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58 articles for “progressive failure”
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Progressive Collapse Prevention Analysis of Multi-Storeyed Buildings by Using Pushover Analysis
Abstract: AbstractThis paper investigates an actual structure’s potential to break due to progressive collapse. This report looks into the progressive collapse resistance of high-rise RC structures. Progressive collapse of building constructions, primarily concentrates on concrete structures. Progressive collapse of a structure occurs when major structural load carrying members are removed suddenly. A progressive collapse is initiated as a consequence of local structural damages. It produces a chain reaction mechanism, into a …
Published in Journal of Structural Engineering and Management · Vol. 4, Issue 3, 2017 · pp. 17–23 Read article
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A Shear Strength Reduction Method for an Open Pit Slope Stability Analysis Based on Finite Element Method
Abstract: Slope stability assessment of open pit mines is critically important, since it forms part of the overall productivity and safety management strategy of the mines. The aim of this work is to investigate the overall stability conditions of three (3) open pits in Gold Fields Limited, Tarkwa Ghana. Field and laboratory investigations were conducted as well as empirical methods. Finite Element Analysis (FEA) in Rocscience was carried out using the …
Published in Journal of Geotechnical Engineering · Vol. 13, Issue 1, 2026 · pp. 1–24 Read article
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Geotechnical study of a landslide reactivation in clay soils (central Piedmont, NW Italy).
Abstract: In March 2015, exceptional meteoric events occurred in southern Piedmont caused a remarkable rise of the rivers water level of the Tanaro Basin with flooding and many landslides. The engineering geological study reported here, concerns a triggering of a previous landslide occurred in 1982 in the hills, shaped in the marine sedimentary succession (Lugagnano Clay, lower Pliocene) of the southern Asti Reliefs, near San Martino Alfieri village. Detailed geological, morphological …
Published in Journal of Geotechnical Engineering · Vol. 7, Issue 1, 2020 · pp. 21–36 Read article
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Numerical Investigation of Ply-by-Ply Failure and Strength Degradation in Composite Laminates Under Transverse Loading
Abstract: This paper represents the failure analysis of composite symmetric and antisymmetric laminate, when laminates were subjected to the transverse loading conditions. The load is uniformly distributed in a transverse direction. The analysis includes failure load and nature of failure by using theories of failure. The ply degradation material model is used to modify and update the properties of failed lamina and upgrades the properties of laminate. Laminate is modelled as …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Experimental and Numerical Investigation of Corrosion-Induced Failures in Copper-Tin Alloy (Cu-Sn) and Aluminum-Magnesium Alloy (Al-Mg) Connectors: A Stress–Corrosion Coupling Analysis
Abstract: The utilization of an integrated experimental and finite element modelling (FEM) methodology, this study investigates the degradation and failure mechanisms in polymer composite electrical connectors exposed to aggressive environmental conditions. Epoxy- and polyamide-based composites, reinforced with carbon and glass fibers, were subjected to accelerated salt spray and humidity–temperature cycles to simulate prolonged outdoor exposure. Electrochemical and environmental aging experiments revealed that chloride ions and moisture ingress were responsible for matrix …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 366–379 Read article
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An Overview of Fanconi Anemia: A Genetic Disorder
Abstract: Fanconi Anemia (FA) is a rare genetic disorder caused by DNA repair defects due to pathogenic variants in one of 21 genes. It is the primary cause of inherited bone marrow failure, marked by pancytopenia. Clinically, Fanconi Anemia (FA) is associated with congenital malformations in multiple systems, resulting in progressive bone marrow failure and heightened cancer risk, especially in the urogenital region and the head and neck. There are approximately …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 19–25 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
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Effect of Viscoelastic Dampers on Progressive Collapse Resistance of RC Building
Abstract: Natural as well as man-made hazards may cause the failure of the primary load bearing members of buildings. The spread of an initial local failure from element to element, eventually result into the collapse of an entire structure or a large part of it, which is known as Progressive Collapse. Progressive collapse initiates when one or more primary load bearing elements get fails causing failure of the entire structure. It …
Published in Journal of Structural Engineering and Management · Vol. 4, Issue 1, 2017 · pp. 27–34 Read article
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Effect of Outriggers Location on Performance of RC Building Subjected to Loss of a Column
Abstract: Progressive collapse denotes a failure of substantial part of the structure, causing greater damage to the structure than the initial impact, which has been initiated by failure of a relatively small part of the structure such as failure of any vertical load carrying elements (typically columns). Failure of large part of any structure will result into substantial loss of human lives and natural resources. Therefore, it is important to prevent …
Published in Journal of Structural Engineering and Management · Vol. 4, Issue 1, 2017 · pp. 65–72 Read article
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Progressive collapse analysis study of rc building:a review
Abstract: The progressive collapse of building is that the collapse of whole building or a part of building in progressive manner thanks to spread of local failure from element to element. thanks to progressive collapse there'll be severe loss of building and lifetime of humanity as progressive collapse happens suddenly. Toavoid the loss got to design a building by proper study and analysis of building for progressive collapse. thanks to earthquake, …
Published in Recent Trends in Civil Engineering & Technology · Vol. 11, Issue 2, 2021 · pp. 13–19 Read article
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Material-Level Degradation of Magnetorheological Fluids Under Long-Term Cyclic Shear
Abstract: The long-term functional stability of magnetorheological fluids (MRF) remains a key limitation for their reliable use in adaptive systems and continuously operated magnetorheological devices. In this study, the intrinsic evolution of rheological properties in a commercial MRF (MRC-C1L) is systematically examined under prolonged cyclic loading, with the aim of isolating material-level degradation mechanisms independent of device-related effects. The fluid was subjected to 120,000 low-strain oscillatory shear cycles under a constant …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 101–112 Read article
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AI-Driven Topology Optimization of Woven Fiber-Reinforced Composite Chassis Structures for Electric Vehicles Under Crash Loading
Abstract: The structural design of an electric vehicle (EV) chassis represents a unique engineering challenge to achieve minimal weight while meeting occupants' safety requirements during high-energy crash conditions without compromise to the battery housing's integrity or the geometrical constraints of the electric powertrain package. In this paper, a single framework is proposed to integrate physics-based artificial intelligence (AI) surrogate models using PINNs, CNN-accelerated topology optimization, and FEA to design woven fiber-reinforced …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 72–89 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Role of Fatigue and Creep in Structural Damage: A Comprehensive Review
Abstract: Fatigue and creep are two critical degradation mechanisms that significantly influence the structural integrity and longevity of engineering materials. These phenomena arise due to different loading and environmental conditions but often coexist in various industrial applications, leading to severe material degradation over time. Fatigue primarily results from cyclic loading, where repeated stress variations induce microstructural damage and crack initiation, ultimately causing catastrophic failure. Conversely, creep occurs under sustained stress at …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 1, 2025 · pp. 22–26 Read article
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Analysis and A.I. Modelling of Parameters of Symmetrical Multistory Building using Non-linear Static Analysis
Abstract: Non-linear static analysis (Push over Analysis) is the emerging field in seismic design of structures.The major drawback of elastic analysis is that the response beyond the linear state is neither linearnor simple extrapolation. Although elastic analysis gives a good indication of the elastic capacity ofstructures, but it cannot account for redistribution of forces during progressive yielding of a structurethat follows and to predict its failure mechanism or detect possible location …
Published in Journal of Construction Engineering, Technology & Management · Vol. 11, Issue 1, 2021 · pp. 1–15 Read article
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Chronic Renal Failure: A General Review
Abstract: Chronic renal failure is also known as chronic kidney disease in which there is progressive loss in kidney function over a period of months or years. The symptoms of worsening kidney function are not specific and might include feeling generally unwell and experiencing a reduced appetite. The definition of chronic kidney disease has been simplified over the last 5 years. It is now defined as the presence of kidney damage …
Published in Research and Reviews : Journal of Surgery · Vol. 10, Issue 3, 2021 · pp. 23–31 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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Hybrid Machine Learning and Finite Element Framework for Predicting Damage Behavior in Fiber-Reinforced Polymer Composites
Abstract: Fiber Reinforced Polymer (FRP) composites have broad spread use in aerospace, automotive, marine and structural applications due to its high specific strength, stiffness and corrosion resistance. The various damage mechanisms such as matrix cracking, fiber breakage, delamination and interfacial failure, however, make the forecasting of damage particularly complex. In this work, a hybrid machine learning (ML) and finite element (FE) system is proposed for predicting the damage behavior of FRP …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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From Concept to Clinical Practice: A Detailed Review of Total Artificial Heart Devices
Abstract: Total artificial heart (TAH) devices are mechanical systems designed to take over the role of a failing heart in patients with severe heart failure. Unlike ventricular assistance devices (VADs), which only support one side of the heart, TAHs replace both ventricles, providing a possible solution for patients who cannot receive a heart transplant. Over time, TAH technology has evolved with a focus on improving biocompatibility, reducing complications related to the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 1–4 Read article