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477 articles for “Pathways”
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Effectiveness of PTFE-Based Nano-coatings in Improving Corrosion and Wear Resistance of Stainless Steel
Abstract: Polytetrafluoroethylene (PTFE) has emerged as a highly effective material for enhancing the durability and performance of metal surfaces, particularly in environments requiring superior corrosion resistance and low friction. This study investigates the application of PTFE coatings on various metallic substrates, with a focus on stainless steel and carbon steel, to improve their corrosion resistance, wear protection, and tribological performance. Utilizing advanced deposition techniques such as sol-gel and plasma spray, PTFE …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 2, 2024 · pp. 32–38 Read article
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Exploring the Dynamics of Eye Fluid: Lymphatics, Aqueous Humor, and Intraocular Pressure
Abstract: Lymphatic vessels are essential for regulating interstitial fluid balance, facilitating immune cell transport, supporting lipid absorption, and playing significant roles in tumor development and metastasis. Recent findings have expanded their recognized functions, particularly in pathological contexts. One notable discovery is the involvement of lymphatics in draining aqueous humor from the eye, a process closely linked to the regulation of intraocular pressure (IOP) and its implications for glaucoma progression. This review …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 31–44 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Exploring the Luminescent Behavior of Dysprosium-Doped Halo-sulphate Compounds
Abstract: In essence, this study aims toward understanding the photo-luminescent properties of Dy³⁺ halogenated sulfates, viz., synthesis, characterization, and luminescent behavior of the materials. Dysprosium ions are introduced into the halo-sulfate matrices to investigate their suitability for solid-state lighting applications. The aim of the study is to explain the mechanisms of the photo luminescence of Dy³⁺ and study the influence of the doping concentration on luminescence efficiency and the thermal stability …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 3, 2025 · pp. 01–06 Read article
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Long Non-Coding RNAs: Key Regulators of Gene Expression in Development and Disease
Abstract: Long non-coding RNAs (lncRNAs) are RNA molecules that do not make proteins but are essential for controlling how genes are turned on or off in the body. These molecules help with various biological functions, such as guiding cell growth, shaping development, and influencing the progression of diseases. Recent advancements in genomics and transcriptomics have revealed the vast and complex roles of lncRNAs, with an increasing recognition of their involvement in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 11–15 Read article
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Advanced Functional Nanocomposites: Graphene Oxide Integration into Polyvinyl Alcohol Matrix
Abstract: This research explores how incorporating graphene oxide (GO) into polyvinyl alcohol (PVA) can improve its mechanical and thermal characteristics, with the goal of creating multifunctional nanocomposites suitable for advanced technological applications. GO was introduced into the PVA matrix at 0.5, 1, and 2 wt% via a scalable solution casting method. The resulting nanocomposites were characterized mechanically, thermally, and spectroscopically. Tensile testing revealed a significant improvement in mechanical performance, with tensile …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 50–59 Read article
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Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Formulation and Evaluation of Herbal Anti-inflammatory oil using Tamarindus Indica oil, Vitex Negundo oil and Ipomoea batatas oil
Abstract: The formulation and evaluation of a herbal anti-inflammatory oil derived from the leaves of Tamarindus indica (Tamarind) Ipomoea batatas (Sweet potato) Vitex negundo (Nirgundi) aim to explore the therapeutic potential of these plants in managing pain and inflammation. Tamarind leaves are rich in flavonoids like quercetin, which primarily provide anti-inflammatory benefits by inhibiting pro-inflammatory cytokines, though their analgesic effects are moderate. Nirgundi leaves contain eugenol, known for its strong analgesic …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 01–06 Read article
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Mechanisms of Crystal Growth: From Spiral Steps to Surface Adhesion
Abstract: Crystal growth is a complex interplay between thermodynamic stability and kinetic processes, influenced heavily by the conditions under which crystallization occurs—particularly the degree of supersaturation. This abstract outline three principal regimes of solution-grown crystal growth: defect-driven, two-dimensional, and adhesive growth. At low supersaturation, growth is facilitated at surface defects, such as screw dislocations, where energy barriers to attachment are minimized. This results in the formation of spiraling steps that propagate …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 46–31 Read article
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Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Nanotechnology in Internet of Things: A Powerful Partnership Shaping the Future
Abstract: IOT holds potential to improve lives and revolutionize industries. However, its widespread adoption depends on addressing the growing energy consumption concerns. Nanotechnology provides a pathway to create a more energy-efficient IoT ecosystem by enabling the development of self-powered devices, low-power electronics, high-performance batteries, and advanced sensors. IoT is changing our daily lives and work by linking countless devices and producing vast amounts of data.. However, this explosive growth comes with …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 Read article
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Comparison Analysis of Transformer Boosting and Induced Degeneration Topology Design of LNA for Millimeter Wave Frequency Range Using Polymeric Substrates
Abstract: In this study, a comparison between transformer boosting and source degeneration LNA topologies is conducted using two polymeric substrates—Polyimide (PI) and Liquid Crystal Polymer (LCP)—for millimeter-wave (mmWave) applications. With growing interest in flexible and high-frequency electronics, polymeric materials offer unique advantages such as low dielectric constants, mechanical flexibility, and thermal stability. The analysis explores gain, return loss, and noise figure performance while evaluating the influence of dielectric properties on the …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 2, 2025 · pp. 1–24 Read article
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Comparison of Several Clinical Scoring Systems in Predicting the Outcome of Variceal Bleeding
Abstract: Background: Stratification of variceal bleeding patients into high-risk and low-risk group is very important to guide them through the suitable clinical pathway and to save the medical costs. We purposed to find out the best scoring system in the prediction of rebleeding and death after variceal bleeding by comparing four clinical scoring systems(clinical Rockall score, complete Rockall score, AIMS65 score, Child-Pugh score) which seemed to be applicable and simple. Method: …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 2, 2025 Read article
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Development of 3D Printing Filaments from Industrial Waste Plastics
Abstract: The global plastic waste crisis has prompted innovative approaches to sustainable material reuse, particularly in additive manufacturing. Simultaneously, the accumulation of plastic waste presents significant environmental concerns. Recycling plastic into filament supports eco-friendly innovation and brings us closer to a circular economy where materials are reused instead of thrown away. This study investigates the development of 3D printing filaments from industrial waste plastics, including polypropylene (PP), acrylonitrile butadiene styrene (ABS), …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 1, 2025 · pp. 12–17 Read article
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Crossroads of Ecology and Medicine: Evaluating Pollutant-Induced Risks to Biodiversity and Human Health
Abstract: Environmental pollution has emerged as a central challenge at the crossroads of ecology and human medicine. The rapid pace of industrialization, urbanization, and agricultural intensification has led to an unprecedented release of pollutants into the air, water, and soil—triggering cascading effects on ecosystems and human health. Pollutants such as particulate matter, heavy metals, pesticides, microplastics, endocrine-disrupting chemicals, and persistent organic pollutants not only degrade biodiversity but also exert multifaceted health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 41–53 Read article
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Impacts of Climate Change on Land Degradation: A Review of Mitigation
Abstract: Land degradation has emerged as one of the most pressing environmental challenges globally, significantly impacted by the multifaceted and escalating effects of climate change. The degradation of land, including soil erosion, nutrient depletion, deforestation, and desertification, directly threatens food security, biodiversity, and human livelihoods. As climate change leads to increasingly erratic weather patterns, including prolonged droughts, intense rainfall, and extreme temperatures, land degradation has become more pronounced and widespread, exacerbating …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 6–10 Read article
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Polymer-Based Materials in Green and Sustainable Construction
Abstract: The escalating impacts of global warming, driven by greenhouse gas emissions, demand urgent action in the construction sector, which contributes over 40% of global CO₂ emissions. Smart buildings, designed to optimize energy use, water efficiency, and occupant comfort through automation and advanced materials, represent a transformative response to these challenges. The convergence of sustainability and urban development has spotlighted the need for green materials in smart building design. With buildings …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 42–48 Read article
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The Role of Optimization and Probability in Shaping Artificial Intelligence
Abstract: This study discusses the basic roles of optimization algorithms and the theory of probability in the process of evolution and development of Artificial intelligence (AI). First, we introduce the role played by the next generation of leading-edge optimization algorithms developed since gradient descent to evolutionary strategies with respect to the learning of high-level AI models and how to enable them to learn to effectively explore high-dimensional parameter spaces. At the …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 123–128 Read article