Search
38 articles for “substitution”
-
Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
-
Use of NMR and Other Spectroscopy Techniques in Heterocyclic Oxadiazole Derivatives Studies: A Review
Abstract: It was possible to create a number of novel symmetrical 2,5-dialkyl-1,3,4-oxadiazoles with substituents including carboxymethylamino, isopropyloxycarbonylmethylamino, and bromine at the terminal positions of the alkyl groups. The multistep process that was devised used hydrazine hydrate, phosphorus oxychloride, and commercially available acid chlorides that varied in alkyl chain length and terminal substituent.Diisopropyliminodiacetate was an easy way to substitute the intermediate bromine-containing 2,5-dialkyl-1,3,4-oxadiazoles. This was followed by hydrolysis in an aqueous methanol …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 07–13 Read article
-
Amlodipine induced peripheral edema and gingivitis – A case report.
Abstract: Calcium channel a group of drugs used to treat heart disorders are called blockers. These drugs dilate blood vessels and improve blood flow to heart, these works by preventing calcium flow through ion -specific (L- type) calcium channels in the cell membrane. Amlodipine, a calcium channel blocker in the dihydropyridine class, can cause peripheral edema and drug-induced gingivitis in some patients. In this case, the patient experienced swelling in the …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 45–49 Read article
-
A Dynamic Text Compression Model for Big Data Applications Using Hadoop
Abstract: In today’s data-driven era, efficiently handling vast amounts of information has become increasingly important. Data compression plays a vital role in this regard — it is essentially a method of encoding information in such a way that significantly reduces the number of bits required to store or transmit a file. By shrinking data to its most compact form, compression techniques help save storage space, reduce bandwidth consumption, and improve the …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 2, 2026 Read article
-
Comparison Study of Non-Alcoholic Sanitizer and Alcohol Based Sanitizer
Abstract: Hand sanitizer is the best choice to maintain the hand hygiene and stopping the spread of infectious diseases. The active ingredient in traditional hand sanitizers is usually alcohol, but worries about flammability, skin irritation, and possible abuse have prompted the creation and growing popularity of alcohol-free substitutes. The purpose of this review is to objectively assess the safety, effectiveness, and usefulness of alcohol-free hand sanitizers. To successfully eradicate germs, alcohol-free …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
-
Trichoderma: beneficial fungus for sustainable agriculture
Abstract: As environmentally beneficial substitutes for chemical pesticides, Trichoderma species are being utilized in agriculture more and more. Disease suppression, increased plant growth, and increased tolerance to environmental stress are just a few advantages they provide. These fungi are used in a wide range of cropping systems and formulations around the world. Their use is growing worldwide, particularly in Asia and Europe. In contemporary crop management, items derived from Trichoderma are …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 25–29 Read article
-
Grid based docking study of some 2-(4-methylsulfonyl phenyl) pyrimidine derivatives (designed after QSAR studies) with Cyclooxygenase
Abstract: Molecular docking helps in studying drug/ligand or receptor/ protein interactions by identifying the suitable active sites in protein, obtaining the best geometry of ligand-receptor complex and calculating the energy of interaction for different ligands to design more effective ligands. In Grid based docking, after unique conformers of the ligand are generated, the receptor cavity of interest is chosen and a grid is generated around the cavity. Cavity points are found …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 23–41 Read article
-
A Sociolinguistic Perspective on Hausa Loanwords in the Kəlba Language
Abstract: Linguistic borrowing is seen as a significant source of language development and enrichment. This study examines Hausa loanwords borrowed into the Chadic language of Kəlba, which is spoken in Gombi, Hong, Maiha, Mubi North, and Mubi South local government areas of Adamawa State, Nigeria. The lingua franca in most of northern Nigeria is Hausa, one of the indigenous national languages of the region. The primary sources of data for the …
Published in Emerging Trends in Languages · Vol. 2, Issue 1, 2025 · pp. 27–32 Read article
-
AI-Based Intelligent Traffic Signal Management System: A Review
Abstract: Traffic congestion is a growing problem in urban areas worldwide, leading to economic losses, increased pollution, and commuter frustration. Traditional traffic management systems rely on fixed timing cycles and lack adaptability to real-time traffic conditions. Intelligent traffic light control systems based on artificial intelligence (AI) have become a viable substitute for traditional techniques. These systems are able to evaluate large volumes of traffic data in real time, identify patterns, and …
Published in International Journal of Electronics Automation · Vol. 3, Issue 2, 2025 · pp. 1–5 Read article
-
Sensory Psychology of Supergrain Bakery: Consumer Perception Beyond Taste
Abstract: Bakery products remain a cornerstone of diets worldwide, yet wheat-based formulations are increasingly supplemented or replaced as consumers demand healthier, more functional alternatives. Supergrains such as quinoa, amaranth, millet, and cowpea, together with fruit-based flours such as guava flour, have been extensively investigated to enrich wheat-based products and improve their nutritional value. At the same time, the science of sensory psychology has become central to product acceptance, as taste, aroma, …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
-
Floating Cities from Concept to Creation :Neighbourhood Guide to the Future Development
Abstract: Today cities are overpopulated and only 40% of space is left to house the world's population by 2050. Due to ever rising sea level 90% of coastal cities will be affected by flooding by the end of the century. This research aims to study about the floating city as a substitute. Floating cities shape to construct all of the infrastructure required for a water-based metropolis while also providing contextual space …
Published in International Journal of Urban Design and Development Read article
-
Design and Fabrication of Automatic Timetable Generator and its Application
Abstract: Making a schedule manually is exceedingly challenging in today's literate environment. Timetables must be made specifically for each branch and each year. It becomes quite chaotic, time-consuming, and labor-intensive to manually prepare the timetables. When a staff member needs to be substituted or is on leave, the process can occasionally become complicated. In our effort, we have developed a timetable-creation algorithm that will save a lot of time while lessen …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 1, 2023 · pp. 21–25 Read article
-
Design and Development of Additive Manufacturing Machine
Abstract: Rapid prototyping, commonly referred to as 3D printing or additive manufacturing (AM), is the process of creating three-dimensional objects by layer-by-layer addition of material. It is very different from subtractive and conventional forming techniques. The goal of this special issue is to gather research and advancements in additive manufacturing (AM), with an emphasis on novel manufacturing techniques and substitute products and materials for feedstock. Although metal and polymer-based materials have …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
-
Bioethanol and Beyond: A Comprehensive Review on Sustainable Biofuels for Global Energy Demands and Environmental Conservation
Abstract: This comprehensive review explores the concept of "biofuels," specifically focusing on energy-enriched chemicals generated through biological processes or derived from the biomass of living organisms, including microalgae, plants, and bacteria. As the global population continues to increase, there is a growing demand for more energy supplies to enhance the quality of life. Biofuels, harnessed from various sources such as sugar, starch, and organic waste, have emerged as potential solutions to …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 1–9 Read article
-
Advancements in Energy-Efficient Electrical Motor Design: A Comprehensive Review
Abstract: The rapid growth in energy demand poses a fundamental challenge for the whole power industry in fulfilling the increased demand. An exhaustive energy audit recommends substituting energy-efficient gadgets with conventional ones, which function with low efficiency and waste a significant amount of electricity. Electric motors are quite common in contemporary life, providing energy to a wide range of devices, including both domestic and industrial machinery. Nevertheless, they bear the responsibility …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 1, 2023 · pp. 29–35 Read article
-
Exploring Decarbonization Strategies and Sustainable Alternatives for Cement
Abstract: As one of the most evolving economic sectors, building construction creates wealth and income while making a significant contribution to global development. Almost 40% of all carbon emissions, both direct and indirect, come from this industry. It is crucial to lower emissions from the manufacture of cement to mitigate climate change. The cement industry must be made less carbon-based. The need to address the environmental effects of traditional cement production, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
-
Harnessing the Medicinal Potential of SwertiaChirata: A Phytochemical Strategy for Controlling Coronavirus Symptoms Like High Fever and Anxiety
Abstract: The current investigation focuses on exploring the therapeutic capacities of SwertiaChirata, colloquially known as Chirata, in managing the symptomatic displays of coronavirus infections. Chirata, a member of the Gentianaceae family, is a distinguished herb extensively used in Ayurvedic and Unani medicinal traditions, acknowledged for its myriad of healing qualities. In addition to its regular use in combating fever and loss of appetite, its prominent antioxidant traits position it as an …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 27–31 Read article
-
Transportation Applications of Solar Energy: Innovations and Consequences
Abstract: The transportation industry is at the forefront of sustainability issues due to its substantial reliance on fossil fuels, which raises air pollution and greenhouse gas emissions. As a result, engineers and researchers have discovered that solar energy is a practical substitute for powering a variety of transportation vehicles. This study looks at the state of solar energy applications in the transportation industry today, exploring cutting-edge technologies, practical implementation issues, and …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 2, 2023 · pp. 39–44 Read article
-
Crystal Engineering Strategies for Tailoring Mechanical Properties of Structural Materials
Abstract: Crystal engineering has emerged as a promising approach for designing materials with tailored mechanical properties, enabling advancements in various fields such as aerospace, automotive, and construction. This review examines the diverse strategies employed in crystal engineering to manipulate the mechanical behavior of structural materials. One key strategy involves controlling the crystal structure at the atomic level through techniques such as alloying, doping, and phase transformations. Alloying introduces foreign atoms into …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 01–06 Read article
-
Gypsum Addition in Moulding Sand to Manufacture Defect Free Tin Castings
Abstract: Sand molding is a versatile casting process that provides freedom of design with respect to size, shape, and product quality. Plaster casting is similar to sand molding process except that a plaster is substituted instead of sand. Plaster compound is composed of gypsum, which strengthens the mould. Parts made by this process are gears, valves, fittings, tooling, and ornaments. The finished product of plaster casting has a very high surface …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 2, 2023 · pp. 7–15 Read article