: Mechanistic Insights, Nutritional Interventions, and Implications for Sustainable Dairy Development
Abstract: This review synthesizes current knowledge on how dietary strategies can strengthen immune resilience, improve disease resistance, and enhance productive performance in dairy systems while advancing sustainable development. Immune function in dairy cattle is profoundly influenced by nutrition, with energy, protein, essential amino acids, fatty acids, vitamins, minerals, and bioactive compounds playing critical roles in shaping both innate and adaptive immune responses. Suboptimal nutrition impairs immune competence, increases susceptibility to infectious …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 15–24 Read article
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Pulmonary Effects of Cement Exposure in Construction Workers Correlating Lung Function Parameters with Workplace Hygiene
Abstract: Construction workers are routinely exposed to cement dust, a recognized occupational hazard known to adversely affect respiratory health. This study investigates the pulmonary effects of cement exposure in construction workers by evaluating lung function parameters and examining the role of workplace hygiene practices. A cross-sectional analysis was conducted on a sample of construction workers with varying durations of exposure to cement dust. Spirometric assessments, including forced vital capacity (FVC), forced …
Published in Journal of Industrial Safety Engineering · Vol. 12, Issue 3, 2025 · pp. 13–19 Read article
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Nutraceutics: Opening the Debate for a Framework for the Safety and Efficacy of Nutraceuticals Formulations
Abstract: As of right now, there is no precise definition for nutraceuticals that distinguishes them from other food-based categories such herbal products, dietary supplements, pre- and probiotics, functional foods, and fortified foods. Several studies have shed light on the possible mechanisms of action of pharmaceutically active ingredients in food, emphasizing their ability to improve health, lower the risk of disease, and promote general wellbeing. However, Nutraceuticals confront difficulties in substantiating safety …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 27–33 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Technical Advances in Drone Applications for Environmental Surveillance
Abstract: Unmanned Aerial Vehicles (UAVs), or drones, have rapidly evolved into essential tools for environmental monitoring and conservation due to their advanced sensor integration, real-time data acquisition, and autonomous operational capabilities. This review explores the multidisciplinary convergence of drone technologies with environmental science, emphasizing the technical and engineering aspects that drive these applications. The study outlines key UAV system components—including multispectral and hyperspectral imaging, LiDAR, thermal sensing, and real-time GPS-AI integration—highlighting …
Published in International Journal on Drones · Vol. 1, Issue 2, 2025 · pp. 14–20 Read article
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Antimicrobial Resistance and AI-Based Strategies for Rapid Pathogen Detection
Abstract: Antimicrobial resistance (AMR) has become a major global health threat, significantly reducing the effectiveness of antimicrobial therapies and increasing the burden of infectious diseases worldwide. The rapid emergence of multidrug-resistant pathogens has created an urgent need for faster, more accurate, and scalable diagnostic approaches to support timely treatment and effective infection control. Artificial intelligence (AI) has emerged as a promising technology capable of transforming pathogen detection and AMR surveillance through …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Comparative Analysis of Dip and Spray Techniques with Ethanol, Polyvinyl Alcohol, and Acetone Hydrophobic Glass Slides with Al2O3 Coating
Abstract: The hydrophobic effects of Al₂O₃ coatings on glass slides are investigated in this work by comparing dip and spray procedures using three distinct solvents: acetone, polyvinyl alcohol (PVA), and ethanol. Using both dip and spray techniques, the experimental design systematically applies Al₂O₃ coatings on glass slides. Then, the effect of the chosen solvents on hydrophobicity is investigated. Delineating the complex interaction between coating processes and solvent options requires careful analysis …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 45–51 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Invisible Shield: How the Atmosphere Keeps Us Safe from Space
Abstract: Invisible Shield shows us how incredible Earth's atmosphere is at keeping us safe from space threats. The atmosphere is a moving, multi-layered shield that keeps us safe from harmful solar radiation and burns up meteoroids before they impact the ground. This page discusses about the science behind climate control, magnetic interactions, and atmospheric chemistry. It depicts how various systems work together to keep the ground stable. It also talks about …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 39–49 Read article