Search
146 articles for “Pharmaceutical research”
-
AI-based Drug Discovery-Revolutionizing Pharmaceutical Research
Abstract: The traditional drug discovery process is often costly, time-consuming, and prone to high failure rates. The advent of Artificial Intelligence (AI) has revolutionized this field by significantly enhancing efficiency, reducing costs, and improving success rates. AI-driven approaches, including machine learning (ML), deep learning (DL), and natural language processing (NLP), have transformed key areas such as drug target identification, molecular screening, lead optimization, and clinical trial design. AI models can analyze …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 30–44 Read article
-
Graphs and Their Real-Life Applications in Pharmaceutical Research
Abstract: This study provides a comprehensive overview of the role of graphs in pharmacy research, emphasizing their significance as powerful tools for data visualization, interpretation, and communication. In the field of pharmacy, research often generates large volumes of complex data related to drug development, pharmacokinetics, pharmacodynamics, medication safety, and patient outcomes. Graphs serve as an essential medium to translate these data into accessible, interpretable, and actionable insights, supporting evidence-based practice and …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 01–08 Read article
-
Application of Metabolomics in Pharmacognosy
Abstract: In the field of pharmacognosy, the identification, quality control, and bioactivity evaluation of medicinal plants and natural products have become significantly more effective thanks to the development of a strong tool known as metabolomics, which is the complete study of small-molecule metabolites in biological systems. Metabolomics offers more in-depth insights into phytochemical composition, plant metabolism, and the mechanisms that underlie medicinal benefits. It does this by enabling high-throughput analysis and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
-
Understanding Market Research and Marketing Intelligence in Pharmaceutical Marketing: Role played by Medical Affairs
Abstract: Market Research and Marketing Intelligence are crucial components in pharmaceutical marketing, providing insights that drive strategic decisions and competitive advantage. Market research in the pharmaceutical industry involves collecting and analyzing data to understand market demands, patient preferences, and the competitive landscape. Understanding market research and marketing intelligence in pharmaceutical marketing is very important and medical affairs play a key role by serving as a bridge between scientific knowledge and market …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 124–129 Read article
-
Use of AI Tools to Create New Drugs
Abstract: The emergence of artificial intelligence in pharmaceutical research [in drug discovery] is a revolution in pharmaceutical research, often combining computational methods with traditional research methods to solve problems. This review article describes various applications of artificial intelligence at various stages of drug development and highlights significant advances and approaches. He explores the critical role of intelligence in drug design, polypharmacology, drug synthesis, drug repurposing, and prediction of drug properties, such …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 22–49 Read article
-
A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
-
The Impact of Artificial Intelligence on the Sales and Marketing of Pharmaceutical Products
Abstract: The rapid development of computing and technology has permeated all branches of science, with artificial intelligence (AI) emerging as a pivotal field in computer science. AI has significantly influenced disciplines ranging from basic engineering to pharmaceuticals. In healthcare and medicinal chemistry, AI applications have become indispensable. Traditional drug discovery approaches are gradually being overtaken by computer-aided drug design. In recent years, artificial intelligence (AI) and machine learning (ML) have become …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 1, 2025 · pp. 10–18 Read article
-
InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
-
A Systematic Review of Impurity Profiling and Stability Studies in Pharmaceutical Drug Substances
Abstract: Ensuring the safety, efficacy, and quality of pharmaceutical goods is essential in the Indian pharmaceutical market, which is a global centre for generic drugs. Stability studies and impurity profiling are two fundamental activities that ensure this quality during the whole lifespan of a medicine. The effect of environmental variables such as temperature, humidity, and light on the quality of a drug substance over time is demonstrated by stability studies. The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 81–88 Read article
-
Regression Analysis of Topological Indices and Physicochemical Properties of Polymer-Based Anticancer Drugs
Abstract: The research analyzed the quantitative correlation between topological indices and the physicochemical properties of selected anticancer compounds using regression analysis. Various topological descriptors—such as the First Zagreb Index, Second Zagreb Index, and Forgotten Index were calculated and regressed against key molecular features, including polar surface area, melting point, and molar refractivity. The regression analysis revealed linear correlations between these topological indices and the properties of anticancer drugs, with particularly strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 255–267 Read article
-
Zebrafish in Drug Research: Decoding Biological Mechanisms and Finding Novel Therapeutic Targets
Abstract: The zebrafish, scientifically known as Danio rerio, is a powerful model organism in biological research because of its favorable traits, which include rapid development, genetic tractability, and transparent embryos. Zebrafish were first identified for their use in studies of vertebrate development, but they have since spread to a variety of disciplines, such as pharmacology, clinical research as a disease model, and most notably, drug development. Zebrafish have emerged as a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–8 Read article
-
pH-Triggered In-Situ Nasal Gel Systems for Migraine Therapy: A Review
Abstract: Intranasal drug delivery has gained considerable attention as a non-invasive route for delivering drugs to both systemic circulation and the central nervous system, particularly for the treatment of migraine. Traditional nasal formulations such as sprays and drops often show poor therapeutic performance due to rapid mucociliary clearance and limited retention within the nasal cavity. To overcome these challenges, in-situ gel systems have been designed, which transform from a liquid to …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
-
AI-Powered Drug Delivery: Revolutionizing Formulation Science
Abstract: Artificial Intelligence (AI) is emerging as a groundbreaking tool in revolutionizing Drug Delivery Systems (DDS), offering promising advancements in precision, efficiency, and personalized treatment strategies. The integration of AI technologies into pharmaceutical research and development is transforming how drugs are formulated, delivered, and monitored in real time. By leveraging machine learning algorithms and data analytics, researchers can design drug delivery models that are not only more effective but also tailored …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 48–61 Read article
-
Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
-
Advances in Solubility Enhancement Strategies for Poorly Water-soluble Drugs: A Comprehensive Review
Abstract: Solubility enhancement holds significant importance in the field of pharmaceutical research as it aims to augment the solubility and bioavailability of drugs that possess low solubility. Poorly soluble drugs pose a considerable challenge in drug development due to their tendency to display inadequate absorption, bioavailability, and therapeutic efficacy. The advancement of solubility enhancement techniques encompasses a wide range of approaches, including physical and chemical methods, as well as innovative technologies …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 01–09 Read article
-
AI Powered Invention in Pharmaceuticals Boosting Innovation
Abstract: Artificial intelligence has the potential to transform the drug discovery process, making the process more efficient, accurate and faster. But the success of artificial intelligence depends on the availability of good data, resolution of ethical issues, and awareness of the limitations of artificial intelligencebased methods. The present article examined the benefits, challenges, and shortcomings of skills in the workplace and suggested strategies and practical actions to overcome current challenges. Data …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 102–107 Read article
-
Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
-
Review on Bio and Chemical Reagents (Methods of Preparation and Uses)
Abstract: Among the organic compounds that are commonly used as chemical reagents in the field of pollution, removals of heavy metals from rivers, coordination chemistry and in various fields of life such as industry, medicine and pharmaceutical research are organic reagents such as oxime and imine azo reagents, Fehling’s and Tollen’s reagents and their derivatives. This type of reagent is characterized by high stability and rapid reaction with metal ions, as …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 2, 2025 · pp. 17–25 Read article
-
An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
-
Azepines, Chemistry, Synthesis and Reactions
Abstract: Azepines, which consist of a seven-membered cyclic compound featuring six carbon atoms, an additional nitrogen atom, and no double bonds between carbons, form a diverse group within organic chemistry. The fully hydrated form of this compound is called azepam (C6H13N). Compounds and their variants play crucial roles in pharmaceutical research due to their biologic attributes like cancer-fighting, bacteria-killing, fungus-busting, virus-suppressing, and inflammation-reducing capabilities. Various organic molecules found within nature draw …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 35–45 Read article