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84 articles for “dosage form”
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Pediatric and Geriatric Formulation Tailoring Dosage Form for Age-Specific Needs
Abstract: This comprehensive review addresses the critical challenges and advancements in the formulation of oral medications for pediatric and geriatric populations, who often face unique pharmacokinetic and pharmacodynamic differences. The World Health Organization highlights that nearly 50% of long-term medications are not adhered to, with significant implications for health outcomes. Pediatric patients, due to their developmental stages, and geriatric patients, due to age-related physiological changes, require tailored drug formulations to enhance …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 89–103 Read article
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Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Forms
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Adaptogenic Action of Different Dosage Forms of Guduchi with Special Reference to Learning and Memory
Abstract: The effect of three dosages forms of Guduchi (Satva 125 mg/kg, Ghana, 50 mg/kg, Churna 200 mg/kg) are compared with control and Piracetam (500 mg/kg) treated experimental animals in morris water maze test and passive avoidance test. The aim of the paper is to evaluate the nootropic effect of three dosages forms of Guduchi. Guduchi Satva, Ghana and Churna was prepared following the classical methods. For experimental study, animals were …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 1, 2015 · pp. 24–29 Read article
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A Literature Review on Various Ayurveda Dosage Forms
Abstract: Ayurveda is an ancient system of medical science which elucidates about the different forms of dosage, which is the physical form of a medication deliberate for administration. As per Ayurveda the different types of dosage forms can be prepared by the Vaidya (physician) according to Yukti (solution by scientific logic), seeing samyoga, vishesha, kala and samskara. Different types of dosage forms have been described in the Ayurvedic texts. These all …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 5, Issue 3, 2018 · pp. 19–23 Read article
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Development and validation of a method for simulataneous determination of tenovifir disoproxil fumarate emtriculabine and isonized in bulk and pharmaceutical dosage form using RP-HPLC with relevance to toxicological aspects
Abstract: Hence, proposed analytical methods are simple, novel, economical, rapid, sensitive, reproducible and accurate for the Simultaneous estimation of Tenofovir Disoproxil Fumarate, Emtricitabine and Isoniazid in Bulk and Phamaceutical dosage form by using RP- HPLC. This Method gives reliable assay results with short analysis time using mobile phase of Acetonitrile : 0.02M Potassium Dihydrogen Orthophosphate: water (pH 5.3) in the ratio of 60: 25: 15 respectively. Retention time was found to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 17–25 Read article
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Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article
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A New Separation Technique for Method, Development and Validation of Aclidinium Bromide and Formoterol Fumarate in Its Pure and Pharmaceutical Dosage Form by Using Rp-HPLC
Abstract: A new simple, precise, selective and accurate, a new method of development and validation using Rp-HPLC for the estimation of Aclidinium bromide and Formoterol Fumarate in its pure and pharmaceutical dosage form. Chromatogram was run through DIKMA Spursil, C18 segment (4.6×150 mm, 5µ0). Mobile phases contain 0.1% OPA: Acetonitrile (30:70) with the use of the 0.1% OPA buffer, stream rate of 1 ml/min and measured in 280 nm. The run …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 18–36 Read article
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Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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RP-HPLC method for simultaneous determination of Drospirenone and Ethinylestradiol in Bulk and their Pharmaceutical dosage form
Abstract: Oral contraceptive is used to prevent the pregnancy which is contain hormones to block the release of eggs from the ovaries. Most of them contain estrogen and progesterone. Nowadays, usage of hormonal contraceptive is sharply enhancing; around 100 million of women worldwide are taking these drugs. With this drug fertility rate can be supressed as long as they want or plan their activity along with these drugs provide efficacy, reliability, …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 46–67 Read article
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A Review of Analytical Method Development and Validation of Amiodarone Pharmaceutical Dosage Form
Abstract: The review provides an in-depth analysis of the analytical method development and validation process for amiodarone tablets. Method validation is crucial in the pharmaceutical industry for ensuring the quality and efficacy of tablets, as it ensures the accuracy, precision, and reliability of analytical techniques used in drug testing. It is a prerequisite for method development, adhering to good manufacturing practices, and optimizing processes. This review aims to consolidate and analyse …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 59–71 Read article
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Formulation and Evaluation of Unani Anti-acne Cream
Abstract: In unani system of medicine (USM) many herbal drugs have been mentioned to be useful in the treatment of various skin diseases, which are considered safe and free from major side effects. Most of the formulations for topical application are in powder form and patients feel inconvenience in using traditional dosage forms in comparison to modern dosage forms. Therefore in the present study a formula (in powder form) for acne …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2016 · pp. 17–22 Read article
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Chewable Healthcare: The Rising Impact of Gummy Supplements in Modern Medicine
Abstract: Gummy supplements, a chewable dosage form historically associated with pediatric vitamin products, are increasingly recognized as a versatile platform for delivering a wide range of nutraceutical and pharmaceutical agents. Their consumer appeal lies in their palatability, convenience, and the ability to overcome swallowing difficulties—a significant barrier to adherence in multiple patient populations. Recent advances in formulation science have expanded the potential of gummy supplements beyond basic vitamin delivery to include …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 52–68 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Analytical Method Development and Validation for Simultaneous Estimation of Paracetamol and Piroxicam by UV Method
Abstract: A new establishment and validation of a simple, precise, accurate and cost effective UV-Visible spectrophotometric method was developed to estimate both Paracetamol and Piroxicam simultaneously in conjoined pharmaceutical dosage forms. This technique was founded on simultaneous equation method of absorbances recorded at 252.0 nm and 282.0 nm of Paracetamol and Piroxicam in methanol respectively and an isosbestic point could be observed at 265.0 nm. It showed very good linearity over …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 14–21 Read article
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Stomach Mimicry of A-Forte for Pharmacokinetic Insight
Abstract: Drug absorption from solid dosage forms after oral administration depends on the release of the drug substance from the drug product, the dissolution or solubilization of the drug under physiological conditions, and the permeability across the gastrointestinal tract. In vitro dissolution may be relevant to the prediction of in vivo performance. To evaluate the in vitro dissolution of A-forte, a siddha proprietary medicine and the influencing factors, a study of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 2, 2015 · pp. 8–12 Read article
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Process Validation of Kushtasazi in the Preparation of Kushtae Sadaf
Abstract: The available forms of formulations in the Unani System of Medicine (USM) intended to treat the diseases either in semisolid sweetened forms such as Majoon, Jawarish, Khameera, Laooq, Itrifal or in liquid and dried forms such as Sharbat (Syrup), Arq (Distillate), Habb (Pil), Qurs (Tablet), Safoof (Powder), etc. There are large number of dosage forms used in the USM. Kushta (Calx) is also one among these compound formulations which is …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 2, 2017 · pp. 23–29 Read article
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Need of Standardization of Habb: A Unani Medicine
Abstract: Habb (pill) is a solid dosage form for oral administration of drugs in the human body. The present challenge for Unani scholars is to validate the claims made in the classical texts by applying scientific methodologies on this important dosage form. These claims need to be validated and the drugs need to be standardized on more precise scientific parameters. In order to have a good coordination between the quality of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 2, 2017 · pp. 37–45 Read article
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Child Friendly Innovation: A New Era in Pediatrics Drug Delivery Systems
Abstract: Pediatric formulations are becoming more and more popular as a result of advancements in pharmaceutical delivery technology. For young patients, there isn't a safe and effective drug delivery system in place. Since children's pharmacokinetics and pathophysiologic profiles differ from those of adults, it is imperative to design and develop an innovative and appropriate delivery system to provide accurate and dependable medicine administration to pediatric patients. Discussions will be held under …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article