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217 articles for “pathogenic infection”
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COVID-19: Impact on Human Health
Abstract: Researchers are on the cutting edge of devising the best strategy to combat the SARS-CoV-2 pandemic by studying and exploring the pathogenesis, prevention, and treatment as the world continues to be plagued by an increasing number of confirmed COVID-19 cases. The primary method for detecting the virus is via antigen testing and more accurate molecular tests such as rt PCR using patient samples. The most prevalent treatments for COVID-19 infection …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 1–8 Read article
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Genomic Characterization of Emerging Arboviruses in Rural India
Abstract: Arboviruses (arthropod-borne viruses) represent a rapidly evolving group of pathogens responsible for significant morbidity and mortality, particularly in tropical and subtropical regions. Rural India, characterized by dense vector populations, changing ecological patterns, and limited healthcare infrastructure, has become a hotspot for the emergence and re-emergence of arboviral diseases such as dengue, chikungunya, Japanese encephalitis, and more recently, Zika virus infections. Advances in genomic technologies, including next-generation sequencing (NGS), metagenomics, and …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 · pp. 1–8 Read article
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The Evolution of Asthma Management: A Comprehensive Analysis of GINA 2024 Guidelines, Endotype-Driven Diagnosis, and Targeted Biologic Intervention
Abstract: Asthma remains a substantial global public health challenge, characterized by heterogeneous airway inflammation leading to variable airflow obstruction. Recent advances in personalized medicine and guideline revisions, notably the Global Initiative for Asthma (GINA) 2024 update, mandate a profound paradigm shift from reliance on short-acting beta2-agonists (SABA) to antiinflammatory reliever (AIR) strategies utilizing inhaled corticosteroid (ICS)-formoterol. This report provides an exhaustive analysis of current asthma epidemiology, molecular pathogenesis distinguishing between Type …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 Read article
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Diseases among Sewage Workers
Abstract: Urbanization has caused many health and environmental problems; to solve some of these problems, latrines and sewage systems were invented and are still being improved. This development has resulted in exposures of the sewage workers to the multitude of chemicals used in our homes and in the industries. With increasing demands on the sewage systems and new environmental regulations, the transportation and treatment of wastewater has increased in technical complexity. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 3, 2016 · pp. 1–5 Read article
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The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
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Review on Advanced Molecular Diagnostic Tools and Their Applications
Abstract: Although the diagnosis of diseases is still primarily based on conventional methods (staining, culture, biochemical analysis), a series of advanced molecular diagnostic tools are increasingly introduced and incorporated in the workflow of clinical laboratories worldwide. These tools, such as polymerase chain reaction, northern blotting, restriction length polymorphism, flow cytometry, southern blotting, fluorescent in situ hybridization, agarose gel electrophoresis and pyrosequencing that are based on either the properties of nucleic acids …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 3, 2013 · pp. 21–33 Read article
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Synthetic Viruses: A Review
Abstract: Fast advance in DNA synthesis and sequencing is leading the deliberate, large-scale hereditary change of organisms. Common objective of this new methodology is to advance our understanding of an organism's properties, especially its pathogenic ordnance in the event that it causes illness in people, and to make utilization of this new data to shield from, or treat, human viral disease. These new advances in DNA control have been stretched out …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 1, 2018 · pp. 28–34 Read article
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Universal Immunization Program in India
Abstract: The Universal Immunization Program (UIP) in India, initiated by the Government of India in 1985 and incorporated into the Child Survival and Safe Motherhood Program in 1992, plays a crucial role in enhancing public health through systematic vaccination efforts. This program aims to save lives and strengthen immune systems by administering vaccines and antibiotics. The UIP has spurred the development of various campaigns, including mass media efforts, to promote immunization …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 24–30 Read article
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Antibacterial and Antifungal Activities of Mirabilis jalapa of Indian Origin
Abstract: The in vitro antimicrobial activity of Mirabilis jalapa leaf extract was studied against selected pathogenic and non-pathogenic microorganisms Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, Penicillium chrysogenum, Auriparus flaviceps and Trichoderma viridae by using agar diffusion and broth dilution methods. Leaves were extracted using solvents petroleum ether, chloroform and methanol. Among the solvents tested, petroleum ether and chloroform extracts showed good antimicrobial activity against the selected pathogens. The growth inhibitors were …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 2, Issue 2, 2012 · pp. 1–10 Read article
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Management of Kosthasakhashrita Kamala W.S.R. to Hepatocellular Jaundice – A Case Study
Abstract: Kosthasakhāśrit Kamala is a well-recognized clinical entity in Ayurveda and is widely correlated with modern hepatocellular jaundice. The condition arises primarily due to the vitiation of Pitta dosha within the Kostha (gastrointestinal tract), which subsequently spreads to the Sakha (peripheral tissues). Classical texts describe hallmark features such as Haridra Netra (yellowish discoloration of the eyes), yellowish hue of twak and nakha, pitta varṇa of mutra and sakrit (yellow urine and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 1–8 Read article
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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The Biogenesis, Transmission, Structural and Therapeutics on SARS-CoV-2 (COVID-19) Pandemic: Challenges and Global Perspective
Abstract: The present pandemic situation due to the appearance of COVID-19 has put the world in a miserable condition. About 2.5 million people have been infected with the strain of coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) globally. The foremost patient of COVID-19 infection was identified in China in the month of December 2019. Researchers are searching for an effective method to combat this pandemic virus. The investigations have been regulated …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 24–39 Read article
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Artificial Intelligence In Transfusion Medicine And In Our Mission To “BEAT- COVID”
Abstract: The key objectives of this manuscript are: 1] Demystifying the buzzword of Artificial Intelligence [AI] and comparing neuronal networkings similarity of machines with some mammals; 2] Exploring, from outside sources, the breath of some computerized procedural data generated in laboratory and clinical areas of medicine, by robotic tools in the cutting age of transfusion medicine; 3] Expressing views on the variabilities of covid- associated long lasting microcirculatory disseminated pathogenic autoimmune …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 7, Issue 3, 2020 · pp. 10–21 Read article
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Anti-Escherichia coli Potentials of a Novel Chemical Compound 1-(2-hydroxy-1, 2-diphenylethylidene)-3-phenylthiourea
Abstract: Inspiration from the anti-infective excellence (anti-bacterial, anti-fungal, anti-viral, and anti-malarial) of Schiff’s base molecules as well as knowing the rising importance of low-molecular-weight ligands (LMWL), the present research involved the development of novel Schiff’s base compound utilizing very basic laboratory components; 1-phenylthiourea and benzoin using the conventional synthesis technique. The compounds were comprehensively characterized through sophisticated instruments and further screened for anti-microbial activity against pathogenic Escherichia coli (E. coli, MTCC …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 9–12 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
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Pathways of Periodontal Disease and Alveolar Bone Loss in Type II Diabetes
Abstract: or poorly-controlled type II diabetes often exhibits a high morbidity of periodontal pathology. Food impaction in defective restorations or open proximal contacts often leads to infection, carious lesions, periodontitis, alveolar bone loss and often tooth loss. An iatrogenic injury occurs when restorations are defective, fractures, or have open proximal contacts and are not planned to be repaired or replaced. In addition to having poor therapeutic outcomes, defective restorations or open …
Published in Research and Reviews: A Journal of Dentistry · Vol. 4, Issue 3, 2013 · pp. 28–35 Read article
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Viral Chronicles: The Ever-Evolving Saga of COVID-19
Abstract: Coronaviruses, belonging to the family of RNA viruses, have recently captured global attention owing to their remarkable ability to infect a diverse array of species, ranging from animals to humans. These viral agents, recognized by their characteristic crown-like morphology when observed through electron microscopy, have a historical association with zoonotic diseases. Previous examples include Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The term "Corona" …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 16–25 Read article
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Effects of Smoking on Respiratory System
Abstract: Smoking is whispered to exacerbate respiratory diseases by harming respiratory defense mechanisms. Specifically, smoking damages mucociliary function, which impairs clearance of inhaled substances even in smokers who have no respiratory symptoms promotes bacterial adherence to airway epithelial cells. The devastating health impact of cigarette smoking is well known, Cigarette and its components produce structural changes in the respiratory tract include peri-bronchiolar inflammation and fibrosis, augmented mucosal permeability, destruction of the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 5–8 Read article
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Anti-infective Investigations of Methanolic Extract and Petroleum Ether Extract of Ixora coccinea L. Flowers
Abstract: Ixora is an evergreen flowering tropical plant belonging to the family Rubiaceae. It is commonly found in India, the United States of America, Africa, South East Asia, and Southern Asia. Across the globe, several species (Ixora coccinea, I. parviflora, I. chinensis, I. macrothyrsa, I. javanica, and I. finlaysoniana) of this genus have been identified so far. After going through the literature available in pharmaceutical databases, it was found that the …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 2, 2020 · pp. 17–23 Read article
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Evaluation of Fungicides and Bioagents against Pyricularia grisea in vitro
Abstract: AbstractBlast disease, a standout amongst the most pulverizing infections of rice in most rice delivering regions of the world is caused by Pyricularia grisea [1]. In Nepal, the infection causes 10–20% yield diminishment in vulnerable assortments, however in extreme case; it goes up to 80% [2]. Chemicals are ordinarily connected for controlling rice impact sickness [3], yet when chemicals are utilized aimlessly, they likewise represent a genuine risk to the …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 6, Issue 1, 2017 · pp. 33–36 Read article