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10 articles for “heart failure treatment”
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Tools, Modern Drugs, and Latest Investigations for the Diagnosis and Treatment of Heart Failure: A Systematic Review of the General Causes
Abstract: Heart failure (HF) diagnosis and treatment present formidable challenges, given the absence of a definitive single test. This systematic literature review aims to comprehensively analyze the current landscape of diagnostic tools, modern drugs, and latest investigative approaches in HF management. Recognizing the complexity of HF etiology, this systematic review emphasizes the importance of advanced diagnostic methods, such as genetic testing and artificial intelligence applications. The systematic review was conducted to …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–10 Read article
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From Concept to Clinical Practice: A Detailed Review of Total Artificial Heart Devices
Abstract: Total artificial heart (TAH) devices are mechanical systems designed to take over the role of a failing heart in patients with severe heart failure. Unlike ventricular assistance devices (VADs), which only support one side of the heart, TAHs replace both ventricles, providing a possible solution for patients who cannot receive a heart transplant. Over time, TAH technology has evolved with a focus on improving biocompatibility, reducing complications related to the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 1–4 Read article
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Thalassemia and its management – A review article
Abstract: Thalassemia is a hemoglobinopathy burdening India making it earn title of Thalassemia capital of world. Studying last decade, the overall prevalence worldwide and incidence rates have declined but prevalence rates were high in east and Southeast Asian countries. Screening for carriers and affected individuals and genetic counselling are promising approaches for reducing soaring cases and reducing the further spread. Thalassemia affects various organs due to iron overload and haemolysis leading …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 60–73 Read article
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Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
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The Evaluation of the Light Parameters and Pleural Fluid Cholesterol to Determine the Differences Between Exudative and Transudative Pleural Discharge
Abstract: Background: Pleural effusion occurs when an imbalance between pleural fluid production and absorption leads to the accumulation of excess fluid in the pleural cavity. Pleural effusions are commonly classified into two types: transudative or exudative, depending on the underlying mechanism of fluid formation. While transudates typically result from systemic factors like heart failure or liver cirrhosis, exudates are usually caused by local factors such as infection, malignancy, or inflammation. Differentiating …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 30–35 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article