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304 articles for “chronic”
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In Silico Analysis and Molecular Docking Studies of COX-2 Inhibitors for Anti-Inflammatory Activity
Abstract: Although nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used to treat pain, lower fevers, and control inflammation, they frequently cause gastrointestinal side effects because they inhibit the COX-1 and COX-2 enzymes. Despite their effectiveness and lack of gastrointestinal side effects, selective COX-2 inhibitors have been linked to cardiovascular risks. To find new COX-2 inhibitors that are safer and more effective, this study uses in silico techniques, such as molecular docking and …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 38–55 Read article
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A Review: Homeopathic Remedies and Their Potential Neurological Implications in Depression and Asthma
Abstract: Homeopathy, based on the principle “like cures like”, has gained popularity as a complementary treatment for chronic diseases, including depression and asthma. Both health conditions have a profound impact on the quality of life of individuals and are often treated with pharmacological interventions such as antidepressants and bronchodilators. This review reviews homeopathic remedies used to treat depression and asthma, evaluating the available clinical evidence. Although some studies suggest that homeopathy …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 15–20 Read article
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A Comprehensive Review of Alternative Medicine: Biological Plausibility, Testability, Repeatability, and Effectiveness
Abstract: Alternative medicine, encompassing practices, such as acupuncture, herbal remedies, homeopathy, chiropractic care, Ayurveda, and Traditional Chinese Medicine (TCM), has gained global popularity as patients seek non-conventional healthcare solutions. Despite its widespread use, scientific evaluation of its biological plausibility, testability, repeatability, and effectiveness remains a significant challenge. This review critically examines these four criteria to assess the validity and reliability of alternative therapies. Acupuncture demonstrates partial plausibility, with evidence suggesting its …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 32–46 Read article
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Clinical Evaluation of Ayurvedic Intervention (Mahamanjishathadi Kwatha, Kaishora Guggulu, Panchatikta Ghrita, Eranda Taila) in the Management of Ekakushtha W.S.R. to Psoriasis
Abstract: Introduction: Psoriasis is a chronic skin condition causing scaly plaques, typically on extensor surfaces, scalp, and nails, and often leads to quality of life impairments, including physical and mental health challenges. Ayurveda offers a holistic approach targeting root causes and balancing body and mind, while conventional treatments focus on symptom management through therapies that may cause side effects and recurrence. Aim and Objectives: The study aimed to assess the efficacy …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 Read article
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Calotropis: A Comprehensive Review of Its Phytochemistry, Pharmacology, and Therapeutic Potential
Abstract: Calotropis gigantea is a genus in the family Apocynaceae that grows in tropical and semitropical climates. India is home to this plant’s distribution. In Hindi, it is referred to as sweta arka. It is well known for its medicinal and ethnobotanical values. Calotropis gigantea, in particular, has a history of use in the treatment of many health-related issues, including disorders of the respiratory system, inflammation, and skin infections. Calotropis gigantea …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 6–20 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Exploring Herbal Treatment: A Comparative Review of Their Efficacy in Rheumatic Arthritis
Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory disease that mostly affects the joints but can potentially have systemic consequences across various orggan. Traditional treatments such as Disease-Modifying Antirheumatic Drugs (DMARDs) and Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) provide symptom relief but may cause side effects with varying severity long- termuse. Recent interest has emerged in herbal plants with anti-inflammatory properties, which have been used historically in Ayurvedic and Unani medicine. This review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 2, 2025 · pp. 13–21 Read article
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Effect of 4-Week Protocol of Kegel Exercise on Pelvic Floor Strength on a Patient with Ovarian Endometriosis—A Case Report
Abstract: Purpose: The purpose of this case study was to describe the effects of Kegel exercise in a 4-week protocol for a patient with endometriosis associated with urinary incontinence. Case description: A 23-year-old female patient presented with chronic low back pain and also complained of difficulty in holding urine and leakage while doing forceful activities like lifting heavy objects, coughing, and sneezing in the past 6 months. She also complained of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Understanding Metabolic Syndrome and its Nutritional Management
Abstract: Metabolic syndrome (MetS) is a collection of risk factors, especially when at least three occur together, including abdominal obesity, dyslipidemia, low high-density lipoprotein cholesterol (HDL-c) levels, hypertension, and insulin resistance. MetS is linked to an increased risk of diabetes and cardiovascular diseases (CVDs) if treatment is not received.The causes of MetS include both genetic and acquired factors that contribute to issues such as insulin resistance, chronic low-grade inflammation, and obesity. …
Published in International Journal of Sustainability · Vol. 2, Issue 1, 2025 · pp. 26–37 Read article
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IoT-Based Automated Medication Management System
Abstract: An Internet of Things (IoT)-based automated medication dispenser with an integrated alert system is presented in this research. The device is managed by an ESP32 microcontroller, which is paired with a Real-Time Clock (RTC) module to ensure medication is dispensed at the correct time. To facilitate the dispensing process, the system uses servo and stepper motors to rotate the medication carousel and release the appropriate dosage. To determine whether the …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 1, 2025 · pp. 16–21 Read article
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Effectiveness of Moist Heat Application on Elderly Orthopedic Clients at Selected Urban Community Area, Bengaluru
Abstract: Pain is a distressing sensory and emotional experience that arises from actual or potential tissue damage. It is a multifaceted phenomenon that extends beyond physical discomfort, encompassing emotional and psychological aspects as well. Individuals who recognize that pain management not only enhances comfort but also accelerates the healing process are more inclined to seek or administer appropriate treatment. In order to educate the elderly orthopedic clients, this study was conducted …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 18–22 Read article
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Swastham: The Healthcare Ecosystem
Abstract: In the modern, fast-paced world, ensuring prompt and efficient healthcare services has become more crucial than ever. The demand for accessible, timely, and high-quality healthcare is constantly growing, and this project seeks to address this need by introducing a comprehensive healthcare ecosystem. This integrated platform is designed to optimize healthcare delivery and significantly enhance patient outcomes by incorporating advanced digital solutions. The system will allow users to conveniently schedule appointments …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 01–07 Read article
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Erythrodermic Psoriasis: A Case Report Highlighting Clinical Features and Management
Abstract: Background: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis that presents as widespread erythema, scaling, and systemic complications such as fever, dehydration, and electrolyte imbalances. It requires urgent medical attention due to the risk of life-threatening complications, including sepsis and multi-organ failure. The condition can arise de novo or as an exacerbation of pre-existing psoriasis, often triggered by medication withdrawal, infections, or systemic inflammation. Case Presentation: We …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 01–05 Read article
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Evaluation of Medication Adherence in Patients with Type 2 Diabetes Mellitus: A Mixed- Methods Approach
Abstract: Background: Medication adherence refers to how closely an individual follows the prescribed medication regimen. It is essential for achieving desired therapeutic outcomes and improving patient health. Inadequate adherence can result in the deterioration of health conditions, higher mortality rates, and increased healthcare expenses. Diabetes mellitus, being a chronic condition, demands ongoing medical care not only to prevent the onset of serious complications but also to manage them effectively once they …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–35 Read article
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A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)
Abstract: The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 102–110 Read article
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The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article
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Empowering Rural Healthcare in Tamil Nadu: A Framework for Patient-Centered Telemedicine
Abstract: Rural populations in Tamil Nadu often face challenges in accessing quality healthcare due to geographic isolation, limited resources, and shortages of healthcare professionals. Telemedicine has emerged as a transformative solution, offering a promising approach to bridge these gaps. This article presents a comprehensive framework for patient-centered telemedicine aimed at empowering rural healthcare in Tamil Nadu. By focusing on chronic disease management, particularly for conditions like hypertension and diabetes, this framework …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 36–42 Read article
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A Review of Nanotechnology Application in Pharmaceutical and Health Care
Abstract: Nano drug and nano delivery systems are a fairly new but fleetly developing wisdom where accoutrements in the nanoscale range are employed to serve as means of individual tools or to deliver remedial agents to specific targeted spots in a controlled manner. Nanotechnology provides numerous advantages in treating chronic diseases by enabling precise, site-specific, and targeted drug delivery. Recently, there have been several remarkable applications of nanomedicine, including chemotherapeutic agents, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 07–17 Read article
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Predicting Multiple Diseases Using Machine Learning: A Data-Driven Approach
Abstract: The increasing prevalence of chronic and life-threatening diseases highlights the need for innovative healthcare solutions that enable early detection and proactive management. The Multiple Disease Prediction Platform is a web-based system utilizing machine learning (ML) and deep learning (DL) algorithms to analyze user-inputted health data, generating real-time predictions of potential health risks. By leveraging Python’s Streamlit library, the platform provides an interactive and accessible diagnostic experience, eliminating the need for …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 16–35 Read article