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833 articles for “Resistance”
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Antimicrobial Resistance: - A Growing Serious Threat for Global Public Health
Abstract: Antibiotics, among the most significant discoveries of the 20th century, have prevented infectious diseases from claiming millions of lives. However, their widespread use and misuse have created strong selection pressure, enabling microbes to develop antimicrobial resistance (AMR) to many drugs. Over time, AMR has spread primarily through human-to-human contact, both within healthcare settings and in the community. It is driven by a complex interplay of healthcare and agricultural factors, including …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Antimicrobial Resistance in Veterinary Medicine
Abstract: Antimicrobial resistance is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of antimicrobial resistance, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 11–15 Read article
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Drug Resistance – Challenges & Ayurveda Solutions – Review Study
Abstract: Antimicrobial resistance & anticancer medicine resistance has been the challenge to the medical fraternity. There are different theories postulated for developing medicine resistance, that has resulted in the debate regarding the efficacy of the medicine; there has been increasing concern as the time take for developing resistance is getting shorter and the time for development a molecule has remained constant or increasing. This resulted in medicinal resistance within few years …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 13–16 Read article
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Three Techniques for DC Thevenin Resistance Using Pspice Simulation
Abstract: A time-domain method for certain types of excitations is proposed to determine Thevenin equivalent circuit for a circuit with resistors and dependent/independent sources. SPICE/Pspice model descriptions for resistors at constant temperature and dependent source are used. Instead of making the energy sources zero (as in frequency domain) the sources in time domain are described using model description cards available for time-domain current/voltage sources at the same time evaluating circuit for …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Pathogens in Nosocomial Infections: Epidemiology, Resistance, and Control Measures
Abstract: Nosocomial infections, also known as healthcare-associated infections (HAIs), are a serious global health issue, leading to higher patient morbidity, prolonged hospital stays, and increased medical costs. Various pathogens—such as bacteria, viruses, fungi, and parasites—are responsible for these infections, especially in healthcare environments where they easily spread. They can be transmitted through direct contact with infected patients, contaminated medical equipment, or even airborne particles.Patients with weakened immune systems, those requiring prolonged …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
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Antibiotics in the Modern Era: Challenges, Misuse, and the Fight Against Resistance
Abstract: Overuse and inappropriate use of antibiotics in human medicine, agriculture, and environmental pollution. It is one of the biggest public health risks of the 21st century. The discovery of new antibiotics slowdown and the emergence of multidrug-resistant (MDR) microorganisms has highlighted the urgent need to Creative approaches to fighting opposition. This review explores the current challenges in antibiotic use, the factors driving resistance, and the strategies being implemented to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 57–70 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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Investigation and Optimization of Resistance Spot Welding Parameters for Stainless Steel
Abstract: The present work examines the significant impact of resistance spot welding (RSW) process parameters on the properties and efficacy of connections created in sheets of 316L stainless steel. This study examines the intricate relationship between welding parameters, investigating their influence on the microstructure, mechanical characteristics, and overall efficacy of welded connections. By employing a methodical experimental methodology, this study thoroughly investigates the impact of different factors in resistance spot welding …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 3, 2025 · pp. 15–21 Read article
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The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
Abstract: The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective. Parallel to the escalating resistance rates is a profound “discovery void,” characterised by a steep decline in the development of new antibiotic classes since the late 20th century. Together, these two interconnected crises create …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 47–65 Read article
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The Global and Regional Challenge of Pan-Antibiotic Resistance: A Review of Emerging Threats and Mechanisms
Abstract: Antimicrobial resistance (AMR) is one of the major and most intricate threats to the health of the 21st century as it is core to the undermined expertise of the common clinical practice and public health security worldwide. The problem is characterized by the extensive development of bacterial pathogens into extremely drug-resistant (XDR) and pan-drug-resistant (PDR) so- called superbugs faster than it can be done with therapeutics. It is a synthesis …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Isolation, Purification, and Identification of Antibiotic-Resistant Bacterial Strain from Food Stuffs
Abstract: The widespread presence of bacteria in foodstuffs poses significant trouble to health and food safety. Pathogens in consumable products increases the transmission of resistance genes to human, potentially compromising the efficacy of conventional antibiotics. This study aims to isolate, purify, and identify antibiotic-resistant bacterial strains from food items, meals, and vegetables. The investigation employed selective culture techniques, antibiotic susceptibility assays, and molecular identification methods to detect and characterize resistant strains. …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 37–45 Read article
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Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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Innovations in Tuberculosis Management: Advancements in Drug-Resistant TB Treatment and Rapid Diagnostics
Abstract: Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, exacerbated by the increasing prevalence of drug-resistant strains, such as multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB). Despite advancements in first-line and second-line treatments, resistance to conventional antibiotics has complicated therapeutic strategies, necessitating novel approaches. This mini review explores emerging advancements in TB treatment, including gene editing technologies, such as CRISPR, which offer potential for precise targeting of drug-resistant bacterial …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
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Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article