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299 articles for “Formulation Development”
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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pH-Triggered In-Situ Nasal Gel Systems for Migraine Therapy: A Review
Abstract: Intranasal drug delivery has gained considerable attention as a non-invasive route for delivering drugs to both systemic circulation and the central nervous system, particularly for the treatment of migraine. Traditional nasal formulations such as sprays and drops often show poor therapeutic performance due to rapid mucociliary clearance and limited retention within the nasal cavity. To overcome these challenges, in-situ gel systems have been designed, which transform from a liquid to …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Fabrication and Characterization of Diacerein Loaded Nanosponge for Topical Delivery
Abstract: Diacerein, an anti-inflammatory drug, which comes under BCS class II, commonly used in treatment of osteoarthritis has limited by its poor solubility and bioavailability when administered topically. This study aimed to develop and evaluate diacerein-loaded nanosponges gel using varying concentrations of ethyl cellulose and polyvinyl alcohol (PVA) to enhance its delivery. Nanosponges were prepared using an emulsion solvent evaporation technique, with different ratios of ethyl cellulose (0.05-0.250%) and PVA (0.2-0.3%). …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 26–46 Read article
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Kinematic and Dynamic Modelling of a 6-DOF Robotic Manipulator for Industrial Applications
Abstract: The rapid evolution of industrial automation has intensified the need for highly accurate, flexible, and intelligent robotic systems capable of operating in dynamic and demanding environments. Among these systems, six-degree-of-freedom (6-DOF) robotic manipulators have emerged as a versatile solution due to their superior dexterity, large workspace, and human-arm-like motion capabilities. This research focuses on the comprehensive kinematic and dynamic modelling of a 6-DOF robotic manipulator designed for various industrial tasks …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 2, 2025 · pp. 27–32 Read article
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Tropical Medicine and Leishmaniasis: Unraveling the Complexities of a Neglected Tropical Disease
Abstract: Protozoan parasites of the genus Leishmania are the cause of the vector-borne disease leishmaniasis, which poses a serious threat to global public health in tropical and subtropical areas. Despite being common and having a significant effect on human health, leishmaniasis is still a neglected tropical disease, with little funding available for investigation and prevention. This article examines the relationship between leishmaniasis and tropical medicine, emphasizing the particular difficulties this intricate …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 29–39 Read article
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Oral Thin Films of Ondanetron Hcl: Formulation and Performance Evaluation
Abstract: This study had the goal to formulate oral polymeric thin film that would dissolve and disintegrate instantly, while also having high mechanical features. These are the most advanced forms of solid dosage forms. Solvent casting was the technique employed to create oral thin films. These are additionally referred to as buccal films/strip, mouth dissolving films, oral thin films, as well as oral strips of paper. These films are suitable for …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Analysis of Gold Price Trend Using the Hidden Markov Model
Abstract: This study aims to analyze the behavior of gold prices in India through a two-state Hidden Markov Model (HMM). We first formulated crucial parameters, such as the Transition Probability Matrix (TPM), Initial Probability Vector (IPV), and Emission Probability Matrix (EPM). Subsequently, we constructed a hidden Markov probability distribution and evaluated Pearson’s coefficients to gauge the correlations separately for each state. The goodness of fit of the developed model was assessed …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 2, 2024 · pp. 7–16 Read article
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Sustainable Green Solvents: Ionic Liquid-Based Hydrogels
Abstract: Green solvents have been widely used in a wide range of applications, such as catalysis, separation sciences, energy storage and pharmaceutical applications. The main ingredient in the collection of the environmentally benign reagents is ionic liquids (ILs). Ionic liquid-based hydrogels are being used in the biological sciences and medicinal chemistry fields because of their excellent biocompatibility and biosafety features. The versatility of ionic liquids is great, as they can be …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1263–1274 Read article
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Diet(Nutrition) Recommender using Machine Learning
Abstract: In an era where maintaining a healthy lifestyle has become a priority, personalized dietary recommendations play a crucial role in guiding individuals towards achieving their nutritional goals. The Diet Recommendation System is an inno- vative application that combines user-specific data with machine learning algorithms to provide tailored dietary suggestions. This system is designed to simplify the process of meal planning and promote healthier eating habits. The Diet Recommendation System is …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Metals and Minerals in Pharmacy: Current Trends, Biomedical Applications, and Future Innovations
Abstract: Metals and minerals have played important roles in medicine for centuries, ranging from the use of simple mineral powders in traditional therapies to the development of modern metal-based drugs and nanomaterials. In recent years, advancements in material science, nanotechnology and pharmaceutical engineering have expanded the biomedical relevance of inorganic materials far beyond their conventional use as excipients. This review highlights the growing integration of metallic and mineral systems into pharmaceutical …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 12–24 Read article
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Controlled Drug Delivery of Furosemides Using Floating Tablet System
Abstract: The development of gastroretentive drug delivery systems (GRDDS) has gained interest, particularly for drugs like furosemide with narrow absorption windows in the upper gastrointestinal (GI) tract. Furosemide, a commonly used diuretic, faces challenges due to limited bioavailability and rapid elimination, requiring frequent dosing and affecting patient compliance. This review highlights the formulation and evaluation of floating furosemide tablets as an effective strategy to enhance therapeutic efficacy. Floating tablets allow prolonged …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 23–31 Read article
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Machine Learning-Assisted Design and Optimization of Lightweight Polymer Composites for IoT-Enabled Automotive Applications
Abstract: This study aims to develop an integrated machine learning and optimization framework for the intelligent design of lightweight polymer composites suited for IoT-enabled automotive applications. The goal is to enhance material performance while satisfying multiple design constraints such as mechanical strength, thermal stability, and process compatibility. A curated dataset of polymer composite formulations was used to train a Random Forest Regression (RFR) model capable of predicting tensile strength, thermal conductivity, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 12–27 Read article
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Exploration of Diverse Epoxy-Based Surface Coating Methods for Enhancing Anticorrosion Characteristics
Abstract: Epoxy-based polymers, commonly referred to as polyepoxides, constitute one of the most versatile and widely adopted categories of polymeric materials due to their exceptional structural, mechanical, and chemical characteristics. Their unique macromolecular framework enables strong interfacial bonding, high mechanical stability, and superior resistance to environmental and chemical degradation, positioning them as advanced alternatives to many traditional organic corrosion inhibitors that often fail under prolonged exposure to aggressive conditions When polyepoxides …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 167–177 Read article
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Cow’s Milk Allergy: Prevalence, Diagnosis, and Alternative Formulations
Abstract: Cow’s Milk Allergy (CMA) occurs when the immune system reacts to proteins in cow’s milk, like casein and whey. In individuals with CMA, the immune system wrongly perceives these proteins as threats, causing allergic reactions when cow’s milk is consumed. Unlike lactose intolerance, which results from the body’s inability to digest lactose – a sugar in milk – due to a deficiency of the enzyme lactase, CMA is an immune …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 22–26 Read article
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Impact of HIV on Global Health: A Comprehensive Review of Epidemiology and Interventions
Abstract: H.I.V remains a significant health issue of great concern to the world and with great impact to the individuals and communities on a global scale. This is a comprehensive literature review on the epidemiology of HIV, including both the world prevalence of HIV and the regional variations, especially in sub-Saharan Africa. It discusses the most important modes of transmission including sexual, blood, and vertical transmission and investigates the effectiveness of …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 39–45 Read article
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Prediction of Depth-Induced Stress Distribution and Maintenance Cost Implications for Submerged Structural Components
Abstract: This study investigates the influence of water depth on stress distribution and structural integrity of submerged mechanical components . Structural models fabricated from mild steel, stainless steel, carbon steel, and copper alloy were examined under hydrostatic loading corresponding to water depths between 30 cm and 150 cm. Results indicate that normal and shear stresses increased proportionally with depth due to intensified hydrostatic pressure. Mild steel exhibited the highest stress concentrations, …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 2, 2025 · pp. 29–35 Read article
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Design and Performance Evaluation of PLA-based Umbrella Wheels for Stair-Climbing Robotic Applications
Abstract: Staircase climbing robots require a complex design capable of navigating various stair configurations. A crucial component of such robots is the wheel mechanism. This paper focuses on the umbrella wheel mechanism and its application in staircase climbing robots. In this study, a PLA–based umbrella wheel structure is developed and fabricated using fused deposition modeling (FDM) for application in stair-climbing robots. The umbrella wheel geometry enables transformation from a circular rolling …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 808–824 Read article
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The Therapeutic and Biotechnological Potential of : Pogostemon benghalenesis, A Comprehensive Review
Abstract: Pogostemon benghalensis is a fragrant perennial shrub belonging to the family Lamiaceae, widely distributed across tropical and subtropical regions of Asia. It has been extensively utilized in traditional and ethnomedicinal systems for the treatment of wounds, skin infections, fever, digestive disorders, inflammation, and respiratory ailments. The plant is also valued for its antiseptic, aphrodisiac, insect-repellent, and veterinary medicinal properties. Its leaves, roots, and essential oil are incorporated into herbal formulations, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 Read article
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Intuitionistic Fuzzy Hypergraph Laplacians and Dominating Transversals for Resilient Discrete Network Design
Abstract: This manuscript develops a discrete mathematical framework for resilience analysis on networks whose interactions are polyadic, uncertain, and partially conflicting. Classical graphs compress multi-way coordination into pairwise edges, while ordinary fuzzy graphs often ignore the non-membership information that becomes critical in emergency logistics, infrastructure interdependence, and cyberphysical coordination. We therefore formulate an intuitionistic fuzzy hypergraph in which each vertex hyperedge incidence carries membership, non-membership, and hesitation, and we construct a …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 13, Issue 2, 2026 · pp. 15–21 Read article
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A Brief Review on Dissolution Simulation Software
Abstract: Pharmaceutical industries frequently use simulation software with real-time responses for a variety of purposes, such as dissolution simulation. In essence, it is a tool that lets the user to simulate an operation and see it happen without actually conducting it. Equipments are frequently designed using simulation software to ensure that the finished output will be as near as to the design specifications as possible without costly process adjustments. Advanced computer …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 1–11 Read article