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73 articles for “genetic variation”
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Evaluation of Genetic Variation in Endangered Tree Species of Boswellia serrata with the Help of Genetic Markers
Abstract: Salai (Boswellia serrata) is the most valuable medicinal tree. It has many medicinal properties like anti-inflammatory agent extensively used in ayurvedic formulations for relieving ache and pain, particularly associated with arthritis. In this study, identification of potential pockets of the designated species in different agro-climatic zones of Madhya Pradesh and evaluation of genetic variation with help of RAPD markers of Boswellia serrata is done, so as to produce elite genotype …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 1, 2017 · pp. 22–26 Read article
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Analysis of Genetic Variation in Celastrus paniculatus Willd. among Different Populations of Southern Western Ghats
Abstract: AbstractCelastrus paniculatus Willd. is an important threatened medicinal woody liana native to the Indian subcontinent. It is distributed chiefly in the deciduous forests, up to an altitude of 1800 m. This species is globally distributed from South Asia to Australia. The seed oil of C. paniculatus is used as a brain tonic for enhancing memory. Due to the over exploitation of the plant for its medicinal values, the plant is …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 63–70 Read article
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Significance of TE Domain and Genetic Variations in FASN Gene in Dairy Animals
Abstract: The interest in the bovine fatty acid synthase (FASN) gene has increased during the last few years. FASN is a multifunctional enzyme that catalyzes de novo biosynthesis of long-chain saturated fatty acid, and alteration of this enzyme may affect economic traits including fatty acid composition. FASN is involved in fat metabolism and is an important candidate gene affecting fat composition of milk because of its central role in de-novo lipogenesis …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 33–38 Read article
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Molecular Diversity of Lampito mauritii and Perionyx excavatus Across North Eastern Ghats of Odisha Using RAPD Markers
Abstract: RAPD-PCR technique using 15 RAPD random primers was used to analyze genetic variation of Lampito mauritti and Perionyx excavatus adult worms collected from the agroclimatic zone of North Eastern Ghats of Odisha which includes four different districts. Studies on molecular characterization of L. mauritti and P. excavatus from different geographical locations indicated variation in the molecular profiling. Analysis of genetic diversity was performed using DNA marker systems with RAPD to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 2, 2018 · pp. 33–41 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Pharmacogenomics and Precision Medicine an Evolving Analytical Clinical Tools for Future Medicine – A Narrative Review
Abstract: The term Pharmacogenomics is coined as an emerging field that exactly examines how the genetic variations influence the individual responses towards medications. This discipline in turn integrates the pharmacology as well as genomics to facilitate the personalized medicine, encouraging the healthcare providers to tailor their drug therapies based on individual patient’s genetic profile. Key applications include optimizing drug efficacy, minimizing adverse effects, and enhancing treatment outcomes across various medical fields, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 44–52 Read article
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Morphological and Biomass Performance of Indigenous Agroforestry Tree Species Seedlings under Different Provenances at Nursery Level, in Central Ethiopia
Abstract: Multipurpose trees are significantly important for climate change resistance in such a way that they contribute to both climate change adaptation and mitigation. In addition, they have important economic and social benefits for the livelihoods of farmers and also have a considerable effect on the GDP of the country. Therefore, to improve species’ adaptation in specific, site genetics fitness is an important factor. Therefore, the objective of the research was …
Published in Research & Reviews : Journal of Botany · Vol. 11, Issue 3, 2022 · pp. 47–58 Read article
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Analysis of Genetic Basis for Morphological Variations in Normal and Tissue Cultured Plants of Andrographis paniculata in Association with or Without Arbuscular Mycorrhizal Fungi using AFLP Markers
Abstract: Andrographis paniculata Nees, a member of Acanthaceae, is one of the important medicinal herbs. The active principle, Andrographolide esters has a paramount importance in pharmaceutics. Morphological variants have been reported both in natural populations collected from various geographical areas and micropropagated plants raised through tissue culture that need to be analyzed with proper molecular tools. In order to facilitate reasoned scientific decisions on its management, conservation and prepare for a …
Published in Research & Reviews : Journal of Botany · Vol. 8, Issue 1, 2019 · pp. 1–11 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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From Ancient DNA to Modern Livestock: Paleogenomics
Abstract: Paleogenomics, an interdisciplinary blend of paleontology and genomics, has revolutionized our understanding of ancient DNA and its applications across various fields. In Animal Genetics and Breeding, this field has emerged as a pivotal tool providing invaluable insights into the historical genetics of domesticated animals. By reconstructing and analyzing the genomes of long-extinct organisms, paleogenomics sheds light on genetic diversity, evolutionary dynamics, and adaptations of ancient species. Paleogenomics significantly impacts animal …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 1–6 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 · pp. 33–40 Read article
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A Review on Advances in Personalized Medicine: from Genomics to Clinical Applications
Abstract: Personalised medicine, also known as precision medicine, is a revolutionary approach to healthcare that customises medical interventions and treatments for individual patients according to their distinct genetic, environmental, and lifestyle properties. The basic pillar of personalised medicine is genomics, and the area has seen an explosion of genetic information with the advent of high-throughput sequencing tools. Genomic data now provide unprecedented insights into the underlying genetic variations, mutations, and genetic …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 13–17 Read article
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Plant Evolutionary Biology: An Insight into Adaptations and Diversity
Abstract: The study of plant evolutionary biology provides crucial insights into the remarkable diversity and adaptation of plants. This review work aims to explore the fascinating world of plant evolution, discussing key concepts, patterns, and mechanisms that have shaped the plant kingdom over millions of years. The review begins by highlighting the immense diversity of plant species, categorizing them into major groups and elucidating their distinctive characteristics. It further examines the …
Published in Research & Reviews : Journal of Botany · Vol. 12, Issue 1, 2023 · pp. 18–23 Read article
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Phenetic Analysis of Solanum melongena Accessions to Explore the Genetic Diversity by SDS-PAGE
Abstract: The present experimental work was conducted for the phenetic analysis among 40 accessions of Solanum melongena from different geographical areas of Pakistan. The interspecific variation was found among the accessions of S. melongena. The analysis of seed storage was done by SDS-PAGE to check their relationship. Electrophoretic data was documented by gel documentation system (Bio-Rad, USA), and analyzed by using quantity 1-D analysis software and dendogram constructed with 100% tolerance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 2, Issue 2, 2012 · pp. 21–34 Read article
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Diet-Gene Interactions in Farm Animals: Molecular Dynamics, Gene Expressions, Signalling Pathways and Precision Nutrition for Sustainable Productivity
Abstract: Diet-gene interactions represent a central mechanism through which nutrition influences growth, health, and productivity in farm animals. Recent advances in molecular biology and genetics have revealed that nutrients act not only as metabolic substrates but also as signalling molecules capable of modulating gene expression, cellular pathways, and epigenetic regulation. This review synthesizes current knowledge on the molecular dynamics of nutrient utilization in farm animals, with emphasis on nutrigenomic responses, nutrient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 · pp. 69–76 Read article
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ISSR Marker Analysis of Cypriniform Fishes in Southern Western Ghats
Abstract: The conservation biology and knowledge of the relatedness between populations is particularly important in absorbed breeding programs that attempt to reduce incestuous mating in order to minimize inbreeding. A decline in genetic variation reduces the ability of a population to adapt to environmental changes and decreases its long term survival. The molecular genetic variability among three cyprinids fish species (D. aequippinatus, G. mullya and D. filamentosa) using ISSR markers was …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 3, 2019 · pp. 26–29 Read article
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Study of DFIG with Rotor Excited Through Inverter and Method of Efficiency Maximization
Abstract: AbstractIn order to extract maximum power output from a DFIG or Doubly fed Induction Generator, maximum mechanical power must be extracted from wind turbine and the losses must be minimized. As the wind speed is not fixed, in order to get maximum power and minimum losses, the d-axis and q-axis rotor currents I*dr and I*qr are controlled according to the changes in wind speed. In this research, Genetic Algorithms are …
Published in Research & Reviews : Journal of Physics · Vol. 9, Issue 1, 2020 · pp. 51–56 Read article
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Bioinformatics in Veterinary Science: Unraveling Disease Patterns and Genomic Insights.
Abstract: Bioinformatics has emerged as a powerful tool in veterinary science, enabling the unraveling of disease patterns and providing valuable genomic insights. This article explores the application of bioinformatics in veterinary research, focusing on its impact on disease diagnosis, treatment, and prevention. By integrating large-scale data analysis, computational algorithms, and biological knowledge, bioinformatics has revolutionized our understanding of animal diseases, their genetic basis, and their interaction with the environment. The article …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 12, Issue 1, 2023 · pp. 21–26 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article