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24 articles for “remodeling”
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Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
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Bone in Periodontal Health and Diseases: A Scoping Review
Abstract: Bone resorption is a basic physiologic process and central to the understanding of many key pathologies. Alveolar bone destruction is a hallmark of periodontal disease progression and its prevention is a key clinical challenge in treatment of periodontal disease. Bone loss is mediated by the host immune and inflammatory response to the microbial challenge. As individuals are not equally susceptible to the destructive effects of periodontal infections therefore, it is …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 1, 2021 · pp. 1–12 Read article
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Concept of Wound w.s.r. to Wound Healing
Abstract: Wound healing is an important but complicated process in humans. It consists of a multifaceted process governed by sequential yet overlapping phases including hemostasis/inflammation phase, proliferation phase and remodeling phase. Much effort has been focused on wound care with an emphasis on new therapeutic approaches and the development of technologies for wound management. Wound healing is a continuous process and divided into four phases. Regeneration and tissue repair processes consist …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 2, 2021 · pp. 36–43 Read article
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The Induction, Formation, and Establishment of Giant Cell in Plant-Parasitic (Meloidogyne Spp.)-Host Interactions: A Molecular and Cellular Basis
Abstract: Root-knot nematodes, (RKN) are obligatory endoparasites of over 3000 plant species, causing $70 billion in annual economic losses globally. The second stage juveniles hatch from the eggs invade the root apex and inject pathogen effectors that induce specialized feeding cell called Giants cell that are large multinucleated cell formed, due to repeated cycles of mitosis without cytokinesis and served sole source of feeding site for rootknot nematode. The ability RNN …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 34–45 Read article
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Socket Preservation: Review
Abstract: The removal of a tooth results in remodeling and absorption not only within the socket but also in the surrounding alveolar bone. Alterations in the bone ridge following extraction are unavoidable, influenced by the initial size of the socket, with wider sockets requiring more time to heal completely. Both the height and width of the bone undergo dimensional changes subsequent to tooth extraction.The volumetric bone reduction changes occur after tooth …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 8–13 Read article
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Integrative Network Biology Analysis of GSE6011 Uncovers Molecular Signatures in Duchenne Muscular Dystrophy
Abstract: Duchenne muscular dystrophy (DMD) is a rare, severe neuromuscular disorder demonstrated by progressive skeletal muscle deterioration and premature mortality. Despite advances in supportive care, no definitive cure exists, highlighting the need to explore novel molecular targets. The current study aimed to uncover key dysregulated genes and molecular pathways in DMD through a dataset-specific network biology approach. Publicly available microarray data (GSE6011) from DMD quadriceps muscle biopsies of 22 patients and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 36–48 Read article
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Impact of Hypoxia on Cardiopulmonary Adaptation in Canines: A Comprehensive Review
Abstract: Hypoxia triggers a series of cardiopulmonary responses that play an important role in oxygen delivery and the continuation of physiological activity in mammals. Canines are also a useful translational model of study to examine these adaptive responses because of their anatomical, physiological, and cardiopulmonary differences with humans. This review summarizes the experimental data of acute, subacute and chronic hypoxia in dogs with particular focus on the variations in cardiac functioning, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 13–24 Read article
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Differential Gene Expression Analysis of Human Atrial Fibroblasts Reveals Dysregulation of RNA Metabolism and Translational Machinery in Atrial Fibrillation
Abstract: Atrial fibrillation (AF) is a complex cardiac arrhythmia characterized by extensive structural remodeling and the activation of atrial fibroblasts, which drive the progression of fibrosis. To identify the underlying transcriptomic alterations, we analyzed six human atrial fibroblast RNA-Seq datasets (three control and three AF) retrieved from the Sequence Read Archive. After performing rigorous quality control and adapter trimming, we aligned the reads to the GRCh38 human reference genome using a …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 · pp. 15–25 Read article
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REPEATED MOPs VS DUAL APPROACH IN ACCELERATED ORTHODONTICS
Abstract: In contemporary orthodontics, there is a pressing need to minimize treatment duration, which is often a concern for both orthodontic specialists and patients. Prolonged treatment periods not only pose logistical challenges but also increase the risks of various dental issues such as cavities, periodontal problems, chronic discomfort, and root resorption. Accelerated orthodontics has emerged as a promising solution to address these challenges. Numerous efforts have been undertaken to expedite orthodontic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 16–21 Read article
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Advanced Techniques in Filler Layering for the Malar Region: Implications for Cellular Integrity and Long-Term Outcomes
Abstract: Objective: This review investigates advanced filler layering techniques for the malar region, focusing on cellular integration, collagen remodeling, hydration dynamics via aquaporin channels, genetic responses, and filler performance over time. Emphasis is placed on high-density HA fillers (Lyft, Voluma, Volift, and Volux), examining cellular-level mechanisms, genetic interactions, and the role of key pathways (TGF-β, ERK/MAPK, AQP3) in long-term outcomes. Methods: A systematic review was conducted, focusing on genetic, cellular, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 10–19 Read article
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Long Non-Coding RNAs: Key Regulators of Gene Expression in Development and Disease
Abstract: Long non-coding RNAs (lncRNAs) are RNA molecules that do not make proteins but are essential for controlling how genes are turned on or off in the body. These molecules help with various biological functions, such as guiding cell growth, shaping development, and influencing the progression of diseases. Recent advancements in genomics and transcriptomics have revealed the vast and complex roles of lncRNAs, with an increasing recognition of their involvement in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 11–15 Read article
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Judicial Oversight of Biometric Evidence and The Role of Polymer and Composite Technologies in Indian Criminal Trials
Abstract: This paper critically looks at changes that have taken place in the role of forensic science in the remodeled Indian criminal justice system and how the modern law has deviated since the colonial laws. With the changing of reformatory model of justice to a more balanced one that suggests fairness and due process, the study lends weight to the increasing cases of clarity, consistency and control in the field of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 141–152 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Identification of Hub Genes and Enriched Gene Ontology & Pathways in Idiopathic Pulmonary Fibrosis Through Bioinformatics Approaches
Abstract: Idiopathic Pulmonary Fibrosis (IPF) is a progressive interstitial lung disease marked by aberrant remodeling of lung tissue and excessive extracellular matrix deposition, ultimately leading to respiratory failure. Despite ongoing research, the molecular mechanisms underlying IPF remain incompletely understood. This research aims to uncover differentially expressed genes (DEGs) and related biological pathways through an integrated analysis of microarray data. Two publicly available datasets, GSE110147 and GSE53845, were obtained from the Gene …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 1–13 Read article
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Recent Advancements in Nanobiocomposite-Based Wound Healing and Tissue Regeneration
Abstract: Haemostasis, inflammation, proliferation, remodeling, and other highly coordinated cellular and molecular activities are all part of the complex biological processes of wound healing and tissue regeneration. Following an injury, these stages cooperate to restore tissue integrity and function. However, this normal process is disturbed in many clinical circumstances, especially chronic wounds such diabetic ulcers, burns, and pressure sores. Prolonged inflammation, chronic microbial infection, diminished angiogenesis, and impaired extracellular matrix production …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–318 Read article
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Design and Fabrication of Hybrid Two-Wheeler
Abstract: Hybrid-electric vehicle (HEV) combines the benefits of petrol engines and electric motors and can be configured to obtain different objectives, such as improved fuel economy, increased power and reduced emission leads to green environment. In recent days, availability of fuel source is depleting day by day and due to more consumption of fuel, the environmental pollution is increasing. In order to overcome that issue we have remodelled a two wheeler …
Published in Journal of Automobile Engineering and Applications · Vol. 4, Issue 3, 2017 · pp. 1–5 Read article
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Fabrication of Delta-Frame 3D Printer to Reduce Print Time
Abstract: 3D printing refers to a process of printing 3-dimensional objects, also known as “rapid prototyping”. The reason behind the wide use of a 3D printer is that it enables the creators to deliver a model of what they want in a short period of time, which is tested and quickly remodelled if needed. This significantly decreases the expected time to get from the model stage to the final product. At …
Published in Journal of Control & Instrumentation · Vol. 9, Issue 2, 2018 · pp. 12–16 Read article
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Simulation of Three Section Multilevel Inverter with Reduced Range of Switches
Abstract: Because of high generation development, the demand and excellent of electric strength ishigher than earlier than. Furthermore, due to the advancement of semiconductor, thespecification of electricity devices and strength conversion method turn out to be stricter. Oneof the energy converters that may remodel DC to AC is called inverter. An inverter is the intermedium to transmit the electricity to other electric device such as an uninterruptibleelectricity supply, servo motor, air-conditioner …
Published in Journal of VLSI Design Tools and Technology · Vol. 10, Issue 1, 2020 · pp. 15–36 Read article