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494 articles for “Validation Study”
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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A comprehensive study on elemental analysis and sustainable integration of CETP (common effluent treatment plant) sludge as a substitute to sand in concrete
Abstract: This study examines the utilization of sludge from common effluent treatment plants (CETP) as a fractional substitute for sand in M20 concrete mixtures. Its aim is to address disposal challenges associated with CETP sludge while promoting sustainable use of natural resources. The research assesses the structural and microstructural attributes of concrete mixes containing varying percentages of CETP sludge (0%, 10%, 20%, 30%, 40%, and 50%). Tests conducted include compressive, flexural, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 49–59 Read article
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Finite Element Formulation for Mechanical Buckling of FGM Plate Exposed to Various Boundary Conditions
Abstract: Mechanical buckling analysis of functionally graded (FG) material plates based on first-order shear deformation theory. In the real world many components manufactured by FG materials face the buckling load under certain conditions. Various types of gradation law for tailoring the material properties are applied by the researcher, out of that, presently a simple power law for material gradation is applied with shear correction factor (SCF) is used to take account …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 503–513 Read article
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Dr. Somenath Dutta, Discoverer of Micro-RNA (MiRNA) Therapeutic to Prevent Harmful Zika Virus for Liver Cancer: A Scientometric Portrait
Abstract: Dr. Somenath Dutta allies Rahul is a global recognized scientist for his outstanding recent discovery of “miRNA therapeutics for the Zika virus” at the age of 26 years, which can be cured Liver Cancer and allied health problems due to Zika virus disease. This study covers his 12 publications in variety of forms including 07 journal articles (59%), 03 conference papers (25%), 01 dissertation, and 01-chapter paper during 2019-2024. All …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 22–36 Read article
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Kinematic and Dynamic Modelling of a 6-DOF Robotic Manipulator for Industrial Applications
Abstract: The rapid evolution of industrial automation has intensified the need for highly accurate, flexible, and intelligent robotic systems capable of operating in dynamic and demanding environments. Among these systems, six-degree-of-freedom (6-DOF) robotic manipulators have emerged as a versatile solution due to their superior dexterity, large workspace, and human-arm-like motion capabilities. This research focuses on the comprehensive kinematic and dynamic modelling of a 6-DOF robotic manipulator designed for various industrial tasks …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 2, 2025 · pp. 27–32 Read article
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From Baseline Survey to Management Plan: A Systematic Framework for Port-Specific Mitigation of Underwater Radiated Noise
Abstract: The growing recognition of underwater radiated noise (URN) as a significant marine pollutant necessitates the development of actionable management frameworks at the port level, where noise sources are concentrated, and impacts can be particularly acute. While international guidelines exist, a standardized methodology for ports to transition from assessment to implementation is lacking, particularly in regions with high biodiversity and developing maritime infrastructure. This paper presents and demonstrates a systematic, four-phase …
Published in Journal of Offshore Structure and Technology · Vol. 13, Issue 1, 2026 · pp. 22–30 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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Application of pET28a Vector for the Over Expression of Recombinant Human Tim23 Protein in E. coli and its Validation by Immunoblotting
Abstract: This study aimed to produce recombinant human Tim23 protein by molecular cloning, expression, and purification. Amplification of human TIM23 was carried out by polymerase chain reaction (PCR) and cloned into DH5α cells. The pET28a-human TIM23 was transformed into BL21DE3 and expressed the gene by IPTG induction. Recombinant pure human Tim23 antigen was prepared, and injected into rabbits and polyclonal antibodies were raised, which was confirmed by western blotting. The transformed …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 32–44 Read article
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Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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Analysis of Hybrid Photovoltaic Thermal (PV/T) Integrated Solar Dryer: An Experimental Validation
Abstract: In this study, a hybrid photovoltaic thermal (PV/T) integrated solar dryer has been designed, developed, and experimentally analyzed to evaluate its performance in real-world climatic conditions. The system incorporates a UV-stabilized sheet mixed-mode tent house structure, installed on the rooftop of a building located in Bhilai, Chhattisgarh, India. The dryer is equipped with a thermal collector directly connected to the drying chamber to enhance heat transfer efficiency. Experiments were conducted …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 1–6 Read article
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Past Life Regression and Psychiatry: A Critical Analysis
Abstract: Past Life Regression (PLR) is a controversial therapeutic approach. It is done through hypnosis, which recovers memories of previous lives. Although PLR has gained some popularity in alternative medicine, it is heavily criticized in mainstream psychiatry. As the effects have not been empirically validated. This study provides a comprehensive exploration of Past Life Regression (PLR), offering insights into how it can be understood within the realm of psychiatry. It delves …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article
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Effect of Compressive Strength of Core and Precast Concrete on the Behavior of Column Retrofitted by Precast Segment and FRP Wrapping - A Finite Element Study
Abstract: In the present investigation the effect of compressive strength of core and precast concrete on the behavior of columns retrofitted by attaching precast segments and followed by FRP wrapping through Finite Element Analysis. A rectangular column converted into an elliptical column by attaching precast segment is modeled using ANSYS workbench, A Finite Element Analysis software. A Finite Element Model is developed, considering various structural parameters such as grades of core …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 302–310 Read article
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Scientific Appraisal of Unani Drugs Used in Neurological Disorders
Abstract: Background: Neurological disorders are prevalent and are increasing. The Unani system of medicine provides insights into the pathogenesis, prevention, and treatment of these diseases. Objective: This study explores the Unani perspective on neurological disorders, focusing on therapies and the pharmacodynamics of related medicines. Methods: A comprehensive review of Unani literature was conducted using digital and traditional sources. Unani texts, like “Al Qanoon Fil Tib” by Ibn Sina and “Al Jami …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 34–44 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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Novel Laplace-domain Approach to the Electromagnetic Transients in Compensated High Voltage Power Lines
Abstract: This paper addresses the simulation of the electromagnetic transients developed in high voltage power lines, which are initiated by lightning discharges. The analysis can handle both individual and simultaneous series inductive and shunt capacitive compensation types. The sizes and locations of the compensating elements are included in the analysis. The derived Laplace s-domain mathematical model applies the concept of the ABCD transmission constants representing equivalent two-port networks. Applying the relations …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 15–21 Read article
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A Study to Assess the Knowledge and Attitude on Artificial Intelligence in Health Care Among Nursing Students at a Selected Nursing College in Kuppam
Abstract: Background: Artificial Intelligence (AI) is rapidly gaining prominence in healthcare, holding the potential to revolutionize patient care and streamline administrative processes. However, the preparedness of future nursing professionals for this technological shift, particularly their knowledge and attitudes towards AI in healthcare, remains a critical yet under-investigated area. This study aimed to assess the knowledge and attitudes of nursing students towards AI in healthcare at a selected nursing college in Kuppam, …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 1, 2026 · pp. 17–23 Read article
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Investigating The Feasibility of Basalt Fiber as A Carbon Fiber Substitute in Composites for Automotive Applications
Abstract: The escalating carbon footprint, a consequence of dwindling natural resources and surging energy demand, necessitates immediate measures to mitigate environmental impact. This prompted the current study: to look at alternative manufacturing materials that could be utilized as a carbon-free substitute without compromising on mechanical properties. Basalt fiber was identified as a potential eco-friendly replacement to carbon fiber which has several advantages over carbon fiber and is entirely natural and biodegradable. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 275–285 Read article
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The Impact of Food Fortification on Health and Nutrition
Abstract: This comprehensive study explores the critical role that food fortification plays in enhancing nutritional outcomes and overall health. Through an extensive review of existing literature, this article explores the diverse ways in which fortifying foods with essential nutrients positively influences public health. This analysis encompasses the benefits of fortification by addressing micronutrient deficiencies, promoting overall well-being, and preventing various health conditions. Food fortification is a pivotal intervention in the realm …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Unani Medicine Uncovered: Core Concepts And Quality Evaluations
Abstract: Unani medicine, a traditional healing system primarily reliant on herbal remedies, finds its roots in the ancient wisdom of Greek philosopher Hippocrates (460–377 BC) and his associates. Its evolution and prominence, however, owe much to the support of Persian and Arab empires before making its way to the Indian subcontinent around the mid-14th century. Unani practitioners believe that each individual possesses a unique temperament shaped by the interplay of four …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 10–17 Read article