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575 articles for “Novel methods”
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Alzheimer’s Disease Detection Using ML Algorithm
Abstract: A degenerative neurological state of affairs, Alzheimer's disease (AD) gradually impairs cognitive and functional capacities, especially in people over 65. Early AD detection is crucial for efficient management and treatment prep. This study delves into novel approaches for the early detection of AD using non-invasive methods. We've implemented a blend of neuroimaging data analysis and machine learning algorithms to pinpoint markers indicative of the disease during its initial phases. Our …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 53–57 Read article
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Development of a Novel Analytical Framework for Investigating Non-Symmetric Deformation Behavior in Strip Rolling
Abstract: In recent years, the asymmetrical rolling process has attracted considerable research attention due to its ability to induce non-uniform deformation characteristics within metallic workpieces. In this context, the present study introduces a novel analytical framework for asymmetrical cold rolling based on an enhanced slab method, specifically designed to overcome the inherent limitations of existing analytical models when applied to a wide range of asymmetric rolling conditions. A newly developed mathematical …
Published in Journal of Experimental & Applied Mechanics · Vol. 17, Issue 1, 2026 · pp. 1–21 Read article
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Developing an Assessment Protocol in Ayurvedic Research for Hyperemesis Gravidarum with Special Reference to Garbhini Chardi
Abstract: Garbhini Chardi (nausea and vomiting in pregnancy) is described in Ayurvedic texts as one of the Vyakta Garbha Lakshanas – early physiological signs indicating pregnancy. However, when this symptom becomes excessive, persistent, or distressing, it may transition from a normal event to a pathological condition, requiring timely intervention to safeguard maternal and fetal health. In advanced stages, it leads to day-to-day incapacitation, weight loss, dehydration, and metabolic disturbances – clinically …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 44–61 Read article
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Mechatronics Robot Navigation using Machine Learning through Prolog Programming Language
Abstract: A basic decision-making system is developed in this paper using Neural Network in Machine learningto explore a robot in concealed condition. The robot can move out of explicit labyrinths effectivelythrough modifying its bearing and speed persistently via the neural system model for machinelearning. Over the past several years, navigation tasks for mobile robots have been widely studied.There have been many attempts to introduce the usage of machine learning algorithms. Excellentperformance …
Published in Journal of Mechatronics and Automation · Vol. 8, Issue 1, 2021 · pp. 39–47 Read article
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Synthesis and Characterization of m-Amino Pyridine Derivatives
Abstract: Background: The current study involves the synthesis and characterization of amino derivatives. In the current research study, a series of m-amino pyridine derivatives were synthesized using m-amino pyridine and carbonyl compounds and characterized further. The pyridine derivatives have shown to possess potent antibacterial, antifungal, antitumor, antimalarial, anti-inflammatory antidiabetic, antioxidant, anthelmintic, anticonvulsant, antituberculous and so many other properties. Method: The condensation reaction of m-amino pyridine and carbonyl derivatives with ethanol is …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 1–6 Read article
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Mitigation of Mobile Radio Parasitic Radiation Effects: A Review
Abstract: ABSTRACT In this paper, mitigation techniques useful for improving mobile radio systems power efficiency and decreasing electro-smog and specific absorption rate (SAR) induction, affecting human head and body, are presented. An analysis of main radiation effects from far field base stations and review of mitigation techniques for enhancing the efficiency of power transmission for mobile radio systems is shown, followed by an investigation of the complex radiation field components from …
Published in Journal of Communication Engineering & Systems · Vol. 2, Issue 1, 2012 · pp. 1–12 Read article
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Exhaustive Search Meets DNA Sequencing: A Comprehensive Review of TSP-Based Approaches
Abstract: Exhaustive search is a highly computational complex algorithm that checks every possibility to obtain the best solution. We illustrate an exhaustive search by applying it to three important problems: the traveling salesman problem, the knapsack problem, and the assignment problem. In this paper, we took a traveling salesman problem to explain DNA Sequencing. Since traveling salesman problem is an algorithmic problem that finds the shortest route between a set of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 11–21 Read article
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Secure Snap: Fortifying Image Preservation with a Robust Backup System
Abstract: The importance of implementing a robust backup system lies in preserving critical files against unforeseen events such as system crashes, hardware failures, or natural disasters. Data security plays a pivotal role in safeguarding confidential and vital information. Therefore, it is imperative for backup systems to prioritize security measures. Encryption emerges as a widely adopted method in today's industry to ensure data confidentiality. This project presents a novel computer software that …
Published in Journal of Instrumentation Technology & Innovations · Vol. 13, Issue 1, 2023 · pp. 17–22 Read article
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Wasteland Management and Quality of Ground Water in Swarnamukhi River Basin, Chittoor District, Andhra Pradesh: A Case Study
Abstract: The present study, the identification and development of wastelands in Swarnamukhi basin in Chittoor district of Andhra Pradesh, is based on primary survey of wastelands. In this study, the main stress is on the different reclamation and utilization methods to use wastelands, which are of complex in nature. It is a novel experiment. It is not just a study of the problem, which closes with suggestions and recommendations but represents …
Published in Journal of Remote Sensing & GIS · Vol. 6, Issue 3, 2015 · pp. 52–64 Read article
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Formulation and Evaluation of Curcumin Loaded Transferosomal Nasal In-Situ Gel for Alzheimer’s Disease
Abstract: Objective: To develop a novel delivery of curcumin by formulating its transfersome into nasal in situ gel. Methods: Curcumin transfersomes were prepared by thin film hydration method. Optimization of the formulation was performed using Design Expert software. Formulation and characterization of optimized batch of curcumin transfersomes were performed. The nasal in situ gel was prepared by incorporating the optimized transfersome. Results: The pH, drug content, in-vitro drug release profile and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 2, 2019 · pp. 19–31 Read article
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Drug Delivery Systems and Innovations
Abstract: The aim of this study was to develop a controlled release system targeting antibiotic distribution to the stomach. The hydrogels were synthesized by utilizing chitosan, poly(acrylic acid) and poly(vinyl pyrrolidone) polymers cross linked with glutaraldehyde and N,N′-methylene bisacrylamide. Interpenetrating polymeric network (IPN) hydrogels were compare by varying the concentration of crosslinking agent (glutaraldehyde). The amount of chitosan, poly(acrylic acid), poly(vinyl pyrrolidone) and N, N’-methylenebisacrylamide were kept constant in all formulations. …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 10–20 Read article
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Fractional Homotopy Analysis Transform Method for a Fin Having Temperature Dependent Internal Heat Generation
Abstract: Fractional Homotopy Analysis Transform Method (FHATM) is a new analytical tool for solving homogeneous and non-homogeneous fin equations. FHATM is a novel and innovative modification in Laplace Transform Algorithm (LTA) thus making analysis easier. Non-linear problems are solved by proposed technique without using Adomian and He’s polynomial which is a clear benefit of this new algorithm over decomposition and homotopy perturbation transform methods. This is an elementary technique which gives …
Published in Journal of Experimental & Applied Mechanics · Vol. 10, Issue 1, 2019 · pp. 23–34 Read article
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The Development and Characterization of Orodispersible Tablet using Novel Natural Superdisintegrant Polysaccharide Isolated from Cassia tora Seeds
Abstract: The present work is aimed at the development and characterization of orodispersible tablet using novel natural super disintegrant, a polysaccharide isolated from Cassia tora seeds. Metformin hydrochloride (HCL) tablets were prepared separately using different concentration (2%, 5%, 7.5%) of isolated Cassia tora seed, a natural polysaccharide and croscarmellose sodium (synthetic) as super disintegrant by direct compression method. Evaluation of the tablet was done for various pre and post-compression parameter. Development …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 24–31 Read article
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A novel approach based on Genetic Algorithm for High Dynamic Range Image
Abstract: In this paper, for the purpose of acquiring ghost free high dynamic range (HDR) pictures, we introduce another methodology which is taking into account genetic algorithms. It is the combination of numerous pictures which is in view of HDR system, just on condition is utilized for work which is no development of an article and the camera when catching various, differently exposed low dynamic range (LDR) pictures. Makes three LDR …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 2, Issue 3, 2015 · pp. 20–29 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Size-biased Sujatha Distribution with Properties and Application to Model Flood Data
Abstract: In this study, a size-biased version of the Sujatha distribution was proposed to model flood data. The descriptive statistical properties based on moments and the reliability properties of the distribution are discussed in detail along with their derivation and graphical presentation. An interesting feature of the proposed distribution is that it is a member of the exponential family of distributions. A sequential probability ratio test was performed using the proposed …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 1, 2024 · pp. 31–46 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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A Majority Function Based Full Subtractor
Abstract: In the present landscape of very large-scale integration (VLSI) technology, the imperative to implement Boolean functions with minimal gate count remains a cornerstone of efficient circuit design. This pursuit has only grown more critical with the evolution of low-power design strategies, which now offer significantly enhanced benefits compared to traditional approaches. The trifecta of performance, affordability, and dependability continue to drive innovation in this field, shaping the trajectory of technological …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 2, 2024 · pp. 8–14 Read article
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Polymer-Coated Composite Granules of Clarithromycin: Design, Characterization, and Functional Evaluation for Taste Masking and Antibacterial Performance
Abstract: Background: Masking the unpleasant taste of clarithromycin is essential to improve patient adherence, especially among pediatric and elderly groups. However, enhancing palatability while maintaining its antibacterial effectiveness remains a significant formulation challenge. This study focused on developing polymer-coated clarithromycin granules (B1–B10) using novel non-sugar-based polymers and assessing their antibacterial activity against Staphylococcus aureus Methods: Clarithromycin granules were produced using a fluidized bed coating technique with non-saccharide polymers, specifically Eudragit E-100 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1042–1050 Read article